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interleukin 6

"Aesculus hippocastanum L. seed extract shows virucidal and antiviral activities against respiratory syncytial virus (RSV) and reduces lung inflammation in vivo" (2019) Salinas, F.M.;Vázquez, L.;Gentilini, M.V. (...)Bueno, C.A. Antiviral Research. 164:1-11

"Leptin action in normal and pathological pregnancies" (2018) Pérez-Pérez, A.;Toro, A.;Vilariño-García, T. (...)Sánchez-Margalet, V. Journal of Cellular and Molecular Medicine. 22(2):716-727

"Regulatory and mechanistic actions of glucocorticoids on T and inflammatory cells" (2018) Liberman, A.C.;Budziñski, M.L.;Sokn, C. (...)Arzt, E. Frontiers in Endocrinology. 9(MAY)

"Comparative proteomics of soluble factors secreted by human breast adipose tissue from tumor and normal breast" (2018) Fletcher, S.J.;Hapon, M.B.;Callegari, E.A. (...)Pistone-Creydt, V. Oncotarget. 9(57):31007-31017

"Peripheral neuroimmunoendocrine interactions: Contribution of TNFRp55 to the circadian synchronization of progesterone and cytokine production in joints of mice in late pregnancy" (2018) Arias, J.L.;Mayordomo, A.C.;Silva, J.E. (...)Di Genaro, M.S. NeuroImmunoModulation. 25(3):153-162

"Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer" (2017) Ramakrishnan, S.;Hu, Q.;Krishnan, N. (...)Woloszynska-Read, A. Cell Death and Disease. 8(12)

"Treatment with a new peroxisome proliferator-activated receptor gamma agonist, pyridinecarboxylic acid derivative, increases angiogenesis and reduces inflammatory mediators in the heart of Trypanosoma cruzi-infected mice" (2017) Penas, F.N.;Carta, D.;Dmytrenko, G. (...)Goren, N.B. Frontiers in Immunology. 8(DEC)

"Autocrine IL-6 mediates pituitary tumor senescence" (2017) Sapochnik, M.;Haedo, M.R.;Fuertes, M. (...)Arzt, E. Oncotarget. 8(3):4690-4702

"Progesterone and VIP cross-talk enhances phagocytosis and anti-inflammatory profile in trophoblast-derived cells" (2017) Vota, D.;Aguero, M.;Grasso, E. (...)Ramhorst, R. Molecular and Cellular Endocrinology. 443:146-154

"Programmed cell senescence: Role of IL-6 in the pituitary" (2017) Sapochnik, M.; Fuertes, M.; Arzt, E. Journal of Molecular Endocrinology. 58(4):R241-R253

"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139

"Lack of galectin-3 increases Jagged1/Notch activation in bone marrow-derived dendritic cells and promotes dysregulation of T helper cell polarization" (2016) Fermino, M.L.;Dylon, L.S.D.;Cecílio, N.T. (...)Bernardes, E.S. Molecular Immunology. 76:22-34

"Molecular Mechanisms Underlying Pituitary Pathogenesis" (2016) Sapochnik, M.; Nieto, L.E.; Fuertes, M.; Arzt, E. Biochemical Genetics. 54(2):107-119

"Synthetic stigmasterol derivatives inhibit capillary tube formation, herpetic corneal neovascularization and tumor induced angiogenesis: Antiangiogenic stigmasterol derivatives" (2016) Michelini, F.M.;Lombardi, M.G.;Bueno, C.A. (...)Alché, L.E. Steroids. 115:160-168

"Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway" (2015) Bueno, C.A.;Michelini, F.M.;Pertino, M.W. (...)Alché, L.E. Medical Microbiology and Immunology. 204(5):575-584

"IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness" (2015) Ziblat, A.;Domaica, C.I.;Spallanzani, R.G. (...)Zwirner, N.W. European Journal of Immunology. 45(1):192-202

"Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells" (2015) Iraporda, C.;Errea, A.;Romanin, D.E. (...)Rumbo, M. Immunobiology. 220(10):1161-1169

"Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period" (2015) Paparini, D.;Gori, S.;Grasso, E. (...)Salamone, G. Acta Physiologica. 214(2):237-247

"Effect of the potent antiviral 1-cinnamoyl-3,11-dihydroxymeliacarpin on cytokine production by murine macrophages stimulated with HSV-2" (2014) Petrera, E.; Coto, C.E. Phytotherapy Research. 28(1):104-109

"In vitro and in vivo immunomodulatory activity of sulfated polysaccharides from red seaweed Nemalion helminthoides" (2014) Pérez-Recalde, M.; Matulewicz, M.C.; Pujol, C.A.; Carlucci, M.J. International Journal of Biological Macromolecules. 63:38-42

"Altered expression of cytokines in mice infected intranasally with two syncytial variants of Herpes simplex virus type 1" (2014) Carolina Artuso, M.;Linero, F.N.;Gazzaniga, S. (...)Carlucci, M.J. Microbial Pathogenesis. 71-72(1):68-72

"Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment" (2014) Croci, D.O.;Cerliani, J.P.;Pinto, N.A. (...)Rabinovich, G.A. Glycobiology. 24(12):1283-1290

"Antiviral Action of Synthetic Stigmasterol Derivatives on Herpes Simplex Virus Replication in Nervous Cells in Vitro" (2014) Petrera, E.; Níttolo, A.G.; Alché, L.E. BioMed Research International. 2014

"Naturally occurring compounds elicit hiv-1 replication in chronically infected promonocytic cells" (2014) Barquero, A.A.;Dávola, M.E.;Riva, D.A. (...)Alché, L.E. BioMed Research International. 2014

"Molecular basis of mineralocorticoid receptor action in the nervous system" (2013) Molinari, A.M.;Machado-Rada, M.Y.;Mazaira, G.I. (...)Galigniana, M.D. CNS and Neurological Disorders - Drug Targets. 12(8):1163-1174

"Contribution of vasoactive intestinal peptide to immune homeostasis in trophoblast-maternal leukocyte interaction under LPS stimulation" (2013) Fraccaroli, L.;Grasso, E.;Hauk, V. (...)Ramhorst, R. NeuroImmunoModulation. 21(1):21-30

"Peripheral and central inflammation in autism spectrum disorders" (2013) Depino, A.M. Molecular and Cellular Neuroscience. 53:69-76

"Parasite infections in multiple sclerosis modulate immune responses through a retinoic acid-dependent pathway" (2013) Correale, J.; Farez, M.F. Journal of Immunology. 191(7):3827-3837

"Unveiling the association of STAT3 and HO-1 in prostate cancer: Role beyond heme degradation" (2012) Elguero, B.;Gueron, G.;Giudice, J. (...)Vazquez, E. Neoplasia (United States). 14(11):1043-1056

"Advanced prostate cancer: Reinforcing the strings between inflammation and the metastatic behavior" (2012) Gueron, G.; De Siervi, A.; Vazquez, E. Prostate Cancer and Prostatic Diseases. 15(3):213-221

"A natural antiviral and immunomodulatory compound with antiangiogenic properties" (2012) Bueno, C.A.; Lombardi, M.G.; Sales, M.E.; Alché, L.E. Microvascular Research. 84(3):235-241

"Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer" (2012) Rabinovich, G.; Croci, D.O. Immunity. 36(3):322-335

"Early and adult hippocampal TGF-β1 overexpression have opposite effects on behavior" (2011) Depino, A.M.; Lucchina, L.; Pitossi, F. Brain, Behavior, and Immunity. 25(8):1582-1591

"Key questions in metastasis: New insights in molecular pathways and therapeutic implications" (2011) Gueron, G.; de Siervi, A.; Vazquez, E. Current Pharmaceutical Biotechnology. 12(11):1867-1880

"Serine leucocyte proteinase inhibitor-treated monocyte inhibits human CD4+ lymphocyte proliferation" (2011) Guerrieri, D.;Tateosian, N.L.;Maffía, P.C. (...)Chuluyan, H.E. Immunology. 133(4):434-441

"Lymphocytic choriomeningitis virus (LCMV) infection of macaques: A model for Lassa fever" (2011) Zapata, J.C.;Pauza, C.D.;Djavani, M.M. (...)Salvato, M.S. Antiviral Research. 92(2):125-138

"Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan" (2011) Mateu, C.G.;Recalde, M.P.;Artuso, M.C. (...)Carlucci, M.J. Sexually Transmitted Diseases. 38(6):555-561

"Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology" (2010) Fuertes, M.;Gerez, J.;Haedo, M. (...)Arzt, E. Frontiers of Hormone Research. 38:1-6

"NeuroImmunoModulation: Preface" (2010) Pérez Leirós, C.; Arzt, E.; Saravia, F.; Rettori, V. NeuroImmunoModulation. 17(3):137-138

"Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells" (2010) Schaaf, C.;Shan, B.;Onofri, C. (...)Renner, U. Neuroendocrinology. 91(2):200-210

"Turning 'sweet' on immunity: Galectin-glycan interactions in immune tolerance and inflammation" (2009) Rabinovich, G.A.; Toscano, M.A. Nature Reviews Immunology. 9(5):338-352

"VIP modulates the pro-inflammatory maternal response, inducing tolerance to trophoblast cells" (2009) Fraccaroli, L.;Alfieri, J.;Larocca, L. (...)Leirós, C.P. British Journal of Pharmacology. 156(1):116-126

"Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive C protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients " (2009) Menéndez, A.Ma.;De Portela, Ma.L.P.M.;Weisstaub, A. (...)Zeni, S. Nutricion Hospitalaria. 24(3):340-346

"A natural tetranortriterpenoid with immunomodulating properties as a potential anti-HSV agent" (2009) Bueno, C.A.;Barquero, A.A.;Di Cónsoli, H. (...)Alché, L.E. Virus Research. 141(1):47-54

"Dehydroepiandrosterone and metformin modulate progesterone-induced blocking factor (PIBF), cyclooxygenase 2 (COX2) and cytokines in early pregnant mice" (2008) Luchetti, C.G.;Mikó, E.;Szekeres-Bartho, J. (...)Motta, A.B. Journal of Steroid Biochemistry and Molecular Biology. 111(3-5):200-207

"The in vitro immunomodulatory activity of a synthetic brassinosteroid analogue would account for the improvement of herpetic stromal keratitis in mice" (2008) Michelini, F.M.; Berra, A.; Alché, L.E. Journal of Steroid Biochemistry and Molecular Biology. 108(1-2):164-170

"Neuroimmune-endocrine interactions during early pregnancy in an autoimmune context: Focus on macrophage activation" (2008) Larocca, L.;Ramhorst, R.;Roca, V. (...)Pérez Leirós, C. NeuroImmunoModulation. 15(1):84-90

"Molecular transduction mechanisms of cytokine-hormone interactions: Role of gp130 cytokines" (2007) Gerez, J.;Bonfiglio, J.;Sosa, S. (...)Arzt, E. Experimental Physiology. 92(5):801-806

"Pituitary action of cytokines: Focus on BMP-4 and gp130 family" (2007) Giacomini, D.;Acuña, M.;Gerez, J. (...)Arzt, E. Neuroendocrinology. 85(2):94-100

"Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation" (2006) Dekanty, A.;Sauane, M.;Cadenas, B. (...)Jiménez De Asúa, L. Journal of Biological Chemistry. 281(10):6136-6143

"Estradiol Stimulates Vascular Endothelial Growth Factor and Interleukin-6 in Human Lactotroph and Lactosomatotroph Pituitary Adenomas" (2004) Onofri, C.;Carbia Nagashima, A.;Schaaf, L. (...)Arzt, E. Experimental and Clinical Endocrinology and Diabetes. 112(1):18-23

"Intracellular Proteins and Mechanisms Involved in the Control of gp130/JAK/STAT Cytokine Signaling" (2004) Carbia-Nagashima, A.; Arzt, E. IUBMB Life. 56(2):83-88

"Functional in vitro studies on the role and regulation of interleukin-6 in human somatotroph pituitary adenomas" (2003) Thiele, J.-O.;Lohrer, P.;Schaaf, L. (...)Renner, U. European Journal of Endocrinology. 149(5):455-461

"Immunostimulatory effects of plasmid DNA and synthetic oligodeoxynucleotides" (2003) Zelenay, S.; Elías, F.; Fló, J. European Journal of Immunology. 33(5):1382-1392

"Time course of T-cell responses to MOG and MBP in patients with clinically isolated syndromes" (2003) Correale, J.; Bassani Molinas, M.D.L.M. Journal of Neuroimmunology. 136(1-2):162-171

"Effect of leptin on progesterone, human chorionic gonadotropin, and interleukin-6 secretion by human term trophoblast cells in culture" (2003) Cameo, P.; Bischof, P.; Calvo, J.C. Biology of Reproduction. 68(2):472-477

"Transcriptional regulation of interleukin-6 in pituitary folliculo-stellate TtT/GF cells" (2003) Carbia Nagashima, A.C.;Giacomini, D.;Perez Castro, C. (...)Arzt, E. Molecular and Cellular Endocrinology. 201(1-2):47-56

"Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth, and tumor development of pituitary lactosomatotrophic GH3 cells" (2003) Perez Castro, C.;Giacomini, D.;Carbia Nagashima, A. (...)Arzt, E. Endocrinology. 144(2):693-700

"Increased splenocyte proliferative response and cytokine production in β-endorphin-deficient mice" (2002) Refojo, D.;Kovalovsky, D.;Young, J.I. (...)Arzt, E. Journal of Neuroimmunology. 131(1-2):126-134

"gp130 cytokine signaling in the pituitary gland: A paradigm for cytokine-neuro-endocrine pathways" (2001) Arzt, E. Journal of Clinical Investigation. 108(12):1729-1733

"Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures" (2001) Perez Castro, C.;Carbia Nagashima, A.;Páez Pereda, M. (...)Arzt, E. Journal of Endocrinology. 169(3):539-547

"Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38α mitogen-activated protein kinase/nuclear factor-κB pathway" (2000) Lohrer, P.;Gloddek, J.;Carbia Nagashima, A. (...)Renner, U. Endocrinology. 141(12):4457-4465

"Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human corticotroph pituitary adenomas" (2000) Páez Pereda, M.;Lohrer, P.;Kovalovsky, D. (...)Arzt, E. Experimental and Clinical Endocrinology and Diabetes. 108(3):202-207

"Pathophysiological role of the cytokine network in the anterior pituitary gland" (1999) Arzt, E.;Pereda, M.P.;Castro, C.P. (...)Stalla, G.K. Frontiers in Neuroendocrinology. 20(1):71-95

"Pituitary adenylate cyclase-activating polypeptide, interleukin-6 and glucocorticoids regulate the release of vascular endothelial growth factor in pituitary folliculostellate cells" (1999) Gloddek, J.;Pagotto, U.;Paez Pereda, M. (...)Renner, U. Journal of Endocrinology. 160(3):483-490

"Regulation of the intrapituitary IL-6 production in response to LPS and glucocorticoids: A novel route of immune-endocrine cross talk" (1998) Renner, U.; Gloddek, J.; Arzt, E.; Stalla, G.K. Experimental and Clinical Endocrinology and Diabetes. 106(1)

"Determination of IL-1 and IL-6 levels in human embryo culture-conditioned media" (1997) Barañao, R.I.; Piazza, A.; Rumi, L.S.; De Fried, E.P. American Journal of Reproductive Immunology. 37(2):191-194

"Tumor cells engineered to express interleukin-6 exhibit a reduced tumorigenicity depending on the tumor cell model." (1996) Ledda, M.F.;Adris, S.;Bravo, A.I. (...)Podhajcer, O.L. Cellular and molecular biology (Noisy-le-Grand, France). 42(5):769-778

"Anti-tumor activity of cytokines against opportunistic vascular tumors in mice" (1996) Dong, Q.G.;Graziani, A.;Garlanda, C. (...)Bussolino, F. International Journal of Cancer. 65(5):700-708

"Interleukin-2 (IL-2) and IL-6 regulate c-fos protooncogene expression in human pituitary adenoma explants" (1996) Páez Pereda, M.;Goldberg, V.;Chervín, A. (...)Arzt, E. Molecular and Cellular Endocrinology. 124(1-2):33-42

"Insulin effect on interleukin 1 (IL-1) and interleukin 6 (IL-6) production by lipopolysaccharide-stimulated human monocytes" (1994) Schillaci, R.; Eugui, E.M.; Roldan, A. Hormone and Metabolic Research. 26(2):113-115