Artículo
Rodriguez, M.E.; Awruch, J.; Dicelio, L. "Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes" (2002) Journal of Porphyrins and Phthalocyanines. 6(2):122-129
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Abstract:
Amphiphilic phthalocyanines are used as potential photosensitizers in photodynamic therapy. The low water solubility of most of these dyes is the reason that different kinds of vehicles are employed as endogenous carriers. Due to the photophysical inactivity of the phthalocyanine aggregates, it is important to improve their solubility in order to study dyes in solid tumor models. On the other hand, the photodynamic therapy activity depends on the location of phthalocyanines in the cell and the interaction of cellular components. In this work, the photophysical properties of tetrasubstituted Zn(II) phthalocyanines with different lipophilic properties are incorporated into liposomes of L-α-dimyristoylphosphatidylcholine (DMPC). The fluorescence quantum yields, the association constants and their localization in the membranes are reported. Copyright © 2002 Society of Porphyrins & Phthalocyanines.
Registro:
| Documento: | Artículo |
| Título: | Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes |
| Autor: | Rodriguez, M.E.; Awruch, J.; Dicelio, L. |
| Filiación: | INQUIMAE, Departamento de Quimica Inorganica, Universidad de Buenos Aires, Ciudad Universitaria, (1428) Buenos Aires, Argentina |
| Palabras clave: | Association constant; Fluorescence quantum yields; Liposomes; PDT; Zinc phthalocyanine; dimyristoylphosphatidylcholine; liposome; photosensitizing agent; phthalocyanine derivative; unclassified drug; zinc derivative; zinc phthalocyaninate; article; binding affinity; chemical structure; drug solubility; fluorescence spectroscopy; lipophilicity; photodynamic therapy |
| Año: | 2002 |
| Volumen: | 6 |
| Número: | 2 |
| Página de inicio: | 122 |
| Página de fin: | 129 |
| DOI: | http://dx.doi.org/10.1142/S1088424602000166 |
| Título revista: | Journal of Porphyrins and Phthalocyanines |
| Título revista abreviado: | J. Porphyrins Phthalocyanines |
| ISSN: | 10884246 |
| CODEN: | JPPHF |
| CAS: | dimyristoylphosphatidylcholine, 13699-48-4, 18194-24-6 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10884246_v6_n2_p122_Rodriguez |
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Citas:
---------- APA ----------
Rodriguez, M.E., Awruch, J. & Dicelio, L. (2002) . Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes. Journal of Porphyrins and Phthalocyanines, 6(2), 122-129.http://dx.doi.org/10.1142/S1088424602000166
---------- CHICAGO ----------
Rodriguez, M.E., Awruch, J., Dicelio, L. "Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes" . Journal of Porphyrins and Phthalocyanines 6, no. 2 (2002) : 122-129.http://dx.doi.org/10.1142/S1088424602000166
---------- MLA ----------
Rodriguez, M.E., Awruch, J., Dicelio, L. "Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes" . Journal of Porphyrins and Phthalocyanines, vol. 6, no. 2, 2002, pp. 122-129.http://dx.doi.org/10.1142/S1088424602000166
---------- VANCOUVER ----------
Rodriguez, M.E., Awruch, J., Dicelio, L. Photophysical properties of Zn(II) phthalocyaninates incorporated into liposomes. J. Porphyrins Phthalocyanines. 2002;6(2):122-129.http://dx.doi.org/10.1142/S1088424602000166
