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glucocorticoid receptor
99
"Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus" (2019) Taves, M.D.;Mittelstadt, P.R.;Presman, D.M. (...)Ashwell, J.D. Cell Reports. 26(13):3629-3642.e4
"Mapping the dynamical organization of the cell nucleus through fluorescence correlation spectroscopy" (2018) Stortz, M.;Angiolini, J.;Mocskos, E. (...)Levi, V. Methods. 140-141:10-22
"Mapping the dynamical organization of the cell nucleus through fluorescence correlation spectroscopy" (2018) Stortz, M.;Angiolini, J.;Mocskos, E. (...)Levi, V. Methods. 140-141:10-22
"Regulatory and mechanistic actions of glucocorticoids on T and inflammatory cells" (2018) Liberman, A.C.;Budziñski, M.L.;Sokn, C. (...)Arzt, E. Frontiers in Endocrinology. 9(MAY)
"Synthesis of new C-25 and C-26 steroidal acids as potential ligands of the nuclear receptors DAF-12, LXR and GR" (2017) Dansey, M.V.; del Fueyo, M.C.; Veleiro, A.S.; Di Chenna, P.H. Steroids. 121:40-46
"Synthesis of new C-25 and C-26 steroidal acids as potential ligands of the nuclear receptors DAF-12, LXR and GR" (2017) Dansey, M.V.; del Fueyo, M.C.; Veleiro, A.S.; Di Chenna, P.H. Steroids. 121:40-46
"Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape" (2017) Stortz, M.;Presman, D.M.;Bruno, L. (...)Levi, V. Scientific Reports. 7(1)
"Biological relevance of Hsp90-binding immunophilins in cancer development and treatment" (2016) Mazaira, G.I.;Camisay, M.F.;De Leo, S. (...)Galigniana, M.D. International Journal of Cancer. 138(4):797-808
"21-hydroxy-6,19-epoxyprogesterone: A promising therapeutic agent and a molecular tool for deciphering glucocorticoid action" (2016) Pecci, A.; Alvarez, L.D.; Presman, D.M.; Burton, G. Mini-Reviews in Medicinal Chemistry. 16
"21-hydroxy-6,19-epoxyprogesterone: A promising therapeutic agent and a molecular tool for deciphering glucocorticoid action" (2016) Pecci, A.; Alvarez, L.D.; Presman, D.M.; Burton, G. Mini-Reviews in Medicinal Chemistry. 16
"Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine d2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance" (2016) Luque, G.M.;Lopez-Vicchi, F.;María Ornstein, A. (...)Becu-Villalobos, D. American Journal of Physiology - Endocrinology and Metabolism. 311(6):E974-E988
"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139
"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139
"The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51" (2016) Antunica-Noguerol, M.;Budziñski, M.L.;Druker, J. (...)Arzt, E. Cell Death and Differentiation. 23(10):1579-1591
"The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51" (2016) Antunica-Noguerol, M.;Budziñski, M.L.;Druker, J. (...)Arzt, E. Cell Death and Differentiation. 23(10):1579-1591
"Role of RSUME in inflammation and cancer" (2015) Antico Arciuch, V.G.; Tedesco, L.; Fuertes, M.; Arzt, E. FEBS Letters. 589(22):3330-3335
"Function and structure of the RWD domain" (2015) Páez-Pereda, M.; Arzt, E. Journal of Biological Chemistry. 290(33):20627
"The interplay between the glucocorticoid receptor activity and post-translational modifications in the immune and neuroendocrine systems" (2014) Antunica-Noguerol, M.;Aprile-Garcia, F.;Budziñski, M.L. (...)Arzt, E. Advances in Neuroimmune Biology. 5(1):19-32
"The interplay between the glucocorticoid receptor activity and post-translational modifications in the immune and neuroendocrine systems" (2014) Antunica-Noguerol, M.;Aprile-Garcia, F.;Budziñski, M.L. (...)Arzt, E. Advances in Neuroimmune Biology. 5(1):19-32
"The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice" (2014) Meyer, M.;Gonzalez Deniselle, M.C.;Hunt, H. (...)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 143:40-48
"The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice" (2014) Meyer, M.;Gonzalez Deniselle, M.C.;Hunt, H. (...)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 143:40-48
"NF-κB transcriptional activity is modulated by FK506-Binding proteins FKBP51 and FKBP52:A role for peptidyl-prolyl isomerase activity" (2014) Erlejman, A.G.;De Leo, S.A.;Mazaira, G.I. (...)Galigniana, M.D. Journal of Biological Chemistry. 289(38):26263-26276
"Hsp90-binding immunophilins as a potential new platform for drug treatment" (2013) Erlejman, A.G.; Lagadari, M.; Galigniana, M.D. Future Medicinal Chemistry. 5(5):591-607
"Molecular basis of mineralocorticoid receptor action in the nervous system" (2013) Molinari, A.M.;Machado-Rada, M.Y.;Mazaira, G.I. (...)Galigniana, M.D. CNS and Neurological Disorders - Drug Targets. 12(8):1163-1174
"Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions" (2013) Spallanzani, R.G.;Dalotto-Moreno, T.;Raffo Iraolagoitia, X.L. (...)Zwirner, N.W. Cancer Immunology, Immunotherapy. 62(12):1781-1795
"Steroid-dependent management of biological responses in the nervous system" (2013) Galigniana, M.D. CNS and Neurological Disorders - Drug Targets. 12(8):1143-1145
"RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity" (2013) Druker, J.;Liberman, A.C.;Antunica-Noguerol, M. (...)Arzta, E. Molecular and Cellular Biology. 33(11):2116-2127
"Seasonal Changes and Regulation of the Glucocorticoid Receptor in the Testis of the Toad Rhinella arenarum" (2013) Regueira, E.;Sassone, A.G.;Scaia, M.F. (...)Ceballos, N.R. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology. 319(1):39-52
"Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51" (2012) Galigniana, N.M.;Ballmer, L.T.;Toneatto, J. (...)Galigniana, M.D. Journal of Neurochemistry. 122(1):4-18
"Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51" (2012) Galigniana, N.M.;Ballmer, L.T.;Toneatto, J. (...)Galigniana, M.D. Journal of Neurochemistry. 122(1):4-18
"5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura)" (2012) Tesone, A.J.; Regueira, E.; Fabián Canosa, L.; Ceballos, N.R. General and Comparative Endocrinology. 176(3):500-506
"Melatonin inhibits glucocorticoid-dependent GR-TIF2 interaction in newborn hamster kidney (BHK) cells" (2012) Presman, D.M.; Levi, V.; Pignataro, O.P.; Pecci, A. Molecular and Cellular Endocrinology. 349(2):214-221
"Melatonin inhibits glucocorticoid-dependent GR-TIF2 interaction in newborn hamster kidney (BHK) cells" (2012) Presman, D.M.; Levi, V.; Pignataro, O.P.; Pecci, A. Molecular and Cellular Endocrinology. 349(2):214-221
"Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells" (2012) Montesinos, M.M.;Alamino, V.A.;Mascanfroni, I.D. (...)Pellizas, C.G. Steroids. 77(1-2):67-76
"Compound a, a dissociated glucocorticoid receptor modulator, inhibits t-bet (th1) and induces gata-3 (th2) activity in immune cells" (2012) Liberman, A.C.;Antunica-Noguerol, M.;Ferraz-de-Paula, V. (...)Arzt, E. PLoS ONE. 7(4)
"Compound a, a dissociated glucocorticoid receptor modulator, inhibits t-bet (th1) and induces gata-3 (th2) activity in immune cells" (2012) Liberman, A.C.;Antunica-Noguerol, M.;Ferraz-de-Paula, V. (...)Arzt, E. PLoS ONE. 7(4)
"Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52)" (2011) Sivils, J.C.; Storer, C.L.; Galigniana, M.D.; Cox, M.B. Current Opinion in Pharmacology. 11(4):314-319
"The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress" (2011) Gallo, L.I.; Lagadari, M.; Piwien-Pilipuk, G.; Galigniana, M.D. Journal of Biological Chemistry. 286(34):30152-30160
"The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress" (2011) Gallo, L.I.; Lagadari, M.; Piwien-Pilipuk, G.; Galigniana, M.D. Journal of Biological Chemistry. 286(34):30152-30160
"Role of molecular chaperones and TPR-domain proteins in the cytoplasmic transport of steroid receptors and their passage through the nuclear pore" (2010) Galigniana, M.D.; Echeverría, P.C.; Erlejman, A.G.; Piwien-Pilipuk, G. Nucleus. 1(4):299-308
"Molecular mechanisms of glucocorticoids action: From basic research to clinical implications" (2010) Liberman, A.C.;Castro, C.N.;Noguerol, M.A. (...)Arzt, E. Current Immunology Reviews. 6(4):371-380
"Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids" (2010) Presman, D.M.;Alvarez, L.D.;Levi, V. (...)Pecci, A. PLoS ONE. 5(10)
"Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids" (2010) Presman, D.M.;Alvarez, L.D.;Levi, V. (...)Pecci, A. PLoS ONE. 5(10)
"Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands" (2010) Veleiro, A.S.; Alvarez, L.D.; Eduardo, S.L.; Burton, G. ChemMedChem. 5(5):649-659
"Intracellular molecular signaling: Basis for specificity to glucocorticoid anti-inflammatory actions" (2009) Liberman, A.C.;Druker, J.;Garcia, F.A. (...)Arzt, E. Annals of the New York Academy of Sciences. 1153:6-13
"Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells" (2009) Liberman, A.C.;Druker, J.;Refojo, D. (...)Arzt, E. FASEB Journal. 23(5):1558-1571
"Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin β" (2009) Echeverría, P.C.;Mazaira, G.;Erlejman, A. (...)Galigniana, M.D. Molecular and Cellular Biology. 29(17):4788-4797
"Hemisuccinate of 21-hydroxy-6,19-epoxyprogesterone: A tissue-specific modulator of the glucocorticoid receptor" (2008) Álvarez, L.D.;Martí, M.A.;Veleiro, A.S. (...)Burton, G. ChemMedChem. 3(12):1869-1877
"Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone" (2008) Álvarez, L.D.;Martí, M.A.;Veleiro, A.S. (...)Burton, G. Journal of Medicinal Chemistry. 51(5):1352-1360
"Neuroimmune-endocrine interactions during early pregnancy in an autoimmune context: Focus on macrophage activation" (2008) Larocca, L.;Ramhorst, R.;Roca, V. (...)Pérez Leirós, C. NeuroImmunoModulation. 15(1):84-90
"Glucocorticoids in the regulation of transcription factors that control cytokine synthesis" (2007) Liberman, A.C.; Druker, J.; Perone, M.J.; Arzt, E. Cytokine and Growth Factor Reviews. 18(1-2):45-56
"Genes involved in the balance between neuronal survival and death during inflammation" (2007) Glezer, I.;Chernomoretz, A.;David, S. (...)Rivest, S. PLoS ONE. 2(3)
"Hexachlorobenzene as hormonal disruptor-studies about glucocorticoids: Their hepatic receptors, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis" (2007) Lelli, S.M.;Ceballos, N.R.;Mazzetti, M.B. (...)San Martín de Viale, L.C. Biochemical Pharmacology. 73(6):873-879
"The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction" (2007) Liberman, A.C.;Refojo, D.;Druker, J. (...)Arzt, E. FASEB Journal. 21(4):1177-1188
"Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes" (2006) Presman, D.M.;Hoijman, E.;Ceballos, N.R. (...)Pecci, A. Endocrinology. 147(11):5452-5459
"Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to the P4 promoter" (2006) Rocha-Viegas, L.;Vicent, G.P.;Barañao, J.L. (...)Pecci, A. Journal of Biological Chemistry. 281(45):33959-33970
"Molecular understanding of cytokine-steroid hormone dialogue: Implications for human diseases" (2006) Druker, J.;Liberman, A.C.;Acuña, M. (...)Arzt, E. Annals of the New York Academy of Sciences. 1088:297-306
"Evidence for glucocorticoid receptor transport on microtubules by dynein" (2004) Harrell, J.M.;Murphy, P.J.M.;Morishima, Y. (...)Pratt, W.B. Journal of Biological Chemistry. 279(52):54647-54654
"Integrating systemic information at the molecular level: Cross-talk between steroid receptors and cytokine signaling on different target cells" (2003) Refojo, D.;Liberman, A.C.;Giacomini, D. (...)Arzt, E. Annals of the New York Academy of Sciences. 992:196-204
"Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific responses" (2002) Vicent, G.P.;Pecci, A.;Ghini, A. (...)Galigniana, M.D. Experimental Cell Research. 276(2):142-154
"gp130 cytokine signaling in the pituitary gland: A paradigm for cytokine-neuro-endocrine pathways" (2001) Arzt, E. Journal of Clinical Investigation. 108(12):1729-1733
"Molecular mechanisms and Th1/Th2 pathways in corticosteroid regulation of cytokine production" (2000) Kovalovsky, D.; Refojo, D.; Holsboer, F.; Arzt, E. Journal of Neuroimmunology. 109(1):23-29
"Transrepression of NF-κB is not required for glucocorticoid-mediated protection of TNF-α-induced apoptosis on fibroblasts" (2000) Costas, M.A.; Müller Igaz, L.; Holsboer, F.; Arzt, E. Biochimica et Biophysica Acta - Molecular Cell Research. 1499(1-2):122-129
"Transrepression of NF-κB is not required for glucocorticoid-mediated protection of TNF-α-induced apoptosis on fibroblasts" (2000) Costas, M.A.; Müller Igaz, L.; Holsboer, F.; Arzt, E. Biochimica et Biophysica Acta - Molecular Cell Research. 1499(1-2):122-129
"Transrepression of NF-κB is not required for glucocorticoid-mediated protection of TNF-α-induced apoptosis on fibroblasts" (2000) Costas, M.A.; Müller Igaz, L.; Holsboer, F.; Arzt, E. Biochimica et Biophysica Acta - Molecular Cell Research. 1499(1-2):122-129
"RAC-3 is a NF-κB coactivator" (2000) Werbajh, S.; Nojek, I.; Lanz, R.; Costas, M.A. FEBS Letters. 485(2-3):195-199
"RAC-3 is a NF-κB coactivator" (2000) Werbajh, S.; Nojek, I.; Lanz, R.; Costas, M.A. FEBS Letters. 485(2-3):195-199
"Glucocorticoid-induced apoptosis: A simple set of laboratory experiments" (2000) Vicent, G.P.;Lanuza, G.M.;Romero, D.G. (...)Pecci, A. Biochemistry and Molecular Biology Education. 28(6):307-312
"Functional cross-talk among cytokines, T-cell receptor, and glucocorticoid receptor transcriptional activity and action" (2000) Arzt, E.;Kovalovsky, D.;Müller Igaz, L. (...)Holsboer, F. Annals of the New York Academy of Sciences. 917:672-677
"Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives" (1998) Vicent, G.P.;Burton, G.;Ghini, A. (...)Galigniana, M.D. Journal of Steroid Biochemistry and Molecular Biology. 66(4):211-216
"Glucocorticoid receptors and actions in the spinal cord of the Wobbler mouse a model for neurodegenerative diseases" (1997) González Deniselle, M.C.;González, S.;Piroli, G. (...)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 60(3-4):205-213
"21-hydroxy-6,19-oxidoprogesterone: A novel synthetic steroid with specific antiglucocorticoid properties in the rat" (1997) Vicent, G.P.;Monteserín, M.C.;Veleiro, A.S. (...)Galigniana, M.D. Molecular Pharmacology. 52(4):749-753
"Glucocorticoid regulation of in vitro astrocyte phagocytosis" (1997) Roldán, A.;Gogg, S.;Ferrini, M. (...)De Nicola, A.F. Biocell. 21(1):83-89
"The 21-aminosteroid U-74389F increases the number of glial fibrillary acidic protein-expressing astrocytes in the spinal cord of control and Wobbler mice" (1996) Deniselle, M.C.G.;Gonzalez, S.L.;Piroli, G.G. (...)De Nicola, A.F. Cellular and Molecular Neurobiology. 16(1):61-72
"Estradiol abolishes autologous down regulation of glucocorticoid receptors in brain" (1995) Ferrini, M.; Lima, A.; De Nicola, A.F. Life Sciences. 57(26):2403-2412
"Binding of the anti-inflammatory steroid deflazacort to glucocorticoid receptors in brain and peripheral tissues. In vivo and in vitro studies" (1994) Coirini, H.;Flores, D.;Cristina Vega, M. (...)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 49(1):43-49
"Glucocorticoid type II receptors of the spinal cord show lower affinity than hippocampal type II receptors: Binding parameters obtained with different experimental protocols" (1991) Moses, D.F.; González, S.; McEwen, B.S.; De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 39(1):5-12
"Glucocorticoid type II receptors of the spinal cord show lower affinity than hippocampal type II receptors: Binding parameters obtained with different experimental protocols" (1991) Moses, D.F.; González, S.; McEwen, B.S.; De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 39(1):5-12
"Glucocorticoid receptors and inhibition of serum prolactin by dexamethasone are reduced in rats with estrogen-induced pituitary tumors" (1991) Piroli, G.;Grillo, C.;Lux de Lantos, V. (...)De Nicola, A.F. Neuroendocrinology Letters. 13(2):75-81
"Adrenocorticoid action in the spinal cord: Some unique molecular properties of glucocorticoid receptors" (1989) De Nicola, A.F.; Moses, D.F.; González, S.; Ortí, E. Cellular and Molecular Neurobiology. 9(2):179-192
"Functions and dysfunctions of receptors for adrenal corticoids in the central nervous system" (1987) De Nicola, A.F.;Ortí, E.;Moses, D.F. (...)Coirini, H. Journal of Steroid Biochemistry. 27(1-3):599-607
"Properties and distribution of glucocorticoid-binding sites in cytosol of the spinal cord" (1985) Orti, E.; Coirini, H.; De Nicola, A.F. Neuroendocrinology. 40(3):225-231
"Influence of phosphatase inhibitors and nucleotides on [3H]dexamethasone binding in cytosol of human placenta" (1984) Heller, C.; Coirini, H.; de Nicola, A.F. Journal of Steroid Biochemistry. 21(4):381-386
"Binding of [3H]dexamethasone by rat placenta" (1981) Heller, C.; Coirini, H.; De Nicola, A.F. Endocrinology. 108(5):1697-1702
"Reduction in [3H]-corticosterone binding to cytoplasmic receptors in the brain of diabetic rats" (1978) Fridman, O.; Foglia, V.G.; De Nlcola, A.F. Journal of Steroid Biochemistry. 9(7):609-614