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protein stability

"Protein stabilization by RSUME accounts for PTTG pituitary tumor abundance and oncogenicity" (2018) Fuertes, M.;Sapochnik, M.;Tedesco, L. (...)Arzt, E. Endocrine-Related Cancer. 25(6):665-676

"Frustration, function and folding" (2018) Ferreiro, D.U.; Komives, E.A.; Wolynes, P.G. Current Opinion in Structural Biology. 48:68-73

"Hidden Structural Codes in Protein Intrinsic Disorder" (2017) Borkosky, S.S.;Camporeale, G.;Chemes, L.B. (...)De Prat Gay, G. Biochemistry. 56(41):5560-5569

"Functional interaction between co-expressed MAGE-A proteins" (2017) Laiseca, J.E.;Ladelfa, M.F.;Cotignola, J. (...)Monte, M. PLoS ONE. 12(5)

"Structural coalescence underlies the aggregation propensity of a β-barrel protein motif" (2017) Angelani, C.R.; Caramelo, J.J.; Curto, L.M.; Delfino, J.M. PLoS ONE. 12(2)

"Inferring repeat-protein energetics from evolutionary information" (2017) Espada, R.;Parra, R.G.;Mora, T. (...)Ferreiro, D.U. PLoS Computational Biology. 13(6)

"Modulation of the pH Stability of Influenza Virus Hemagglutinin: A Host Cell Adaptation Strategy" (2016) Di Lella, S.; Herrmann, A.; Mair, C.M. Biophysical Journal. 110(11):2293-2301

"Alternative Conformations of Cytochrome c: Structure, Function, and Detection" (2016) Hannibal, L.;Tomasina, F.;Capdevila, D.A. (...)Radi, R. Biochemistry. 55(3):407-428

"Structure-based activity prediction of CYP21A2 stability variants: A survey of available gene variations" (2016) Bruque, C.D.;Delea, M.;Fernández, C.S. (...)Dain, L. Scientific Reports. 6

"miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga" (2016) De Lella Ezcurra, A.L.;Bertolin, A.P.;Kim, K. (...)Wappner, P. PLoS Genetics. 12(5)

"Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor-1" (2016) Abán, C.;Martinez, N.;Carou, C. (...)Farina, M. Apoptosis. 21(10):1094-1105

"Prediction of spontaneous protein deamidation from sequence-derived secondary structure and intrinsic disorder" (2015) Lorenzo, J.R.; Alonso, L.G.; Sánchez, I.E. PLoS ONE. 10(12)

"Role of RSUME in inflammation and cancer" (2015) Antico Arciuch, V.G.; Tedesco, L.; Fuertes, M.; Arzt, E. FEBS Letters. 589(22):3330-3335

"The E. Coli thioredoxin folding mechanism: The key role of the C-terminal helix" (2015) Vazquez, D.S.;Sánchez, I.E.;Garrote, A. (...)Santos, J. Biochimica et Biophysica Acta - Proteins and Proteomics. 1854(2):127-137

"Repeat proteins challenge the concept of structural domains" (2015) Espada, R.;Parra, R.G.;Sippl, M.J. (...)Ferreiro, D.U. Biochemical Society Transactions. 43:844-849

"Molecular basis of thermal stability in truncated (2/2) hemoglobins" (2014) Bustamante, J.P.;Bonamore, A.;Nadra, A.D. (...)Boechi, L. Biochimica et Biophysica Acta - General Subjects. 1840(7):2281-2288

"Interacting proteins of protein kinase A regulatory subunit in Saccharomyces cerevisiae" (2014) Galello, F.; Moreno, S.; Rossi, S. Journal of Proteomics. 109:261-275

"Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain" (2014) Aran, M.;Smal, C.;Pellizza, L. (...)Cicero, D.O. Proteins: Structure, Function and Bioinformatics. 82(11):3062-3078

"CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions" (2014) Ogara, M.F.;Belluscio, L.M.;de la Fuente, V. (...)Cánepa, E.T. Biochimica et Biophysica Acta - Molecular Cell Research. 1843(7):1309-1324

"Interplay of the H-bond donor-acceptor role of the distal residues in hydroxyl ligand stabilization of Thermobifida fusca truncated hemoglobin" (2014) Nicoletti, F.P.;Bustamante, J.P.;Droghetti, E. (...)Smulevich, G. Biochemistry. 53(51):8021-8030

"Folding of a cyclin box: Linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor ab pocket domain" (2013) Chemes, L.B.; Noval, M.G.; Sánchez, I.E.; De Prat-Gay, G. Journal of Biological Chemistry. 288(26):18923-18938

"The use of alternative polyadenylation sites renders integrin β1 (Itgb1) mRNA isoforms with differential stability during mammary gland development" (2013) Naipauer, J.;Gattelli, A.;Degese, M.S. (...)Coso, O.A. Biochemical Journal. 454(2):345-357

"The allosteric modulation of thyroxine-binding globulin affinity is entropy driven" (2013) Petruk, A.A.; Labanda, M.S.; Álvarez, R.M.S.; Marti, M.A. Biochimica et Biophysica Acta - General Subjects. 1830(6):3570-3577

"Quaternary structure effects on the hexacoordination equilibrium in rice hemoglobin rHb1: Insights from molecular dynamics simulations" (2013) Morzan, U.N.; Capece, L.; Marti, M.A.; Estrin, D.A. Proteins: Structure, Function and Bioinformatics. 81(5):863-873

"RapA2 is a calcium-binding lectin composed of two highly conserved cadherin-like domains that specifically recognize rhizobium leguminosarum acidic exopolysaccharides" (2013) Abdian, P.L.; Caramelo, J.J.; Ausmees, N.; Zorreguieta, A. Journal of Biological Chemistry. 288(4):2893-2904

"Proteasome-mediated turnover of arabidopsis MED25 is coupled to the activation of FLOWERING LOCUS T transcription" (2012) Iñigo, S.; Giraldez, A.N.; Chory, J.; Cerdán, P.D. Plant Physiology. 160(3):1662-1673

"Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals" (2012) Borsarelli, C.D.;Falomir-Lockhart, L.J.;Ostatná, V. (...)Jovin, T.M. Free Radical Biology and Medicine. 53(4):1004-1015

"Topology and dynamics of the zebrafish segmentation clock core circuit" (2012) Schröter, C.;Ares, S.;Morelli, L.G. (...)Oates, A.C. PLoS Biology. 10(7):11

"Ordered self-assembly mechanism of a spherical oncoprotein oligomer triggered by zinc removal and stabilized by an intrinsically disordered domain" (2012) Smal, C.;Alonso, L.G.;Wetzler, D.E. (...)de Prat Gay, G. PLoS ONE. 7(5)

"Regulating the regulators: Serine/arginine-rich proteins under scrutiny" (2012) Risso, G.;Pelisch, F.;Quaglino, A. (...)Srebrow, A. IUBMB Life. 64(10):809-816

"Protein Stability and Dynamics Modulation: The Case of Human Frataxin" (2012) Roman, E.A.;Faraj, S.E.;Gallo, M. (...)Santos, J. PLoS ONE. 7(9)

"Interactions between β-lactoglobulin and casein glycomacropeptide on foaming" (2012) Martinez, M.J.; Carrera Sánchez, C.; Rodríguez Patino, J.M.; Pilosof, A.M.R. Colloids and Surfaces B: Biointerfaces. 89(1):234-241

"Accumulation pattern of dehydrins during sugarcane (var. SP80.3280) somatic embryogenesis" (2012) Burrieza, H.P.;López-Fernández, M.P.;Chiquieri, T.B. (...)Maldonado, S. Plant Cell Reports. 31(12):2139-2149

"Structure-based analysis of five novel disease-causing mutations in 21-hydroxylase-deficient patients" (2011) Minutolo, C.;Nadra, A.D.;Fernández, C. (...)Dain, L. PLoS ONE. 6(1)

"Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain" (2011) Devries, I.; Ferreiro, D.U.; Sánchez, I.E.; Komives, E.A. Journal of Molecular Biology. 408(1):163-176

"Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo" (2011) Stigliano, I.D.;Alculumbre, S.G.;Labriola, C.A. (...)D'Alessio, C. Molecular Biology of the Cell. 22(11):1810-1823

"The respiratory syncytial virus transcription antiterminator M 2-1 is a highly stable, zinc binding tetramer with strong pH-dependent dissociation and a monomeric unfolding intermediate" (2011) Esperante, S.A.; Chemes, L.B.; Sánchez, I.E.; De Prat-Gay, G. Biochemistry. 50(40):8529-8539

"The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events" (2010) Galigniana, M.D.;Erlejman, A.G.;Monte, M. (...)Piwien-Pilipuk, G. Molecular and Cellular Biology. 30(5):1285-1298

"Protein deterioration and longevity of quinoa seeds during long-term storage" (2010) Castellión, M.; Matiacevich, S.; Buera, P.; Maldonado, S. Food Chemistry. 121(4):952-958

"Molecular basis of coupled protein and electron transfer dynamics of cytochrome c in biomimetic complexes" (2010) Alvarez-Paggi, D.;Martín, D.F.;Debiase, P.M. (...)Murgida, D.H. Journal of the American Chemical Society. 132(16):5769-5778

"E2F1 transcription is induced by genotoxic stress through ATM/ATR activation" (2009) Carcagno, A.L.;Ogara, M.F.;Sonzogni, S.V. (...)Cánepa, E.T. IUBMB Life. 61(5):537-543

"Potato Virus X Coat Protein Fusion to Human Papillomavirus 16 E7 Oncoprotein Enhance Antigen Stability and Accumulation in Tobacco Chloroplast" (2009) Morgenfeld, M.;Segretin, M.E.;Wirth, S. (...)Bravo-Almonacid, F. Molecular Biotechnology. 43(3):243-249

"Chromophore structure of cyanobacterial phytochrome Cph1 in the Pr state: Reconciling structural and spectroscopic data by QM/MM calculations" (2009) Mroginski, M.A.;Von Stetten, D.;Escobar, F.V. (...)Hildebrandt, P. Biophysical Journal. 96(10):4153-4163

"Post-translational processing, metabolic stability and catalytic efficiency of oat arginine decarboxylase expressed in Trypanosoma cruzi epimastigotes" (2009) Serra, M.P.; Senn, A.M.; Algranati, I.D. Experimental Parasitology. 122(3):169-176

"Effects of phosphatidylethanolamine glycation on lipid-protein interactions and membrane protein thermal stability" (2008) Levi, V.;Villamil Giraldo, A.M.;Castello, P.R. (...)González Flecha, F.L. Biochemical Journal. 416(1):145-152

"Induction of long-term memory by exposure to novelty requires protein synthesis: Evidence for a behavioral tagging" (2007) Moncada, D.; Viola, H. Journal of Neuroscience. 27(28):7476-7481

"RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia" (2007) Carbia-Nagashima, A.;Gerez, J.;Perez-Castro, C. (...)Arzt, E. Cell. 131(2):309-323

"A yeast sterol carrier protein with fatty-acid and fatty-acyl-CoA binding activity" (2006) Ferreyra, R.G.;Burgardt, N.I.;Milikowski, D. (...)Ermácora, M.R. Archives of Biochemistry and Biophysics. 453(2):197-206

"The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-α /Sima" (2005) Dekanty, A.;Lavista-Llanos, S.;Irisarri, M. (...)Wappner, P. Journal of Cell Science. 118(23):5431-5441

"Ligand-induced thermostability in proteins: Thermodynamic analysis of ANS-albumin interaction" (2005) Celej, M.S.;Dassie, S.A.;Freire, E. (...)Fidelio, G.D. Biochimica et Biophysica Acta - Proteins and Proteomics. 1750(2):122-133

"Engineering of a polymeric bacterial protein as a scaffold for the multiple display of peptides" (2004) Laplagne, D.A.;Zylberman, V.;Ainciart, N. (...)Goldbaum, F.A. Proteins: Structure, Function and Genetics. 57(4):820-828

"The HPV16 E7 Viral Oncoprotein Self-Assembles into Defined Spherical Oligomers" (2004) Alonso, L.G.;García-Alai, M.M.;Smal, C. (...)De Prat-Gay, G. Biochemistry. 43(12):3310-3317

"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746

"The receptor kinases LePRK1 and LePRK2 associate in pollen and when expressed in yeast, but dissociate in the presence of style extract" (2003) Wengier, D.;Valsecchi, I.;Cabanas, M.L. (...)Muschietti, J. Proceedings of the National Academy of Sciences of the United States of America. 100(11):6860-6865

"Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: Regulation by epidermal growth factor and the expression of Bcl-2-related genes" (2002) Parborell, F.;Pecci, A.;Gonzalez, O. (...)Tesone, M. Biology of Reproduction. 67(2):481-486

"Expression of the human RNA-binding protein HuR in Trypanosoma brucei increases the abundance of mRNAs containing AU-rich regulatory elements" (2002) Quijada, L.;Guerra-Giraldez, C.;Drozdz, M. (...)Clayton, C. Nucleic Acids Research. 30(20):4414-4424

"High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding partners" (2002) Alonso, L.G.;García-Alai, M.M.;Nadra, A.D. (...)De Prat-Gay, G. Biochemistry. 41(33):10510-10518

"Three-dimensional solution structure and stability of thioredoxin m from spinach" (2001) Neira, J.L.;González, C.;Toiron, C. (...)Rico, M. Biochemistry. 40(50):15246-15256

"Viability and thermal stability of a strain of Saccharomyces cerevisiae freeze-dried in different sugar and polymer matrices" (1999) Buera, M.P.; Lodato, P.; Segovia de Huergo, M. Applied Microbiology and Biotechnology. 52(2):215-220

"Stable ornithine decarboxylase in promastigotes of Leishmania mexicana" (1989) Sanchez, C.P.; Gonzalez, N.S.; Algranati, I.D. Biochemical and Biophysical Research Communications. 161(2):754-761