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Gene Expression Regulation, Neoplastic

"IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity" (2018) Song, M.;Sandoval, T.A.;Chae, C.-S. (...)Cubillos-Ruiz, J.R. Nature. 562(7727):423-428

"Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk" (2018) Orozco, C.A.;Martinez-Bosch, N.;Guerrero, P.E. (...)Navarro, P. Proceedings of the National Academy of Sciences of the United States of America. 115(16):E3769-E3778

"In vivo hemin conditioning targets the vascular and immunologic compartments and restrains prostate tumor development" (2017) Jaworski, F.M.;Gentilini, L.D.;Gueron, G. (...)Vazquez, E.S. Clinical Cancer Research. 23(17):5135-5148

"Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer" (2017) Ramakrishnan, S.;Hu, Q.;Krishnan, N. (...)Woloszynska-Read, A. Cell Death and Disease. 8(12)

"Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated" (2016) Bracalente, C.;Ibañez, I.L.;Berenstein, A. (...)Durán, H. Oncotarget. 7(27):41154-41171

"RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes" (2016) Recouvreux, M.S.;Grasso, E.N.;Echeverria, P.C. (...)Rubinstein, N. Oncotarget. 7(6):6552-6565

"Heme oxygenase-1 in the forefront of a multi-molecular network that governs cell-cell contacts and filopodia-induced zippering in prostate cancer" (2016) Paez, A.V.;Pallavicini, C.;Schuster, F. (...)Gueron, G. Cell death & disease. 7(12):e2570

"Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells" (2016) Castillo, L.F.;Tascón, R.;Huvelle, M.A.L. (...)Peters, M.G. Oncotarget. 7(37):60133-60154

"RSUME inhibits VHL and regulates its tumor suppressor function" (2015) Gerez, J.;Tedesco, L.;Bonfiglio, J.J. (...)Arzt, E. Oncogene. 34(37):4855-4866

"Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases" (2014) Wan, X.;Corn, P.G.;Yang, J. (...)Navone, N.M. Science Translational Medicine. 6(252)

"The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy" (2014) Orqueda, A.J.;Dansey, M.V.;Español, A. (...)Pecci, A. Biochemical Pharmacology. 89(4):526-535

"Glycans and galectins in prostate cancer biology, angiogenesis and metastasis" (2014) Compagno, D.;Gentilini, L.D.;Jaworski, F.M. (...)Laderach, D.J. Glycobiology. 24(10):899-906

"Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia" (2014) Rocha-Viegas, L.;Villa, R.;Gutierrez, A. (...)Croce, L.D. Molecular and Cellular Biology. 34(19):3765-3775

"GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration" (2012) Scolz, M.;Widlund, P.O.;Piazza, S. (...)Bird, A.W. PLoS ONE. 7(12)

"The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide" (2012) Zacarías Fluck, M.F.;Hess, L.;Salatino, M. (...)Scharovsky, O.G. Cancer Immunology, Immunotherapy. 61(4):469-480

"Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma" (2012) Croci, D.O.;Salatino, M.;Rubinstein, N. (...)Rabinovich, G.A. Journal of Experimental Medicine. 209(11):1985-2000

"Mammary differentiation induces expression of Tristetraprolin, a tumor suppressor AU-rich mRNA-binding protein" (2012) Goddio, M.V.;Gattelli, A.;Slomiansky, V. (...)Kordon, E.C. Breast Cancer Research and Treatment. 135(3):749-758

"Oral administration of fluoxetine alters the proliferation/apoptosis balance of lymphoma cells and up-regulates T cell immunity in tumor-bearing mice" (2011) Frick, L.R.;Rapanelli, M.;Arcos, M.L.B. (...)Genaro, A.M. European Journal of Pharmacology. 659(2-3):265-272

"Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer" (2011) Ferrando, M.;Gueron, G.;Elguero, B. (...)Vazquez, E. Angiogenesis. 14(4):467-479

"p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior" (2011) Rosenthal, D.T.;Iyer, H.;Escudero, S. (...)Merajver, S.D. Cancer Research. 71(20):6338-6349

"Classical membrane progesterone receptors in murine mammary carcinomas: Agonistic effects of progestins and RU-486 mediating rapid non-genomic effects" (2011) Bottino, M.C.;Cerliani, J.P.;Rojas, P. (...)Lanari, C. Breast Cancer Research and Treatment. 126(3):621-636

"c-Jun regulates phosphoinositide-dependent kinase 1 transcription: Implication for Akt and protein kinase C activities melanoma tumorigenesis" (2010) Lopez-Bergami, P.;Kim, H.;Dewing, A. (...)Ronai, Z. Journal of Biological Chemistry. 285(2):903-913

"A new paradigm for MAPK: Structural interactions of hERK1 with mitochondria in HeLa cells" (2009) Galli, S.;Jahn, O.;Hitt, R. (...)Jovin, T.M. PLoS ONE. 4(10)

"Differential gene expression in models of pituitary prolactin-producing tumoral cells" (2009) Giacomini, D.;Haedo, M.;Gerez, J. (...)Arzt, E. Hormone Research. 71(SUPPL2):88-94

"Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis" (2008) Giulianelli, S.;Cerliani, J.P.;Lamb, C.A. (...)Lanari, C. International Journal of Cancer. 123(11):2518-2531

"The Gα12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis" (2007) Martín, M.J.;Tanos, T.;García, A.B. (...)Marinissen, M.J. Journal of Biological Chemistry. 282(47):34510-34524

"Fibronectin is distinctly downregulated in murine mammary adenocarcinoma cells with high metastatic potential" (2006) Urtreger, A.J.;Werbajh, S.E.;Verrecchia, F. (...)Bal De Kier Joffé, E.D. Oncology Reports. 16(6):1403-1410

"Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation" (2006) Salatino, M.;Beguelin, W.;Peters, M.G. (...)Elizalde, P.V. Oncogene. 25(59):7723-7739

"Galectin-1: Biphasic growth regulation of Leydig tumor cells" (2006) Biron, V.A.;Iglesias, M.;Troncoso, M.F. (...)Wolfenstein-Todel, C. Glycobiology. 16(9):810-821

"Homeostatic response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle association" (2006) Castronuovo, C.C.;Sacca, P.A.;Meiss, R. (...)Vazquez, E.S. BMC Cancer. 6

"Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: A study on hCG overexpressing transgenic mice" (2005) Ahtiainen, P.;Rulli, S.B.;Shariatmadari, R. (...)Huhtaniemi, I.T. Oncogene. 24(49):7301-7309

"Aluminum exposure affects transferrin-dependent and -independent iron uptake by K562 cells" (2005) Pérez, G.;Pregi, N.;Vittori, D. (...)Nesse, A. Biochimica et Biophysica Acta - Molecular Cell Research. 1745(1):124-130

"Cell cycle arrest and modulation of HO-1 expression induced by acetyl salicylic acid in hepatocarcinogenesis" (2004) Sacca, P.; Caballero, F.; Batlle, A.; Vazquez, E. International Journal of Biochemistry and Cell Biology. 36(10):1945-1953

"Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth, and tumor development of pituitary lactosomatotrophic GH3 cells" (2003) Perez Castro, C.;Giacomini, D.;Carbia Nagashima, A. (...)Arzt, E. Endocrinology. 144(2):693-700

"Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures" (2001) Perez Castro, C.;Carbia Nagashima, A.;Páez Pereda, M. (...)Arzt, E. Journal of Endocrinology. 169(3):539-547

"Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human corticotroph pituitary adenomas" (2000) Páez Pereda, M.;Lohrer, P.;Kovalovsky, D. (...)Arzt, E. Experimental and Clinical Endocrinology and Diabetes. 108(3):202-207

"Regulation of HLA-DR antigen in monocytes from colorectal cancer patients by in vitro treatment with human recombinant interferon-γ" (2000) Novellino, P.S.;Trejo, Y.G.;Beviacqua, M. (...)Rumi, L.S. Journal of Investigational Allergology and Clinical Immunology. 10(2):90-93

"Differential expression of and responsiveness to transforming growth factor-β (TGF-β) isoforms in hormone-dependent and independent lines of mouse mammary tumors" (1999) Viegas, M.H.;Salatino, M.;Goin, M. (...)Elizalde, P.V. Cancer Detection and Prevention. 23(5):375-386

"Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells" (1997) Fernanda Ledda, M.;Adris, S.;Bravo, A.I. (...)Podhajcer, O.L. Nature Medicine. 3(2):171-176

"Interleukin-2 (IL-2) and IL-6 regulate c-fos protooncogene expression in human pituitary adenoma explants" (1996) Páez Pereda, M.;Goldberg, V.;Chervín, A. (...)Arzt, E. Molecular and Cellular Endocrinology. 124(1-2):33-42

"Transforming growth factor-β activities in 'in vivo' lines of hormone-dependent and independent mammary adenocarcinomas induced by medroxyprogesterone acetate in BALB/c mice" (1990) Elizalde, P.V.;Lanari, C.;Kordon, E. (...)Charreau, E.H. Breast Cancer Research and Treatment. 16(1):29-39