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Mice, Transgenic

"The effects of single-dose injections of modafinil and methamphetamine on epigenetic and functional markers in the mouse medial prefrontal cortex: potential role of dopamine receptors" (2019) González, B.;Torres, O.V.;Jayanthi, S. (...)Bisagno, V. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 88:222-234

"Chronic expression of wild-type Ret receptor in the mammary gland induces luminal tumors that are sensitive to Ret inhibition" (2018) Gattelli, A.;García Solá, M.E.;Roloff, T.C. (...)Hynes, N.E. Oncogene. 37(29):4046-4054

"Positive regulation of raphe serotonin neurons by serotonin 2B receptors" (2018) Belmer, A.;Quentin, E.;Diaz, S.L. (...)Maroteaux, L. Neuropsychopharmacology. 43(7):1623-1632

"Leptin alters somatosensory thalamic networks by decreasing gaba release from reticular thalamic nucleus and action potential frequency at ventrobasal neurons" (2018) Perissinotti, P.P.;Rivero-Echeto, M.C.;Garcia-Rill, E. (...)Urbano, F.J. Brain Structure and Function. 223(5):2499-2514

"Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk" (2018) Orozco, C.A.;Martinez-Bosch, N.;Guerrero, P.E. (...)Navarro, P. Proceedings of the National Academy of Sciences of the United States of America. 115(16):E3769-E3778

"Inhibition of striatal cholinergic interneuron activity by the Kv7 opener retigabine and the nonsteroidal anti-inflammatory drug diclofenac" (2018) Paz, R.M.;Tubert, C.;Stahl, A. (...)Rela, L. Neuropharmacology. 137:309-321

"Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction" (2017) Bertone, N.I.;Groisman, A.I.;Mazzone, G.L. (...)Uchitel, O.D. Synapse. 71(12)

"Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling" (2016) Lemos, J.C.;Friend, D.M.;Kaplan, A.R. (...)Alvarez, V.A. Neuron. 90(4):824-838

"Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization" (2016) Pomilio, C.;Pavia, P.;Gorojod, R.M. (...)Saravia, F. Hippocampus. 26(2):194-210

"Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of Cocaine" (2016) Dobbs, L.K.;Kaplan, A.R.;Lemos, J.C. (...)Alvarez, V.A. Neuron. 90(5):1100-1113

"The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells" (2016) Chaves-Ferreira, M.;Krenn, G.;Vasseur, F. (...)Laderach, D. Biology Direct. 11(1)

"In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B" (2015) Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. PLoS ONE. 10(2)

"Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice" (2015) Inchauspe, C.G.;Pilati, N.;Di Guilmi, M.N. (...)Uchitel, O.D. Hearing Research. 319:56-68

"Presynaptic D 2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus" (2015) Rocchetti, J.;Isingrini, E.;Dal Bo, G. (...)Giros, B. Biological Psychiatry. 77(6):513-525

"Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood" (2015) Nasif, S.;De Souza, F.S.J.;González, L.E. (...)Rubinstein, M. Proceedings of the National Academy of Sciences of the United States of America. 112(15):E1861-E1870

"Antitumor responses stimulated by dendritic cells are improved by triiodothyronine binding to the thyroid hormone receptor β" (2015) Alamino, V.A.;Mascanfroni, I.D.;Montesinos, M.M. (...)Pellizas, C.G. Cancer Research. 75(7):1265-1274

"Elevated hypothalamic aromatization at the onset of precocious puberty in transgenic female mice hypersecreting human chorionic gonadotropin: Effect of androgens" (2014) Gonzalez, B.;Ratner, L.D.;Scerbo, M.J. (...)Rulli, S.B. Molecular and Cellular Endocrinology. 390(1-2):102-111

"Astroglial mGlu3 receptors promote alpha-secretase-mediated amyloid precursor protein cleavage" (2014) Durand, D.;Carniglia, L.;Beauquis, J. (...)Lasaga, M. Neuropharmacology. 79:180-189

"Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i" (2014) Di Guilmi, M.N.;Wang, T.;Inchauspe, C.G. (...)Uchitel, O.D. Journal of Neuroscience. 34(21):7047-7058

"Mouse models of altered gonadotrophin action: Insight into male reproductive disorders" (2014) Jonas, K.C.;Oduwole, O.O.;Peltoketo, H. (...)Huhtaniemi, I.T. Reproduction. 148(4):R63-R70

"Hippocampal and cognitive alterations precede amyloid deposition in a mouse model of al- zheimer’s disease " (2014) Beauquis, J.;Vinuesa, Á.;Pomilio, C. (...)Saravia, F. Medicina (Argentina). 74(4):282-286

"Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease" (2014) Beauquis, J.;Vinuesa, A.;Pomilio, C. (...)Saravia, F. Hippocampus. 24(3):257-269

"Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes" (2014) Castro, C.N.;Barcala Tabarrozzi, A.E.;Winnewisser, J. (...)Perone, M.J. Clinical and Experimental Immunology. 177(1):149-160

"Central dopamine D2 receptors regulate growth-hormone- dependent body growth and pheromone signaling to conspecific males" (2013) Noaín, D.;Pérez-Millán, M.I.;Bello, E.P. (...)Rubinstein, M. Journal of Neuroscience. 33(13):5834-5842

"Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease" (2013) Beauquis, J.;Pavía, P.;Pomilio, C. (...)Saravia, F. Experimental Neurology. 239(1):28-37

"Presynaptic Cav2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held" (2012) Inchauspe, C.G.;Urbano, F.J.;Di Guilmi, M.N. (...)Uchitel, O.D. Journal of Neurophysiology. 108(11):2967-2976

"Ca V2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis" (2012) Uchitel, O.D.; Inchauspe, C.G.; Urbano, F.J.; Di Guilmi, M.N. Journal of Physiology Paris. 106(1-2):12-22

"Early and adult hippocampal TGF-β1 overexpression have opposite effects on behavior" (2011) Depino, A.M.; Lucchina, L.; Pitossi, F. Brain, Behavior, and Immunity. 25(8):1582-1591

"Active and total transforming growth factor-β1 are differentially regulated by dopamine and estradiol in the pituitary" (2011) Recouvreux, M.V.;Guida, M.C.;Rifkin, D.B. (...)Díaz-Torga, G. Endocrinology. 152(7):2722-2730

"Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes" (2011) Lee, A.K.;Smart, J.L.;Rubinstein, M. (...)Tse, A. Endocrinology. 152(5):1901-1910

"Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons" (2011) Franchini, L.F.;López-Leal, R.;Nasif, S. (...)Rubinstein, M. Proceedings of the National Academy of Sciences of the United States of America. 108(37):15270-15275

"Animal models for aberrations of gonadotropin action" (2011) Peltoketo, H.; Zhang, F.-P.; Rulli, S.B. Reviews in Endocrine and Metabolic Disorders. 12(4):245-258

"P/Q-type calcium channel ablation in a mice glycinergic synapse mediated by multiple types of Ca 2+ channels alters transmitter release and short term plasticity" (2011) Giugovaz-Tropper, B.;González-Inchauspe, C.;Di Guilmi, M.N. (...)Uchitel, O.D. Neuroscience. 192:219-230

"Gain of function in FHM-1 CaV2.1 knock-in mice is related to the shape of the action potential" (2010) Inchauspe, C.G.;Urbano, F.J.;Di Guilmi, M.N. (...)Uchitel, O.D. Journal of Neurophysiology. 104(1):291-299

"Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels" (2010) Ahtiainen, P.;Sharp, V.;Rulli, S.B. (...)Huhtaniemi, I. Endocrine-Related Cancer. 17(3):611-621

"Cuprizone-Induced demyelination in CNP::GFP transgenic mice" (2010) Silvestroff, L.;Bartucci, S.;Soto, E. (...)Franco, P. Journal of Comparative Neurology. 518(12):2261-2283

"Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions" (2009) Silberstein, S.;Vogl, A.M.;Refojo, D. (...)Arzt, E. Neuroscience. 159(2):610-617

"Suppression of autoimmune diabetes by soluble galectin-1" (2009) Perone, M.J.;Bertera, S.;Shufesky, W.J. (...)Morelli, A.E. Journal of Immunology. 182(5):2641-2653

"Constitutive expression of the α10 nicotinic acetylcholine receptor subunit fails to maintain cholinergic responses in inner hair cells after the onset of hearing" (2009) Taranda, J.;Ballestero, J.A.;Hiel, H. (...)Elgoyhen, A.B. JARO - Journal of the Association for Research in Otolaryngology. 10(3):397-406

"Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons" (2008) Guo, C.;Qiu, H.-Y.;Shi, M. (...)Ding, Y.-Q. Journal of Neuroscience. 28(52):14097-14106

"Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence" (2007) Bumaschny, V.F.;De Souza, F.S.J.;Leal, R.A.L. (...)Rubinstein, M. Molecular Endocrinology. 21(11):2738-2749

"Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene" (2007) Santangelo, A.M.;De Souza, F.S.J.;Franchini, L.F. (...)Rubinstein, M. PLoS Genetics. 3(10):1813-1826

"A pivotal role for galectin-1 in fetomaternal tolerance" (2007) Blois, S.M.;Ilarregui, J.M.;Tometten, M. (...)Arck, P.C. Nature Medicine. 13(12):1450-1457

"Genetically modified mouse models in studies of luteinising hormone action" (2006) Huhtaniemi, I.;Ahtiainen, P.;Pakarainen, T. (...)Poutanen, M. Molecular and Cellular Endocrinology. 252(1-2):126-135

"Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice" (2006) Noaín, D.;Avale, M.E.;Wedemeyer, C. (...)Rubinstein, M. European Journal of Neuroscience. 24(9):2429-2438

"What have gonadotrophin overexpressing transgenic mice taught us about gonadal function?" (2005) Rulli, S.B.; Huntaniemi, I. Reproduction. 130(3):283-291

"Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: A study on hCG overexpressing transgenic mice" (2005) Ahtiainen, P.;Rulli, S.B.;Shariatmadari, R. (...)Huhtaniemi, I.T. Oncogene. 24(49):7301-7309

"Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting" (2005) De Souza, F.S.J.;Santangelo, A.M.;Bumaschny, V. (...)Rubinstein, M. Molecular and Cellular Biology. 25(8):3076-3086

"Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas" (2005) Refojo, D.;Echenique, C.;Müller, M.B. (...)Arzt, E. Proceedings of the National Academy of Sciences of the United States of America. 102(17):6183-6188

"A Transgenic Marker for Newly Born Granule Cells in Dentate Gyrus" (2004) Overstreet, L.S.;Hentges, S.T.;Bumaschny, V.F. (...)Rubinstein, M. Journal of Neuroscience. 24(13):3251-3259

"Transgenic mice engineered to target Cre/LoxP-mediated DNA recombination into catecholaminergic neurons" (2003) Gelman, D.M.;Noaín, D.;Avale, M.E. (...)Rubinstein, M. Genesis. 36(4):196-202

"Molecular biology and medicine at the end of the XXth century " (2000) Kornblihtt, A.R. Medicina. 60(1):9-16

"Authentic cell-specific and developmentally regulated expression of pro- opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice" (1998) Young, J.I.;Otero, V.;Cerdán, M.G. (...)Rubinstein, M. Journal of Neuroscience. 18(17):6631-6640

"Accurate spatial and temporal transgene expression driven by a 3.8- kilobase promoter of the bovine β-casein gene in the lactating mouse mammary gland" (1998) Cerdán, M.G.;Young, J.I.;Zino, E. (...)Rubinstein, M. Molecular Reproduction and Development. 49(3):236-245