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Referencias:

• Chrousos, G.P., The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation (1995) N. Engl. J. Med., 332, pp. 1351-1362
• Cippitelli, M., Sica, A., Viggiano, V., Ye, J., Ghosh, P., Birrer, M.J., Young, H.A., Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun (1995) J. Biol. Chem., 270, pp. 12548-12556
• Ashwell, J.D., Lu, F.W., Vacchio, M.S., Glucocorticoids in T cell development and function (2000) Annu. Rev. Immunol., 18, pp. 309-345
• Cupps, T.R., Fauci, A.S., Corticosteroid-mediated immunoregulation in man (1982) Immunol. Rev., 65, pp. 133-155
• Kovalovsky, D., Pereda, M.P., Sauer, J., Castro, C.P., Nahmod, V.E., Stalla, G.K., Holsboer, F., Arzt, E., The Th1 and Th2 cytokines IFN-gamma and IL-4 antagonize the inhibition of monocyte IL-1 receptor antagonist by glucocorticoids: Involvement of IL-1 (1998) European Journal of Immunology, 28 (7), pp. 2075-2085. , DOI 10.1002/(SICI)1521-4141(199807)28:07<2075::AID-IMMU2075>3.0. CO;2-0
• Galon, J., Franchimont, D., Hiroi, N., Frey, G., Boettner, A., Ehrhart-Bornstein, M., O'Shea, J.J., Bornstein, S.R., Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells (2002) FASEB Journal, 16 (1), pp. 61-71. , DOI 10.1096/fj.01-0245com
• Laue, L., Kawai, S., Brandon, D.D., Brightwell, D., Barnes, K., Knazek, R.A., Loriaux, D.L., Chrousos, G.P., Receptor-mediated effects of glucocorticoids on inflammation: Enhancement of the inflammatory response with a glucocorticoid antagonist (1988) Journal of Steroid Biochemistry, 29 (6), pp. 591-598. , DOI 10.1016/0022-4731(88)90156-2
• Boumpas, D.T., Chrousos, G.P., Wilder, R.L., Cupps, T.R., Balow, J.E., Glucocorticoid therapy for immune-mediated diseases: Basic and clinical correlates (1993) Ann. Intern. Med., 119, pp. 1198-1208
• Giguere, V., Hollenberg, S.M., Rosenfeld, M.G., Evans, R.M., Functional domains of the human glucocorticoid receptor (1986) Cell, 46 (5), pp. 645-652
• Nissen, R.M., Yamamoto, K.R., The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain (2000) Genes Dev., 14, pp. 2314-2329
• Jonat, C., Rahmsdorf, H.J., Park, K.-K., Cato, A.C.B., Gebel, S., Ponta, H., Herrlich, P., Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone (1990) Cell, 62 (6), pp. 1189-1204. , DOI 10.1016/0092-8674(90)90395-U
• Yang-Yen, H.-F., Chambard, J.-C., Sun, Y.-L., Smeal, T., Schmidt, T.J., Drouin, J., Karin, M., Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction (1990) Cell, 62 (6), pp. 1205-1215. , DOI 10.1016/0092-8674(90)90396-V
• Schule, R., Rangarajan, P., Kliewer, S., Ransone, L.J., Bolado, J., Yang, N., Verma, I.M., Evans, R.M., Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor (1990) Cell, 62 (6), pp. 1217-1226. , DOI 10.1016/0092-8674(90)90397-W
• Caldenhoven, E., Liden, J., Wissink, S., Van De Stolpe, A., Raaijmakers, J., Koenderman, L., Okret, S., Van Der Saag, P.T., Negative cross-talk between RelA and the glucocorticoid receptor: A possible mechanism for the anti-inflammatory action of glucocorticoids (1995) Mol. Endocrinol., 9, pp. 401-412
• Biola, A., Andreau, K., David, M., Sturm, M., Haake, M., Bertoglio, J., Pallardy, M., The glucocorticoid receptor and STAT6 physically and functionally interact in T-lymphocytes (2000) FEBS Letters, 487 (2), pp. 229-233. , DOI 10.1016/S0014-5793(00)02297-3, PII S0014579300022973
• De Bosscher, K., Vanden Berghe, W., Haegeman, G., Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: Negative interference of activated glucocorticoid receptor with transcription factors (2000) Journal of Neuroimmunology, 109 (1), pp. 16-22. , DOI 10.1016/S0165-5728(00)00297-6, PII S0165572800002976
• De Bosscher, K., Vanden Berghe, W., Haegeman, G., The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: Molecular mechanisms for gene repression (2003) Endocrine Reviews, 24 (4), pp. 488-522. , DOI 10.1210/er.2002-0006
• Gottlicher, M., Heck, S., Herrlich, P., Transcriptional cross-talk, the second mode of steroid hormone receptor action (1998) Journal of Molecular Medicine, 76 (7), pp. 480-489. , DOI 10.1007/s001090050242
• Reichardt, H.M., Tuckermann, J.P., Gottlicher, M., Vujic, M., Weih, F., Angel, P., Herrlich, P., Schutz, G., Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor (2001) EMBO Journal, 20 (24), pp. 7168-7173. , DOI 10.1093/emboj/20.24.7168
• Scheinman, R.I., Gualberto, A., Jewell, C.M., Cidlowski, J.A., Baldwin Jr., A.S., Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors (1995) Mol. Cell. Biol., 15, pp. 943-953
• Adcock, I.M., Glucocorticoid-regulated transcription factors (2001) Pulm. Pharmacol. Ther., 14, pp. 211-219
• Ho, I.-C., Vorhees, P., Marin, N., Oakley, B.K., Tsai, S.-F., Orkin, S.H., Leiden, J.M., Human GATA-3: A lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene (1991) EMBO Journal, 10 (5), pp. 1187-1192
• Pandolfi, P.P., Roth, M.E., Karis, A., Leonard, M.W., Dzierzak, E., Grosveld, F.G., Engel, J.D., Lindenbaum, M.H., Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis (1995) Nat. Genet., 11, pp. 40-44
• Hendriks, R.W., Nawijn, M.C., Engel, J.D., Van Doorninck, H., Grosveld, F., Karis, A., Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus (1999) European Journal of Immunology, 29 (6), pp. 1912-1918. , DOI 10.1002/(SICI)1521-4141(199906)29:06<1912::AID-IMMU1912>3.0. CO;2-D
• Zheng, W.-P., Flavell, R.A., The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells (1997) Cell, 89 (4), pp. 587-596
• Zhang, D.-H., Cohn, L., Ray, P., Bottomly, K., Ray, A., Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene (1997) Journal of Biological Chemistry, 272 (34), pp. 21597-21603. , DOI 10.1074/jbc.272.34.21597
• Zhang, D.-H., Yang, L., Cohn, L., Parkyn, L., Homer, R., Ray, P., Ray, A., Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3 (1999) Immunity, 11 (4), pp. 473-482. , DOI 10.1016/S1074-7613(00)80122-3
• Hamid, Q., Azzawi, M., Ying, S., Moqbel, R., Wardlaw, A.J., Corrigan, C.J., Bradley, B., Jeffery, P.K., Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma (1991) J. Clin. Invest., 87, pp. 1541-1546
• Zhang, D.-H., Yang, L., Ray, A., Cutting edge: Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3 (1998) Journal of Immunology, 161 (8), pp. 3817-3821
• Ouyang, W., Ranganath, S.H., Weindel, K., Bhattacharya, D., Murphy, T.L., Sha, W.C., Murphy, K.M., Inhibition of Th1 development mediated by GATA-3 through an IL-4- Independent mechanism (1998) Immunity, 9 (5), pp. 745-755
• Ferber, I.A., Lee, H.-J., Zonin, F., Heath, V., Mui, A., Arai, N., O'Garra, A., GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels (1999) Clinical Immunology, 91 (2), pp. 134-144. , DOI 10.1006/clim.1999.4718
• Ouyang, W., Lohning, M., Gao, Z., Assenmacher, M., Ranganath, S., Radbruch, A., Murphy, K.M., Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment (2000) Immunity, 12 (1), pp. 27-37
• Chen, C.H., Zhang, D.H., LaPorte, J.M., Ray, A., Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: Phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression (2000) J. Immunol., 165, pp. 5597-5605
• Maneechotesuwan, K., Xin, Y., Ito, K., Jazrawi, E., Lee, K.-Y., Usmani, O.S., Barnes, P.J., Adcock, I.M., Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3 (2007) Journal of Immunology, 178 (4), pp. 2491-2498
• Klein-Hessling, S., Jha, M.K., Santner-Nanan, B., Berberich-Siebelt, F., Baumruker, T., Schimpl, A., Serfling, E., Protein kinase a regulates GATA-3-dependent activation of IL-5 gene expression in Th2 cells (2003) Journal of Immunology, 170 (6), pp. 2956-2961
• Furst, R., Schroeder, T., Eilken, H.M., Bubik, M.F., Kiemer, A.K., Zahler, S., Vollmar, A.M., MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium (2007) FASEB Journal, 21 (1), pp. 74-80. , http://www.fasebj.org/cgi/reprint/21/1/74, DOI 10.1096/fj.06-6752com
• Lasa, M., Abraham, S.M., Boucheron, C., Saklatvala, J., Clark, A.R., Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38 (2002) Molecular and Cellular Biology, 22 (22), pp. 7802-7811. , DOI 10.1128/MCB.22.22.7802-7811.2002
• Szabo, S.J., Kim, S.T., Costa, G.L., Zhang, X., Fathman, C.G., Glimcher, L.H., A novel transcription factor, T-bet, directs Th1 lineage commitment (2000) Cell, 100, pp. 655-669
• Liberman, A.C., Refojo, D., Druker, J., Toscano, M., Rein, T., Holsboer, F., Arzt, E., The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction (2007) FASEB Journal, 21 (4), pp. 1177-1188. , http://www.fasebj.org/cgi/reprint/21/4/1177, DOI 10.1096/fj.06-7452com
• Raiden, S., Polack, E., Nahmod, V., Labeur, M., Holsboer, F., Arzt, E., TRH receptor on immune cells: In vitro and in vivo stimulation of human lymphocyte and rat splenocyte DNA synthesis by TRH (1995) J. Clin. Immunol., 15, pp. 242-249
• Siegel, M.D., Zhang, D.H., Ray, P., Ray, A., Activation of the interleukin-5 promoter by cAMP in murine EL4 cells requires the GATA-3 and CLE0 elements (1995) J. Biol. Chem., 270, pp. 24548-24555
• Hwang, E.S., Choi, A., Ho, I.-C., Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1 (2002) Journal of Immunology, 169 (1), pp. 248-253
• Lee, H.J., Takemoto, N., Kurata, H., Kamogawa, Y., Miyatake, S., O'Garra, A., Arai, N., GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells (2000) Journal of Experimental Medicine, 192 (1), pp. 105-115. , DOI 10.1084/jem.192.1.105
• Lee, H.J., Masuda, E.S., Arai, N., Arai, K., Yokota, T., Definition of cis-regulatory elements of the mouse interleukin-5 gene promoter. Involvement of nuclear factor of activated T cell-related factors in interleukin-5 expression (1995) J. Biol. Chem., 270, pp. 17541-17550
• Kovalovsky, D., Refojo, D., Liberman, A.C., Hochbaum, D., Pereda, M.P., Coso, O.A., Stalla, G.K., Arzt, E., Activation and induction of Nur77/Nurr1 in corticotrophs by CRH/cAMP: Involvement of calcium, protein kinase a, and MAPK pathways (2002) Molecular Endocrinology, 16 (7), pp. 1638-1651. , DOI 10.1210/me.16.7.1638
• Hyun Jun, L., Koyano-Nakagawa, N., Naito, Y., Nishida, J., Arai, N., Arai-, K.I., Yokota, T., CAMP activates the IL-5 promoter synergistically with phorbol ester through the signaling pathway involving protein kinase a in mouse thymoma line EL-4 (1993) Journal of Immunology, 151 (11), pp. 6135-6142
• Rupprecht, R., Arriza, J.L., Spengler, D., Reul, J.M.H.M., Evans, R.M., Holsboer, F., Damm, K., Transactivation and synergistic properties of the mineralocorticoid receptor: Relationship to the glucocorticoid receptor (1993) Molecular Endocrinology, 7 (4), pp. 597-603. , DOI 10.1210/me.7.4.597
• Tanos, T., Marinissen, M.J., Leskow, F.C., Hochbaum, D., Martinetto, H., Gutkind, J.S., Coso, O.A., Phosphorylation of c-Fos by members of the p38 MAPK family: Role in the AP-1 response to UV light (2005) Journal of Biological Chemistry, 280 (19), pp. 18842-18852. , DOI 10.1074/jbc.M500620200
• Paez-Pereda, M., Giacomini, D., Refojo, D., Nagashima, A.C., Hopfner, U., Grubler, Y., Chervin, A., Arzt, E., Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk (2003) Proceedings of the National Academy of Sciences of the United States of America, 100 (3), pp. 1034-1039. , DOI 10.1073/pnas.0237312100
• Costas, M., Trapp, T., Pereda, M.P., Sauer, J., Rupprecht, R., Nahmod, V.E., Reul, J.M.H.M., Arzt, E., Molecular and functional evidence for in vitro cytokine enhancement of human and murine target cell sensitivity to glucocorticoids: TNF-alpha priming increases glucocorticoid inhibition of TNF-alpha-induced cytotoxicity/apoptosis (1996) Journal of Clinical Investigation, 98 (6), pp. 1409-1416
• Mori, A., Kaminuma, O., Suko, M., Inoue, S., Ohmura, T., Hoshino, A., Asakura, Y., Okudaira, H., Two distinct pathways of interleukin-5 synthesis in allergen-specific human T-cell clones are suppressed by glucocorticoids (1997) Blood, 89 (8), pp. 2891-2900
• Jee, Y.-K., Gilmour, J., Kelly, A., Bowen, H., Richards, D., Soh, C., Smith, P., Lavender, P., Repression of Interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment (2005) Journal of Biological Chemistry, 280 (24), pp. 23243-23250. , DOI 10.1074/jbc.M503659200
• Quan, A., McCall, M.N., Sewell, W.A., Dexamethasone inhibits the binding of nuclear factors to the IL-5 promoter in human CD4 T cells (2001) J. Allergy. Clin. Immunol., 108, pp. 340-348
• Caelles, C., Gonzalez-Sancho, J.M., Munoz, A., Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway (1997) Genes and Development, 11 (24), pp. 3351-3364
• Betz, M., Fox, B.S., Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines (1991) J. Immunol., 146, pp. 108-113
• Pelaia, G., Cuda, G., Vatrella, A., Grembiale, R.D., De Sarro, G., Maselli, R., Costanzo, F.S., Marsico, S.A., Effects of glucocorticoids on activation of c-jun N-terminal, extracellular signal-regulated, and p38 MAP kinases in human pulmonary endothelial cells (2001) Biochemical Pharmacology, 62 (12), pp. 1719-1724. , DOI 10.1016/S0006-2952(01)00791-2, PII S0006295201007912
• Lasa, M., Brook, M., Saklatvala, J., Clark, A.R., Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38 (2001) Molecular and Cellular Biology, 21 (3), pp. 771-780. , DOI 10.1128/MCB.21.3.771-780.2001
• Arthur, J.S., Cohen, P., MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells (2000) FEBS Lett., 482, pp. 44-48
• Beck, I.M., Vanden Berghe, W., Vermeulen, L., Bougarne, N., Vander Cruyssen, B., Haegeman, G., De Bosscher, K., Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition (2008) EMBO J., 27, pp. 1682-1693
• Sakai, D.D., Helms, S., Carlstedt-Duke, J., Gustafsson, J.A., Rottman, F.M., Yamamoto, K.R., Hormone-mediated repression: A negative glucocorticoid response element from the bovine prolactin gene (1988) Genes Dev., 2, pp. 1144-1154
• Novac, N., Baus, D., Dostert, A., Heinzel, T., Competition between glucocorticoid receptor and NFkappaB for control of the human FasL promoter (2006) FASEB Journal, 20 (8), pp. 1074-1081. , http://www.fasebj.org/cgi/reprint/20/8/1074, DOI 10.1096/fj.05-5457com
• Stranick, K.S., Zambas, D.N., Uss, A.S., Egan, R.W., Billah, M.M., Umland, S.P., Identification of transcription factor binding sites important in the regulation of the human interleukin-5 gene (1997) Journal of Biological Chemistry, 272 (26), pp. 16453-16465. , DOI 10.1074/jbc.272.26.16453
• Cho, J.Y., Grigura, V., Murphy, T.L., Murphy, K., Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-gamma promoter (2003) International Immunology, 15 (10), pp. 1149-1160. , DOI 10.1093/intimm/dxg113
• Hwang, E.S., Hong, J.H., Glimcher, L.H., IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508 (2005) J. Exp. Med., 202, pp. 1289-1300
• Miyaura, H., Iwata, M., Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids (2002) Journal of Immunology, 168 (3), pp. 1087-1094
• Ramirez, F., Glucocorticoids induce a Th2 response in vitro (1998) Dev. Immunol., 6, pp. 233-243
• Daynes, R.A., Araneo, B.A., Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4 (1989) Eur. J. Immunol., 19, pp. 2319-2325
• Brinkmann, V., Kristofic, C., Regulation by corticosteroids of Th1 and Th2 cytokine production in human CD4+ effector T cells generated from CD45RO- and CD45RO+ subsets (1995) J. Immunol., 155, pp. 3322-3328

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