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mitogen activated protein kinase
99
"Lead enhancement of 3T3-L1 fibroblasts differentiation to adipocytes involves ERK, C/EBPβ and PPARγ activation" (2018) Martini, C.N.;Gabrielli, M.;Bonifacino, G. (...)Vila, M.D.C. Molecular and Cellular Biochemistry. 437(1-2):37-44
"Influence of ochratoxin A on adaptation of Penicillium nordicum on a NaCl-rich dry-cured ham-based medium" (2018) Delgado, J.; da Cruz Cabral, L.; Rodríguez, M.; Rodríguez, A. International Journal of Food Microbiology. 272:22-28
"POLAR-guided signalling complex assembly and localization drive asymmetric cell division" (2018) Houbaert, A.;Zhang, C.;Tiwari, M. (...)Russinova, E. Nature. 563(7732):574-578
"CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5" (2018) Repetto, M.V.;Winters, M.J.;Bush, A. (...)Colman-Lerner, A. Molecular Cell. 69(6):938-952.e6
"CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5" (2018) Repetto, M.V.;Winters, M.J.;Bush, A. (...)Colman-Lerner, A. Molecular Cell. 69(6):938-952.e6
"Single-cell profiling screen identifies microtubule-dependent reduction of variability in signaling" (2018) Pesce, C.G.;Zdraljevic, S.;Peria, W.J. (...)Brent, R. Molecular Systems Biology. 14(4)
"MCAM knockdown impairs PPARγ expression and 3T3-L1 fibroblasts differentiation to adipocytes" (2018) Gabrielli, M.;Romero, D.G.;Martini, C.N. (...)Vila, M.D.C. Molecular and Cellular Biochemistry. 448(1-2):299-309
"Tankyrase inhibition regulates corpus luteum development and luteal function in gonadotropin-treated rats" (2017) Accialini, P.;Irusta, G.;Bechis, A. (...)Tesone, M. Molecular Reproduction and Development. 84(8):719-730
"Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations" (2017) Altszyler, E.; Ventura, A.C.; Colman-Lerner, A.; Chernomoretz, A. PLoS ONE. 12(6)
"Human renal adipose tissue induces the invasion and progression of renal cell carcinoma" (2017) Campo-Verde-Arbocco, F.;López-Laur, J.D.;Romeo, L.R. (...)Creydt, V.P. Oncotarget. 8(55):94223-94234
"MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a β-Arrestin2-Dependent Pathway" (2017) Cerniello, F.M.;Carretero, O.A.;Carbajosa, N.A.L. (...)Gironacci, M.M. Hypertension. 70(5):982-989
"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139
"Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors" (2016) Michelini, F.M.;Bueno, C.A.;Molinari, A.M. (...)Ramírez, J.A. Biochimica et Biophysica Acta - General Subjects. 1860(1):129-139
"N-acetylcysteine inhibits lipid accumulation in mouse embryonic adipocytes" (2016) Pieralisi, A.;Martini, C.;Soto, D. (...)Guerra, L.N. Redox Biology. 9:39-44
"Reconsolidation-induced memory persistence: Participation of late phase hippocampal ERK activation" (2016) Krawczyk, M.C.;Navarro, N.;Blake, M.G. (...)Boccia, M.M. Neurobiology of Learning and Memory. 133:79-88
"Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549" (2016) Silva, I.T.;Geller, F.C.;Persich, L. (...)Simões, C.M.O. Investigational New Drugs. 34(2):139-148
"Heteromerization between the Bradykinin B2 Receptor and the Angiotensin-(1-7) Mas Receptor: Functional Consequences" (2016) Cerrato, B.D.;Carretero, O.A.;Janic, B. (...)Gironacci, M.M. Hypertension. 68(4):1039-1048
"Heteromerization between the Bradykinin B2 Receptor and the Angiotensin-(1-7) Mas Receptor: Functional Consequences" (2016) Cerrato, B.D.;Carretero, O.A.;Janic, B. (...)Gironacci, M.M. Hypertension. 68(4):1039-1048
"Mechanisms involved in p53 downregulation by leptin in trophoblastic cells" (2015) Toro, A.R.;Pérez-Pérez, A.;Corrales Gutiérrez, I. (...)Varone, C.L. Placenta. 36(11):1266-1275
"In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B" (2015) Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. PLoS ONE. 10(2)
"MAPK's networks and their capacity for multistationarity due to toric steady states" (2015) Pérez Millán, M.; Turjanski, A.G. Mathematical Biosciences. 262:125-137
"Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway" (2015) Bueno, C.A.;Michelini, F.M.;Pertino, M.W. (...)Alché, L.E. Medical Microbiology and Immunology. 204(5):575-584
"Uncovering distinct protein-network topologies in heterogeneous cell populations" (2015) Wieczorek, J.;Malik-Sheriff, R.S.;Fermin, Y. (...)Ickstadt, K. BMC Systems Biology. 9(1)
"Uncovering distinct protein-network topologies in heterogeneous cell populations" (2015) Wieczorek, J.;Malik-Sheriff, R.S.;Fermin, Y. (...)Ickstadt, K. BMC Systems Biology
"Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice" (2014) González, B.;Raineri, M.;Cadet, J.L. (...)Bisagno, V. Neuropharmacology. 87:188-197
"Raf/MEK/ERK pathway activation is required for Junín virus replication" (2014) Rodríguez, M.E.;Brunetti, J.E.;Wachsman, M.B. (...)Castilla, V. Journal of General Virology. 95(PART 4):799-805
"Epigenetic mechanisms and memory strength: A comparative study" (2014) Federman, N.;Zalcman, G.;de la Fuente, V. (...)Romano, A. Journal of Physiology Paris. 108(4-6):278-285
"Evaluation of cytotoxic activity of cucurbitacins and their semisynthetic derivatives" (2014) Da-Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. Vitae. 21:S25
"Phosphorylation of mitogen-activated protein kinases contributes to interferon γ production in response to mycobacterium tuberculosis" (2013) Pasquinelli, V.;Rovetta, A.I.;Alvarez, I.B. (...)García, V.E. Journal of Infectious Diseases. 207(2):340-350
"Pea3 transcription factor family members Etv4 and Etv5 mediate retrograde signaling and axonal growth of DRG sensory neurons in response to NGF" (2013) Fontanet, P.;Irala, D.;Alsina, F.C. (...)Ledda, F. Journal of Neuroscience. 33(40):15940-15951
"Parasite infections in multiple sclerosis modulate immune responses through a retinoic acid-dependent pathway" (2013) Correale, J.; Farez, M.F. Journal of Immunology. 191(7):3827-3837
"Quantitative measurement of protein relocalization in live cells" (2013) Bush, A.; Colman-Lerner, A. Biophysical Journal. 104(3):727-736
"Pheromone-induced morphogenesis improves osmoadaptation capacity by activating the HOG MAPK pathway" (2013) Baltanás, R.;Bush, A.;Couto, A. (...)Colman-Lerner, A. Science Signaling. 6(272)
"Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha" (2012) Gambino, Y.P.;Pérez Pérez, A.;Dueñas, J.L. (...)Varone, C.L. Biochimica et Biophysica Acta - Molecular Cell Research. 1823(4):900-910
"The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells" (2012) Maymó, J.L.;Pérez Pérez, A.;Maskin, B. (...)Varone, C.L. PLoS ONE. 7(10)
"New insights into melatonin/CRH signaling in hamster Leydig cells" (2012) Rossi, S.P.;Matzkin, M.E.;Terradas, C. (...)Frungieri, M.B. General and Comparative Endocrinology. 178(1):153-163
"Underlying mechanisms of cAMP- and glucocorticoid-mediated inhibition of FasL expression in activation-induced cell death" (2012) Liberman, A.C.;Refojo, D.;Antunica-Noguerol, M. (...)Arzt, E. Molecular Immunology. 50(4):220-235
"In vitro antiviral activity of dehydroepiandrosterone, 17 synthetic analogs and ERK modulators against herpes simplex virus type 1" (2012) Torres, N.I.;Castilla, V.;Bruttomesso, A.C. (...)Wachsman, M.B. Antiviral Research. 95(1):37-48
"Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer" (2012) Rabinovich, G.; Croci, D.O. Immunity. 36(3):322-335
"The crystal structure of the MAP kinase LmaMPK10 from leishmania major reveals parasite-specific features and regulatory mechanisms" (2012) Horjales, S.;Schmidt-Arras, D.;Limardo, R.R. (...)Buschiazzo, A. Structure. 20(10):1649-1660
"Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production" (2011) Ladelfa, M.F.; Toledo, M.F.; Laiseca, J.E.; Monte, M. Antioxidants and Redox Signaling. 15(6):1749-1761
"C/EBP2 mediates growth hormone-regulated expression of multiple target genes" (2011) Cui, T.X.;Lin, G.;Lapensee, C.R. (...)Schwartz, J. Molecular Endocrinology. 25(4):681-693
"When galectins recognize glycans: From biochemistry to physiology and back again" (2011) Di Lella, S.;Sundblad, V.;Cerliani, J.P. (...)Rabinovich, G.A. Biochemistry. 50(37):7842-7857
"Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells" (2011) Sánchez-Jiménez, F.;Pérez-Pérez, A.;González-Yanes, C. (...)Sánchez-Margalet, V. Human Reproduction. 26(9):2306-2315
"Characterization of the B-Raf interactome in mouse hippocampal neuronal cells" (2011) Bonfiglio, J.J.;Maccarrone, G.;Rewerts, C. (...)Silberstein, S. Journal of Proteomics. 74(2):186-198
"Classical membrane progesterone receptors in murine mammary carcinomas: Agonistic effects of progestins and RU-486 mediating rapid non-genomic effects" (2011) Bottino, M.C.;Cerliani, J.P.;Rojas, P. (...)Lanari, C. Breast Cancer Research and Treatment. 126(3):621-636
"Review: Leptin gene expression in the placenta - Regulation of a key hormone in trophoblast proliferation and survival" (2011) Maymó, J.L.;Pérez Pérez, A.;Gambino, Y. (...)Varone, C.L. Placenta. 32(SUPPL 2):S146-S153
"The corticotropin-releasing hormone network and the hypothalamic-pituitary- adrenal axis: Molecular and cellular mechanisms involved" (2011) Bonfiglio, J.J.;Inda, C.;Refojo, D. (...)Silberstein, S. Neuroendocrinology. 94(1):12-20
"Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range" (2011) Thomson, T.M.;Benjamin, K.R.;Bush, A. (...)Brent, R. Proceedings of the National Academy of Sciences of the United States of America. 108(50):20265-20270
"P38γ activation triggers dynamical changes in allosteric docking sites" (2011) Rodriguez Limardo, R.G.;Ferreiro, D.N.;Roitberg, A.E. (...)Turjanski, A.G. Biochemistry. 50(8):1384-1395
"Direct survival role of vascular endothelial growth factor (VEGF) on rat ovarian follicular cells" (2010) Irusta, G.; Abramovich, D.; Parborell, F.; Tesone, M. Molecular and Cellular Endocrinology. 325(1-2):93-100
"17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions" (2010) Gambino, Y.P.;Maymó, J.L.;Pérez-Pérez, A. (...)Varone, C.L. Biology of Reproduction. 83(1):42-51
"17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions" (2010) Gambino, Y.P.;Maymó, J.L.;Pérez-Pérez, A. (...)Varone, C.L. Biology of Reproduction. 83(1):42-51
"c-Jun regulates phosphoinositide-dependent kinase 1 transcription: Implication for Akt and protein kinase C activities melanoma tumorigenesis" (2010) Lopez-Bergami, P.;Kim, H.;Dewing, A. (...)Ronai, Z. Journal of Biological Chemistry. 285(2):903-913
"Molecular mechanisms of glucocorticoids action: From basic research to clinical implications" (2010) Liberman, A.C.;Castro, C.N.;Noguerol, M.A. (...)Arzt, E. Current Immunology Reviews. 6(4):371-380
"Disruptive effect of epigallocatechin-3-gallate on the proliferation/ apoptosis balance in the olfactory epithelium" (2010) Jungblut, L.D.; Paz, D.A.; Pozzi, A.G. Journal of Epithelial Biology and Pharmacology. 3:20-25
"Chromatin and alternative splicing" (2010) Alló, M.;Schor, I.E.;Muñoz, M.J. (...)Kornblihtt, A.R. Cold Spring Harbor Symposia on Quantitative Biology. 75:103-111
"MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells" (2010) Pérez-Pérez, A.;Gambino, Y.;Maymó, J. (...)Sánchez-Margalet, V. Biochemical and Biophysical Research Communications. 396(4):956-960
"Immunology, signal transduction, and behavior in hypothalamic-pituitary- adrenal axis-related genetic mouse models" (2009) Silberstein, S.;Vogl, A.M.;Bonfiglio, J.J. (...)Refojo, D. Annals of the New York Academy of Sciences. 1153:120-130
"How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study" (2009) Turjanski, A.G.; Hummer, G.; Gutkind, J.S. Journal of the American Chemical Society. 131(17):6141-6148
"How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study" (2009) Turjanski, A.G.; Hummer, G.; Gutkind, J.S. Journal of the American Chemical Society. 131(17):6141-6148
"Dok-4 is a novel negative regulator of T cell activation" (2009) Gérard, A.;Ghiotto, M.;Fos, C. (...)Nunès, J.A. Journal of Immunology. 182(12):7681-7689
"Up-Regulation of placental leptin by human chorionic gonadotropin" (2009) Maymó, J.L.;Pérez, A.P.;Sánchez-Margalet, V. (...)Varone, C.L. Endocrinology. 150(1):304-313
"Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells" (2009) Pérez-Pérez, A.;Julieta Maymo, Y.;Gambino, É. (...)Sánchez-Margalet, V. Biology of Reproduction. 81(5):826-832
"Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells" (2009) Pérez-Pérez, A.;Julieta Maymo, Y.;Gambino, É. (...)Sánchez-Margalet, V. Biology of Reproduction. 81(5):826-832
"GM-CSF enhances a CpG-independent pathway of neutrophil activation triggered by bacterial DNA" (2008) Bass, J.I.F.;Alvarez, M.E.;Gabelloni, M.L. (...)Trevani, A.S. Molecular Immunology. 46(1):37-44
"The Alpha Project: A model system for systems biology research" (2008) Yu, R.C.;Resnekov, O.;Abola, A.P. (...)Brent, R. IET Systems Biology. 2(5):222-233
"Negative feedback that improves information transmission in yeast signalling" (2008) Yu, R.C.;Pesce, C.G.;Colman-Lerner, A. (...)Brent, R. Nature. 456(7223):755-761
"Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway" (2008) Pérez-Pérez, A.;Maymó, J.;Dueñas, J.L. (...)Sánchez-Margalet, V. Archives of Biochemistry and Biophysics. 477(2):390-395
"Down-modulation of erbB2 activity is necessary but not enough in the differentiation of 3T3-L1 preadipocytes" (2008) Pagano, E.; Coso, O.; Calvo, J.C. Journal of Cellular Biochemistry. 104(1):274-285
"Down-modulation of erbB2 activity is necessary but not enough in the differentiation of 3T3-L1 preadipocytes" (2008) Pagano, E.; Coso, O.; Calvo, J.C. Journal of Cellular Biochemistry. 104(1):274-285
"Different signaling pathways are involved in cardiomyocyte survival induced by a Trypanosoma cruzi glycoprotein" (2006) Aoki, M.d.P.;Cano, R.C.;Pellegrini, A.V. (...)Gea, S. Microbes and Infection. 8(7):1723-1731
"CRF signaling: molecular specificity for drug targeting in the CNS" (2006) Arzt, E.; Holsboer, F. Trends in Pharmacological Sciences. 27(10):531-538
"Lessons from a crab: Molecular mechanisms in different memory phases of Chasmagnathus" (2006) Romano, A.;Locatelli, F.;Freudenthal, R. (...)Fustiñana, M.S. Biological Bulletin. 210(3):280-288
"Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation" (2006) Dekanty, A.;Sauane, M.;Cadenas, B. (...)Jiménez De Asúa, L. Journal of Biological Chemistry. 281(10):6136-6143
"Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation" (2006) Salatino, M.;Beguelin, W.;Peters, M.G. (...)Elizalde, P.V. Oncogene. 25(59):7723-7739
"Differential involvement of ERK1-2 and p38MAPK activation on Swiss 3T3 cell proliferation induced by prostaglandin F2α" (2006) Dekanty, A.;Giulianelli, S.;Coso, O.A. (...)Jimenez de Asua, L. FEBS Letters. 580(10):2512-2516
"Cell growth-dependent subcellular localization of p8" (2006) Valacco, M.P.;Varone, C.;Malicet, C. (...)Moreno, S. Journal of Cellular Biochemistry. 97(5):1066-1079
"Cross-talk between signaling pathways regulates alternative splicing: A novel role for JNK" (2005) Pelisch, F.; Blaustein, M.; Kornblihtt, A.R.; Srebrow, A. Journal of Biological Chemistry. 280(27):25461-25469
"Signaling processes in tumoral neuroendocrine pituitary cells as potential targets for therapeutic drugs" (2005) Paez-Pereda, M.;Giacomini, D.;Echenique, C. (...)Arzt, E. Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5(3):259-267
"Differential modulation of MAP kinases by zinc deficiency in IMR-32 cells: Role of H2O2" (2005) Zago, M.P.;Mackenzie, G.G.;Adamo, A.M. (...)Oteiza, P.I. Antioxidants and Redox Signaling. 7(11-12):1773-1782
"Different enzymatic activities recruitment by specific domains of TIF2 are involved in NF-κB transactivation " (2004) Nojek, I.M.;Werbajh, S.E.;Colo, G.P. (...)Costas, M.A. Medicina. 64(2):135-138
"Arginase induction promotes Trypanosoma cruzi intracellular replication of Cruzipain-treated J774 cells through the activation of multiple signaling pathways" (2004) Stempin, C.C.; Tanos, T.B.; Coso, O.A.; Cerbán, F.M. European Journal of Immunology. 34(1):200-209
"Inhibition of serum-stimulated mitogen activated protein kinase by 1α,25(OH)2-vitamin D3 in MCF-7 breast cancer cells" (2004) Capiati, D.A.;Rossi, A.M.;Picotto, G. (...)Boland, R.L. Journal of Cellular Biochemistry. 93(2):384-397
"Inhibition of serum-stimulated mitogen activated protein kinase by 1α,25(OH)2-vitamin D3 in MCF-7 breast cancer cells" (2004) Capiati, D.A.;Rossi, A.M.;Picotto, G. (...)Boland, R.L. Journal of Cellular Biochemistry. 93(2):384-397
"Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer " (2004) Salatino, M.;Schillaci, R.;Proietti, C.J. (...)Elizalde, P.V. Medicina. 64(2):129-134
"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746
"Gonadotropin-releasing hormone signaling pathways in an experimental ovarian tumor" (2003) Chamson-Reig, A.;Sorianello, E.M.;Catalano, P.N. (...)Lux-Lantos, V.A.R. Endocrinology. 144(7):2957-2966
"Angiotensin II phosphorylation of extracellular signal-regulated kinases in rat anterior pituitary cells" (2003) Suárez, C.;Díaz-Torga, G.;Gonzalez-Iglesias, A. (...)Becu-Villalobos, D. American Journal of Physiology - Endocrinology and Metabolism. 285(3 48-3):E645-E653
"Activation and induction of Nur77/Nurr1 in corticotrophs by CRH/cAMP: Involvement of calcium, protein kinase a, and MAPK pathways" (2002) Kovalovsky, D.;Refojo, D.;Liberman, A.C. (...)Arzt, E. Molecular Endocrinology. 16(7):1638-1651
"gp130 cytokine signaling in the pituitary gland: A paradigm for cytokine-neuro-endocrine pathways" (2001) Arzt, E. Journal of Clinical Investigation. 108(12):1729-1733