Registro:

Referencias:

• Akiyama, H., Arai, T., Kondo, H., Tanno, E., Haga, C., Ikeda, K., Cell mediators of inflammation in the Alzheimer disease brain (2000) Alzheimer Dis. Assoc. Disord., 14 (SUPPL. 1), pp. 47-S53
• Bailey, J.A., Ray, B., Greig, N.H., Lahiri, D.K., Rivastigmine lowers Abeta and increases sAPPalpha levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons (2011) PLoS One, 6, p. 21954
• Balazs, R., Miller, S., Romano, C., De Vries, A., Chun, Y., Cotman, C.W., Metabotropic glutamate receptor mGluR5 in astrocytes: Pharmacological properties and agonist regulation (1997) J. Neurochem., 69, pp. 151-163
• Bandyopadhyay, S., Hartley, D.M., Cahill, C.M., Lahiri, D.K., Chattopadhyay, N., Rogers, J.T., Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase (2006) J. Neurosci. Res., 84, pp. 106-118
• Beauquis, J., Pavia, P., Pomilio, C., Vinuesa, A., Podlutskaya, N., Galvan, V., Saravia, F., Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease (2013) Exp. Neurol., 239, pp. 28-37
• Berent-Spillson, A., Robinson, A.M., Golovoy, D., Slusher, B., Rojas, C., Russell, J.W., Protection against glucose-induced neuronal death by NAAG and GCP II inhibition is regulated by mGluR3 (2004) J. Neurochem., 89, pp. 90-99
• Bettegazzi, B., Mihailovich, M., Di Cesare, A., Consonni, A., Macco, R., Pelizzoni, I., Codazzi, F., Zacchetti, D., Beta-Secretase activity in rat astrocytes: Translational block of BACE1 and modulation of BACE2 expression (2011) Eur. J. Neurosci., 33, pp. 236-243
• Bigl, M., Apelt, J., Luschekina, E.A., Lange-Dohna, C., Rossner, S., Schliebs, R., Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology (2000) Neurosci. Lett., 292, pp. 107-110
• Bolte, S., Cordelieres, F.P., A guided tour into subcellular colocalization analysis in light microscopy (2006) J. Microsc., 224, pp. 213-232
• Bond, A., Jones, N.M., Hicks, C.A., Whiffin, G.M., Ward, M.A., O'Neill, M.F., Kingston, A.E., O'Neill, M.J., Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: Investigations into possible mechanism of action in vivo (2000) J. Pharmacol. Exp. Ther., 294, pp. 800-809
• Bour, A., Little, S., Dodart, J.C., Kelche, C., Mathis, C., A secreted form of the beta-amyloid precursor protein (sAPP695) improves spatial recognition memory in OF1 mice (2004) Neurobiol. Learn Mem., 81, pp. 27-38
• Bruno, V., Battaglia, G., Casabona, G., Copani, A., Caciagli, F., Nicoletti, F., Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta (1998) J. Neurosci., 18, pp. 9594-9600
• Buisson, A., Choi, D.W., The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death (1995) Neuropharmacology, 34, pp. 1081-1087
• Camacho, I.E., Serneels, L., Spittaels, K., Merchiers, P., Dominguez, D., De Strooper, B., Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide (2004) J. Neurosci., 24, pp. 10908-10917
• Caraci, F., Molinaro, G., Battaglia, G., Giuffrida, M.L., Riozzi, B., Traficante, A., Bruno, V., Nicoletti, F., Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: Selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (2011) Mol. Pharmacol., 79, pp. 618-626
• Caraci, F., Battaglia, G., Bruno, V., Bosco, P., Carbonaro, V., Giuffrida, M.L., Drago, F., Copani, A., TGF-beta1 pathway as a new target for neuroprotection in Alzheimer's disease (2011) CNS Neurosci. Ther., 17, pp. 237-249
• Ciccarelli, R., Di Iorio, P., Bruno, V., Battaglia, G., D'Alimonte, I., D'Onofrio, M., Nicoletti, F., Caciagli, F., Activation of A(1) adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100beta protein from cultured astrocytes (1999) Glia, 27, pp. 275-281
• Ciccarelli, R., D'Alimonte, I., Ballerini, P., D'Auro, M., Nargi, E., Buccella, S., Di Iorio, P., Caciagli, F., Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes (2007) Mol. Pharmacol., 71, pp. 1369-1380
• Condorelli, D.F., Dell'Albani, P., Corsaro, M., Giuffrida, R., Caruso, A., Trovato Salinaro, A., Spinella, F., Giuffrida Stella, A.M., Metabotropic glutamate receptor expression in cultured rat astrocytes and human gliomas (1997) Neurochem. Res., 22, pp. 1127-1133
• Copani, A., Bruno, V., Battaglia, G., Leanza, G., Pellitteri, R., Russo, A., Stanzani, S., Nicoletti, F., Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide (1995) Mol. Pharmacol., 47, pp. 890-897
• Corrigan, F., Pham, C.L., Vink, R., Blumbergs, P.C., Masters, C.L., Van Den Heuvel, C., Cappai, R., The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains (2011) Brain Res., 1378, pp. 137-143
• Corti, C., Battaglia, G., Molinaro, G., Riozzi, B., Pittaluga, A., Corsi, M., Mugnaini, M., Bruno, V., The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/ neuroprotection (2007) J. Neurosci., 27, pp. 8297-8308
• Cha, J.H., Farrell, L.A., Ahmed, S.F., Frey, A., Hsiao-Ashe, K.K., Young, A.B., Penney, J.B., Irizarry, M.C., Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein (2001) Neurobiol. Dis., 8, pp. 90-102
• Chasseigneaux, S., Allinquant, B., Functions of Abeta, sAPPalpha and sAPPbeta: Similarities and differences (2012) J. Neurochem., 120 (SUPPL. 1), pp. 99-108
• Chong, Z.Z., Li, F., Maiese, K., Employing new cellular therapeutic targets for Alzheimer's disease: A change for the better? (2005) Curr. Neurovasc. Res., 2, pp. 55-72
• D'Onofrio, M., Cuomo, L., Battaglia, G., Ngomba, R.T., Storto, M., Kingston, A.E., Orzi, F., Bruno, V., Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways (2001) J. Neurochem., 78, pp. 435-445
• De Pietri Tonelli, D., Mihailovich, M., Di Cesare, A., Codazzi, F., Grohovaz, F., Zacchetti, D., Translational regulation of BACE-1 expression in neuronal and non-neuronal cells (2004) Nucleic Acids Res., 32, pp. 1808-1817
• De Quervain, D.J., Papassotiropoulos, A., Identification of a genetic cluster influencing memory performance and hippocampal activity in humans (2006) Proc. Natl. Acad. Sci. U. S. A., 103, pp. 4270-4274
• Demars, M.P., Bartholomew, A., Strakova, Z., Lazarov, O., Soluble amyloid precursor protein: A novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin (2011) Stem Cell Res. Ther., 2, p. 36
• Dewar, D., Chalmers, D.T., Graham, D.I., McCulloch, J., Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: An autoradiographic study of the hippocampus (1991) Brain Res., 553, pp. 58-64
• Durand, D., Caruso, C., Carniglia, L., Lasaga, M., Metabotropic glutamate receptor 3 activation prevents nitric oxide-induced death in cultured rat astrocytes (2010) J. Neurochem., 112, pp. 420-433
• Durand, D., Carniglia, L., Caruso, C., Lasaga, M., Reduced cAMP, Akt activation and p65-c-Rel dimerization: Mechanisms involved in the protective effects of mGluR3 agonists in cultured astrocytes (2011) PLoS One, 6, p. 22235
• Durand, D., Carniglia, L., Caruso, C., Lasaga, M., MGlu3 receptor and astrocytes: Partners in neuroprotection (2013) Neuropharmacology, 66, pp. 1-11
• Efthimiopoulos, S., Punj, S., Manolopoulos, V., Pangalos, M., Wang, G.P., Refolo, L.M., Robakis, N.K., Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein (1996) J. Neurochem., 67, pp. 872-875
• Egan, M.F., Straub, R.E., Goldberg, T.E., Yakub, I., Callicott, J.H., Hariri, A.R., Mattay, V.S., Weinberger, D.R., Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia (2004) Proc. Natl. Acad. Sci. U. S. A., 101, pp. 12604-12609
• Ferraguti, F., Corti, C., Valerio, E., Mion, S., Xuereb, J., Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5 (2001) Exp. Brain Res., 137, pp. 1-11
• Fu, M., Zhang, J., Lin, Y., Zhu, X., Zhao, L., Ahmad, M., Ehrengruber, M.U., Chen, Y.E., Early stimulation and late inhibition of peroxisome proliferator- activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: Role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads (2003) Biochem. J., 370, pp. 1019-1025
• Funato, H., Yoshimura, M., Yamazaki, T., Saido, T.C., Ito, Y., Yokofujita, J., Okeda, R., Ihara, Y., Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain (1998) Am. J. Pathol., 152, pp. 983-992
• Gakhar-Koppole, N., Hundeshagen, P., Mandl, C., Weyer, S.W., Allinquant, B., Muller, U., Ciccolini, F., Activity requires soluble amyloid precursor protein alpha to promote neurite outgrowth in neural stem cell-derived neurons via activation of the MAPK pathway (2008) Eur. J. Neurosci., 28, pp. 871-882
• Galvan, V., Gorostiza, O.F., Banwait, S., Ataie, M., Logvinova, A.V., Sitaraman, S., Carlson, E., Bredesen, D.E., Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664 (2006) Proc. Natl. Acad. Sci. U. S. A., 103, pp. 7130-7135
• Gatta, L.B., Albertini, A., Ravid, R., Finazzi, D., Levels of beta-secretase BACE and alpha-secretase ADAM10 mRNAs in Alzheimer hippocampus (2002) Neuroreport, 13, pp. 2031-2033
• Hartlage-Rubsamen, M., Zeitschel, U., Apelt, J., Gartner, U., Franke, H., Stahl, T., Gunther, A., Rossner, S., Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent (2003) Glia, 41, pp. 169-179
• Hauser, S., Adelmant, G., Sarraf, P., Wright, H.M., Mueller, E., Spiegelman, B.M., Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation (2000) J. Biol. Chem., 275, pp. 18527-18533
• Heneka, M.T., Sastre, M., Dumitrescu-Ozimek, L., Hanke, A., Dewachter, I., Kuiperi, C., O'Banion, K., Landreth, G.E., Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice (2005) Brain, 128, pp. 1442-1453
• Hsia, A.Y., Masliah, E., McConlogue, L., Yu, G.Q., Tatsuno, G., Hu, K., Kholodenko, D., Mucke, L., Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models (1999) Proc. Natl. Acad. Sci. U. S. A., 96, pp. 3228-3233
• Jin, L.W., Ninomiya, H., Roch, J.M., Schubert, D., Masliah, E., Otero, D.A., Saitoh, T., Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension (1994) J. Neurosci., 14, pp. 5461-5470
• Jorissen, E., Prox, J., Bernreuther, C., Weber, S., Schwanbeck, R., Serneels, L., Snellinx, A., Saftig, P., The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex (2010) J. Neurosci., 30, pp. 4833-4844
• Kieseier, B.C., Pischel, H., Neuen-Jacob, E., Tourtellotte, W.W., Hartung, H.P., ADAM-10 and ADAM-17 in the inflamed human CNS (2003) Glia, 42, pp. 398-405
• Kim, S.H., Fraser, P.E., Westaway, D., St George-Hyslop, P.H., Ehrlich, M.E., Gandy, S., Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals (2010) J. Neurosci., 30, pp. 3870-3875
• Kingston, A.E., O'Neill, M.J., Bond, A., Bruno, V., Battaglia, G., Nicoletti, F., Harris, J.R., Schoepp, D.D., Neuroprotective actions of novel and potent ligands of group i and group II metabotropic glutamate receptors (1999) Ann. N. Y. Acad. Sci., 890, pp. 438-449
• Lane, R.F., Shineman, D.W., Steele, J.W., Lee, L.B., Fillit, H.M., Beyond amyloid: The future of therapeutics for Alzheimer's disease (2012) Adv. Pharmacol., 64, pp. 213-271
• Leal, M.C., Dorfman, V.B., Gamba, A.F., Frangione, B., Wisniewski, T., Castano, E.M., Sigurdsson, E.M., Morelli, L., Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology (2006) J. Neuropathol. Exp. Neurol., 65, pp. 976-987
• Lee, H.G., Ogawa, O., Zhu, X., O'Neill, M.J., Petersen, R.B., Castellani, R.J., Ghanbari, H., Smith, M.A., Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease (2004) Acta Neuropathol., 107, pp. 365-371
• Lee, R.K., Wurtman, R.J., Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP (1997) J. Neurochem., 68, pp. 1830-1835
• Li, Y.C., Chen, Q., Wan, X.Z., Yang, X.L., Liu, X., Zhong, L., Effects of conjugated linoleic acid on cleavage of amyloid precursor protein via PPARgamma (2011) Neurol. Sci., 32, pp. 1095-1101
• Livak, K.J., Schmittgen, T.D., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method (2001) Methods, 25, pp. 402-408
• Luedecking, E.K., Dekosky, S.T., Mehdi, H., Ganguli, M., Kamboh, M.I., Analysis of genetic polymorphisms in the transforming growth factor-beta1 gene and the risk of Alzheimer's disease (2000) Hum. Genet., 106, pp. 565-569
• Luth, H.J., Holzer, M., Gartner, U., Staufenbiel, M., Arendt, T., Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease, in APP23 transgenic mice and after experimental brain lesion in rat: Evidence for an induction by amyloid pathology (2001) Brain Res., 913, pp. 57-67
• Manders, E.M., Stap, J., Brakenhoff, G.J., Van Driel, R., Aten, J.A., Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy (1992) J. Cell Sci., 103 (PART 3), pp. 857-862
• Mandrekar-Colucci, S., Karlo, J.C., Landreth, G.E., Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease (2012) J. Neurosci., 32, pp. 10117-10128
• Marcinkiewicz, M., Seidah, N.G., Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain (2000) J. Neurochem., 75, pp. 2133-2143
• Martinez, M., Fernandez, E., Frank, A., Guaza, C., De La Fuente, M., Hernanz, A., Increased cerebrospinal fluid cAMP levels in Alzheimer's disease (1999) Brain Res., 846, pp. 265-267
• Matarredona, E.R., Santiago, M., Venero, J.L., Cano, J., Machado, A., Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction (2001) J. Neurochem., 76, pp. 351-360
• Mattson, M.P., Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives (1997) Physiol. Rev., 77, pp. 1081-1132
• Meziane, H., Dodart, J.C., Mathis, C., Little, S., Clemens, J., Paul, S.M., Ungerer, A., Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice (1998) Proc. Natl. Acad. Sci. U. S. A., 95, pp. 12683-12688
• Mihailovich, M., Thermann, R., Grohovaz, F., Hentze, M.W., Zacchetti, D., Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region (2007) Nucleic Acids Res., 35, pp. 2975-2985
• Miyamoto, M., Ishida, M., Shinozaki, H., Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat (1997) Neuroscience, 77, pp. 131-140
• Mucke, L., Masliah, E., Yu, G.Q., Mallory, M., Rockenstein, E.M., Tatsuno, G., Hu, K., McConlogue, L., High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation (2000) J. Neurosci., 20, pp. 4050-4058
• Mudo, G., Trovato-Salinaro, A., Caniglia, G., Cheng, Q., Condorelli, D.F., Cellular localization of mGluR3 and mGluR5 mRNAs in normal and injured rat brain (2007) Brain Res., 1149, pp. 1-13
• Obregon, D., Hou, H., Deng, J., Giunta, B., Tian, J., Darlington, D., Shahaduzzaman, M., Tan, J., Soluble amyloid precursor protein-alpha modulates beta-secretase activity and amyloid-beta generation (2012) Nat. Commun., 3, p. 777
• Oddo, S., Caccamo, A., Shepherd, J.D., Murphy, M.P., Golde, T.E., Kayed, R., Metherate, R., Laferla, F.M., Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction (2003) Neuron, 39, pp. 409-421
• Ohishi, H., Shigemoto, R., Nakanishi, S., Mizuno, N., Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat (1993) Neuroscience, 53, pp. 1009-1018
• Ohishi, H., Shigemoto, R., Nakanishi, S., Mizuno, N., Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study (1993) J. Comp. Neurol., 335, pp. 252-266
• Ohishi, H., Neki, A., Mizuno, N., Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: An immunohistochemical study with a monoclonal antibody (1998) Neurosci. Res., 30, pp. 65-82
• Ohsawa, I., Takamura, C., Kohsaka, S., The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture (1997) Biochem. Biophys. Res. Commun., 236, pp. 59-65
• Ohsawa, I., Takamura, C., Morimoto, T., Ishiguro, M., Kohsaka, S., Amino-terminal region of secreted form of amyloid precursor protein stimulates proliferation of neural stem cells (1999) Eur. J. Neurosci., 11, pp. 1907-1913
• Pacheco Otalora, L.F., Couoh, J., Shigamoto, R., Zarei, M.M., Garrido Sanabria, E.R., Abnormal mGluR2/3 expression in the perforant path termination zones and mossy fibers of chronically epileptic rats (2006) Brain Res., 1098, pp. 170-185
• Patterson, C., Feightner, J.W., Garcia, A., Hsiung, G.Y., Macknight, C., Sadovnick, A.D., Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease (2008) CMAJ, 178, pp. 548-556
• Petralia, R.S., Wang, Y.X., Niedzielski, A.S., Wenthold, R.J., The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations (1996) Neuroscience, 71, pp. 949-976
• Pietrzik, C.U., Hoffmann, J., Stober, K., Chen, C.Y., Bauer, C., Otero, D.A., Roch, J.M., Herzog, V., From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells (1998) Proc. Natl. Acad. Sci. U. S. A., 95, pp. 1770-1775
• Postina, R., Schroeder, A., Dewachter, I., Bohl, J., Schmitt, U., Kojro, E., Prinzen, C., Fahrenholz, F., A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model (2004) J. Clin. Invest., 113, pp. 1456-1464
• Preece, P., Virley, D.J., Costandi, M., Coombes, R., Moss, S.J., Mudge, A.W., Jazin, E., Cairns, N.J., Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease (2003) Brain Res. Mol. Brain Res., 116, pp. 155-158
• Qiu, W.Q., Ferreira, A., Miller, C., Koo, E.H., Selkoe, D.J., Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner (1995) J. Neurosci., 15, pp. 2157-2167
• Richards, G., Messer, J., Faull, R.L., Stadler, H., Wichmann, J., Huguenin, P., Bohrmann, B., Mutel, V., Altered distribution of mGlu2 receptors in beta-amyloid-affected brain regions of Alzheimer cases and aged PS2APP mice (2010) Brain Res., 1363, pp. 180-190
• Robinson, R.A., Lange, M.B., Sultana, R., Galvan, V., Fombonne, J., Gorostiza, O., Zhang, J., Butterfield, D.A., Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: Effects of the amyloid-beta peptide of amyloid precursor protein (2011) Neuroscience, 177, pp. 207-222
• Rodriguez, J.J., Olabarria, M., Chvatal, A., Verkhratsky, A., Astroglia in dementia and Alzheimer's disease (2009) Cell Death Differ., 16, pp. 378-385
• Rossner, S., Apelt, J., Schliebs, R., Perez-Polo, J.R., Bigl, V., Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology (2001) J. Neurosci. Res., 64, pp. 437-446
• Saitoh, T., Sundsmo, M., Roch, J.M., Kimura, N., Cole, G., Schubert, D., Oltersdorf, T., Schenk, D.B., Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts (1989) Cell, 58, pp. 615-622
• Sastre, M., Dewachter, I., Landreth, G.E., Willson, T.M., Klockgether, T., Van Leuven, F., Heneka, M.T., Nonsteroidal anti-inflammatory drugs and peroxisome proliferator- activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase (2003) J. Neurosci., 23, pp. 9796-9804
• Sastre, M., Dewachter, I., Rossner, S., Bogdanovic, N., Rosen, E., Borghgraef, P., Evert, B.O., Heneka, M.T., Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma (2006) Proc. Natl. Acad. Sci. U. S. A., 103, pp. 443-448
• Sastre, M., Walter, J., Gentleman, S.M., Interactions between APP secretases and inflammatory mediators (2008) J. Neuroinflam., 5, p. 25
• Schobel, S., Neumann, S., Seed, B., Lichtenthaler, S.F., Expression cloning screen for modifiers of amyloid precursor protein shedding (2006) Int. J. Dev. Neurosci., 24, pp. 141-148
• Schools, G.P., Kimelberg, H.K., MGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats (1999) J. Neurosci. Res., 58, pp. 533-543
• Shaffer, L.M., Dority, M.D., Gupta-Bansal, R., Frederickson, R.C., Younkin, S.G., Brunden, K.R., Amyloid beta protein (A beta) removal by neuroglial cells in culture (1995) Neurobiol. Aging, 16, pp. 737-745
• Shibata, N., Kobayashi, M., The role for oxidative stress in neurodegenerative diseases (2008) Brain Nerve, 60, pp. 157-170
• Shigemoto, R., Kinoshita, A., Wada, E., Nomura, S., Ohishi, H., Takada, M., Flor, P.J., Mizuno, N., Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus (1997) J. Neurosci., 17, pp. 7503-7522
• Stein, T.D., Johnson, J.A., Genetic programming by the proteolytic fragments of the amyloid precursor protein: Somewhere between confusion and clarity (2003) Rev. Neurosci., 14, pp. 317-341
• Tamaru, Y., Nomura, S., Mizuno, N., Shigemoto, R., Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: Differential location relative to pre- and postsynaptic sites (2001) Neuroscience, 106, pp. 481-503
• Taylor, D.L., Diemel, L.T., Cuzner, M.L., Pocock, J.M., Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease (2002) J. Neurochem., 82, pp. 1179-1191
• Tesseur, I., Zou, K., Esposito, L., Bard, F., Berber, E., Can, J.V., Lin, A.H., Wyss-Coray, T., Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology (2006) J. Clin. Invest., 116, pp. 3060-3069
• Thal, D.R., Hartig, W., Schober, R., Diffuse plaques in the molecular layer show intracellular A beta(8-17)-immunoreactive deposits in subpial astrocytes (1999) Clin. Neuropathol., 18, pp. 226-231
• Thinakaran, G., Koo, E.H., Amyloid precursor protein trafficking, processing, and function (2008) J. Biol. Chem., 283, pp. 29615-29619
• Tousseyn, T., Thathiah, A., Jorissen, E., Raemaekers, T., Konietzko, U., Reiss, K., Maes, E., De Strooper, B., ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase (2009) J. Biol. Chem., 284, pp. 11738-11747
• Turner, P.R., O'Connor, K., Tate, W.P., Abraham, W.C., Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory (2003) Prog. Neurobiol., 70, pp. 1-32
• Waite, K.J., Floyd, Z.E., Arbour-Reily, P., Stephens, J.M., Interferon-gamma-induced regulation of peroxisome proliferator-activated receptor gamma and STATs in adipocytes (2001) J. Biol. Chem., 276, pp. 7062-7068
• Weskamp, G., Cai, H., Brodie, T.A., Higashyama, S., Manova, K., Ludwig, T., Blobel, C.P., Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life (2002) Mol. Cell Biol., 22, pp. 1537-1544
• Wilson, J.X., Antioxidant defense of the brain: A role for astrocytes (1997) Can. J. Physiol. Pharmacol., 75, pp. 1149-1163
• Wright, A.L., Zinn, R., Hohensinn, B., Konen, L.M., Beynon, S.B., Tan, R.P., Clark, I.A., Vissel, B., Neuroinflammation and neuronal loss precede Abeta plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease (2013) PLoS One, 8, p. 59586
• Wyss-Coray, T., Masliah, E., Mallory, M., McConlogue, L., Johnson-Wood, K., Lin, C., Mucke, L., Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease (1997) Nature, 389, pp. 603-606
• Wyss-Coray, T., Loike, J.D., Brionne, T.C., Lu, E., Anankov, R., Yan, F., Silverstein, S.C., Husemann, J., Adult mouse astrocytes degrade amyloid-beta in vitro and in situ (2003) Nat. Med., 9, pp. 453-457
• Yao, H.H., Ding, J.H., Zhou, F., Wang, F., Hu, L.F., Sun, T., Hu, G., Enhancement of glutamate uptake mediates the neuroprotection exerted by activating group II or III metabotropic glutamate receptors on astrocytes (2005) J. Neurochem., 92, pp. 948-961
• Zhao, Y., Calon, F., Julien, C., Winkler, J.W., Petasis, N.A., Lukiw, W.J., Bazan, N.G., Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARgamma-mediated mechanisms in Alzheimer's disease models (2011) PLoS One, 6, p. 15816
• Zhong, C., Zhao, X., Sarva, J., Kozikowski, A., Neale, J.H., Lyeth, B.G., NAAG peptidase inhibitor reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion TBI in rats (2005) J. Neurotrauma, 22, pp. 266-276
• Zhou, F., Yao, H.H., Wu, J.Y., Yang, Y.J., Ding, J.H., Zhang, J., Hu, G., Activation of Group II/III metabotropic glutamate receptors attenuates LPS-induced astroglial neurotoxicity via promoting glutamate uptake (2006) J. Neurosci. Res., 84, pp. 268-277

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------