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tumor necrosis factor alpha

"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139

"Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1" (2016) Ge, X.N.;Ha, S.G.;Greenberg, Y.G. (...)Sriramarao, P. Proceedings of the National Academy of Sciences of the United States of America. 113(33):E4837-E4846

"Juvenile exposure to a high fat diet promotes behavioral and limbic alterations in the absence of obesity" (2016) Vinuesa, A.;Pomilio, C.;Menafra, M. (...)Saravia, F. Psychoneuroendocrinology. 72:22-33

"Small molecules as anti-TNF drugs" (2015) Richmond, V.;Michelini, F.M.;Bueno, C.A. (...)Ramírez, J.A. Current Medicinal Chemistry. 22(25):2920-2942

"Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway" (2015) Bueno, C.A.;Michelini, F.M.;Pertino, M.W. (...)Alché, L.E. Medical Microbiology and Immunology. 204(5):575-584

"Dendritic cell-based vaccination in cancer: Therapeutic implications emerging from murine models" (2015) Mac Keon, S.; Ruiz, M.S.; Gazzaniga, S.; Wainstok, R. Frontiers in Immunology. 6(MAY)

"Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period" (2015) Paparini, D.;Gori, S.;Grasso, E. (...)Salamone, G. Acta Physiologica. 214(2):237-247

"Effect of the potent antiviral 1-cinnamoyl-3,11-dihydroxymeliacarpin on cytokine production by murine macrophages stimulated with HSV-2" (2014) Petrera, E.; Coto, C.E. Phytotherapy Research. 28(1):104-109

"Atheroprotective remodelling of vascular dermatan sulphate proteoglycans in response to hypercholesterolaemia in a rat model" (2014) Oberkersch, R.;Maccari, F.;Bravo, A.I. (...)Calabrese, G.C. International Journal of Experimental Pathology. 95(3):181-190

"In vitro and in vivo immunomodulatory activity of sulfated polysaccharides from red seaweed Nemalion helminthoides" (2014) Pérez-Recalde, M.; Matulewicz, M.C.; Pujol, C.A.; Carlucci, M.J. International Journal of Biological Macromolecules. 63:38-42

"The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy" (2014) Orqueda, A.J.;Dansey, M.V.;Español, A. (...)Pecci, A. Biochemical Pharmacology. 89(4):526-535

"Altered expression of cytokines in mice infected intranasally with two syncytial variants of Herpes simplex virus type 1" (2014) Carolina Artuso, M.;Linero, F.N.;Gazzaniga, S. (...)Carlucci, M.J. Microbial Pathogenesis. 71-72(1):68-72

"Differential migration and activation profile of monocytes after trophoblast interaction" (2014) Grasso, E.;Paparini, D.;Hauk, V. (...)Ramhorst, R. PLoS ONE. 9(5)

"Naturally occurring compounds elicit hiv-1 replication in chronically infected promonocytic cells" (2014) Barquero, A.A.;Dávola, M.E.;Riva, D.A. (...)Alché, L.E. BioMed Research International. 2014

"Molecular basis of mineralocorticoid receptor action in the nervous system" (2013) Molinari, A.M.;Machado-Rada, M.Y.;Mazaira, G.I. (...)Galigniana, M.D. CNS and Neurological Disorders - Drug Targets. 12(8):1163-1174

"Protective action of erythropoietin on neuronal damage induced by activated microglia" (2013) Wenker, S.D.; Chamorro, M.E.; Vittori, D.C.; Nesse, A.B. FEBS Journal. 280(7):1630-1642

"Bayesian Approach to Model CD137 Signaling in Human M. tuberculosis In Vitro Responses" (2013) Fernández Do Porto, D.A.;Auzmendi, J.;Peña, D. (...)Moffatt, L. PLoS ONE. 8(2)

"Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype" (2013) Rostoker, R.;Yaseen, H.;Schif-Zuck, S. (...)Ariel, A. Prostaglandins and Other Lipid Mediators. 107:85-94

"Mesenchymal stem cells and their use in therapy: What has been achieved?" (2013) Fernández Vallone, V.B.;Romaniuk, M.A.;Choi, H. (...)Chasseing, N.A. Differentiation. 85(1-2):1-10

"Peripheral and central inflammation in autism spectrum disorders" (2013) Depino, A.M. Molecular and Cellular Neuroscience. 53:69-76

"Parasite infections in multiple sclerosis modulate immune responses through a retinoic acid-dependent pathway" (2013) Correale, J.; Farez, M.F. Journal of Immunology. 191(7):3827-3837

"Tolerance Induction at the Early Maternal-Placental Interface Through Selective Cell Recruitment and Targeting by Immune Polypeptides" (2013) Pérez Leirós, C.; Ramhorst, R. American Journal of Reproductive Immunology. 69(4):359-368

"Advanced prostate cancer: Reinforcing the strings between inflammation and the metastatic behavior" (2012) Gueron, G.; De Siervi, A.; Vazquez, E. Prostate Cancer and Prostatic Diseases. 15(3):213-221

"CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis" (2012) Fernández Do Porto, D.A.;Jurado, J.O.;Pasquinelli, V. (...)García, V.E. Immunology and Cell Biology. 90(4):449-456

"A natural antiviral and immunomodulatory compound with antiangiogenic properties" (2012) Bueno, C.A.; Lombardi, M.G.; Sales, M.E.; Alché, L.E. Microvascular Research. 84(3):235-241

"Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis" (2012) Garay, L.I.;González Deniselle, M.C.;Brocca, M.E. (...)De Nicola, A.F. Neuroscience. 226:40-50

"Growth hormone modulation of insulin signaling in the heart" (2012) Miquet, J.G. Cell Cycle. 11(5):827-828

"Oral administration of fluoxetine alters the proliferation/apoptosis balance of lymphoma cells and up-regulates T cell immunity in tumor-bearing mice" (2011) Frick, L.R.;Rapanelli, M.;Arcos, M.L.B. (...)Genaro, A.M. European Journal of Pharmacology. 659(2-3):265-272

"Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1" (2011) Toscano, M.A.;Campagna, L.;Molinero, L.L. (...)Rabinovich, G.A. Molecular Immunology. 48(15-16):1940-1949

"A deep rough type structure in Bordetella bronchiseptica lipopolysaccharide modulates host immune responses" (2011) Sisti, F.;Fernández, J.;Higgins, S.C. (...)Hozbor, D. Microbiology and Immunology. 55(12):847-854

"Vasoactive intestinal peptide/vasoactive intestinal peptide receptor relative expression in salivary glands as one endogenous modulator of acinar cell apoptosis in a murine model of Sjögren's syndrome" (2011) Hauk, V.;Calafat, M.;Larocca, L. (...)Leirós, C.P. Clinical and Experimental Immunology. 166(3):309-316

"Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan" (2011) Mateu, C.G.;Recalde, M.P.;Artuso, M.C. (...)Carlucci, M.J. Sexually Transmitted Diseases. 38(6):555-561

"Tumor necrosis factor alpha induces LIF expression through ERK1/2 activation in mammary epithelial cells" (2010) Levy, C.S.;Slomiansky, V.;Gattelli, A. (...)Kordon, E.C. Journal of Cellular Biochemistry. 110(4):857-865

"c-FLIP is involved in erythropoietin-mediated protection of erythroid-differentiated cells from TNF-α-induced apoptosis" (2010) Vittori, D.;Vota, D.;Callero, M. (...)Nesse, A. Cell Biology International. 34(6):621-630

"Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog" (2009) Careaga, V.P.;Bueno, C.;Muniain, C. (...)Maier, M.S. Chemotherapy. 55(1):60-68

"Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant rat" (2009) Hernandez, F.;Peluffo, M.C.;Bas, D. (...)Tesone, M. Molecular Reproduction and Development. 76(12):1153-1164

"New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects" (2009) Pecci, A.;Alvarez, L.D.;Veleiro, A.S. (...)Burton, G. Journal of Steroid Biochemistry and Molecular Biology. 113(3-5):155-162

"A potential tolerogenic immune mechanism in a trophoblast cell line through the activation of chemokine-induced T cell death and regulatory T cell modulation" (2009) Fraccaroli, L.;Alfieri, J.;Larocca, L. (...)Ramhorst, R. Human Reproduction. 24(1):166-175

"Vasoactive intestinal peptide inhibits TNF-α-induced apoptotic events in acinar cells from nonobese diabetic mice submandibular glands" (2009) Calafat, M.;Larocca, L.;Roca, V. (...)Pérez Leirós, C. Arthritis Research and Therapy. 11(2)

"Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms" (2009) Frick, L.R.; Rapanelli, M.; Cremaschi, G.A.; Genaro, A.M. Brain, Behavior, and Immunity. 23(1):36-40

"TNF-alpha-induced apoptosis is prevented by erythropoietin treatment on SH-SY5Y cells" (2009) Pregi, N.;Wenker, S.;Vittori, D. (...)Nesse, A. Experimental Cell Research. 315(3):419-431

"A natural tetranortriterpenoid with immunomodulating properties as a potential anti-HSV agent" (2009) Bueno, C.A.;Barquero, A.A.;Di Cónsoli, H. (...)Alché, L.E. Virus Research. 141(1):47-54

"Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection" (2009) Petrera, E.; Coto, C.E. Phytotherapy Research. 23(12):1771-1777

"Chronic restraint stress impairs T-cell immunity and promotes tumor progression in mice" (2009) Frick, L.R.;Barreiro Arcos, M.L.;Rapanelli, M. (...)Cremaschi, G.A. Stress. 12(2):134-143

"The in vitro immunomodulatory activity of a synthetic brassinosteroid analogue would account for the improvement of herpetic stromal keratitis in mice" (2008) Michelini, F.M.; Berra, A.; Alché, L.E. Journal of Steroid Biochemistry and Molecular Biology. 108(1-2):164-170

"Neuroimmune-endocrine interactions during early pregnancy in an autoimmune context: Focus on macrophage activation" (2008) Larocca, L.;Ramhorst, R.;Roca, V. (...)Pérez Leirós, C. NeuroImmunoModulation. 15(1):84-90

"VIP limits LPS-induced nitric oxide production through IL-10 in NOD mice macrophages" (2007) Larocca, L.;Calafat, M.;Roca, V. (...)Leirós, C.P. International Immunopharmacology. 7(10):1343-1349

"Syntheses of immunomodulating androstanes and stigmastanes: Comparison of their TNF-α inhibitory activity" (2007) Ramírez, J.A.;Bruttomesso, A.C.;Michelini, F.M. (...)Galagovsky, L.R. Bioorganic and Medicinal Chemistry. 15(24):7538-7544

"Reduced nitric oxide synthase and cyclo-oxygenase activity in the uterus of non-obese diabetic mice" (2006) Roca, V.;Larocca, L.;Calafat, M. (...)Leirós, C.P. Reproduction. 132(6):931-938

"6,19-Sulfur-bridged progesterone analogues with antiimmunosuppressive activity" (2005) Veleiro, A.S.;Pecci, A.;Monteserín, M.C. (...)Burton, G. Journal of Medicinal Chemistry. 48(18):5675-5683

"Divergent effects of the major mast cell products histamine, tryptase and TNF-alpha on human fibroblast behaviour" (2005) Albrecht, M.;Frungieri, M.B.;Kunz, L. (...)Mayerhofer, A. Cellular and Molecular Life Sciences. 62(23):2867-2876

"Different enzymatic activities recruitment by specific domains of TIF2 are involved in NF-κB transactivation " (2004) Nojek, I.M.;Werbajh, S.E.;Colo, G.P. (...)Costas, M.A. Medicina. 64(2):135-138

"Paradoxical effects of tumour necrosis factor-α on rat granulosa cell DNA synthesis" (2002) Lanuza, G.M.; Saragüeta, P.E.; Bussmann, U.A.; Barañao, J.L. Reproduction, Fertility and Development. 14(3-4):133-139

"Increased splenocyte proliferative response and cytokine production in β-endorphin-deficient mice" (2002) Refojo, D.;Kovalovsky, D.;Young, J.I. (...)Arzt, E. Journal of Neuroimmunology. 131(1-2):126-134

"Osmotic stress sensitizes naturally resistant cells to TNF-α-induced apoptosis" (2002) Franco, D.L.;Nojek, I.M.;Molinero, L. (...)Costas, M.A. Cell Death and Differentiation. 9(10):1090-1098

"Tumor necrosis factor-alfa production by monocytes from lung and colorectal cancer patients" (2001) Trejo, Y.G.;Bordenave, R.H.;Beviacqua, M. (...)Rumi, L.S. Journal of Experimental and Clinical Cancer Research. 20(1):71-73

"In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients" (2001) Trejo, Y.G.; Bordenave, R.H.; Beviacqua, M.; Rumi, L.S. Respiratory Medicine. 95(4):243-245

"Endothelial dysfunction, nitric oxide and platelet activation in hypertensive and diabetic type II patients" (2001) Ouvia, S.M.;La Greca, R.D.;Zanaro, N.L. (...)Sassetti, B. Thrombosis Research. 102(2):107-114

"Transrepression of NF-κB is not required for glucocorticoid-mediated protection of TNF-α-induced apoptosis on fibroblasts" (2000) Costas, M.A.; Müller Igaz, L.; Holsboer, F.; Arzt, E. Biochimica et Biophysica Acta - Molecular Cell Research. 1499(1-2):122-129

"Functional cross-talk among cytokines, T-cell receptor, and glucocorticoid receptor transcriptional activity and action" (2000) Arzt, E.;Kovalovsky, D.;Müller Igaz, L. (...)Holsboer, F. Annals of the New York Academy of Sciences. 917:672-677

"Gene therapy for rheumatoid arthritis. Theoretical considerations" (1998) Chernajovsky, Y.;Annenkov, A.;Herman, C. (...)Baker, D. Drugs and Aging. 12(1):29-41

"Molecular and functional evidence for in vitro cytokine enhancement of human and murine target cell sensitivity to glucocorticoids: TNF-α priming increases glucocorticoid inhibition of TNF-α-induced cytotoxicity/apoptosis" (1996) Costas, M.;Trapp, T.;Pereda, M.P. (...)Arzt, E. Journal of Clinical Investigation. 98(6):1409-1416

"Anti-tumor activity of cytokines against opportunistic vascular tumors in mice" (1996) Dong, Q.G.;Graziani, A.;Garlanda, C. (...)Bussolino, F. International Journal of Cancer. 65(5):700-708

"Superinduction of Mitogen-Stimulated Interferon-γ Production and Other Lymphokines by Sendai Virus" (1993) Costas, M.A.;Mella, D.;Criscuolo, M. (...)Arzt, E. Journal of Interferon Research. 13(6):407-412