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IC 50
65
"The system of fucoidans from the brown seaweed Dictyota dichotoma: Chemical analysis and antiviral activity"
(2014) Rabanal, M.;Ponce, N.M.A.;Navarro, D.A. (
...
)Stortz, C.A. Carbohydrate Polymers. 101(1):804-811
"Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line"
(2014) Lang, K.L.;Silva, I.T.;Machado, V.R. (
...
)De Melo, E.B. Journal of Molecular Graphics and Modelling. 48:70-79
"Resistance in cholinesterase activity after an acute and subchronic exposure to azinphos-methyl in the freshwater gastropod Biomphalaria straminea"
(2014) Bianco, K.;Otero, S.;Balazote Oliver, A. (
...
)Kristoff, G. Ecotoxicology and Environmental Safety. 109:85-92
"Enhancing antibacterial activity against Escherichia coli K-12 of peptide Ib-AMP4 with synthetic analogues"
(2014) Flórez-Castillo, J.M.; Perullini, M.; Jobbágy, M.; De Jesús Cano Calle, H. International Journal of Peptide Research and Therapeutics. 20(3):365-369
"Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines"
(2014) Cardama, G.A.;Comin, M.J.;Hornos, L. (
...
)Menna, P.L. Anti-Cancer Agents in Medicinal Chemistry. 14(6):840-851
"Synthesis and cholinesterase inhibition of cativic acid derivatives"
(2014) Alza, N.P.;Richmond, V.;Baier, C.J. (
...
)Murray, A.P. Bioorganic and Medicinal Chemistry. 22(15):3838-3849
"Preparation, anticholinesterase activity and molecular docking of new lupane derivatives"
(2014) Castro, M.J.;Richmond, V.;Romero, C. (
...
)Murray, A.P. Bioorganic and Medicinal Chemistry. 22(13):3341-3350
"Antitumor activity of histamine and clozapine in a mouse experimental model of human melanoma"
(2013) Massari, N.A.;Medina, V.A.;Cricco, G.P. (
...
)Rivera, E.S. Journal of Dermatological Science. 72(3):252-262
"Cholinesterases and neurotoxicity as highly sensitive biomarkers for an organophosphate insecticide in a freshwater gastropod (Chilina gibbosa) with low sensitivity carboxylesterases"
(2013) Bianco, K.;Yusseppone, M.S.;Otero, S. (
...
)Kristoff, G. Aquatic Toxicology. 144-145:26-35
"Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2"
(2013) Guillon, J.;Le Borgne, M.;Rimbault, C. (
...
)Jose, J. European Journal of Medicinal Chemistry. 65:205-222
"Preparation and antitrypanosomal activity of secochiliolide acid derivatives"
(2013) Siless, G.E.;Lozano, E.;Sánchez, M. (
...
)Palermo, J.A. Bioorganic and Medicinal Chemistry Letters. 23(17):4964-4967
"Synthesis and acetylcholinesterase inhibitory activity of polyhydroxylated sulfated steroids: Structure/activity studies"
(2013) Richmond, V.; Murray, A.P.; Maier, M.S. Steroids. 78(11):1141-1147
"Antiparasitic hybrids of Cinchona alkaloids and bile acids"
(2013) Leverrier, A.;Bero, J.;Frédérich, M. (
...
)Palermo, J. European Journal of Medicinal Chemistry. 66:355-363
"Trypanocidal activity of thioamide-substituted imidazoquinolinone: Electrochemical properties and biological effects"
(2013) Frank, F.M.;Ciccarelli, A.B.;Bollini, M. (
...
)Lombardo, M.E. Evidence-based Complementary and Alternative Medicine. 2013
"Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity"
(2012) Oliveira, S.Q.D.;Almeida, M.T.R.D.;Maraslis, F. (
...
)Schenkel, E.P. Phytochemistry Letters. 5(3):500-505
"Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of trypanosoma cruzi farnesyl diphosphate synthase"
(2012) Aripirala, S.;Szajnman, S.H.;Jakoncic, J. (
...
)Amzel, L.M. Journal of Medicinal Chemistry. 55(14):6445-6454
"Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1 A903V and CESA3 T942I of cellulose synthase"
(2012) Harris, D.M.;Corbin, K.;Wang, T. (
...
)DeBolt, S. Proceedings of the National Academy of Sciences of the United States of America. 109(11):4098-4103
"Binary mixtures of azinphos-methyl oxon and chlorpyrifos oxon produce in vitro synergistic cholinesterase inhibition in Planorbarius corneus"
(2012) Cacciatore, L.C.; Kristoff, G.; Verrengia Guerrero, N.R.; Cochón, A.C. Chemosphere. 88(4):450-458
"Antiparasitic effect of vitamin B12 on Trypanosoma cruzi"
(2012) Ciccarelli, A.B.;Frank, F.M.;Puente, V. (
...
)Lombardo, M.E. Antimicrobial Agents and Chemotherapy. 56(10):5315-5320
"Antiviral activity against dengue virus of diverse classes of algal sulfated polysaccharides"
(2012) Pujol, C.A.; Ray, S.; Ray, B.; Damonte, E.B. International Journal of Biological Macromolecules. 51(4):412-416
"Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives"
(2012) Lang, K.L.;Silva, I.T.;Zimmermann, L.A. (
...
)Durán, F.J. Bioorganic and Medicinal Chemistry. 20(9):3016-3030
"2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase"
(2012) Rodrígues-Poveda, C.A.; González-Pacanowska, D.; Szajnman, S.H.; Rodríguez, J.B. Antimicrobial Agents and Chemotherapy. 56(8):4483-4486
"An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic fever arenaviruses"
(2012) Helguera, G.;Jemielity, S.;Abraham, J. (
...
)Choe, H. Journal of Virology. 86(7):4024-4028
"Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan"
(2011) Mateu, C.G.;Recalde, M.P.;Artuso, M.C. (
...
)Carlucci, M.J. Sexually Transmitted Diseases. 38(6):555-561
"Synthesis and acetylcholinesterase inhibitory activity of 2β,3α-disulfoxy-5α-cholestan-6-one"
(2011) Richmond, V.; Santos, G.A.G.; Murray, A.P.; Maier, M.S. Steroids. 76(10-11):1160-1165
"Antimalarial activity of new acridinone derivatives"
(2011) Fernández-Calienes, A.;Pellón, R.;Docampo, M. (
...
)Rojas, L. Biomedicine and Pharmacotherapy. 65(3):210-214
"Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1- bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase"
(2011) Rosso, V.S.;Szajnman, S.H.;Malayil, L. (
...
)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 19(7):2211-2217
"Synthesis and biological evaluation of N-thia-carba-thymidine as an antiherpetic agent"
(2010) Elhalem, E.; Pujol, C.A.; Damonte, E.B.; Rodriguez, J.B. Tetrahedron. 66(18):3332-3340
"Inhibition of cholinesterases and carboxylesterases of two invertebrate species, Biomphalaria glabrata and Lumbriculus variegatus, by the carbamate pesticide carbaryl"
(2010) Kristoff, G.; Guerrero, N.R.V.; Cochón, A.C. Aquatic Toxicology. 96(2):115-123
"Virucidal activity and chemical composition of essential oils from aromatic plants of central west Argentina"
(2010) García, C.C.;Acosta, E.G.;Carro, A.C. (
...
)Damonte, E.B. Natural Product Communications. 5(8):1307-1310
"Inhibitory effect of quercetin on matrix metalloproteinase 9 activity Molecular mechanism and structure-activity relationship of the flavonoid-enzyme interaction"
(2010) Saragusti, A.C.;Ortega, M.G.;Cabrera, J.L. (
...
)Chiabrando, G.A. European Journal of Pharmacology. 644(1-3):138-145
"Inhibition of arenavirus infection by thiuram and aromatic disulfides"
(2010) Sepúlveda, C.S.; García, C.C.; Damonte, E.B. Antiviral Research. 87(3):329-337
"Structural determinants of the multifunctional profile of dual binding site acetylcholinesterase inhibitors as anti-alzheimer agents"
(2010) Galdeano, C.;Viayna, E.;Arroyo, P. (
...
)Luque, F.J. Current Pharmaceutical Design. 16(25):2818-2836
"Dolabellane diterpenoids from the south atlantic gorgonian convexella magelhaenica"
(2010) Rojo De Almeida, M.T.;Siless, G.E.;Perez, C.D. (
...
)Palermo, J.A. Journal of Natural Products. 73(10):1714-1717
"Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells"
(2009) Liberman, A.C.;Druker, J.;Refojo, D. (
...
)Arzt, E. FASEB Journal. 23(5):1558-1571
"Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog"
(2009) Careaga, V.P.;Bueno, C.;Muniain, C. (
...
)Maier, M.S. Chemotherapy. 55(1):60-68
"Sulfated xylomannans from the red seaweed Sebdenia polydactyla: Structural features, chemical modification and antiviral activity"
(2009) Ghosh, T.;Pujol, C.A.;Damonte, E.B. (
...
)Ray, B. Antiviral Chemistry and Chemotherapy. 19(6):235-242
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase"
(2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (
...
)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Polysaccharides from Gracilaria corticata: Sulfation, chemical characterization and anti-HSV activities"
(2008) Chattopadhyay, K.;Ghosh, T.;Pujol, C.A. (
...
)Ray, B. International Journal of Biological Macromolecules. 43(4):346-351
"Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose"
(2007) Agustí, R.;Giorgi, M.E.;Mendoza, V.M. (
...
)de Lederkremer, R.M. Bioorganic and Medicinal Chemistry. 15(7):2611-2616
"Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation"
(2007) Liñares, G.G.;Gismondi, S.;Codesido, N.O. (
...
)Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 17(18):5068-5071
"Current status and progress made in malaria chemotherapy"
(2007) Liñares, G.E.G.; Rodriguez, J.B. Current Medicinal Chemistry. 14(3):289-314
"Effect of chromium on the fatty acid composition of two strains of Euglena gracilis"
(2006) Rocchetta, I.;Mazzuca, M.;Conforti, V. (
...
)De Molina, M.D.C.R. Environmental Pollution. 141(2):353-358
"TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi"
(2006) Alonso, G.D.; Schoijet, A.C.; Torres, H.N.; Flawiá, M.M. Molecular and Biochemical Parasitology. 145(1):40-49
"Effects of quinine, quinidine, and chloroquine on α9α10 nicotinic cholinergic receptors"
(2005) Ballestero, J.A.;Plazas, P.V.;Kracun, S. (
...
)Elgoyhen, A.B. Molecular Pharmacology. 68(3):822-829
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase"
(2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690
"A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between Rat α9α10 and α7 nicotinic cholinergic receptors"
(2005) McIntosh, J.M.;Plazas, P.V.;Watkins, M. (
...
)Elgoyhen, A.B. Journal of Biological Chemistry. 280(34):30107-30112
"Biophysical and pharmacological characterization of nicotinic cholinergic receptors in rat cochlear inner hair cells"
(2005) Gómez-Casati, M.E.; Fuchs, P.A.; Elgoyhen, A.B.; Katz, E. Journal of Physiology. 566(1):103-118
"The antiviral activity of sulfated polysaccharides against dengue virus is dependent on virus serotype and host cell"
(2005) Talarico, L.B.;Pujol, C.A.;Zibetti, R.G.M. (
...
)Damonte, E.B. Antiviral Research. 66(2-3):103-110
"Anti-herpes simplex virus activity of sulfated galactans from the red seaweeds Gymnogongrus griffithsiae and Cryptonemia crenulata"
(2004) Talarico, L.B.;Zibetti, R.G.M.;Faria, P.C.S. (
...
)Damonte, E.B. International Journal of Biological Macromolecules. 34(1-2):63-71
"Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA ρ1 receptor"
(2004) Goutman, J.D.; Calvo, D.J. British Journal of Pharmacology. 141(4):717-727
"Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase"
(2003) Szajnman, S.H.;Montalvetti, A.;Wang, Y. (
...
)Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 13(19):3231-3235
"Differential inhibitory action of two azoic compounds against arenaviruses"
(2003) García, C.C.; Candurra, N.A.; Damonte, E.B. International Journal of Antimicrobial Agents. 21(4):319-324
"ent-Kaur-16-en-19-oic acid, a KB cells cytotoxic diterpenoid from Elaeoselinum foetidum"
(2002) Mongelli, E.;Pomilio, A.B.;Bustamante Sánchez, J. (
...
)Martínez Massanet, G. Phytotherapy Research. 16(4):387-388
"The α9α10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations"
(2002) Weisstaub, N.; Vetter, D.E.; Belén Elgoyhen, A.; Katz, E. Hearing Research. 167(1-2):122-135
"Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum"
(2002) De Macedo, C.S.; Uhrig, M.L.; Kimura, E.A.; Katzin, A.M. FEMS Microbiology Letters. 207(1):13-20
"Mode of inactivation of arenaviruses by disulfide-based compounds"
(2002) García, C.C; Candurra, N.A; Damonte, E.B Antiviral Research. 55(3):437-446
"Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group"
(2002) Amssoms, K.;Oza, S.L.;Ravaschino, E. (
...
)Haemers, A. Bioorganic and Medicinal Chemistry Letters. 12(18):2553-2556
"Evaluation of the antiviral activity against junin virus of macrocyclic trichothecenes produced by the hypocrealean epibiont of Baccharis coridifolia"
(2002) García, C.C.;Rosso, M.L.;Bertoni, M.D. (
...
)Damonte, E.B. Planta Medica. 68(3):209-212
"Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi"
(2002) Elhalem, E.;Bailey, B.N.;Docampo, R. (
...
)Rodriguez, J.B. Journal of Medicinal Chemistry. 45(18):3984-3999
"Binding of nicotinic ligands to and nicotine-induced calcium signaling in Trypanosoma cruzi"
(2001) Bollo, M.; Venera, G.; de Jiménez Bonino, M.B.; Machado-Domenech, E. Biochemical and Biophysical Research Communications. 281(2):300-304
"Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi"
(2001) Szajnman, S.H.; Bailey, B.N.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 11(6):789-792
"Rapid antibiotic susceptibility testing via electrochemical measurement of ferricyanide reduction by Escherichia coli and Clostridium sporogenes"
(2000) Ertl, P.; Robello, E.; Battaglini, F.; Mikkelsen, S.R. Analytical Chemistry. 72(20):4957-4964
"In vitro and in vivo activity of eugenol on human herpesvirus"
(2000) Benencia, F.; Courrges, M.C. Phytotherapy Research. 14(7):495-500
"Antiviral properties of fucoidan fractions from Leathesia difformis."
(1999) Feldman, S.C.;Reynaldi, S.;Stortz, C.A. (
...
)Damont, E.B. Phytomedicine : international journal of phytotherapy and phytopharmacology. 6(5):335-340
Facultad de Ciencias Exactas y Naturales - Universidad de Buenos Aires - Argentina
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