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Pituitary Neoplasms

"Programmed cell senescence: Role of IL-6 in the pituitary" (2017) Sapochnik, M.; Fuertes, M.; Arzt, E. Journal of Molecular Endocrinology. 58(4):R241-R253

"Molecular Mechanisms Underlying Pituitary Pathogenesis" (2016) Sapochnik, M.; Nieto, L.E.; Fuertes, M.; Arzt, E. Biochemical Genetics. 54(2):107-119

"Sex differences in the pituitary transforming growth factor-β1 system: Studies in a model of resistant prolactinomas" (2013) Recouvreux, M.V.;Lapyckyj, L.;Camilletti, M.A. (...)Díaz-Torga, G. Endocrinology. 154(11):4192-4205

"Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas" (2012) Shan, B.;Schaaf, C.;Schmidt, A. (...)Renner, U. Journal of Endocrinology. 214(3):389-398

"RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells" (2012) Shan, B.;Gerez, J.;Haedo, M. (...)Renner, U. Endocrine-Related Cancer. 19(1):13-27

"Inhibitory effects of antivascular endothelial growth factor strategies in experimental dopamine-resistant prolactinomas" (2011) Luque, G.M.;Perez-Millán, M.I.;Ornstein, A.M. (...)Becu-Villalobos, D. Journal of Pharmacology and Experimental Therapeutics. 337(3):766-774

"Pituitary tumors: Cell type-specific roles for BMP-4" (2010) Labeur, M.;Páez-Pereda, M.;Haedo, M. (...)Stalla, G.K. Molecular and Cellular Endocrinology. 326(1-2):85-88

"Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology" (2010) Fuertes, M.;Gerez, J.;Haedo, M. (...)Arzt, E. Frontiers of Hormone Research. 38:1-6

"Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels" (2010) Ahtiainen, P.;Sharp, V.;Rulli, S.B. (...)Huhtaniemi, I. Endocrine-Related Cancer. 17(3):611-621

"Novel medical therapies for pituitary tumors" (2010) Theodoropoulou, M.;Labeur, M.;Paez Pereda, M. (...)Stalla, G.K. Frontiers of Hormone Research. 38:158-164

"VEGF and CD31 association in pituitary adenomas" (2010) Cristina, C.;Perez-Millan, M.I.;Luque, G. (...)Becu-Villalobos, D. Endocrine Pathology. 21(3):154-160

"Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells" (2010) Schaaf, C.;Shan, B.;Onofri, C. (...)Renner, U. Neuroendocrinology. 91(2):200-210

"Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo" (2009) Schaaf, C.;Shan, B.;Buchfelder, M. (...)Renner, U. Endocrine-Related Cancer. 16(4):1339-1350

"Invasive giant prolactinoma with loss of therapeutic response to cabergoline: Expression of angiogenic markers" (2009) Mallea-Gil, M.S.;Cristina, C.;Perez-Millan, M.I. (...)Becu-Villalobos, D. Endocrine Pathology. 20(1):35-40

"Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas" (2009) Labeur, M.; Paez-Pereda, M.; Arzt, E.; Stalla, G.K. Reviews in Endocrine and Metabolic Disorders. 10(2):103-109

"Anatomical landmarks for positioning the head in preparation for the transsphenoidal approach: The spheno-sellar point" (2009) Campero, A.;Socolovsky, M.;Torino, R. (...)Rhoton, A.L. British Journal of Neurosurgery. 23(3):282-286

"Interferon-γ inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway" (2008) Labeur, M.;Refojo, D.;Wölfel, B. (...)Stalla, G.K. Journal of Endocrinology. 199(2):177-189

"PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes" (2007) Cristina, C.;Díaz-Torga, G.S.;Goya, R.G. (...)Becu-Villalobos, D. Molecular Cancer. 6

"Different kinases regulate activation of voltage-dependent calcium channels by depolarization in GH3 cells" (2007) Vela, J.; Pérez-Millán, M.I.; Becu-Villalobos, D.; Díaz-Torga, G. American Journal of Physiology - Cell Physiology. 293(3):C951-C959

"Dopaminergic D2 receptor knockout mouse: An animal model of prolactinoma" (2006) Cristina, C.;García-Tornadú, I.;Díaz-Torga, G. (...)Bronstein M. Frontiers of Hormone Research. 35:50-63

"Bone morphogenetic protein-4 inhibits corticotroph tumor cells: Involvement in the retinoic acid inhibitory action" (2006) Giacomini, D.;Páez-Pereda, M.;Theodoropoulou, M. (...)Arzt, E. Endocrinology. 147(1):247-256

"Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: Detection of a non-endothelial function of VEGF in pituitary tumours" (2006) Onofri, C.;Theodoropoulou, M.;Losa, M. (...)Renner, U. Journal of Endocrinology. 191(1):249-261

"Retinoic acid as a novel medical therapy for Cushing's disease in dogs" (2006) Castillo, V.;Giacomini, D.;Páez-Pereda, M. (...)Arzt, E. Endocrinology. 147(9):4438-4444

"Signaling processes in tumoral neuroendocrine pituitary cells as potential targets for therapeutic drugs" (2005) Paez-Pereda, M.;Giacomini, D.;Echenique, C. (...)Arzt, E. Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5(3):259-267

"Estradiol Stimulates Vascular Endothelial Growth Factor and Interleukin-6 in Human Lactotroph and Lactosomatotroph Pituitary Adenomas" (2004) Onofri, C.;Carbia Nagashima, A.;Schaaf, L. (...)Arzt, E. Experimental and Clinical Endocrinology and Diabetes. 112(1):18-23

"Involvement of the gp130 cytokine transducer in MtT/S pituitary somatotroph tumour development in an autocrine-paracrine model" (2004) Graciarena, M.;Carbia-Nagashima, A.;Onofri, C. (...)Arzt, E. European Journal of Endocrinology. 151(5):595-604

"Functional in vitro studies on the role and regulation of interleukin-6 in human somatotroph pituitary adenomas" (2003) Thiele, J.-O.;Lohrer, P.;Schaaf, L. (...)Renner, U. European Journal of Endocrinology. 149(5):455-461

"New mechanisms involved in the pathogenesis of pituitary adenomas " (2003) Giacomini, D.;Paez-Pereda, M.;Refojo, D. (...)Arzt, E. Medicina. 63(2):147-150

"Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth, and tumor development of pituitary lactosomatotrophic GH3 cells" (2003) Perez Castro, C.;Giacomini, D.;Carbia Nagashima, A. (...)Arzt, E. Endocrinology. 144(2):693-700

"Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk" (2003) Páez-Pereda, M.;Giacomini, D.;Refojo, D. (...)Arzt, E. Proceedings of the National Academy of Sciences of the United States of America. 100(3):1034-1039

"Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells" (2001) Kuchenbauer, F.;Hopfner, U.;Stalla, J. (...)Páez-Pereda, M. Molecular and Cellular Endocrinology. 175(1-2):141-148

"Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures" (2001) Perez Castro, C.;Carbia Nagashima, A.;Páez Pereda, M. (...)Arzt, E. Journal of Endocrinology. 169(3):539-547

"High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells" (2000) Pereda, M.P.;Ledda, M.F.;Goldberg, V. (...)Stalla, G.K. Journal of Clinical Endocrinology and Metabolism. 85(1):263-269

"Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human corticotroph pituitary adenomas" (2000) Páez Pereda, M.;Lohrer, P.;Kovalovsky, D. (...)Arzt, E. Experimental and Clinical Endocrinology and Diabetes. 108(3):202-207

"Interleukin-1β enhances interleukin-1 receptor antagonist content in human somatotroph adenoma cell cultures" (1998) Sauer, J.;Renner, U.;Hopfner, U. (...)Stalla, G.K. Journal of Clinical Endocrinology and Metabolism. 83(7):2429-2434

"Interleukin-2 (IL-2) and IL-6 regulate c-fos protooncogene expression in human pituitary adenoma explants" (1996) Páez Pereda, M.;Goldberg, V.;Chervín, A. (...)Arzt, E. Molecular and Cellular Endocrinology. 124(1-2):33-42