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Referencias:

• Atkinson, M.A., Maclaren, N.K., The pathogenesis of insulin-dependent diabetes mellitus (1994) N. Engl. J. Med., 331, pp. 1428-1436
• Perillo, N.L., Marcus, M.E., Baum, L.G., Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death (1998) J. Mol. Med., 76, pp. 402-412
• Rabinovich, G.A., Baum, L.G., Tinari, N., Paganelli, R., Natoli, C., Liu, F.T., Iacobelli, S., Galectins and their ligands: Amplifiers, silencers or turners of the inflammatory response (2002) Trends Immunol., 23, pp. 313-320
• Perillo, N.L., Pace, K.E., Seilhamer, J.J., Baum, L.G., Apoptosis of T cells mediated by galectin-1 (1995) Nature, 378, pp. 736-739
• Perillo, N.L., Uittenbogaart, C.H., Nguyen, J.T., Baum, L.G., Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes (1997) J. Exp. Med., 185, pp. 1851-1858
• Rabinovich, G.A., Daly, G., Dreja, H., Tailor, H., Riera, C.M., Hirabayashi, J., Chernajovsky, Y., Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis (1999) J. Exp. Med., 190, pp. 385-398
• Poirier, F., Timmons, P.M., Chan, C.-T.J., Guenet, J.-L., Rigby, P.W.J., Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development (1992) Development, 115, pp. 143-155
• Dettin, L., Rubinstein, N., Aoki, A., Rabinovich, G.A., Maldonado, C.A., Regulated expression and ultrastructural localization of Galectin-1, a proapoptotic β-galactoside-binding lectin, during spermatogenesis in rat testis (2002) Biol. Reprod., 68, pp. 51-59
• Joubert, R., Kuchler, S., Zanetta, J.P., Bladier, D., Avellana-Adalid, V., Caron, M., Doinel, C., Vincendon, G., Immunohistochemical localization of a β-galactoside-binding lectin in the rat central nervous system. I. Light- and electron-microscopical studies on developing cerebral cortex and corpus callosum (1989) Dev. Neurosci., 11, pp. 397-413
• Rubinstein, N., Alvarez, M., Zwirner, N.W., Toscano, M.A., Ilarregui, J.M., Bravo, A., Mordoh, J., Rabinovich, G.A., Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection: A potential mechanism of tumor-immune privilege (2004) Cancer Cell, 5, pp. 241-251
• McHugh, R.S., Whitters, M.J., Piccirillo, C.A., Young, D.A., Shevach, E.M., Collins, M., Byrne, M.C., CD4+CD25+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor (2002) Immunity, 16, pp. 311-323
• Offner, H., Celnik, B., Bringman, T.S., Casentini-Borocz, D., Nedwin, G.E., Vandenbark, A.A., Recombinant human β-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis (1990) J. Neuroimmunol., 28, pp. 177-184
• Santucci, L., Fiorucci, S., Rubinstein, N., Mencarelli, A., Palazzetti, B., Federici, B., Rabinovich, G.A., Morelli, A., Galectin-1 suppresses experimental colitis in mice (2003) Gastroenterology, 24, pp. 1381-1394
• Banchereau, J., Steinman, R.M., Dendritic cells and the control of immunity (1998) Nature, 392, pp. 245-252
• Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y.J., Pulendran, B., Palucka, K., Immunobiology of dendritic cells (2000) Annu. Rev. Immunol., 18, pp. 767-811
• Ludewig, B., Odermatt, B., Landmann, S., Hengartner, H., Zinkernagel, R.M., Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue (1998) J. Exp. Med., 188, pp. 1493-1501
• Jonuleit, H., Schmitt, E., Steinbrink, K., Enk, A.H., Dendritic cells as a tool to induce anergic and regulatory T cells (2001) Trends Immunol., 22, pp. 394-400
• Steinman, R.M., Hawiger, D., Nussenzweig, M.C., Tolerogenic dendritic cells (2003) Annu. Rev. Immunol., 21, pp. 685-711
• Thiessen, S., Serra, P., Amrani, A., Verdaguer, J., Santamaria, P., T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes (2002) Diabetes, 51, pp. 325-338
• Morelli, A.E., Thomson, A.W., Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction (2003) Immunol. Rev., 196, pp. 125-146
• Hackstein, H., Thomson, A.W., Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs (2004) Nat. Rev. Immunol., 4, pp. 24-34
• Feili-Hariri, M., Xin, D., Alber, S.M., Watkins, S.C., Salter, R.D., Morel, P.A., Immunotherapy of NOD mice with bone marrow-derived dendritic cells (1999) Diabetes, 48, pp. 2300-2308
• Machen, J., Harnaha, J., Lakomy, R., Styche, A., Trucco, M., Giannoukakis, N., Antisense oligonucleotides down-regulate costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells (2004) J. Immunol., 173, pp. 4331-4341
• Santucci, L., Fiorucci, S., Cammilleri, F., Servillo, G., Federici, B., Morelli, A., Galectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in mice (2000) Hepatology, 31, pp. 399-406
• Baum, L.G., Blackall, D.P., Arias-Magallano, S., Nanigian, D., Uh, S.Y., Browne, J.M., Hoffmann, D., Baldwin, G.C., Amelioration of graft versus host disease by galectin-1 (2003) Clin. Immunol., 109, pp. 295-307
• Pace, K.E., Hahn, H.P., Baum, L.G., Preparation of recombinant human galetin-1 and use in T cell assays (2003) Methods Enzymol., 363, pp. 499-518
• Morelli, A.E., Zahorchak, A.F., Larregina, A.T., Colvin, B.L., Logar, A.J., Takayama, T., Falo, L.D., Thomson, A.W., Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation (2001) Blood, 98, pp. 1512-1523
• Katz, J.D., Wang, B., Haskins, K., Benoist, C., Mathis, D., Following a diabetogenic T cell from genesis through pathogenesis (1993) Cell, 74, pp. 1089-1100
• Yoshida, K., Martin, T., Yamamoto, K., Dobbs, C., Munz, C., Kamikawaji, N., Nakano, N., Kikutani, H., Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones (2002) Int. Immunol., 12, pp. 1439-1447
• Piganelli, J.D., Flores, S.C., Cruz, C., Koepp, J., Batinic-Haberle, I., Crapo, J., Day, B., Haskins, K., A metalloprophyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone (2002) Diabetes, 51, pp. 347-355
• Kurrer, M.O., Pakala, S., Hanson, H.L., Katz, J.D., β cell apoptosis in T cell-mediated autoimmune diabetes (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 213-218
• Christianson, S.W., Shultz, L.D., Leiter, E.H., Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice: Relative contributions of CD4+ and CD8+ T cells from diabetic versus prediabetic NOD.NOD-Thy-1a donors (1993) Diabetes, 42, pp. 44-55
• Rohane, P.W., Shimada, A., Kim, D.T., Edwards, C.T., Charlton, B., Shultz, L.D., Fathman, G., Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice (1995) Diabetes, 44, pp. 550-554
• Bertera, S., Crawford, M.L., Alexander, A.M., Papworth, G.D., Watkins, S.C., Robbins, P.D., Trucco, M., Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes (2003) Diabetes, 52, pp. 387-393
• Matarese, G., Sanna, V., Lechler, R.I., Sarvetnick, N., Fontana, S., Zappacosta, S., La Cava, A., Leptin accelerates autoimmune diabetes in female NOD mice (2002) Diabetes, 51, pp. 1356-1361
• Perone, M.J., Larregina, A.T., Shufesky, W.J., Papworth, G.D., Sullivan, M.L.G., Zahorchak, A.F., Beer Stolz, D., Morelli, A.E., Transgenic galectin-1 induces maturation of dendritic cells that elicit contrasting responses in naive and activated T cells (2006) J. Immunol., 176, pp. 7207-7220
• He, J., Baum, L.G., Presentation of galectin-1 by extracellular matrix triggers T cell death (2004) J. Biol. Chem., 279, pp. 4705-4712
• Morelli, A.E., Larregina, A.T., Ganster, R.W., Zahorchack, A.F., Plowey, J.M., Takayama, T., Logar, A., Thomson, A.W., Recombinant adenoviral induces maturation of dendritic cells via an NF-κB dependent pathway (2000) J. Virol., 74, pp. 9617-9628
• Levroney, E.L., Aguilar, H.C., Fulcher, J.A., Kohatsu, L., Pace, K.E., Pang, M., Gurney, K.B., Lee, B., Novel innate immune functions for galectin-1: Galectin-1 inhibits cell fusion by Nipah Virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines (2005) J. Immunol., 175, pp. 413-420
• Fulcher, J.A., Hashimi, S.T., Levroney, E.L., Pang, M., Gurney, K.B., Baum, L.G., Lee, B., Galectin-1 matured human monocyte-derived dendritic cells have enhanced migration through extracellular martrix (2006) J. Immunol., 177, pp. 216-226
• Haskins, K., McDuffie, M., Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone (1990) Science, 249, pp. 1433-1436
• Atkinson, M.A., Maclaren, N.K., Islet cell autoantigens in insulin-dependent diabetes (1993) J. Clin. Invest., 92, pp. 1608-1616
• Dias-Baruffi, M., Zhu, H., Cho, M., Karmakar, S., McEver, R.P., Cummings, R.D., Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosis (2003) J. Biol. Chem., 278, pp. 41282-41293
• Karmakar, S., Cummings, R.D., McEver, R.P., Contributions of Ca2+ to galectin-1-induced exposure of phosphatidylserine on activated neutrophils (2005) J. Biol. Chem., 280, pp. 28623-28631
• Roep, B.O., De Vries, R.R., T-lymphocytes and the pathogenesis of type 1 (insulin-dependent) diabetes mellitus (1992) Eur J. Clin. Invest., 22, pp. 697-711
• Cooper, D.N.W., Massa, S.M., Barondes, S.H., Endogenous muscle lectin inhibits myoblast adhesion to laminin (1991) J. Cell Biol., 115, pp. 1437-1448
• Tarbell, K.V., Yamazaki, S., Olson, K., Toy, P., Steinman, R.M., CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes (2004) J. Exp. Med., 199, pp. 1467-1477
• Höglund, P., Mintern, J., Waltzinger, C., Heath, W., Benoist, C., Mathis, D., Initiation of autoimmune diabetes by developmentally regulated presentation of islet cells antigens in the pancreatic lymph nodes (1999) J. Exp. Med., 189, pp. 331-339
• Tisch, R., Yang, X.D., Singer, S.M., Liblau, R.S., Fluger, L., McDevitt, H.O., Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice (1993) Nature, 366, pp. 72-75
• Chao, C.C., Sytwu, H.K., Chen, E.L., Toma, J., McDevitt, H.O., The role of MHC class II molecules in susceptibility of type I diabetes: Identification of peptide epitopes and characterization of the T cell repertoire (1999) Proc. Natl. Acad. Sci. USA, 96, pp. 9299-9304
• Katz, J.D., Benoist, C., Mathis, D., T helper cell subsets in insulin-dependent diabetes (1995) Science, 268, pp. 1185-1188
• Gepts, W., Pathologic anatomy of the pancreas in juvenile diabetes mellitus (1965) Diabetes, 14, pp. 619-633
• Roep, B.O., Kallan, A.A., De Vries, R.R., β-cell antigen-specific lysis of macrophages by CD4 T-cell clones from newly diagnosed IDDM patient: A putative mechanism of T-cell-mediated autoimmune islet cell destruction (1992) Diabetes, 41, pp. 1380-1384
• Roep, B.O., T-cell responses to autoantigens in IDDM: The search for the Holy Grail (1996) Diabetes, 45, pp. 1147-1156
• Stiller, C.R., Dupre, J., Gent, M., Jenner, M.R., Keown, P.A., Laupacis, A., Martell, R., Wolfe, B.M., Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset (1984) Science, 223, pp. 1362-1367
• Bougneres, P.F., Carel, J.C., Castano, L., Boitard, C., Gardin, J.P., Landais, P., Hors, J., Bach, J.F., Factors associated with early remission of type I diabetes in children treated with cyclosporine (1988) N. Engl. J. Med., 318, pp. 663-670
• Lampeter, E.F., Homberg, M., Quabeck, K., Schaefer, U.W., Wernet, P., Bertrams, J., Grosse-Wilde, H., Kolb, H., Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation (1993) Lancet, 341, pp. 1243-1244
• Wicker, L.S., Miller, B.J., Mullen, Y., Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice (1986) Diabetes, 35, pp. 855-860
• Bendelac, A., Carnaud, C., Boitard, C., Bach, J.F., Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and LyT-2+ T cells (1987) J. Exp. Med., 166, pp. 823-832
• Peterson, J.D., Haskins, K., Transfer of diabetes in the NOD-scid mouse by CD4 T cell clones: Differential requirement for CD8 T cells (1996) Diabetes, 45, pp. 328-336
• Ogawa, M., Maruyama, T., Hasegawa, T., Kanaya, T., Kobayashi, F., Tochino, Y., Uda, H., The inhibitory effect of neonatal thymectomy on the incidence of insulitis in non-obese diabetic (NOD) mice (1985) Biomed. Res., 6, p. 103
• Ikehara, S., Ohtsuki, H., Good, R.A., Asamoto, H., Nakamura, T., Sekita, K., Muso, E., Kuzuya, H., Prevention of type 1 diabetes in NOD mice by allogeneic bone marrow transplantation (1985) Proc. Natl. Acad. Sci. USA, 82, pp. 7743-7747
• Roep, B.O., Kallan, A.A., Duinkerken, G., Arden, S.D., Hutton, J.C., Braining, G.J., De Vries, R.R., T-cell reactivity to β-cell membrane antigens associated with β-cell destruction in IDDM (1995) Diabetes, 44, pp. 278-283
• Chang, J.C., Linarelli, L.G., Laxer, J.A., Froning, K.J., Caralli, L.L., Brostoff, S.W., Carlo, D.J., Insulin secretory-granule specific T cell clones in human IDDM (1995) J. Autoimmun., 8, pp. 221-234
• Chung, C.D., Patel, V.P., Moran, M., Lewis, L.A., Micelli, M.C., Galectin-1 induces partial TcR ζ-chain phosphorylation and antagonizes processive TCR signal transduction (2000) J. Immunol., 165, pp. 3722-3729
• Pace, K.E., Lee, C., Stewart, P.L., Baum, L.G., Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1 (1999) J. Immunol., 163, pp. 3801-3811
• Rabinovich, G.A., Alonso, C.R., Sotomayor, C.E., Durand, S., Bocco, J.L., Riera, C.M., Molecular mechanism implicated in galectin-1-induced apoptosis: Activation of the AP-1 transcription factor and downregulation of Bcl-2 (2000) Cell Death Differ., 7, pp. 747-753
• Cho, M., Cummings, R.D., Galectin-1, a β-galactoside-binding lectin in Chinese hamster ovary cells. I. Physical and chemical characterization (1995) J. Biol. Chem., 270, pp. 5198-5206
• Larregina, A.T., Morelli, A.E., Tkacheva, O., Erdos, G., Donahue, C., Watkins, S.C., Thomson, A.W., Falo Jr., L.D., Highly efficient expression of transgenic proteins by naked DNA-transfected dendritic cells through terminal differentiation (2004) Blood, 103, pp. 811-819
• Vespa, G.N.R., Lewis, L.A., Kozak, K.R., Moran, M., Nguyen, J.T., Baum, L.G., Miceli, M.C., Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis but inhibit IL-2 production and proliferation (1999) J. Immunol., 162, pp. 799-806
• Feili-Hariri, M., Falkner, D.H., Morel, P.A., Regulatory Th2 response induced following adoptive transfer of dendritic cells in prediabetic NOD mice (2002) Eur. J. Immunol., 32, pp. 2021-2030
• Feili-Hariri, M., Falkner, D.H., Gambotto, A., Papworth, G.D., Watkins, S.C., Robbins, P.R., Morel, P.A., Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advance insulins (2003) Hum. Gene Ther., 14, pp. 13-23
• Papaccio, G., Nicoletti, F., Pisanti, F.A., Bendtzen, K., Galdieri, M., Prevention of spontaneous autoimmune diabetes in NOD mice by transferring in vitro antigen-pulsed syngeneic dendritic cells (2000) Endocrinology, 141, pp. 1500-1505
• Morin, J., Faideau, B., Gagnerault, M.-C., Lepault, F., Boitard, C., Boudaly, S., Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice (2003) Clin. Exp. Immunol., 134, pp. 388-395
• Steptoe, R.J., Ritchie, J.M., Jones, L.K., Harrison, L.C., Autoimmune diabetes is suppressed by transfer of proinsulin-encoding Gr-1+ myeloid progenitor cells that differentiate in vivo into resting dendritic cells (2005) Diabetes, 54, pp. 434-442
• Krueger, T., Wohlrab, U., Klucken, M., Schott, M., Seissler, J., Autoantigen-specific protection of non-obese diabetic mice from cyclophosphamide-accelerated diabetes by vaccination with dendritic cells (2003) Diabetologia, 46, pp. 1357-1365
• Clare-Salzler, M.J., Brooks, J., Chai, A., Van Herle, K., Anderson, C., Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer (1992) J. Clin. Invest., 90, pp. 741-748
• Shinomiya, M., Fazle Akbar, S.M., Shinomiya, H., Onji, M., Transfer of dendritic cells (DC) ex vivo stimulated with interferon-γ (IFN-γ) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice (1999) Clin. Exp. Immunol., 117, pp. 38-43
• Ma, L., Qian, S., Liang, X., Wang, L., Woodward, J.E., Giannoukakis, N., Robbins, P.D., Lu, L., Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-κB activity (2003) Diabetes, 52, pp. 1976-1985
• Wegmann, D.R., Gill, R.G., Norbury-Glaser, M., Schloot, N., Daniel, D., Analysis of the spontaneous T cell response to insulin in NOD mice (1994) J. Autoimmun., 7, pp. 833-843
• Daaboul, J., Schatz, D., Overview of prevention and intervention trials for type 1 diabetes (2003) Rev. Endocr. Metab. Disord., 4, pp. 317-323

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