logo biblio digital exactas
logo twitter logo instagram logo whatsapp logo mail

Navegar

Colección

Datos Estadísticas

Lista de

Protein Structure, Tertiary
91
"Synthesis and activity evaluation of a series of cholanamides as modulators of the liver X receptors" (2018) Martínez, M.D.;Ghini, A.A.;Dansey, M.V. (...)Burton, G. Bioorganic and Medicinal Chemistry. 26(5):1092-1101
"The PKA regulatory subunit from yeast forms a homotetramer: Low-resolution structure of the N-terminal oligomerization domain" (2016) González Bardeci, N.;Caramelo, J.J.;Blumenthal, D.K. (...)Moreno, S. Journal of Structural Biology. 193(2):141-154
"Repeat proteins challenge the concept of structural domains" (2015) Espada, R.;Parra, R.G.;Sippl, M.J. (...)Ferreiro, D.U. Biochemical Society Transactions. 43:844-849
"Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi" (2015) García Liñares, G.;Antonela Zígolo, M.;Simonetti, L. (...)Baldessari, A. Bioorganic and Medicinal Chemistry. 23(15):4804-4814
"Exploring the molecular basis of action of ring D aromatic steroidal antiestrogens" (2015) Alvarez, L.D.; Veleiro, A.S.; Burton, G. Proteins: Structure, Function and Bioinformatics. 83(7):1297-1306
"Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin" (2015) Boron, I.;Capece, L.;Pennacchietti, F. (...)Nadra, A.D. Biochimica et Biophysica Acta - General Subjects. 1850(1):169-177
"Efficient calculation of enzyme reaction free energy profiles using a hybrid differential relaxation algorithm: Application to mycobacterial zinc hydrolases" (2015) Romero, J.M.;Martin, M.;Ramirez, C.L. (...)Karabencheva-Christova T. Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions, 2015. 100:33-65
"Molecular chaperone activity and biological regulatory actions of the TPR-domain immunophilins FKBP51 and FKBP52" (2014) Erlejman, A.G.;Lagadari, M.;Harris, D.C. (...)Galigniana, M.D. Current Protein and Peptide Science. 15(3):205-215
"Structural basis of redox-dependent modulation of galectin-1 dynamics and function" (2014) Guardia, C.M.;Caramelo, J.J.;Trujillo, M. (...)Rabinovich, G.A. Glycobiology. 24(5):428-441
"TuberQ: A Mycobacterium tuberculosis protein druggability database" (2014) Radusky, L.;Defelipe, L.A.;Lanzarotti, E. (...)Turjanski, A.G. Database. 2014
"Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain" (2014) Aran, M.;Smal, C.;Pellizza, L. (...)Cicero, D.O. Proteins: Structure, Function and Bioinformatics. 82(11):3062-3078
"Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys" (2014) Mazzitelli, L.R.; Adamo, H.P. Journal of Biological Chemistry. 289(15):10761-10768
"Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor" (2014) Presman, D.M.;Ogara, M.F.;Stortz, M. (...)Pecci, A. PLoS Biology. 12(3)
"Ligand uptake modulation by internal water molecules and hydrophobic cavities in hemoglobins" (2014) Bustamante, J.P.;Abbruzzetti, S.;Marcelli, A. (...)Viappiani, C. Journal of Physical Chemistry B. 118(5):1234-1245
"Underlying Thermodynamics of pH-Dependent Allostery" (2014) Di Russo, N.V.; Martí, M.A.; Roitberg, A.E. Journal of Physical Chemistry B. 118(45):12818-12826
"Folding of a cyclin box: Linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor ab pocket domain" (2013) Chemes, L.B.; Noval, M.G.; Sánchez, I.E.; De Prat-Gay, G. Journal of Biological Chemistry. 288(26):18923-18938
"Phosphate mediated adsorption and electron transfer of cytochrome c. A time-resolved SERR spectroelectrochemical study" (2013) Capdevila, D.A.; Marmisollé, W.A.; Williams, F.J.; Murgida, D.H. Physical Chemistry Chemical Physics. 15(15):5386-5394
"Solvent structure improves docking prediction in lectin-carbohydrate complexes" (2013) Gauto, D.F.;Petruk, A.A.;Modenutti, C.P. (...)Martí, M.A. Glycobiology. 23(2):241-258
"RapA2 is a calcium-binding lectin composed of two highly conserved cadherin-like domains that specifically recognize rhizobium leguminosarum acidic exopolysaccharides" (2013) Abdian, P.L.; Caramelo, J.J.; Ausmees, N.; Zorreguieta, A. Journal of Biological Chemistry. 288(4):2893-2904
"RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity" (2013) Druker, J.;Liberman, A.C.;Antunica-Noguerol, M. (...)Arzta, E. Molecular and Cellular Biology. 33(11):2116-2127
"Detecting repetitions and periodicities in proteins by tiling the structural space" (2013) Parra, R.G.;Espada, R.;Sánchez, I.E. (...)Ferreiro, D.U. Journal of Physical Chemistry B. 117(42):12887-12897
"Binding of modulators to mouse and human multidrug resistance P-glycoprotein. A computational study" (2013) Jara, G.E.; Vera, D.M.A.; Pierini, A.B. Journal of Molecular Graphics and Modelling. 46:10-21
"Proteasome-mediated turnover of arabidopsis MED25 is coupled to the activation of FLOWERING LOCUS T transcription" (2012) Iñigo, S.; Giraldez, A.N.; Chory, J.; Cerdán, P.D. Plant Physiology. 160(3):1662-1673
"Protein frustratometer: A tool to localize energetic frustration in protein molecules" (2012) Jenik, M.;Parra, R.G.;Radusky, L.G. (...)Ferreiro, D.U. Nucleic Acids Research. 40(W1):W348-W351
"Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription" (2012) Moiola, C.;De Luca, P.;Cotignola, J. (...)De Siervi, A. Cellular Physiology and Biochemistry. 30(3):596-608
"Protein Stability and Dynamics Modulation: The Case of Human Frataxin" (2012) Roman, E.A.;Faraj, S.E.;Gallo, M. (...)Santos, J. PLoS ONE. 7(9)
"Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein" (2012) Chemes, L.B.;Glavina, J.;Alonso, L.G. (...)Sánchez, I.E. PLoS ONE. 7(10)
"Evolution of linear motifs within the papillomavirus E7 oncoprotein" (2012) Chemes, L.B.;Glavina, J.;Faivovich, J. (...)Sánchez, I.E. Journal of Molecular Biology. 422(3):336-346
"BmaC, a novel autotransporter of Brucella suis, is involved in bacterial adhesion to host cells" (2012) Posadas, D.M.;Ruiz-Ranwez, V.;Bonomi, H.R. (...)Zorreguieta, A. Cellular Microbiology. 14(6):965-982
"Oligomerization studies show that the kinase domain of the tomato pollen receptor kinase LePRK2 is necessary for interaction with LePRK1" (2012) Salem, T.M.;Barberini, M.L.;Wengier, D.L. (...)Muschietti, J. Plant Physiology and Biochemistry. 53:40-45
"Accumulation pattern of dehydrins during sugarcane (var. SP80.3280) somatic embryogenesis" (2012) Burrieza, H.P.;López-Fernández, M.P.;Chiquieri, T.B. (...)Maldonado, S. Plant Cell Reports. 31(12):2139-2149
"Light regulates attachment, exopolysaccharide production, and nodulation in Rhizobium leguminosarum through a LOV-histidine kinase photoreceptor" (2012) Bonomi, H.R.;Posadas, D.M.;Paris, G. (...)Goldbaum, F.A. Proceedings of the National Academy of Sciences of the United States of America. 109(30):12135-12140
"Management of cytoskeleton architecture by molecular chaperones and immunophilins" (2011) Quintá, H.R.;Galigniana, N.M.;Erlejman, A.G. (...)Galigniana, M.D. Cellular Signalling. 23(12):1907-1920
"Ligand migration in the apolar tunnel of Cerebratulus lacteus mini-hemoglobin" (2011) Pesce, A.;Nardini, M.;Dewilde, S. (...)Olson, J.S. Journal of Biological Chemistry. 286(7):5347-5358
"P38γ activation triggers dynamical changes in allosteric docking sites" (2011) Rodriguez Limardo, R.G.;Ferreiro, D.N.;Roitberg, A.E. (...)Turjanski, A.G. Biochemistry. 50(8):1384-1395
"An integrated computational analysis of the structure, dynamics, and ligand binding interactions of the human galectin network" (2011) Guardia, C.M.A.;Gauto, D.F.;Di Lella, S. (...)Estrin, D.A. Journal of Chemical Information and Modeling. 51(8):1918-1930
"Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi" (2011) Schoijet, A.C.;Miranda, K.;Medeiros, L.C.S. (...)Alonso, G.D. Molecular Microbiology. 79(1):50-62
"On the role of frustration in the energy landscapes of allosteric proteins" (2011) Ferreiro, D.U.; Hegler, J.A.; Komives, E.A.; Wolynes, P.G. Proceedings of the National Academy of Sciences of the United States of America. 108(9):3499-3503
"The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress" (2011) Gallo, L.I.; Lagadari, M.; Piwien-Pilipuk, G.; Galigniana, M.D. Journal of Biological Chemistry. 286(34):30152-30160
"Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo" (2011) Stigliano, I.D.;Alculumbre, S.G.;Labriola, C.A. (...)D'Alessio, C. Molecular Biology of the Cell. 22(11):1810-1823
"Electron transfer dynamics of Rhodothermus marinus caa 3 cytochrome c domains on biomimetic films" (2011) Molinas, M.F.;De Candia, A.;Szajnman, S.H. (...)Murgida, D.H. Physical Chemistry Chemical Physics. 13(40):18088-18098
"Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands" (2010) Veleiro, A.S.; Alvarez, L.D.; Eduardo, S.L.; Burton, G. ChemMedChem. 5(5):649-659
"The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events" (2010) Galigniana, M.D.;Erlejman, A.G.;Monte, M. (...)Piwien-Pilipuk, G. Molecular and Cellular Biology. 30(5):1285-1298
"Thermodynamics of cooperative DNA recognition at a replication origin and transcription regulatory site" (2010) Dellarole, M.; Sánchez, I.E.; De Prat Gay, G. Biochemistry. 49(48):10277-10286
"Copper-transfer mechanism from the human chaperone Atox1 to a metal-binding domain of wilson disease protein" (2010) Rodriguez-Granillo, A.; Crespo, A.; Estrin, D.A.; Wittung-Stafshede, P. Journal of Physical Chemistry B. 114(10):3698-3706
"The structure of calreticulin C-terminal domain is modulated by physiological variations of calcium concentration" (2010) Giraldo, A.M.V.;Medus, M.L.;Lebrero, M.G. (...)Caramelo, J.J. Journal of Biological Chemistry. 285(7):4544-4553
"Molecular basis of coupled protein and electron transfer dynamics of cytochrome c in biomimetic complexes" (2010) Alvarez-Paggi, D.;Martín, D.F.;Debiase, P.M. (...)Murgida, D.H. Journal of the American Chemical Society. 132(16):5769-5778
"The yeast endocytic protein Epsin 2 functions in a cell-division signaling pathway" (2009) Mukherjee, D.;Coon, B.G.;Edwards III, D.F. (...)Aguilar, R.C. Journal of Cell Science. 122(14):2453-2463
"Mammalian Staufen 1 is recruited to stress granules and impairs their assembly" (2009) Thomas, M.G.;Martinez Tosar, L.J.;Desbats, M.A. (...)Boccaccio, G.L. Journal of Cell Science. 122(4):563-573
"High pressure reveals structural determinants for globin hexacoordination: neuroglobin and myoglobin cases." (2009) Capece, L.;Marti, M.A.;Bidon-Chanal, A. (...)Estrin, D.A. Proteins. 75(4):885-894
"Glucosidase II β subunit modulates N-glycan trimming in fission yeasts and mammals" (2009) Stigliano, I.D.;Caramelo, J.J.;Labriola, C.A. (...)D'Alessio, C. Molecular Biology of the Cell. 20(17):3974-3984
"Functional characterization and protein-protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1" (2009) Vazquez, M.P.;Mualem, D.;Bercovich, N. (...)Levin, M.J. Molecular and Biochemical Parasitology. 164(2):137-146
"The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins" (2009) Smal, C.;Wetzler, D.E.;Dantur, K.I. (...)De Prat-Gay, G. Biochemistry. 48(50):11939-11949
"Identification of an autoinhibitory mechanism that restricts C1 domain-mediated activation of the Rac-GAP α2-chimaerin" (2008) Colón-González, F.; Leskow, F.C.; Kazanietz, M.G. Journal of Biological Chemistry. 283(50):35247-35257
"Bond or cage effect: How nitrophorins transport and release nitric oxide" (2008) Martí, M.A.; González Lebrero, M.C.; Roitberg, A.E.; Estrin, D.A. Journal of the American Chemical Society. 130(5):1611-1618
"A splicing regulator promotes transcriptional elongation" (2008) Fededa, J.P.; Kornblihtt, A.R. Nature Structural and Molecular Biology. 15(8):779-781
"Sulfates are main targets of immune responses to cruzipain and are involved in heart damage in BALB/c immunized mice" (2008) Acosta, D.M.;Arnaiz, M.R.;Esteva, M.I. (...)Duschak, V.G. International Immunology. 20(4):461-470
"Trapping and characterization of a reaction intermediate in carbapenem hydrolysis by B. cereus metallo-β-lactamase" (2008) Tioni, M.F.;Llarrull, L.I.;Poeylaut-Palena, A.A. (...)Vila, A.J. Journal of the American Chemical Society. 130(47):15852-15863
"Mechanism of product release in NO detoxification from Mycobacterium tuberculosis truncated hemoglobin N" (2008) Martí, M.A.;Bidon-Chanal, A.;Crespo, A. (...)Estrin, D.A. Journal of the American Chemical Society. 130(5):1688-1693
"A novel activating effect of the regulatory subunit of protein kinase A on catalytic subunit activity" (2008) Rinaldi, J.; Ocampo, J.; Rossi, S.; Moreno, S. Archives of Biochemistry and Biophysics. 480(2):95-103
"PKA from Mucor circinelloides: Model to study the role of linker I in the interaction between R and C subunits" (2007) Ocampo, J.; Moreno, S.; Rossi, S. Biochemical and Biophysical Research Communications. 362(3):721-726
"Mapping of the protein-binding interface between splicing factors SF3b155 and p14 of Trypanosoma cruzi" (2007) Avila, M.L.;Bercovich, N.;Westergaard, G. (...)Vázquez, M.P. Biochemical and Biophysical Research Communications. 364(1):26-32
"RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20" (2006) De La Mata, M.; Kornblihtt, A.R. Nature Structural and Molecular Biology. 13(11):973-980
"Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins" (2006) Aguilar, R.C.;Longhi, S.A.;Shaw, J.D. (...)Wendland, B. Proceedings of the National Academy of Sciences of the United States of America. 103(11):4116-4121
"Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes" (2005) Thomas, M.G.;Tosar, L.J.M.;Loschi, M. (...)Boccaccio, G.L. Molecular Biology of the Cell. 16(1):405-420
"Kinase partner protein interacts with the LePRK1 and LePRK2 receptor kinases and plays a role in polarized pollen tube growth" (2005) Kaothien, P.;Sung, H.O.;Shuai, B. (...)McCormick, S. Plant Journal. 42(4):492-503
"Free energy contributions to direct readout of a DNA sequence" (2005) Ferreiro, D.U.; Dellarole, M.; Nadra, A.D.; De Prat-Gay, G. Journal of Biological Chemistry. 280(37):32480-32484
"Identification and characterisation of the α and β subunits of succinyl CoA ligase of tomato" (2005) Studart-Guimarães, C.;Gibon, Y.;Frankel, N. (...)Carrari, F. Plant Molecular Biology. 59(5):781-791
"The Anp32 family of proteins containing leucine-rich repeats" (2005) Matilla, A.; Radrizzani, M. Cerebellum. 4(1):7-18
"Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus" (2004) Galigniana, M.D.;Harrell, J.M.;O'Hagen, H.M. (...)Pratt, W.B. Journal of Biological Chemistry. 279(21):22483-22489
"Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver" (2004) Chang, M.-L.;Chen, J.-C.;Alonso, C.R. (...)Bissell, D.M. Proceedings of the National Academy of Sciences of the United States of America. 101(52):18093-18098
"Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo" (2004) Agustí, R.;París, G.;Ratier, L. (...)de Lederkremer, R.M. Glycobiology. 14(7):659-670
"Ab initio study of NMR 15N chemical shift differences induced by Ca2+ binding to EF-hand proteins" (2004) Biekofsky, R.R.;Turjanski, A.G.;Estrin, D.A. (...)Pastore, A. Biochemistry. 43(21):6554-6564
"Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex" (2004) Galigniana, M.D.; Morishima, Y.; Gallay, P.A.; Pratt, W.B. Journal of Biological Chemistry. 279(53):55754-55759
"Influence of Polymerase II Processivity on Alternative Splicing Depends on Splice Site Strength" (2003) Nogués, G.; Muñoz, M.J.; Kornblihtt, A.R. Journal of Biological Chemistry. 278(52):52166-52171
"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746
"Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases" (2003) Portal, D.;Lobo, G.S.;Kadener, S. (...)Torres, H.N. Molecular and Biochemical Parasitology. 127(1):9-21
"Human p8 Is a HMG-I/Y-like Protein with DNA Binding Activity Enhanced by Phosphorylation" (2001) Encinar, J.A.;Mallo, G.V.;Mizyrycki, C. (...)Iovanna, J.L. Journal of Biological Chemistry. 276(4):2742-2751
"Structural, functional and immunological studies on a polymeric bacterial protein" (2000) Baldi, P.C.;Velikovsky, C.A.;Braden, B.C. (...)Goldbaum, F.A. Brazilian Journal of Medical and Biological Research. 33(7):741-747