Registro:

Referencias:

• Acs, P., Kipp, M., Norkute, A., Johann, S., Clarner, T., Braun, A., Berente, Z., Beyer, C., 17Beta-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice (2009) Glia, 57, pp. 807-814
• Alfonso-Loeches, S., Pascual-Lucas, M., Blanco, A.M., Sanchez-Vera, I., Guerri, C., Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage (2010) J Neurosci, 30, pp. 8285-8295
• Arnett, H.A., Fancy, S.P., Alberta, J.A., Zhao, C., Plant, S.R., Kaing, S., Raine, C.S., Stiles, C.D., BHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS (2004) Science, 306, pp. 2111-2115
• Ayers, M.M., Hazelwood, L.J., Catmull, D.V., Wang, D., McKormack, Q., Bernard, C., Orian, J.M., Early glial responses in murine models of multiple sclerosis (2004) Neurochem Int, 45, pp. 409-419
• Bebo, B.F., Fyfe-Johnson, A., Adlard, K., Beam, A.G., Vandenbark, A.A., Offner, H., Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains (2001) J Immunol, 166, pp. 2080-2089
• Brinton, R.D., Thompson, R.F., Foy, M.R., Baudry, M., Wang, J., Finch, C.E., Morgan, T.E., Nilsen, J., Progesterone receptors: form and function in brain (2008) Front Neuroendocrinol, 29, pp. 313-339
• Brown, G.C., Neher, J.J., Inflammatory neurodegeneration and mechanisms of microglial killing of neurons (2010) Mol Neurobiol, 41, pp. 242-247
• Bsibsi, M., Ravid, R., Gveric, D., van Noort, J.M., Broad expression of Toll-like receptors in the human central nervous system (2002) J Neuropathol Exp Neurol, 61, pp. 1013-1021
• Cai, J., Zhu, Q., Zheng, K., Li, H., Qi, Y., Cao, Q., Qiu, M., Co-localization of Nkx6.2 and NKx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes (2010) Glia, 58, pp. 458-468
• Cammer, W., Effects of TNFalpha on immature and mature oligodendrocytes and their progenitors in vitro (2000) Brain Res, 864, pp. 213-219
• Chang, A., Tourtellotte, W.W., Rudick, R., Trapp, B.D., Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis (2002) N Engl J Med, 346, pp. 165-173
• Chen, G., Shi, J., Jin, W., Wang, L., Xie, W., Sun, J., Hang, C., Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion (2008) Ann Clin Lab Sci, 38, pp. 65-74
• Chen, K.B., Uchida, K., Nakajima, H., Hayama, T., Hirai, T., Rodriguez Guerrero, A., Kobayashi, S., Baba, H., Tumor necrosis factor-alpha antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury (2011) Spine, 36, pp. 1350-1358
• Confavreux, C., Hutchinson, M., Hours, M.M., Cortinovis-Tourniaire, P., Moreau, T., Rate of pregnancy-related relapse in multiple sclerosis. Pregnancy in Multiple Sclerosis Group (1998) N Engl J Med, 339, pp. 285-291
• Dang, J., Mitkari, B., Kipp, M., Beyer, C., Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats (2011) Brain Behav Immun, 25, pp. 715-726
• De Nicola, A.F., Labombarda, F., Deniselle, M.C., Gonzalez, S.L., Garay, L., Meyer, M., Gargiulo, G., Schumacher, M., Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration (2009) Front Neuroendocrinol, 30, pp. 173-187
• Deniselle, M.C., Carreras, M., Garay, L., Gargiulo-Monachelli, G., Meyer, M., Poderoso, J.J., De Nicola, A.F., Progesterone prevents mitochondrial dysfunction in the spinal cord of Wobbler mice (2012) J Neurochem, 122, pp. 185-195
• Druckmann, R., Druckmann, M.A., Progesterone and the immunology of pregnancy (2005) J Steroid Biochem Mol Biol, 97, pp. 389-396
• El-Etr, M., Vukusic, S., Gignoux, L., Durand-Dubief, F., Achiti, I., Baulieu, E.E., Confavreux, C., Steroid hormones in multiple sclerosis (2005) J Neurol Sci, 233, pp. 49-54
• Elloso, M.M., Phiel, K., Henderson, R.A., Harris, H.A., Adelman, S.J., Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands (2005) J Endocrinol, 185, pp. 243-252
• Fancy, S.P., Zhao, C., Franklin, R.J., Increased expression of NKx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS (2004) Mol Cell Neurosci, 27, pp. 247-254
• Ferrini, M., Lima, A., De Nicola, A.F., Estradiol abolishes autologous down regulation of glucocorticoid receptors in brain (1995) Life Sci, 57, pp. 2403-2412
• Franklin, R.J., Ffrench-Constant, C., Remyelination in the CNS: from biology to therapy (2008) Nat Rev Neurosci, 9, pp. 839-855
• Garay, L., Deniselle, M.C., Lima, A., Roig, P., De Nicola, A.F., Effects of progesterone in the spinal cord of a mouse model of multiple sclerosis (2007) J Steroid Biochem Mol Biol, 107, pp. 228-237
• Garay, L., Gonzalez Deniselle, M., Gierman, L., Meyer, M., Lima, A., Roig, P., De Nicola, A.F., Steroid protection in the experimental autoimmune encephalomyelitis model of multiple sclerosis (2008) Neuroimmunomodulation, 15, pp. 76-83
• Garay, L., Deniselle, M.C., Meyer, M., Costa, J.J., Lima, A., Roig, P., De Nicola, A.F., Protective effects of progesterone administration on axonal pathology in mice with experimental autoimmune encephalomyelitis (2009) Brain Res, 1283, pp. 177-185
• Garay, L., Tungler, V., Deniselle, M.C., Lima, A., Roig, P., De Nicola, A.F., Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cord (2011) Neuroscience, 192, pp. 588-597
• Ghoumari, A.M., Baulieu, E.E., Schumacher, M., Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures (2005) Neuroscience, 135, pp. 47-58
• Giatti, S., Caruso, D., Boraso, M., Abbiati, F., Ballarini, E., Calabrese, D., Pesaresi, M., Melcangi, R.C., Neuroprotective effects of progesterone in chronic experimental autoimmune encephalomyelitis (2012) J Neuroendocrinol, 24, pp. 851-861
• Gibson, C.L., Constantin, D., Prior, M.J., Bath, P.M., Murphy, S.P., Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia (2005) Exp Neurol, 193, pp. 522-530
• Gonzalez Deniselle, M.C., Garay, L., Gonzalez, S., Saravia, F., Labombarda, F., Guennoun, R., Schumacher, M., De Nicola, A.F., Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons (2007) Exp Neurol, 203, pp. 406-414
• Guo, X., Harada, C., Namekata, K., Mitamura, Y., Yoshida, H., Matsumoto, Y., Harada, T., Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice (2010) PLoS One, 5, pp. e13083
• Hanke, M.L., Kielian, T., Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential (2011) Clin Sci (Lond), 121, pp. 367-387
• He, J., Evans, C.O., Hoffman, S.W., Oyesiku, N.M., Stein, D.G., Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury (2004) Exp Neurol, 189, pp. 404-412
• Hughes, M.D., Multiple sclerosis and pregnancy (2004) Neurol Clin, 22, pp. 757-769
• Hussain, R., El-Etr, M., Gaci, O., Rakotomamonjy, J., Macklin, W.B., Kumar, N., Sitruk-Ware, R., Ghoumari, A.M., Progesterone and nestorone facilitate axon remyelination: a role for progesterone receptors (2011) Endocrinology, 152, pp. 3820-3831
• Ibanez, C., Shields, S.A., El-Etr, M., Baulieu, E.E., Schumacher, M., Franklin, R.J., Systemic progesterone administration results in a partial reversal of the age-associated decline in CNS remyelination following toxin-induced demyelination in male rats (2004) Neuropathol Appl Neurobiol, 30, pp. 80-89
• Jiang, H., Curran, S., Ruiz-Vazquez, E., Liang, B., Winchester, R., Chess, L., Regulatory CD8+ T cells fine-tune the myelin basic protein-reactive T cell receptor V beta repertoire during experimental autoimmune encephalomyelitis (2003) Proc Natl Acad Sci USA, 100, pp. 8378-8383
• Kim, S., Liva, S.M., Dalal, M.A., Verity, M.A., Voskuhl, R.R., Estriol ameliorates autoimmune demyelinating disease: implications for multiple sclerosis (1999) Neurology, 52, pp. 1230-1238
• Koenig, H.L., Schumacher, M., Ferzaz, B., Thi, A.N., Ressouches, A., Guennoun, R., Jung-Testas, I., Baulieu, E.E., Progesterone synthesis and myelin formation by Schwann cells (1995) Science, 268, pp. 1500-1503
• Labombarda, F., Gonzalez, S., Lima, A., Roig, P., Guennoun, R., Schumacher, M., De Nicola, A.F., Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury (2009) Glia, 57, pp. 884-897
• Lee, J., Wu, Y., Qi, Y., Xue, H., Liu, Y., Scheel, D., German, M., Gradwohl, G., Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord (2003) Dev Biol, 253, pp. 84-98
• Lehnardt, S., Lachance, C., Patrizi, S., Lefebvre, S., Follett, P.L., Jensen, F.E., Rosenberg, P.A., Vartanian, T., The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS (2002) J Neurosci, 22, pp. 2478-2486
• Lehnardt, S., Massillon, L., Follett, P., Jensen, F.E., Ratan, R., Rosenberg, P.A., Volpe, J.J., Vartanian, T., Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway (2003) Proc Natl Acad Sci USA, 100, pp. 8514-8519
• Lehnardt, S., Schott, E., Trimbuch, T., Laubisch, D., Krueger, C., Wulczyn, G., Nitsch, R., Weber, J.R., A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS (2008) J Neurosci, 28, pp. 2320-2331
• Leitner, H., Influence of neurosteroids on the pathogenesis of multiple sclerosis (2010) Med Hypotheses, 75, pp. 229-234
• Leonelli, E., Bianchi, R., Cavaletti, G., Caruso, D., Crippa, D., Garcia-Segura, L.M., Lauria, G., Melcangi, R.C., Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis (2007) Neuroscience, 144, pp. 1293-1304
• Ligon, K.L., Fancy, S.P., Franklin, R.J., Rowitch, D.H., Olig gene function in CNS development and disease (2006) Glia, 54, pp. 1-10
• Livak, K.J., Schmittgen, T.D., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method (2001) Methods, 25, pp. 402-408
• MacEwan, D.J., TNF receptor subtype signalling: differences and cellular consequences (2002) Cell Signal, 14, pp. 477-492
• Marin-Husstege, M., Muggironi, M., Raban, D., Skoff, R.P., Casaccia-Bonnefil, P., Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones (2004) Dev Neurosci, 26, pp. 245-254
• Matute, C., Perez-Cerda, F., Multiple sclerosis: novel perspectives on newly forming lesions (2005) Trends Neurosci, 28, pp. 173-175
• Mc Guire, C., Beyaert, R., van Loo, G., Death receptor signalling in central nervous system inflammation and demyelination (2011) Trends Neurosci, 34, pp. 619-628
• McDonald, J.W., Belegu, V., Demyelination and remyelination after spinal cord injury (2006) J Neurotrauma, 23, pp. 345-359
• McQualter, J.L., Bernard, C.C., Multiple sclerosis: a battle between destruction and repair (2007) J Neurochem, 100, pp. 295-306
• Melcangi, R.C., Magnaghi, V., Cavarretta, I., Zucchi, I., Bovolin, P., D'Urso, D., Martini, L., Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action (1999) J Neurosci Res, 56, pp. 349-357
• Melcangi, R.C., Ballabio, M., Cavarretta, I., Gonzalez, L.C., Leonelli, E., Veiga, S., Martini, L., Magnaghi, V., Effects of neuroactive steroids on myelin of peripheral nervous system (2003) J Steroid Biochem Mol Biol, 85, pp. 323-327
• Mensah-Nyagan, A.G., Meyer, L., Schaeffer, V., Kibaly, C., Patte-Mensah, C., Evidence for a key role of steroids in the modulation of pain (2009) Psychoneuroendocrinology, 34 (SUPPL. 1), pp. S169-177
• Miyaura, H., Iwata, M., Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids (2002) J Immunol, 168, pp. 1087-1094
• Morales, L.B., Loo, K.K., Liu, H.B., Peterson, C., Tiwari-Woodruff, S., Voskuhl, R.R., Treatment with an estrogen receptor alpha ligand is neuroprotective in experimental autoimmune encephalomyelitis (2006) J Neurosci, 26, pp. 6823-6833
• Muller, E., Kerschbaum, H.H., Progesterone and its metabolites 5-dihydroprogesterone and 5-3-tetrahydroprogesterone decrease LPS-induced NO release in the murine microglial cell line, BV-2 (2006) Neuro Endocrinol Lett, 27, pp. 675-678
• Noorbakhsh, F., Ellestad, K.K., Maingat, F., Warren, K.G., Han, M.H., Steinman, L., Baker, G.B., Power, C., Impaired neurosteroid synthesis in multiple sclerosis (2011) Brain, 134, pp. 2703-2721
• Offner, H., Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis (2004) J Neurosci Res, 78, pp. 603-624
• Okun, E., Griffioen, K.J., Mattson, M.P., Toll-like receptor signaling in neural plasticity and disease (2011) Trends Neurosci, 34, pp. 269-281
• Palaszynski, K.M., Liu, H., Loo, K.K., Voskuhl, R.R., Estriol treatment ameliorates disease in males with experimental autoimmune encephalomyelitis: implications for multiple sclerosis (2004) J Neuroimmunol, 149, pp. 84-89
• Pettus, E.H., Wright, D.W., Stein, D.G., Hoffman, S.W., Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury (2005) Brain Res, 1049, pp. 112-119
• Piccinni, M.P., Giudizi, M.G., Biagiotti, R., Beloni, L., Giannarini, L., Sampognaro, S., Parronchi, P., Livi, C., Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones (1995) J Immunol, 155, pp. 128-133
• Qi, Y., Cai, J., Wu, Y., Lee, J., Fu, H., Rao, M., Sussel, L., Qiu, M., Control of oligodendrocyte differentiation by the NKx2.2 homeodomain transcription factor (2001) Development, 128, pp. 2723-2733
• Roy, A., Fung, Y.K., Liu, X., Pahan, K., Up-regulation of microglial CD11b expression by nitric oxide (2006) J Biol Chem, 281, pp. 14971-14980
• Schumacher, M., Guennoun, R., Stein, D.G., De Nicola, A.F., Progesterone: therapeutic opportunities for neuroprotection and myelin repair (2007) Pharmacol Ther, 116, pp. 77-106
• Selmaj, K., Raine, C.S., Cross, A.H., Anti-tumor necrosis factor therapy abrogates autoimmune demyelination (1991) Ann Neurol, 30, pp. 694-700
• Stein, D.G., Progesterone exerts neuroprotective effects after brain injury (2008) Brain Res Rev, 57, pp. 386-397
• Su, L., Sun, Y., Ma, F., Lu, P., Huang, H., Zhou, J.C., Progesterone inhibits Toll-like receptor 4-mediated innate immune response in macrophages by suppressing NF-kappaB activation and enhancing SOCS1 expression (2009) Immunol Lett, 125, pp. 151-155
• Su, Z., Yuan, Y., Chen, J., Zhu, Y., Qiu, Y., Zhu, F., Huang, A., He, C., Reactive astrocytes inhibit the survival and differentiation of oligodendrocyte precursor cells by secreted TNF-alpha (2011) J Neurotrauma, 28, pp. 1089-1100
• Sun, D., Zhang, Y., Wei, B., Peiper, S.C., Shao, H., Kaplan, H.J., Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules (2003) Int Immunol, 15, pp. 261-268
• Teuscher, C., Hickey, W.F., Korngold, R., An analysis of the role of tumor necrosis factor in the phenotypic expression of actively induced experimental allergic orchitis and experimental allergic encephalomyelitis (1990) Clin Immunol Immunopathol, 54, pp. 442-453
• Trapp, B.D., Nave, K.A., Multiple sclerosis: an immune or neurodegenerative disorder? (2008) Annu Rev Neurosci, 31, pp. 247-269
• Yates, M.A., Li, Y., Chlebeck, P., Proctor, T., Vandenbark, A.A., Offner, H., Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis (2010) J Neuroimmunol, 220, pp. 136-139
• Yu, H.J., Fei, J., Chen, X.S., Cai, Q.Y., Liu, H.L., Liu, G.D., Yao, Z.X., Progesterone attenuates neurological behavioral deficits of experimental autoimmune encephalomyelitis through remyelination with nucleus-sublocalized Olig1 protein (2010) Neurosci Lett, 476, pp. 42-45

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------