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gamma interferon

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"Aesculus hippocastanum L. seed extract shows virucidal and antiviral activities against respiratory syncytial virus (RSV) and reduces lung inflammation in vivo" (2019) Salinas, F.M.;Vázquez, L.;Gentilini, M.V. (...)Bueno, C.A. Antiviral Research. 164:1-11

"Evaluation of the immune response against Trypanosoma cruzi cytosolic tryparedoxin peroxidase in human natural infection" (2018) Girard, M.C.;Acevedo, G.R.;López, L. (...)Gómez, K.A. Immunology. 155(3):367-378

"IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity" (2018) Song, M.;Sandoval, T.A.;Chae, C.-S. (...)Cubillos-Ruiz, J.R. Nature. 562(7727):423-428

"Leptin action in normal and pathological pregnancies" (2018) Pérez-Pérez, A.;Toro, A.;Vilariño-García, T. (...)Sánchez-Margalet, V. Journal of Cellular and Molecular Medicine. 22(2):716-727

"Elevated cyclic AMP inhibits mycobacterium tuberculosis-stimulated T-cell IFN-γ secretion through type I protein kinase A" (2018) Chung, Y.-T.;Pasquinelli, V.;Jurado, J.O. (...)Samten, B. Journal of Infectious Diseases. 217(11):1821-1831

"Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j" (2018) Nuñez, S.Y.;Ziblat, A.;Secchiari, F. (...)Zwirner, N.W. Journal of Immunology. 200(3):1008-1015

"Interleukin (IL)-23 stimulates IFN-γ secretion by CD56bright natural killer cells and enhances IL-18-driven dendritic cells activation" (2018) Ziblat, A.;Nuñez, S.Y.;Iraolagoitia, X.L.R. (...)Zwirner, N.W. Frontiers in Immunology. 8(JAN)

"Adjuvants in cutaneous melanoma patients: Long term antitumor immunity and short term release of acute inflammatory reactants" (2018) Pampena, M.B.;Cartar, H.C.;Cueto, G.R. (...)Mordoh, J. Frontiers in Immunology. 9(NOV)

"The IFNG rs1861494 single nucleotide polymorphism is associated with protection against tuberculosis disease in Argentina" (2018) Rolandelli, A.;Pellegrini, J.M.;Amiano, N.O. (...)García, V.E. Genes. 9(1)

"Primary immunodeficiencies unravel the role of IL-2/CD25/STAT5b in human natural killer cell maturation" (2018) Caldirola, M.S.;Broggi, M.G.R.;Gaillard, M.I. (...)Zwirner, N.W. Frontiers in Immunology. 9(JUN)

"Untangling Galectin-Driven Regulatory Circuits in Autoimmune Inflammation" (2018) Toscano, M.A.;Martínez Allo, V.C.;Cutine, A.M. (...)Mariño, K.V. Trends in Molecular Medicine. 24(4):348-363

"A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity" (2017) Noya, V.;Brossard, N.;Rodríguez, E. (...)Freire, T. Scientific Reports. 7

"Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: The case of IL-27" (2017) Zwirner, N.W.; Ziblat, A. Frontiers in Immunology. 8(JAN)

"Immunization with inactivated antigens of Neospora caninum induces toll-like receptors 3, 7, 8 and 9 in maternal-fetal interface of infected pregnant heifers" (2017) Marin, M.S.;Hecker, Y.P.;Quintana, S. (...)Odeón, A.C. Veterinary Parasitology. 243:12-17

"Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses" (2017) Hernández Del Pino, R.E.;Pellegrini, J.M.;Rovetta, A.I. (...)Garciá, V.E. Immunology and Cell Biology. 95(8):716-728

"The IL-17A rs2275913 single nucleotide polymorphism is associated with protection to tuberculosis but related to higher disease severity in Argentina" (2017) Rolandelli, A.;Del Pino, R.E.H.;Pellegrini, J.M. (...)García, V.E. Scientific Reports. 7

"The kinase inhibitors R406 and GS-9973 impair T cell functions and macrophage-mediated anti-tumor activity of rituximab in chronic lymphocytic leukemia patients" (2017) Colado, A.;Almejún, M.B.;Podaza, E. (...)Borge, M. Cancer Immunology, Immunotherapy. 66(4):461-473

"Galectin-1-driven tolerogenic programs aggravate yersinia enterocolitica infection by repressing antibacterial immunity" (2017) Davicino, R.C.;Méndez-Huergo, S.P.;Eliçabe, R.J. (...)Rabinovich, G.A. Journal of Immunology. 199(4):1382-1392

"IL17A augments autophagy in Mycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease" (2017) Tateosian, N.L.;Pellegrini, J.M.;Amiano, N.O. (...)García, V.E. Autophagy. 13(7):1191-1204

"Driving CARs into Sweet Roads: Targeting Glycosylated Antigens in Cancer" (2016) Blidner, A.G.; Mariño, K.V.; Rabinovich, G.A. Immunity. 44(6):1248-1250

"The thyroid status reprograms T cell lymphoma growth and modulates immune cell frequencies" (2016) Sterle, H.A.;Barreiro Arcos, M.L.;Valli, E. (...)Cremaschi, G.A. Journal of Molecular Medicine. 94(4):417-429

"Lack of galectin-3 increases Jagged1/Notch activation in bone marrow-derived dendritic cells and promotes dysregulation of T helper cell polarization" (2016) Fermino, M.L.;Dylon, L.S.D.;Cecílio, N.T. (...)Bernardes, E.S. Molecular Immunology. 76:22-34

"Expression and functional role of α7 nicotinic receptor in human cytokine-stimulated natural killer (NK) cells" (2016) Zanetti, S.R.;Ziblat, A.;Torres, N.I. (...)Bouzat, C. Journal of Biological Chemistry. 291(32):16541-16552

"Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling" (2016) Sampson, J.F.;Suryawanshi, A.;Chen, W.-S. (...)Panjwani, N. Immunology and Cell Biology. 94(2):213-219

"Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via TLR9 and MyD88 Signaling" (2016) Puttur, F.;Francozo, M.;Solmaz, G. (...)Sparwasser, T. Cell Reports. 17(4):1113-1127

"NK cells restrain spontaneous antitumor CD8+ T cell priming through pd-1/pd-l1 interactions with dendritic cells" (2016) Raffo Iraolagoitia, X.L.;Spallanzani, R.G.;Torres, N.I. (...)Fuertes, M.B. Journal of Immunology. 197(3):953-961

"The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity" (2016) Alamino, V.A.; Montesinos, M.M.; Rabinovich, G.A.; Pellizas, C.G. OncoImmunology. 5(1)

"Deletion of A44L, A46R and C12L vaccinia virus genes from the MVA genome improved the vector immunogenicity by modifying the innate immune response generating enhanced and optimized specific T-cell responses" (2016) Holgado, M.P.;Falivene, J.;Maeto, C. (...)Gherardi, M.M. Viruses. 8(5)

"VIP boosts regulatory T cell induction by trophoblast cells in an in vitro model of trophoblast–maternal leukocyte interaction" (2015) Fraccaroli, L.;Grasso, E.;Hauk, V. (...)Ramhorst, R. Journal of Leukocyte Biology. 98(1):49-58

"Trypanosoma cruzi infection imparts a regulatory program in dendritic cells and T cells via galectin-1-dependent mechanisms" (2015) Poncini, C.V.;Ilarregui, J.M.;Batalla, E.I. (...)Rabinovich, G.A. Journal of Immunology. 195(7):3311-3324

"Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells" (2015) Díaz, P.R.;Mucci, J.;Meira, M.A. (...)Campetella, O. Infection and Immunity. 83(5):2099-2108

"IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness" (2015) Ziblat, A.;Domaica, C.I.;Spallanzani, R.G. (...)Zwirner, N.W. European Journal of Immunology. 45(1):192-202

"A Mycobacterium tuberculosis Dormancy Antigen Differentiates Latently Infected Bacillus Calmette-Guérin-vaccinated Individuals" (2015) Peña, D.;Rovetta, A.I.;Hernández Del Pino, R.E. (...)García, V.E. EBioMedicine. 2(8):884-890

"Antitumor responses stimulated by dendritic cells are improved by triiodothyronine binding to the thyroid hormone receptor β" (2015) Alamino, V.A.;Mascanfroni, I.D.;Montesinos, M.M. (...)Pellizas, C.G. Cancer Research. 75(7):1265-1274

"Regulatory dendritic cells restrain NK cell IFN-γ production through mechanisms involving NKp46, IL-10, and MHC class I-specific inhibitory receptors" (2015) Spallanzani, R.G.;Torres, N.I.;Avila, D.E. (...)Zwirner, N.W. Journal of Immunology. 195(5):2141-2148

"Effect of the potent antiviral 1-cinnamoyl-3,11-dihydroxymeliacarpin on cytokine production by murine macrophages stimulated with HSV-2" (2014) Petrera, E.; Coto, C.E. Phytotherapy Research. 28(1):104-109

"IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis" (2014) Rovetta, A.I.;Peña, D.;Hernández Del Pino, R.E. (...)García, V.E. Autophagy. 10(12):2109-2121

"Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes" (2014) Castro, C.N.;Barcala Tabarrozzi, A.E.;Winnewisser, J. (...)Perone, M.J. Clinical and Experimental Immunology. 177(1):149-160

"Antiviral Action of Synthetic Stigmasterol Derivatives on Herpes Simplex Virus Replication in Nervous Cells in Vitro" (2014) Petrera, E.; Níttolo, A.G.; Alché, L.E. BioMed Research International. 2014

"Bayesian Approach to Model CD137 Signaling in Human M. tuberculosis In Vitro Responses" (2013) Fernández Do Porto, D.A.;Auzmendi, J.;Peña, D. (...)Moffatt, L. PLoS ONE. 8(2)

"Galectin-3 negatively regulates the frequency and function of CD4 + CD25 + Foxp3 + regulatory T cells and influences the course of Leishmania major infection" (2013) Fermino, M.L.;Dias, F.C.;Lopes, C.D. (...)Bernardes, E.S. European Journal of Immunology. 43(7):1806-1817

"Peripheral and central inflammation in autism spectrum disorders" (2013) Depino, A.M. Molecular and Cellular Neuroscience. 53:69-76

"Parasite infections in multiple sclerosis modulate immune responses through a retinoic acid-dependent pathway" (2013) Correale, J.; Farez, M.F. Journal of Immunology. 191(7):3827-3837

"Phosphorylation of mitogen-activated protein kinases contributes to interferon γ production in response to mycobacterium tuberculosis" (2013) Pasquinelli, V.;Rovetta, A.I.;Alvarez, I.B. (...)García, V.E. Journal of Infectious Diseases. 207(2):340-350

"CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis" (2012) Fernández Do Porto, D.A.;Jurado, J.O.;Pasquinelli, V. (...)García, V.E. Immunology and Cell Biology. 90(4):449-456

"Compound a, a dissociated glucocorticoid receptor modulator, inhibits t-bet (th1) and induces gata-3 (th2) activity in immune cells" (2012) Liberman, A.C.;Antunica-Noguerol, M.;Ferraz-de-Paula, V. (...)Arzt, E. PLoS ONE. 7(4)

"Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments" (2012) Soldati, R.;Berger, E.;Zenclussen, A.C. (...)Fest, S. International Journal of Cancer. 131(5):1131-1141

"Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development" (2012) Domaica, C.I.;Fuertes, M.B.;Uriarte, I. (...)Zwirner, N.W. PLoS ONE. 7(12)

"Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration" (2012) Starossom, S.;Mascanfroni, I.;Imitola, J. (...)Rabinovich, G. Immunity. 37(2):249-263

"Oral administration of fluoxetine alters the proliferation/apoptosis balance of lymphoma cells and up-regulates T cell immunity in tumor-bearing mice" (2011) Frick, L.R.;Rapanelli, M.;Arcos, M.L.B. (...)Genaro, A.M. European Journal of Pharmacology. 659(2-3):265-272

"Serine leucocyte proteinase inhibitor-treated monocyte inhibits human CD4+ lymphocyte proliferation" (2011) Guerrieri, D.;Tateosian, N.L.;Maffía, P.C. (...)Chuluyan, H.E. Immunology. 133(4):434-441

"When galectins recognize glycans: From biochemistry to physiology and back again" (2011) Di Lella, S.;Sundblad, V.;Cerliani, J.P. (...)Rabinovich, G.A. Biochemistry. 50(37):7842-7857

"Modulation of macrophage inflammatory profile in pregnant nonobese diabetic (NOD) mice" (2011) Larocca, L.;Hauk, V.;Calafat, M. (...)Leirós, C.P. Molecular and Cellular Endocrinology. 333(2):112-118

"Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan" (2011) Mateu, C.G.;Recalde, M.P.;Artuso, M.C. (...)Carlucci, M.J. Sexually Transmitted Diseases. 38(6):555-561

"Gender differences in 1,25 dihydroxyvitamin D3 immunomodulatory effects in multiple sclerosis patients and healthy subjects" (2010) Correale, J.; Ysrraelit, M.C.; Gaitan, M.I. Journal of Immunology. 185(8):4948-4958

"Interferon-γ Inhibits Metalloproteinase Activity and Cytotrophoblast Cell Migration" (2010) Fontana, V.A.; Sanchez, M.; Cebral, E.; Calvo, J.C. American Journal of Reproductive Immunology. 64(1):20-26

"Novel medical therapies for pituitary tumors" (2010) Theodoropoulou, M.;Labeur, M.;Paez Pereda, M. (...)Stalla, G.K. Frontiers of Hormone Research. 38:158-164

"Tolerogenic dendritic cells in the control of autoimmune neuroinflammation: An emerging role of protein-glycan interactions" (2010) Ilarregui, J.M.; Rabinovich, G.A. NeuroImmunoModulation. 17(3):157-160

"IFN-γ production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB" (2009) Pasquinelli, V.;Townsend, J.C.;Jurado, J.O. (...)García, V.E. Journal of Infectious Diseases. 199(5):661-665

"A potential tolerogenic immune mechanism in a trophoblast cell line through the activation of chemokine-induced T cell death and regulatory T cell modulation" (2009) Fraccaroli, L.;Alfieri, J.;Larocca, L. (...)Ramhorst, R. Human Reproduction. 24(1):166-175

"Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas" (2009) Labeur, M.; Paez-Pereda, M.; Arzt, E.; Stalla, G.K. Reviews in Endocrine and Metabolic Disorders. 10(2):103-109

"Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms" (2009) Frick, L.R.; Rapanelli, M.; Cremaschi, G.A.; Genaro, A.M. Brain, Behavior, and Immunity. 23(1):36-40

"Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10" (2009) Ilarregui, J.M.;Croci, D.O.;Bianco, G.A. (...)Rabinovich, G.A. Nature Immunology. 10(9):981-991

"Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection" (2009) Petrera, E.; Coto, C.E. Phytotherapy Research. 23(12):1771-1777

"Chronic restraint stress impairs T-cell immunity and promotes tumor progression in mice" (2009) Frick, L.R.;Barreiro Arcos, M.L.;Rapanelli, M. (...)Cremaschi, G.A. Stress. 12(2):134-143

"Dehydroepiandrosterone and metformin modulate progesterone-induced blocking factor (PIBF), cyclooxygenase 2 (COX2) and cytokines in early pregnant mice" (2008) Luchetti, C.G.;Mikó, E.;Szekeres-Bartho, J. (...)Motta, A.B. Journal of Steroid Biochemistry and Molecular Biology. 111(3-5):200-207

"Interferon-γ inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway" (2008) Labeur, M.;Refojo, D.;Wölfel, B. (...)Stalla, G.K. Journal of Endocrinology. 199(2):177-189

"Control of dendritic cell maturation and function by triiodothyronine" (2008) Mascanfroni, I.;Montesinos, M.D.M.;Susperreguy, S. (...)Pellizas, C.G. FASEB Journal. 22(4):1032-1042

"Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis" (2008) Jurado, J.O.;Alvarez, I.B.;Pasquinelli, V. (...)García, V.E. Journal of Immunology. 181(1):116-125

"NOD mice exocrinopathy: Towards a neuroimmune link" (2007) Calafat, M.; Larocca, L.; Roca, V.; Pérez Leirós, C. NeuroImmunoModulation. 14(3-4):175-181

"Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes" (2007) von Euw, E.M.;Barrio, M.M.;Furman, D. (...)Mordoh, J. Journal of Translational Medicine. 5

"Integrating the universe of regulatory cells in cancer. A major hurdle for successful immunotherapy " (2007) Ilarregui, J.M.;Croci, D.O.;Toscano, M.A. (...)Rabinovich, G.A. Medicina. 67(SUPPL 2):25-31

"The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction" (2007) Liberman, A.C.;Refojo, D.;Druker, J. (...)Arzt, E. FASEB Journal. 21(4):1177-1188

"Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice" (2006) Perone, M.J.;Bertera, S.;Tawadrous, Z.S. (...)Morelli, A.E. Journal of Immunology. 177(8):5278-5289

"Reduced nitric oxide synthase and cyclo-oxygenase activity in the uterus of non-obese diabetic mice" (2006) Roca, V.;Larocca, L.;Calafat, M. (...)Leirós, C.P. Reproduction. 132(6):931-938

"PyNTTTTGT prototype oligonucleotide IMT504 is a potent adjuvant for the recombinant Hepatitis B vaccine that enhances the Th1 response" (2005) Elias, F.;Flo, J.;Rodriguez, J.M. (...)Montaner, A. Vaccine. 23(27):3597-3603

"Exogenous interferon-γ alters murine inner cell mass and trophoblast development. Effect on the expression of ErbB1, ErbB4 and heparan sulfate proteoglycan (perlecan)" (2004) Fontana, V.;Choren, V.;Vauthay, L. (...)Cameo, M. Reproduction. 128(6):717-725

"Immunostimulatory effects of plasmid DNA and synthetic oligodeoxynucleotides" (2003) Zelenay, S.; Elías, F.; Fló, J. European Journal of Immunology. 33(5):1382-1392

"Time course of T-cell responses to MOG and MBP in patients with clinically isolated syndromes" (2003) Correale, J.; Bassani Molinas, M.D.L.M. Journal of Neuroimmunology. 136(1-2):162-171

"Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used" (2003) Velikovsky, C.A.;Goldbaum, F.A.;Cassataro, J. (...)Giambartolomei, G.H. Infection and Immunity. 71(10):5750-5755

"Cytokine Signaling/Transcription Factor Cross-Talk in T Cell Activation and Th1-Th2 Differentiation" (2003) Liberman, A.C.; Refojo, D.; Arzt, E. Archivum Immunologiae et Therapiae Experimentalis. 51(6):351-365

"Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma" (2003) Goldszmid, R.S.;Idoyaga, J.;Bravo, A.I. (...)Wainstok, R. Journal of Immunology. 171(11):5940-5947

"Co-immunization with plasmids coding the full length and a soluble form of glycoprotein D of HSV-2 induces protective cellular and humoral immune response in mice" (2003) Fló, J. Vaccine. 21(11-12):1239-1245

"Modulation of the immune response mediated by oral transgene administration of IL-10" (2002) Elías, F.; Fló, J. Cellular Immunology. 216(1-2):73-81

"Molecular mechanisms and Th1/Th2 pathways in corticosteroid regulation of cytokine production" (2000) Kovalovsky, D.; Refojo, D.; Holsboer, F.; Arzt, E. Journal of Neuroimmunology. 109(1):23-29

"The Th1 and Th2 cytokines IFN-γ and IL-4 antagonize the inhibition of monocyte IL-1 receptor antagonist by glucocorticoids: Involvement of IL-1" (1998) Kovalovsky, D.;Pereda, M.P.;Sauer, J. (...)Arzt, E. European Journal of Immunology. 28(7):2075-2085

"Anti-tumor activity of cytokines against opportunistic vascular tumors in mice" (1996) Dong, Q.G.;Graziani, A.;Garlanda, C. (...)Bussolino, F. International Journal of Cancer. 65(5):700-708

"Low lymphocyte interferon-gamma production and variable proliferative response in anorexia nervosa patients" (1993) Polack, E.;Nahmod, V.E.;Emeric-Sauval, E. (...)Arzt, E. Journal of Clinical Immunology. 13(6):445-451

"Superinduction of Mitogen-Stimulated Interferon-γ Production and Other Lymphokines by Sendai Virus" (1993) Costas, M.A.;Mella, D.;Criscuolo, M. (...)Arzt, E. Journal of Interferon Research. 13(6):407-412