Lista de

binding affinity
108
"Structure and dynamics of neurosteroid binding to the α1β2γ2 GABAA receptor" (2018) Alvarez, L.D.; Pecci, A. Journal of Steroid Biochemistry and Molecular Biology. 182:72-80
"Short linear motif core and flanking regions modulate retinoblastoma protein binding affinity and specificity" (2018) Palopoli, N.; Foutel, N.S.G.; Gibson, T.J.; Chemes, L.B. Protein Engineering, Design and Selection. 31(3):69-77
"Induction of ATP release, PPIX transport, and cholesterol uptake by human red blood cells using a new family of TSPO ligands" (2018) Marginedas-Freixa, I.;Alvarez, C.L.;Moras, M. (...)Ostuni, M.A. International Journal of Molecular Sciences. 19(10)
"Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase" (2018) Zhang, X.;Cao, S.;Barila, G. (...)Altschuler, D.L. Journal of Biological Chemistry. 293(20)
"High molecular weight components containing N-linked oligosaccharides of Ascaris suum extract inhibit the dendritic cells activation through DC-SIGN and MR" (2017) Favoretto, B.C.;Casabuono, A.A.C.;Portes-Junior, J.A. (...)Faquim-Mauro, E.L. Molecular Immunology. 87:33-46
"Heteromerization between the Bradykinin B2 Receptor and the Angiotensin-(1-7) Mas Receptor: Functional Consequences" (2016) Cerrato, B.D.;Carretero, O.A.;Janic, B. (...)Gironacci, M.M. Hypertension. 68(4):1039-1048
"Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Drug Discovery. 11(3):307-320
"Structural Plasticity in Globins: Role of Protein Dynamics in Defining Ligand Migration Pathways" (2016) Estarellas, C.;Capece, L.;Seira, C. (...)Christov C.Z. Advances in Protein Chemistry and Structural Biology. 105:59-80
"Anti-hemagglutinin antibody derived lead peptides for inhibitors of influenza virus binding" (2016) Memczak, H.;Lauster, D.;Kar, P. (...)Stöcklein, W.F.M. PLoS ONE. 11(7)
"Convergent evolution and mimicry of protein linear motifs in host-pathogen interactions" (2015) Chemes, L.B.; de Prat-Gay, G.; Sánchez, I.E. Current Opinion in Structural Biology. 32:91-101
"A computational study of the interaction of the foot and mouth disease virus VP1 with monoclonal antibodies" (2015) Marrero, R.;Limardo, R.R.;Carrillo, E. (...)Turjanski, A.G. Journal of Immunological Methods. 425:51-57
"Exploring the molecular basis of neurosteroid binding to the β3 homopentameric GABAA receptor" (2015) Alvarez, L.D.; Estrin, D.A. Journal of Steroid Biochemistry and Molecular Biology. 154:159-167
"Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood" (2015) Nasif, S.;De Souza, F.S.J.;González, L.E. (...)Rubinstein, M. Proceedings of the National Academy of Sciences of the United States of America. 112(15):E1861-E1870
"Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling" (2015) Samaniego Lopez, C.;Lago Huvelle, M.A.;Uhrig, M.L. (...)Spagnuolo, C.C. Chemical Communications. 51(23):4895-4898
"Low affinity binding site clusters confer HOX specificity and regulatory robustness" (2015) Crocker, J.;Abe, N.;Rinaldi, L. (...)Stern, D.L. Cell. 160(1-2):191-203
"Structural basis of redox-dependent modulation of galectin-1 dynamics and function" (2014) Guardia, C.M.;Caramelo, J.J.;Trujillo, M. (...)Rabinovich, G.A. Glycobiology. 24(5):428-441
"Interaction of cationic phthalocyanines with DNA. Importance of the structure of the substituents" (2014) López Zeballos, N.C.;Gauna, G.A.;García Vior, M.C. (...)Dicelio, L.E. Journal of Photochemistry and Photobiology B: Biology. 136:29-33
"Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain" (2014) Aran, M.;Smal, C.;Pellizza, L. (...)Cicero, D.O. Proteins: Structure, Function and Bioinformatics. 82(11):3062-3078
"Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: Implications for amyotrophic lateral sclerosis" (2014) Lu, L.;Zheng, L.;Si, Y. (...)King, P.H. Journal of Biological Chemistry. 289(46):31792-31804
"27-Nor-Δ4-dafachronic acid is a synthetic ligand of Caenorhabditis elegans DAF-12 receptor" (2013) Samaja, G.A.;Castro, O.;Alvarez, L.D. (...)Burton, G. Bioorganic and Medicinal Chemistry Letters. 23(10):2893-2896
"Pb(II) binding to humic substances: An equilibrium and spectroscopic study" (2013) Orsetti, S.; Marco-Brown, J.L.; Andrade, E.M.; Molina, F.V. Environmental Science and Technology. 47(15):8325-8333
"Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor" (2013) Rey, M.;Kruse, M.S.;Alvarez, L.D. (...)Coirini, H. Experimental Neurology. 249:49-58
"The allosteric modulation of thyroxine-binding globulin affinity is entropy driven" (2013) Petruk, A.A.; Labanda, M.S.; Álvarez, R.M.S.; Marti, M.A. Biochimica et Biophysica Acta - General Subjects. 1830(6):3570-3577
"Osmotic stress adaptation in Lactobacillus casei BL23 leads to structural changes in the cell wall polymer lipoteichoic acid" (2013) Palomino, M.M.;Allievi, M.C.;Gründling, A. (...)Ruzal, S.M. Microbiology (United Kingdom). 159(PART11):2416-2426
"Identification and characterization of a high-affinity choline uptake system of Brucella abortus" (2013) Herrmann, C.K.;Bukata, L.;Melli, L. (...)Comerci, D.J. Journal of Bacteriology. 195(3):493-501
"A two-stage model for lipid modulation of the activity of integral membrane proteins" (2012) Dodes Traian, M.M.; Cattoni, D.I.; Levi, V.; González Flecha, F.L. PLoS ONE. 7(6)
"Inhibition of Cell Division Induced by External Guide Sequences (EGS Technology) Targeting ftsZ" (2012) Sala, C.D.;Soler-Bistué, A.J.C.;Korprapun, L. (...)Tolmasky, M.E. PLoS ONE. 7(10)
"Interactions between β-lactoglobulin and casein glycomacropeptide on foaming" (2012) Martinez, M.J.; Carrera Sánchez, C.; Rodríguez Patino, J.M.; Pilosof, A.M.R. Colloids and Surfaces B: Biointerfaces. 89(1):234-241
"Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells 1" (2012) Cánepa, G.E.;Degese, M.S.;Budu, A. (...)Buscaglia, C.A. Biochemical Journal. 444(2):211-218
"E2→E1 transition and Rb+ release induced by Na+ in the Na+/K+-ATPase. Vanadate as a tool to investigate the interaction between Rb+ and E2" (2012) Montes, M.R.; Monti, J.L.E.; Rossi, R.C. Biochimica et Biophysica Acta - Biomembranes. 1818(9):2087-2093
"5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura)" (2012) Tesone, A.J.; Regueira, E.; Fabián Canosa, L.; Ceballos, N.R. General and Comparative Endocrinology. 176(3):500-506
"Expanding the universe of cytokines and pattern recognition receptors: Galectins and glycans in innate immunity" (2011) Cerliani, J.P.;Stowell, S.R.;Mascanfroni, I.D. (...)Rabinovich, G.A. Journal of Clinical Immunology. 31(1):10-21
"Trypanosoma cruzi amino acid transporter TcAAAP411 mediates arginine uptake in yeasts" (2010) Carrillo, C.;Canepa, G.E.;Giacometti, A. (...)Pereira, C.A. FEMS Microbiology Letters. 306(2):97-102
"Gender differences in 1,25 dihydroxyvitamin D3 immunomodulatory effects in multiple sclerosis patients and healthy subjects" (2010) Correale, J.; Ysrraelit, M.C.; Gaitan, M.I. Journal of Immunology. 185(8):4948-4958
"Synthesis and GABAA receptor activity of A-homo analogues of neuroactive steroids" (2010) Dansey, M.V.;Di Chenna, P.H.;Veleiro, A.S. (...)Burton, G. European Journal of Medicinal Chemistry. 45(7):3063-3069
"Sulfide binding properties of truncated hemoglobins" (2010) Nicoletti, F.P.;Comandini, A.;Bonamore, A. (...)Boffi, A. Biochemistry. 49(10):2269-2278
"Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids" (2010) Presman, D.M.;Alvarez, L.D.;Levi, V. (...)Pecci, A. PLoS ONE. 5(10)
"Acute modulation of calcium currents and synaptic transmission by gabapentinoids" (2010) Uchitel, O.D.; Di Guilmi, M.N.; Urbano, F.J.; Inchauspe, C.G. Channels. 4(6)
"Molecular basis of coupled protein and electron transfer dynamics of cytochrome c in biomimetic complexes" (2010) Alvarez-Paggi, D.;Martín, D.F.;Debiase, P.M. (...)Murgida, D.H. Journal of the American Chemical Society. 132(16):5769-5778
"New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects" (2009) Pecci, A.;Alvarez, L.D.;Veleiro, A.S. (...)Burton, G. Journal of Steroid Biochemistry and Molecular Biology. 113(3-5):155-162
"7-aminoactinomycin binding to DNA sequences lacking GpC sites: A thermodynamic and kinetic study" (2009) Biver, T.;Venturini, M.;Jares-Erijman, E.A. (...)Secco, F. Biochemistry. 48(1):173-179
"Structure-activity relationships of neuroactive steroids acting on the GABAA receptor" (2009) Veleiro, A.S.; Burton, G. Current Medicinal Chemistry. 16(4):455-472
"Synthesis and GABAA receptor activity of 2,19-sulfamoyl analogues of allopregnanolone" (2009) Durán, F.J.;Edelsztein, V.C.;Ghini, A.A. (...)Burton, G. Bioorganic and Medicinal Chemistry. 17(18):6526-6533
"Application of a constrained regularization method to extraction of affinity distributions: Proton and metal binding to humic substances" (2009) Orsetti, S.; Andrade, E.M.; Molina, F.V. Journal of Colloid and Interface Science. 336(2):377-387
"Glutamatergic system: Another target for the action of porphyrinogenic agents" (2009) Lavandera, J.V.;Fossati, M.;Azcurra, J. (...)Buzaleh, A.M. Cellular and Molecular Biology. 55(1):23-28
"Bond or cage effect: How nitrophorins transport and release nitric oxide" (2008) Martí, M.A.; González Lebrero, M.C.; Roitberg, A.E.; Estrin, D.A. Journal of the American Chemical Society. 130(5):1611-1618
"Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone" (2008) Álvarez, L.D.;Martí, M.A.;Veleiro, A.S. (...)Burton, G. Journal of Medicinal Chemistry. 51(5):1352-1360
"Effects of phosphatidylethanolamine glycation on lipid-protein interactions and membrane protein thermal stability" (2008) Levi, V.;Villamil Giraldo, A.M.;Castello, P.R. (...)González Flecha, F.L. Biochemical Journal. 416(1):145-152
"Functions of cell surface galectin-glycoprotein lattices" (2007) Rabinovich, G.A.; Toscano, M.A.; Jackson, S.S.; Vasta, G.R. Current Opinion in Structural Biology. 17(5):513-520
"Hexachlorobenzene as hormonal disruptor-studies about glucocorticoids: Their hepatic receptors, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis" (2007) Lelli, S.M.;Ceballos, N.R.;Mazzetti, M.B. (...)San Martín de Viale, L.C. Biochemical Pharmacology. 73(6):873-879
"Sperm protein "DE" mediates gamete fusion through an evolutionarily conserved site of the CRISP family" (2006) Ellerman, D.A.;Cohen, D.J.;Da Ros, V.G. (...)Cuasnicú, P.S. Developmental Biology. 297(1):228-237
"Novel cysteine proteinase in Trypanosoma cruzi metacyclogenesis" (2006) Duschak, V.G.;Barboza, M.;García, G.A. (...)Isola, E.L.D. Parasitology. 132(3):345-355
"Heme protein oxygen affinity regulation exerted by proximal effects" (2006) Capece, L.;Marti, M.A.;Crespo, A. (...)Estrin, D.A. Journal of the American Chemical Society. 128(38):12455-12461
"Binding of a single Rb+ increases Na+/K +-ATPase, activating dephosphorylation without stoichiometric occlusion" (2006) Kaufman, S.B.; González-Lebrero, R.M.; Rossi, R.C.; Garrahan, P.J. Journal of Biological Chemistry. 281(23):15721-15726
"Nucleoside phosphorylases" (2006) Lewkowicz, E.S.; Iribarren, A.M. Current Organic Chemistry. 10(11):1197-1215
"Dioxygen affinity in heme proteins investigated by computer simulation" (2006) Marti, M.A.;Crespo, A.;Capece, L. (...)Estrin, D.A. Journal of Inorganic Biochemistry. 100(4):761-770
"Heparin increases the adhesion of murine mammary adenocarcinoma cells (LM3). Correlation with the presence of heparin receptors on cell surface" (2005) Bertolesi, G.; Eijan, A.M.; Calvo, J.C.; de Cidre, L.L. Journal of Biological Regulators and Homeostatic Agents. 19(1-2):33-40
"Effects of quinine, quinidine, and chloroquine on α9α10 nicotinic cholinergic receptors" (2005) Ballestero, J.A.;Plazas, P.V.;Kracun, S. (...)Elgoyhen, A.B. Molecular Pharmacology. 68(3):822-829
"Binding of recombinant human proacrosin/acrosin to zona pellucida glycoproteins. II. Participation of mannose residues in the interaction" (2005) Furlong, L.I.; Veaute, C.; Vazquez-Levin, M.H. Fertility and Sterility. 83(6):1791-1796
"Differential modulation of MAP kinases by zinc deficiency in IMR-32 cells: Role of H2O2" (2005) Zago, M.P.;Mackenzie, G.G.;Adamo, A.M. (...)Oteiza, P.I. Antioxidants and Redox Signaling. 7(11-12):1773-1782
"Free energy contributions to direct readout of a DNA sequence" (2005) Ferreiro, D.U.; Dellarole, M.; Nadra, A.D.; De Prat-Gay, G. Journal of Biological Chemistry. 280(37):32480-32484
"The folding mechanism of a dimeric β-barrel domain" (2005) De Prat-Gay, G.;Nadra, A.D.;Corrales-Izquierdo, F.J. (...)Mok, Y.-K. Journal of Molecular Biology. 351(3):672-682
"Binding of recombinant human proacrosin/acrosin to zona pellucida (ZP) glycoproteins. I. Studies with recombinant human ZPA, ZPB, and ZPC" (2005) Furlong, L.I.; Harris, J.D.; Vazquez-Levin, M.H. Fertility and Sterility. 83(6):1780-1790
"A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between Rat α9α10 and α7 nicotinic cholinergic receptors" (2005) McIntosh, J.M.;Plazas, P.V.;Watkins, M. (...)Elgoyhen, A.B. Journal of Biological Chemistry. 280(34):30107-30112
"Ligand-induced thermostability in proteins: Thermodynamic analysis of ANS-albumin interaction" (2005) Celej, M.S.;Dassie, S.A.;Freire, E. (...)Fidelio, G.D. Biochimica et Biophysica Acta - Proteins and Proteomics. 1750(2):122-133
"Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of pregnanesteroids" (2004) Galigniana, M.D.;Pilipuk, G.P.;Kanelakis, K.C. (...)Lantos, C.P. Molecular and Cellular Endocrinology. 217(1-2):167-179
"Synthesis and characterization of a chimeric peptide derived from fasciculin that inhibits acetylcholinesterase" (2004) Falkenstein, R.J.; Gornalusse, G.G.; Peña, C. Journal of Peptide Science. 10(6):342-349
"NMR and molecular dynamics studies of the interaction of melatonin with calmodulin" (2004) Turjanski, A.G.;Estrin, D.A.;Rosenstein, R.E. (...)Martorana, V. Protein Science. 13(11):2925-2938
"Specific antibody - DNA interaction: A novel strategy for fight dna recognition" (2003) Di Pietro, S.M.;Centeno, J.M.;Cerutti, M.L. (...)De Prat-Gay, G. Biochemistry. 42(20):6218-6227
"Sequence analysis, expression, and paratope characterization of a single-chain Fv fragment for the eukaryote ribosomal P proteins" (2003) López Bergami, P.;Mateos, P.;Hoebeke, J. (...)Baldi, A. Biochemical and Biophysical Research Communications. 301(4):819-824
"Topological and NBO analysis of hydrogen bonding interactions involving C-H···O bonds" (2002) Sosa, G.L.; Peruchena, N.M.; Contreras, R.H.; Castro, E.A. Journal of Molecular Structure: THEOCHEM. 577(2-3):219-228
"Antithrombin and first complement protein recognize the same active heparin fraction" (2002) Calabrese, G.C.; Recondo, E.F.; Fernandez De Recondo, M.E. Thrombosis Research. 105(6):537-541
"A novel calcium-stimulated adenylyl cyclase from Trypanosoma cruzi, which interacts with the structural flagellar protein paraflagellar rod" (2002) D'Angelo, M.A.;Montagna, A.E.;Sanguineti, S. (...)Flawiá, M.M. Journal of Biological Chemistry. 277(38):35025-35034
"Aluminum toxicity in Erythropoiesis. Related mechanisms " (2002) Pérez, G.; Vittori, D.; Garbossa, G.; Nesse, A. Acta Bioquimica Clinica Latinoamericana. 36(1):41-50
"Correlation between pregnanesteroid conformation, receptor affinity, and anti-natriuretic effect" (2002) Piwien-Pilipuk, G.; Kanelakis, K.C.; Galigniana, M.D. European Journal of Pharmacology. 454(2-3):131-143
"Further evidence for the critical role of a non-chair conformation of L-iduronic acid in the activation of antithrombin" (2002) Kovensky, J.;Mallet, J.-M.;Esnault, J. (...)Sinaÿ, P. European Journal of Organic Chemistry(21):3595-3603
"Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes" (2002) Rodriguez, M.E.; Awruch, J.; Dicelio, L. Journal of Porphyrins and Phthalocyanines. 6(2):122-129
"Generation of Sequence-specific, High Affinity Anti-DNA Antibodies" (2001) Cerutti, M.L.; Centeno, J.M.; Goldbaum, F.A.; De Prat-Gay, G. Journal of Biological Chemistry. 276(16):12769-12773
"Synthesis and properties of (2′S)- and (2′R)-2′-deoxy-2′-C-methyl oligonucleotides" (2001) Cicero, D.O.; Gallo, M.; Neuner, P.J.; Iribarren, A.M. Tetrahedron. 57(36):7613-7621
"Disturbance of cellular iron uptake and utilisation by aluminium" (2001) Pérez, G.;Garbossa, G.;Di Risio, C. (...)Nesse, A. Journal of Inorganic Biochemistry. 87(1):21-27
"Binding of nicotinic ligands to and nicotine-induced calcium signaling in Trypanosoma cruzi" (2001) Bollo, M.; Venera, G.; de Jiménez Bonino, M.B.; Machado-Domenech, E. Biochemical and Biophysical Research Communications. 281(2):300-304
"Human p8 Is a HMG-I/Y-like Protein with DNA Binding Activity Enhanced by Phosphorylation" (2001) Encinar, J.A.;Mallo, G.V.;Mizyrycki, C. (...)Iovanna, J.L. Journal of Biological Chemistry. 276(4):2742-2751
"Evidence for the participation of β-hexosaminidase in human sperm-zona pellucida interaction in vitro" (2000) Miranda, P.V.;González-Echeverría, F.;Blaquier, J.A. (...)Tezón, J.G. Molecular Human Reproduction. 6(8):699-706
"Structural and functional analysis of the cAMP binding domain from the regulatory subunit of Mucor rouxii protein kinase A" (2000) Sorol, M.R.;Pastori, R.L.;Muro, A. (...)Rossi, S. Archives of Biochemistry and Biophysics. 382(2):173-181
"Activity of renal 11 βhydroxysteroid dehydrogenase 2 (11 βhsd2) in stressed animals" (1999) Igarreta, P.; Calvo, J.C.; Damasco, M.C. Life Sciences. 64(24):2285-2290
"Biosynthesis of progesterone derived neurosteroids by developing avian CNS : In vitro effects on the gabaa receptor complex" (1998) Pignataro, L.; Colman Lerner, A.A.; Barañao, J.L.; De Plazas, S.F. International Journal of Developmental Neuroscience. 16(5):433-442
"Micellar lipoproteins as the possible storage and translocation form of intracellular diacylglycerol" (1998) Florin-Christensen, J.;D'Alessio, C.;Arighi, C. (...)Delfino, J.M. Biochemical and Biophysical Research Communications. 243(3):669-673
"α-Difluoromethylornithine-resistant cell lines obtained after one-step selection of Leishmania mexicana promastigote cultures" (1997) Sánchez, C.P.;Mucci, J.;González, N.S. (...)Algranati, I.D. Biochemical Journal. 324(3):847-853