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Mycobacterium tuberculosis

145

"New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach" (2019) Gil, M.;Lima, A.;Rivera, B. (...)Durán, R. Journal of Proteomics. 192:321-333

"Fluoromycobacteriophages can detect viable Mycobacterium tuberculosis and determine phenotypic rifampicin resistance in 3-5 days from sputum collection" (2018) Rondón, L.;Urdániz, E.;Latini, C. (...)Piuri, M. Frontiers in Microbiology. 9(JUL)

"Reactive nitrogen and oxygen species: Friend or foe in the tuberculosis fight" (2018) Galizia, J.; Martí, M.A. Tuberculosis. 113:175-176

"Structural and mechanistic comparison of the Cyclopropane Mycolic Acid Synthases (CMAS) protein family of Mycobacterium tuberculosis" (2018) Defelipe, L.A.; Osman, F.; Marti, M.A.; Turjanski, A.G. Biochemical and Biophysical Research Communications. 498(2):288-295

"Target-Pathogen: A structural bioinformatic approach to prioritize drug targets in pathogens" (2018) Sosa, E.J.;Burguener, G.;Lanzarotti, E. (...)Fernández Do Porto, D. Nucleic Acids Research. 46(D1):D413-D418

"Elevated cyclic AMP inhibits mycobacterium tuberculosis-stimulated T-cell IFN-γ secretion through type I protein kinase A" (2018) Chung, Y.-T.;Pasquinelli, V.;Jurado, J.O. (...)Samten, B. Journal of Infectious Diseases. 217(11):1821-1831

"Efficient production of glycosylated and non-glycosylated mycobacterium tuberculosis antigen 85B fused to PVX coat protein in Nicotiana benthamiana plants" (2018) González, P.A.; Puccio, F.D.; Zelada, A.M. American Journal of Biochemistry and Biotechnology. 14(4):238-246

"Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead" (2018) Grotz, E.;Tateosian, N.;Amiano, N. (...)Moretton, M.A. Pharmaceutical Research. 35(11)

"The IFNG rs1861494 single nucleotide polymorphism is associated with protection against tuberculosis disease in Argentina" (2018) Rolandelli, A.;Pellegrini, J.M.;Amiano, N.O. (...)García, V.E. Genes. 9(1)

"Evaluation of nitroxyl donors’ effect on mycobacteria" (2018) Galizia, J.;Acosta, M.P.;Urdániz, E. (...)Piuri, M. Tuberculosis. 109:35-40

"Effect of the BTK inhibitor ibrutinib on macrophage- and γδ T cell-mediated response against Mycobacterium tuberculosis" (2018) Colado, A.;Genoula, M.;Cougoule, C. (...)Borge, M. Blood Cancer Journal. 8(11)

"Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses" (2017) Hernández Del Pino, R.E.;Pellegrini, J.M.;Rovetta, A.I. (...)Garciá, V.E. Immunology and Cell Biology. 95(8):716-728

"Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain" (2017) Bigi, M.M.;Lopez, B.;Blanco, F.C. (...)Soria, M.A. Tuberculosis. 103:28-36

"IL17A augments autophagy in Mycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease" (2017) Tateosian, N.L.;Pellegrini, J.M.;Amiano, N.O. (...)García, V.E. Autophagy. 13(7):1191-1204

"Theoretical insights into the reaction and inhibition mechanism of metal-independent retaining glycosyltransferase responsible for mycothiol biosynthesis" (2017) Capurro, J.I.B.;Hopkins, C.W.;Sottile, G.P. (...)Marti, M.A. Journal of Physical Chemistry B. 121(3):471-478

"The N-terminal pre-A region of Mycobacterium tuberculosis 2/2HbN promotes NO-dioxygenase activity" (2016) Pesce, A.;Bustamante, J.P.;Bidon-Chanal, A. (...)Nardini, M. FEBS Journal. 283(2):305-322

"Rapid whole-cell assay of antitubercular drugs using second-generation Fluoromycobacteriophages" (2016) Urdániz, E.;Rondón, L.;Martí, M.A. (...)Piuri, M. Antimicrobial Agents and Chemotherapy. 60(5):3253-3256

"Bacterial strategies to maintain zinc metallostasis at the host-pathogen interface" (2016) Capdevila, D.A.; Wang, J.; Giedroc, D.P. Journal of Biological Chemistry. 291(40):20858-20868

"A whole genome bioinformatic approach to determine potential latent phase specific targets in Mycobacterium tuberculosis" (2016) Defelipe, L.A.;Do Porto, D.F.;Pereira Ramos, P.I. (...)Marti, M.A. Tuberculosis. 97:181-192

"PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase" (2016) Reyes, A.M.;Vazquez, D.S.;Zeida, A. (...)Trujillo, M. Free Radical Biology and Medicine. 101:249-260

"Steered Molecular Dynamics Methods Applied to Enzyme Mechanism and Energetics" (2016) Ramírez, C.L.; Martí, M.A.; Roitberg, A.E. Methods in Enzymology. 578:123-143

"Ligand uptake in Mycobacterium tuberculosis truncated hemoglobins is controlled by both internal tunnels and active site water molecules" (2015) Boechi, L.;Boron, I.;Bustamante, J.P. (...)Marti, M.A. F1000Research. 4

"Molecular Basis of Hydroperoxide Specificity in Peroxiredoxins: The Case of AhpE from Mycobacterium tuberculosis" (2015) Zeida, A.;Reyes, A.M.;Lichtig, P. (...)Trujillo, M. Biochemistry. 54(49):7237-7247

"Efficient calculation of enzyme reaction free energy profiles using a hybrid differential relaxation algorithm: Application to mycobacterial zinc hydrolases" (2015) Romero, J.M.;Martin, M.;Ramirez, C.L. (...)Karabencheva-Christova T. Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions, 2015. 100:33-65

"A Mycobacterium tuberculosis Dormancy Antigen Differentiates Latently Infected Bacillus Calmette-Guérin-vaccinated Individuals" (2015) Peña, D.;Rovetta, A.I.;Hernández Del Pino, R.E. (...)García, V.E. EBioMedicine. 2(8):884-890

"Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: Role of the CD loop and Pre-A motif in electron cycling" (2014) Singh, S.;Thakur, N.;Oliveira, A. (...)Dikshit, K.L. Journal of Biological Chemistry. 289(31):21573-21583

"The extraordinary catalytic ability of peroxiredoxins: A combined experimental and QM/MM study on the fast thiol oxidation step" (2014) Zeida, A.;Reyes, A.M.;Lebrero, M.C.G. (...)Estrin, D.A. Chemical Communications. 50(70):10070-10073

"IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis" (2014) Rovetta, A.I.;Peña, D.;Hernández Del Pino, R.E. (...)García, V.E. Autophagy. 10(12):2109-2121

"TuberQ: A Mycobacterium tuberculosis protein druggability database" (2014) Radusky, L.;Defelipe, L.A.;Lanzarotti, E. (...)Turjanski, A.G. Database. 2014

"Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis" (2014) Bos, K.I.;Harkins, K.M.;Herbig, A. (...)Krause, J. Nature. 514(7253):494-497

"Molecular basis of thermal stability in truncated (2/2) hemoglobins" (2014) Bustamante, J.P.;Bonamore, A.;Nadra, A.D. (...)Boechi, L. Biochimica et Biophysica Acta - General Subjects. 1840(7):2281-2288

"QM/MM study of the C-C coupling reaction mechanism of CYP121, an essential Cytochrome p450 of Mycobacterium tuberculosis" (2014) Dumas, V.G.;Defelipe, L.A.;Petruk, A.A. (...)Marti, M.A. Proteins: Structure, Function and Bioinformatics. 82(6):1004-1021

"Bayesian Approach to Model CD137 Signaling in Human M. tuberculosis In Vitro Responses" (2013) Fernández Do Porto, D.A.;Auzmendi, J.;Peña, D. (...)Moffatt, L. PLoS ONE. 8(2)

"QM/MM study of the C-C coupling reaction mechanism of CYP121, an essential Fytochrome p450 of Mycobacterium tuberculosis" (2013) Dumas, V.G.;Defelipe, L.A.;Petruk, A.A. (...)Marti, M.A. Proteins: Structure, Function and Bioinformatics

"Phosphorylation of mitogen-activated protein kinases contributes to interferon γ production in response to mycobacterium tuberculosis" (2013) Pasquinelli, V.;Rovetta, A.I.;Alvarez, I.B. (...)García, V.E. Journal of Infectious Diseases. 207(2):340-350

"CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis" (2012) Fernández Do Porto, D.A.;Jurado, J.O.;Pasquinelli, V. (...)García, V.E. Immunology and Cell Biology. 90(4):449-456

"Role of PheE15 Gate in Ligand Entry and Nitric Oxide Detoxification Function of Mycobacterium tuberculosis Truncated Hemoglobin N" (2012) Oliveira, A.;Singh, S.;Bidon-Chanal, A. (...)Luque, F.J. PLoS ONE. 7(11)

"The peculiar heme pocket of the 2/2 hemoglobin of cold-adapted Pseudoalteromonas haloplanktis TAC125" (2011) Howes, B.D.;Giordano, D.;Boechi, L. (...)Smulevich, G. Journal of Biological Inorganic Chemistry. 16(2):299-311

"Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: Kinetics and mechanisms of oxidation and overoxidation" (2011) Reyes, A.M.;Hugo, M.;Trostchansky, A. (...)Trujillo, M. Free Radical Biology and Medicine. 51(2):464-473

"Synthesis of arabinofuranose branched galactofuran tetrasaccharides, constituents of mycobacterial arabinogalactan" (2011) Gandolfi-Donadío, L.; Santos, M.; De Lederkremer, R.M.; Gallo-Rodriguez, C. Organic and Biomolecular Chemistry. 9(7):2085-2097

"Evaluation of fluoromycobacteriophages for detecting drug resistance in Mycobacterium tuberculosis" (2011) Rondón, L.;Piuri, M.;Jacobs Jr., W.R. (...)Takiff, H.E. Journal of Clinical Microbiology. 49(5):1838-1842

"A dynamic analysis of tuberculosis dissemination to improve control and surveillance" (2010) Zorzenon dos Santos, R.M.;Amador, A.;de Souza, W.V. (...)Silva, C.L. PLoS ONE. 5(11)

"Exploring the nitric oxide detoxification mechanism of mycobacterium tuberculosis truncated haemoglobin N" (2009) Bidon-Chanal, A.; Martí, M.A.; Estrín, D.A.; Luque, F.J. NATO Security through Science Series C: Environmental Security:33-47

"Exploring the nitric oxide detoxification mechanism of mycobacterium tuberculosis truncated haemoglobin N" (2009) Bidon-Chanal, A.; Martí, M.A.; Estrín, D.A.; Luque, F.J. NATO Science for Peace and Security Series A: Chemistry and Biology:33-47

"Role of pre-A motif in nitric oxide scavenging by truncated hemoglobin, HbN, of Mycobacterium tuberculosis" (2009) Lama, A.;Pawaria, S.;Bidon-Chanal, A. (...)Dikshit, K.L. Journal of Biological Chemistry. 284(21):14457-14468

"Synthesis of a tetrasaccharide fragment of mycobacterial arabinogalactan" (2008) Gandolfi-Donadío, L.; Gallo-Rodriguez, C.; de Lederkremer, R.M. Carbohydrate Research. 343(10-11):1870-1875

"Boza, a natural source of probiotic lactic acid bacteria" (2008) Todorov, S.D.;Botes, M.;Guigas, C. (...)Dicks, L.M.T. Journal of Applied Microbiology. 104(2):465-477

"Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis" (2008) Jurado, J.O.;Alvarez, I.B.;Pasquinelli, V. (...)García, V.E. Journal of Immunology. 181(1):116-125

"Mechanism of product release in NO detoxification from Mycobacterium tuberculosis truncated hemoglobin N" (2008) Martí, M.A.;Bidon-Chanal, A.;Crespo, A. (...)Estrin, D.A. Journal of the American Chemical Society. 130(5):1688-1693

"Nitric Oxide Reactivity with Globins as Investigated Through Computer Simulation" (2008) Marti, M.A.;Capece, L.;Bidon-Chanal, A. (...)Estrin, D.A. Methods in Enzymology. 437:477-498

"Structural determinants of ligand migration in Mycobacterium tuberculosis truncated hemoglobin O" (2008) Boechi, L.;Martí, M.A.;Milani, M. (...)Estrin, D.A. Proteins: Structure, Function and Genetics. 73(2):372-379

"Dynamical regulation of ligand migration by a gate-opening molecular switch in truncated hemoglobin-N from Mycobacterium tuberculosis" (2007) Bidon-Chanal, A.; Martí, M.A.; Estrin, D.A.; Luque, F.J. Journal of the American Chemical Society. 129(21):6782-6788

"Ligand-induced dynamical regulation of NO conversion in Mycobacterium tuberculosis truncated hemoglobin-N" (2006) Bidon-Chanal, A.;Martí, M.A.;Crespo, A. (...)Estrin, D.A. Proteins: Structure, Function and Genetics. 64(2):457-464

"Facile synthesis of α-D-Araf-(1→5)-D-Galf, the linker unit of the arabinan to the galactan in Mycobacterium tuberculosis" (2006) Gandolfi-Donadío, L.; Gallo-Rodriguez, C.; De Lederkremer, R.M. Canadian Journal of Chemistry. 84(4):486-491

"Expression of tuberculosis antigen ESAT-6 in Nicotiana tabacum using a potato virus X-based vector" (2006) Zelada, A.M.;Calamante, G.;de la Paz Santangelo, M. (...)Cataldi, A. Tuberculosis. 86(3-4 SPEC ISS):263-267

"Dioxygen affinity in heme proteins investigated by computer simulation" (2006) Marti, M.A.;Crespo, A.;Capece, L. (...)Estrin, D.A. Journal of Inorganic Biochemistry. 100(4):761-770

"Theoretical study of the truncated hemoglobin HbN: Exploring the molecular basis of the NO detoxification mechanism" (2005) Crespo, A.;Martí, M.A.;Kalko, S.G. (...)Estrin, D.A. Journal of the American Chemical Society. 127(12):4433-4444

"Syntheses of β-D-Galf-(1→6)-β-D-Galf-(1→5)-D-Galf and β-D-Galf-(1→5)-β-D-Galf-(1→6)-D-Galf, trisaccharide units in the galactan of Mycobacterium tuberculosis" (2003) Gandolfi-Donadío, L.; Gallo-Rodriguez, C.; De Lederkremer, R.M. Journal of Organic Chemistry. 68(18):6928-6934

"Tuberculosis in a wild subantarctic fur seal from Argentina" (1999) Bastida, R.;Loureiro, J.;Quse, V. (...)Costa, E. Journal of Wildlife Diseases. 35(4):796-798

"D-galactofuranosylphosphonates. First synthesis of UDP-C-D- galactofuranose" (1999) Kovensky, J.; McNeil, M.; Sinaÿ, P. Journal of Organic Chemistry. 64(17):6202-6205

"Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases " (1998) Esquivel, S.P.;Vigna, L.;Velázquez, J. (...)Massini, R. Enfermedades Infecciosas y Microbiologia Clinica. 16(1):31-34

"Tuberculous arthritis in the course of connective tissue disease: Report of 4 cases" (1992) Stecher, D.R.; Gusis, S.E.; Maldonado Cocco, J.A. Journal of Rheumatology. 19(9):1418-1420

"Synthesis of galactofuranose disaccharides of biological significance" (1989) Marino, C.; Varela, O.; de Lederkremer, R.M. Carbohydrate Research. 190(1):65-76