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Abstract:

This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological conditions. © The Royal Society of Chemistry 2015.

Registro:

Documento: Artículo
Título:Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling
Autor:Samaniego Lopez, C.; Lago Huvelle, M.A.; Uhrig, M.L.; Coluccio Leskow, F.; Spagnuolo, C.C.
Filiación:Dpto. de Química Orgánica, Universidad de Buenos Aires, Ciudad Universitaria, Cdad. Autonoma de Buenos Aires 3er piso Pabellon IIC1428EGA, Argentina
Departamento de Química Biológica, Universidad de Buenos Aires, Ciudad Universitaria, Cdad. Autonoma de Buenos Aires 2do piso Pabellon IIC1428EGA, Argentina
Palabras clave:boronic acid derivative; boronolectin; carbohydrate derivative; cyanine dye; fluorescent dye; tricarbocyanine; unclassified drug; water; boron derivative; boronolectin; carbohydrate; fluorescent dye; monosaccharide; Article; binding affinity; biocompatibility; cell labeling; cell viability; controlled study; drug solubility; field emission; fluorescence; human; human cell; in vitro study; molecular recognition; near infrared spectroscopy; sensitivity analysis; synthesis; animal; cell line; chemical structure; chemistry; fluorescence; sensitivity and specificity; Animals; Boron Compounds; Carbohydrates; Cell Line; Fluorescence; Fluorescent Dyes; Molecular Structure; Monosaccharides; Sensitivity and Specificity
Año:2015
Volumen:51
Número:23
Página de inicio:4895
Página de fin:4898
DOI: http://dx.doi.org/10.1039/c4cc10425k
Título revista:Chemical Communications
Título revista abreviado:Chem. Commun.
ISSN:13597345
CODEN:CHCOF
CAS:water, 7732-18-5; Boron Compounds; boronolectin; Carbohydrates; Fluorescent Dyes; Monosaccharides
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13597345_v51_n23_p4895_SamaniegoLopez

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Citas:

---------- APA ----------
Samaniego Lopez, C., Lago Huvelle, M.A., Uhrig, M.L., Coluccio Leskow, F. & Spagnuolo, C.C. (2015) . Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling. Chemical Communications, 51(23), 4895-4898.
http://dx.doi.org/10.1039/c4cc10425k
---------- CHICAGO ----------
Samaniego Lopez, C., Lago Huvelle, M.A., Uhrig, M.L., Coluccio Leskow, F., Spagnuolo, C.C. "Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling" . Chemical Communications 51, no. 23 (2015) : 4895-4898.
http://dx.doi.org/10.1039/c4cc10425k
---------- MLA ----------
Samaniego Lopez, C., Lago Huvelle, M.A., Uhrig, M.L., Coluccio Leskow, F., Spagnuolo, C.C. "Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling" . Chemical Communications, vol. 51, no. 23, 2015, pp. 4895-4898.
http://dx.doi.org/10.1039/c4cc10425k
---------- VANCOUVER ----------
Samaniego Lopez, C., Lago Huvelle, M.A., Uhrig, M.L., Coluccio Leskow, F., Spagnuolo, C.C. Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling. Chem. Commun. 2015;51(23):4895-4898.
http://dx.doi.org/10.1039/c4cc10425k