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Referencias:

• Castillo, E., Dea-Ayuela, M.A., Bolás-Fernández, F., Rangel, M., González-Rosende, M.E., The kinetoplastid chemotherapy revisited: Current drugs, recent advances and future perspectives (2010) Current Medicinal Chemistry, 17 (33), pp. 4027-4051. , 2-s2.0-79251504276 10.2174/092986710793205345
• Jannin, J., Villa, L., An overview of Chagas disease treatment (2007) Memorias do Instituto Oswaldo Cruz, 102 (SUPPL. 1), pp. 95-97. , http://memorias.ioc.fiocruz.br/cd_8.pdf
• Mitscher, L.A., Wong, W.C., Demeulenaere, T., Sulko, J., Drake, S., Antimicrobial agents from higher plants. New synthesis and bioactivity of tryptanthrin (indolo [2, 1b]quinazolin-6, 12-dione) and its analogs (1981) Heterocycles, 15, pp. 1017-1018
• Miao, S., Shi, X., Zhang, H., Wang, S., Sun, J., Hua, W., Miao, Q., Zhang, C., Proliferation-attenuating and apoptosis-inducing effects of tryptanthrin on human chronic myeloid leukemia K562 cell line in vitro (2011) International Journal of Molecular Sciences, 12 (6), pp. 3831-3845. , 2-s2.0-79959691978 10.3390/ijms12063831
• Bhattacharjee, A.K., Skanchy, D.J., Jennings, B., Hudson, T.H., Brendle, J.J., Werbovetz, K.A., Analysis of stereoelectronic properties, mechanism of action and pharmacophore of synthetic indolo[2,1-b]quinazoline-6,12-dione derivatives in relation to antileishmanial activity using quantum chemical, cyclic voltammetry and 3-D-QSAR CATALYST procedures (2002) Bioorganic and Medicinal Chemistry, 10 (6), pp. 1979-1989. , DOI 10.1016/S0968-0896(02)00013-5, PII S0968089602000135
• Grant, K.M., Dunion, M.H., Yardley, V., Skaltsounis, A.-L., Marko, D., Eisenbrand, G., Croft, S.L., Mottram, J.C., Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: Chemical library screen and antileishmanial activity (2004) Antimicrobial Agents and Chemotherapy, 48 (8), pp. 3033-3042. , DOI 10.1128/AAC.48.8.3033-3042.2004
• Scovill, J., Blank, E., Konnick, M., Nenortas, E., Shapiro, T., Antitrypanosomal activities of tryptanthrins (2002) Antimicrobial Agents and Chemotherapy, 46 (3), pp. 882-883. , DOI 10.1128/AAC.46.3.882-883.2002
• Bhattacharjee, A.K., Hartell, M.G., Nichols, D.A., Hicks, R.P., Stanton, B., Van Hamont, J.E., Milhous, W.K., Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates (2004) European Journal of Medicinal Chemistry, 39 (1), pp. 59-67. , DOI 10.1016/j.ejmech.2003.10.004
• Krivogorsky, B., Grundt, P., Yolken, R., Jones-Brando, L., Inhibition of Leishmania mexicana by indirubin and tryptanthrin analogs (2008) Antimicrobial Agents and Chemotherapy, 52 (12), pp. 4466-4469. , 2-s2.0-57049167732 10.1128/AAC.00903-08
• Bollini, M., Asis, S.E., Bruno, A.M., Synthesis of 2,3-dihydroimidazo[1,2-b]isoquinoline-5(1H)-one and derivatives (2006) Synthesis, (2), pp. 237-242. , DOI 10.1055/s-2005-918505, M03605SS
• Bollini, M., Casal, J.J., Alvarez, D.E., Boiani, L., González, M., Cerecetto, H., Bruno, A.M., New potent imidazoisoquinolinone derivatives as anti- Trypanosoma cruzi agents: Biological evaluation and structure-activity relationships (2009) Bioorganic and Medicinal Chemistry, 17 (4), pp. 1437-1444. , 2-s2.0-60049087260 10.1016/j.bmc.2009.01.011
• Ciccarelli, A., Araujo, L., Batlle, A., Lombardo, E., Effect of haemin on growth, protein content and the antioxidant defence system in Trypanosoma cruzi (2007) Parasitology, 134 (7), pp. 959-965. , DOI 10.1017/S0031182007002399, PII S0031182007002399
• Buckner, F.S., Verlinde, C.L.M.J., La Flamme, A.C., Van Voorhis, W.C., Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing β-galactosidase (1996) Antimicrobial Agents and Chemotherapy, 40 (11), pp. 2592-2597
• Esteva, M., Ruiz, A.M., Stoka, A.M., Trypanosoma cruzi: Methoprene is a potent agent to sterilize blood infected with trypomastigotes (2002) Experimental Parasitology, 100 (4), pp. 248-251. , DOI 10.1016/S0014-4894(02)00022-X, PII S001448940200022X
• Ciccarelli, A.B., Frank, F.M., Puente, V., Malchiodi, E.L., Batlle, A., Lombardo, M.E., Antiparasitic effect of vitamin B12 on Trypanosoma cruzi (2012) Antimicrobial Agents and Chemotherapy, 56 (10), pp. 5315-5320
• Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., Protein measurement with the Folin phenol reagent (1951) The Journal of Biological Chemistry, 193 (1), pp. 265-275. , 2-s2.0-71849104860
• Piacenza, L., Irigoin, F., Alvarez, M.N., Peluffo, G., Taylor, M.C., Kelly, J.M., Wilkinson, S.R., Radi, R., Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: Cytoprotective action of mitochondrial iron superoxide dismutase overexpression (2007) Biochemical Journal, 403 (2), pp. 323-334. , DOI 10.1042/BJ20061281
• Steenkamp, D.J., Thiol metabolism of the trypanosomatids as potential drug targets (2002) IUBMB Life, 53 (4-5), pp. 243-248. , DOI 10.1080/15216540212649
• Muller, S., Liebau, E., Walter, R.D., Krauth-Siegel, R.L., Thiol-based redox metabolism of protozoan parasites (2003) Trends in Parasitology, 19 (7), pp. 320-328. , DOI 10.1016/S1471-4922(03)00141-7
• Smirlis, D., Duszenko, M., Ruiz, A.J., Scoulica, E., Bastien, P., Fasel, N., Soteriadou, K., Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death (2010) Parasites and Vectors, 3 (1), pp. 107-121. , 2-s2.0-78349249826

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