Artículo
Esquivel, S.P.; Vigna, L.; Velázquez, J.; Cangelosi, D.; Figueiras, O.; Solari, R.; Corti, M.; Massini, R. "Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases " (1998) Enfermedades Infecciosas y Microbiologia Clinica. 16(1):31-34
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Abstract:
BACKGROUND: Acute cutaneous miliary tuberculosis is a rare form of Mycobacterium tuberculosis infection which has been described in only 25 published cases in the last 15 years. The appearance of serious disseminated forms of tuberculosis is enhanced by the severe immunodeficiency which characterizes AIDS. METHODS: Four cases are described of disseminated tuberculosis with cutaneous localization clinically described as the acute miliary form. Patients had AIDS and CD4 lymphocyte levels of < 100 cells/mm3. Diagnosis was established in all cases by scraping of cutaneous lesions and direct examination with Ziehl-Neelsen coloration. RESULTS: The 4 patients presented signs and symptoms of disseminated tuberculosis with cutaneous manifestations, without a definite pattern and with localization predominantly on the thorax. Three had BAAR-positive sputum. Multiresistant strains of Mycobacterium tuberculosis were confirmed by antibiogram. One patient infected by a strain sensitive to first-line drugs responded favorably to conventional treatment for disseminated tuberculosis. In the remaining three with multiresistant strains, the evolution of the disease was rapid and unfavorable. CONCLUSIONS: Abrupt appearance of cutaneous lesions in a patient with disseminated tuberculosis and advanced HIV-disease should raise the suspicion of its etiology. Scraping and direct examination using Ziehl-Neelsen coloration is practical, economical and non-invasive diagnostic method.
Registro:
| Documento: | Artículo |
| Título: | Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases |
| Autor: | Esquivel, S.P.; Vigna, L.; Velázquez, J.; Cangelosi, D.; Figueiras, O.; Solari, R.; Corti, M.; Massini, R. |
| Filiación: | Unidades 10/11, Pabellón 22, Hospital F.J. Muñiz, Buenos Aires, Argentina Unidad 10, Pabellón 22, Hospital F.J. Muñiz, Uspallata 2272 (CP 1152), Buenos Aires, Argentina |
| Palabras clave: | Cutaneous tuberculosis; HIV; Mycobacterium tuberculosis; tuberculostatic agent; acquired immune deficiency syndrome; adult; antibiotic sensitivity; article; case report; fatality; human; male; miliary tuberculosis; multidrug resistance; mycobacterium tuberculosis; acquired immune deficiency syndrome; miliary tuberculosis; skin tuberculosis; Acquired Immunodeficiency Syndrome; Adult; Humans; Male; Tuberculosis, Cutaneous; Tuberculosis, Miliary |
| Año: | 1998 |
| Volumen: | 16 |
| Número: | 1 |
| Página de inicio: | 31 |
| Página de fin: | 34 |
| Título revista: | Enfermedades Infecciosas y Microbiologia Clinica |
| Título revista abreviado: | Enferm. Infecc. Microbiol. Clin. |
| ISSN: | 0213005X |
| CODEN: | EIMCE |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel |
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Citas:
---------- APA ----------
Esquivel, S.P., Vigna, L., Velázquez, J., Cangelosi, D., Figueiras, O., Solari, R., Corti, M.,..., Massini, R. (1998) . Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases . Enfermedades Infecciosas y Microbiologia Clinica, 16(1), 31-34.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel [ ]
---------- CHICAGO ----------
Esquivel, S.P., Vigna, L., Velázquez, J., Cangelosi, D., Figueiras, O., Solari, R., et al. "Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases " . Enfermedades Infecciosas y Microbiologia Clinica 16, no. 1 (1998) : 31-34.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel [ ]
---------- MLA ----------
Esquivel, S.P., Vigna, L., Velázquez, J., Cangelosi, D., Figueiras, O., Solari, R., et al. "Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases " . Enfermedades Infecciosas y Microbiologia Clinica, vol. 16, no. 1, 1998, pp. 31-34.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel [ ]
---------- VANCOUVER ----------
Esquivel, S.P., Vigna, L., Velázquez, J., Cangelosi, D., Figueiras, O., Solari, R., et al. Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases . Enferm. Infecc. Microbiol. Clin. 1998;16(1):31-34.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel [ ]
