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gene deletion

"Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk" (2018) Orozco, C.A.;Martinez-Bosch, N.;Guerrero, P.E. (...)Navarro, P. Proceedings of the National Academy of Sciences of the United States of America. 115(16):E3769-E3778

"Hidden Structural Codes in Protein Intrinsic Disorder" (2017) Borkosky, S.S.;Camporeale, G.;Chemes, L.B. (...)De Prat Gay, G. Biochemistry. 56(41):5560-5569

"The role of PKA in the translational response to heat stress in Saccharomyces cerevisiae" (2017) Barraza, C.E.;Solari, C.A.;Marcovich, I. (...)Portela, P. PLoS ONE. 12(10)

"Germline and somatic mutations in cortical malformations: Molecular defects in Argentinean patients with neuronal migration disorders" (2017) González-Morón, D.;Vishnopolska, S.;Consalvo, D. (...)Kauffman, M.A. PLoS ONE. 12(9)

"Deletion of pilA, a Minor Pilin-Like Gene, from Xanthomonas citri subsp. citri Influences Bacterial Physiology and Pathogenesis" (2016) Petrocelli, S.;Arana, M.R.;Cabrini, M.N. (...)Orellano, E.G. Current Microbiology. 73(6):904-914

"Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling" (2016) Lemos, J.C.;Friend, D.M.;Kaplan, A.R. (...)Alvarez, V.A. Neuron. 90(4):824-838

"Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: Implications for fertility disorders" (2016) Brukman, N.G.;Miyata, H.;Torres, P. (...)Cuasnicú, P.S. Molecular Human Reproduction. 22(4):240-251

"Deletion of A44L, A46R and C12L vaccinia virus genes from the MVA genome improved the vector immunogenicity by modifying the innate immune response generating enhanced and optimized specific T-cell responses" (2016) Holgado, M.P.;Falivene, J.;Maeto, C. (...)Gherardi, M.M. Viruses. 8(5)

"Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of Cocaine" (2016) Dobbs, L.K.;Kaplan, A.R.;Lemos, J.C. (...)Alvarez, V.A. Neuron. 90(5):1100-1113

"Whole genome sequencing reveals a de novo SHANK3 mutation in familial autism spectrum disorder" (2015) Nemirovsky, S.I.;Córdoba, M.;Zaiat, J.J. (...)Kauffman, M.A. PLoS ONE. 10(2)

"Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells" (2015) Benatar, A.F.;García, G.A.;Bua, J. (...)Gómez, K.A. PLoS Neglected Tropical Diseases. 9(10)

"Acute intermittent porphyria in argentina: An update" (2015) Cerbino, G.N.;Gerez, E.N.;Varela, L.S. (...)Rossetti, M.V. BioMed Research International. 2015

"PKA-chromatin association at stress responsive target genes from Saccharomyces cerevisiae" (2015) Baccarini, L.;Martínez-Montañés, F.;Rossi, S. (...)Portela, P. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1849(11):1329-1339

"A rhomboid protease gene deletion affects a novel oligosaccharide N-linked to the S-layer glycoprotein of Haloferax volcanii" (2014) Parente, J.;Casabuono, A.;Ferrari, M.C. (...)Giménez, M.I. Journal of Biological Chemistry. 289(16):11304-11317

"Molecular diagnosis of dystrophinopathies using a multi-technique analysis algorithm" (2014) Luce, L.N.;Ottaviani, D.;Ferrer, M. (...)Giliberto, F. Muscle and Nerve. 49(2):249-256

"Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys" (2014) Mazzitelli, L.R.; Adamo, H.P. Journal of Biological Chemistry. 289(15):10761-10768

""A La Recherche" of functions for the spore protein SASP-E from Bacillus subtilis" (2013) Ruzal, S.M.; Bustos, P.L.; Sánchez-Rivas, C. Journal of Microbiology and Biotechnology. 23(1):15-21

"Application of BRED technology to construct recombinant D29 reporter phage expressing EGFP" (2013) da Silva, J.L.;Piuri, M.;Broussard, G. (...)Hirata, M.H. FEMS Microbiology Letters. 344(2):166-172

"Anr, the anaerobic global regulator, modulates the redox state and oxidative stress resistance in pseudomonas extremaustralis" (2013) Tribelli, P.M.; Nikel, P.I.; Oppezzo, O.J.; López, N.I. Microbiology (United Kingdom). 159(2):259-268

"Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning" (2012) Fuentes, F.;Zimmer, D.;Atienza, M. (...)Arregui, C.O. PLoS ONE. 7(7)

"Manipulation of the anoxic metabolism in escherichia coli by ArcB deletion variants in the ArcBA two-component system" (2012) Bidart, G.N.;Ruiz, J.A.;de Almeida, A. (...)Nikel, P.I. Applied and Environmental Microbiology. 78(24):8784-8794

"Molecular analysis of the UROD gene in 17 Argentinean patients with familial porphyria cutanea tarda: Characterization of four novel mutations" (2012) Méndez, M.;Rossetti, M.V.;Gómez-Abecia, S. (...)Enríquez de Salamanca, R. Molecular Genetics and Metabolism. 105(4):629-633

"Protein kinase A regulatory subunit isoforms regulate growth and differentiation in Mucor circinelloides: Essential role of pkaR4" (2012) Ocampo, J.;McCormack, B.;Navarro, E. (...)Rossi, S. Eukaryotic Cell. 11(8):989-1002

"PKA isoforms coordinate mRNA fate during nutrient starvation" (2012) Tudisca, V.;Simpson, C.;Castelli, L. (...)Portela, P. Journal of Cell Science. 125(21):5221-5232

"Staufen: From embryo polarity to cellular stress and neurodegeneration" (2012) Tosar, L.J.M.;Thomas, M.G.;Baez, M.V. (...)Boccaccio, G.L. Frontiers in Bioscience - Scholar. 4 S(2):432-452

"Structure-based analysis of five novel disease-causing mutations in 21-hydroxylase-deficient patients" (2011) Minutolo, C.;Nadra, A.D.;Fernández, C. (...)Dain, L. PLoS ONE. 6(1)

"Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain" (2011) Devries, I.; Ferreiro, D.U.; Sánchez, I.E.; Komives, E.A. Journal of Molecular Biology. 408(1):163-176

"Genetic mapping of EST-SSRs, SSR and InDels to improve saturation of genomic regions in a previously developed sunflower map" (2010) Talia, P.;Nishinakamasu, V.;Hopp, H.E. (...)Paniego, N. Electronic Journal of Biotechnology. 13(6)

"Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast" (2010) Bodenmiller, B.;Wanka, S.;Kraft, C. (...)Aebersold, R. Science Signaling. 3(153)

"17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions" (2010) Gambino, Y.P.;Maymó, J.L.;Pérez-Pérez, A. (...)Varone, C.L. Biology of Reproduction. 83(1):42-51

"Differential localization to cytoplasm, nucleus or P-bodies of yeast PKA subunits under different growth conditions" (2010) Tudisca, V.;Recouvreux, V.;Moreno, S. (...)Portela, P. European Journal of Cell Biology. 89(4):339-348

"Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions" (2009) Nikel, P.I.;Zhu, J.;San, K.-Y. (...)Bennett, G.N. Journal of Bacteriology. 191(17):5538-5548

"Role of pre-A motif in nitric oxide scavenging by truncated hemoglobin, HbN, of Mycobacterium tuberculosis" (2009) Lama, A.;Pawaria, S.;Bidon-Chanal, A. (...)Dikshit, K.L. Journal of Biological Chemistry. 284(21):14457-14468

"Interplay between two RND systems mediating antimicrobial resistance in brucella suis" (2009) Martin, F.A.;Posadas, D.M.;Carrica, M.C. (...)Zorreguieta, A. Journal of Bacteriology. 191(8):2530-2540

"Escherichia coli arcA mutants: Metabolic profile characterization of microaerobic cultures using glycerol as a carbon source" (2008) Nikel, P.I.;Pettinari, M.J.;Ramírez, M.C. (...)Méndez, B.S. Journal of Molecular Microbiology and Biotechnology. 15(1):48-54

"Genetic and biochemical studies in Argentinean patients with variegate porphyria" (2008) Rossetti, M.V.;Granata, B.X.;Giudice, J. (...)Batlle, A. BMC Medical Genetics. 9

"Multiple pathways for triacylglycerol biosynthesis in Streptomyces coelicolor" (2008) Arabolaza, A.;Rodriguez, E.;Altabe, S. (...)Gramajo, H. Applied and Environmental Microbiology. 74(9):2573-2582

"Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons" (2008) Guo, C.;Qiu, H.-Y.;Shi, M. (...)Ding, Y.-Q. Journal of Neuroscience. 28(52):14097-14106

"The legacy of HfrH: Mutations in the two-component system CreBC are responsible for the unusual phenotype of an Escherichia coli arcA mutant" (2008) Nikel, P.I.; De Almeida, A.; Pettinari, M.J.; Méndez, B.S. Journal of Bacteriology. 190(9):3404-3407

"New insights into the regulation of the Saccharomyces cerevisiae UGA54 gene: Two parallel pathways participate in carbon-regulated transcription" (2007) Luzzani, C.; Cardillo, S.B.; Moretti, M.B.; García, S.C. Microbiology. 153(11):3677-3684

"Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence" (2007) Bumaschny, V.F.;De Souza, F.S.J.;Leal, R.A.L. (...)Rubinstein, M. Molecular Endocrinology. 21(11):2738-2749

"RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20" (2006) De La Mata, M.; Kornblihtt, A.R. Nature Structural and Molecular Biology. 13(11):973-980

"Effects of N-starvation and C-source on Bradyrhizobium japonicum exopolysaccharide production and composition, and bacterial infectivity to soybean roots" (2006) Quelas, J.I.;López-García, S.L.;Casabuono, A. (...)Lodeiro, A.R. Archives of Microbiology. 186(2):119-128

"Hereditary neuropathy with liability to pressure palsies manifesting by recurrent neuropathic pain" (2006) Barroso, F.A.; Leiguarda, R.; Nogués, M.A. Journal of Clinical Neuromuscular Disease. 8(1):26-30

"Poly(3-hydroxybutyrate) synthesis by recombinant Escherichia coli arcA mutants in microaerobiosis" (2006) Nikel, P.I.; Pettinari, M.J.; Galvagno, M.A.; Méndez, B.S. Applied and Environmental Microbiology. 72(4):2614-2620

"Xanthan induces plant susceptibility by suppressing callose deposition" (2006) Yun, M.H.;Torres, P.S.;El Oirdi, M. (...)Vojnov, A.A. Plant Physiology. 141(1):178-187

"Prevalence of GJB2 mutations and the del(GJB6-D13S1830) in Argentinean non-syndromic deaf patients" (2005) Dalamón, V.;Béhèran, A.;Diamante, F. (...)Elgoyhen, A.B. Hearing Research. 207(1-2):43-49

"Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting" (2005) De Souza, F.S.J.;Santangelo, A.M.;Bumaschny, V. (...)Rubinstein, M. Molecular and Cellular Biology. 25(8):3076-3086

"Hepatic nuclear factor 3 and nuclear factor 1 regulate 5-aminolevulinate synthase gene expression and are involved in insulin repression" (2004) Scassa, M.E.; Guberman, A.S.; Ceruti, J.M.; Cánepa, E.T. Journal of Biological Chemistry. 279(27):28082-28092

"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746

"Inhibitory effect of AP-1 complex on 5-aminolevulinate synthase gene expression through sequestration of cAMP-response element protein (CRE)-binding protein (CBP) coactivator" (2003) Guberman, A.S.;Scassa, M.E.;Giono, L.E. (...)Cánepa, E.T. Journal of Biological Chemistry. 278(4):2317-2326

"Finding Unexpected Patterns in Microarray Data" (2003) Perelman, S.;Mazzella, M.A.;Muschietti, J. (...)Casal, J.J. Plant Physiology. 133(4):1717-1725

"Thrittene, homologous with somatostatin-28(1-13), is a novel peptide in mammalian gut and circulation" (2002) Ensinck, J.W.;Baskin, D.G.;Vahl, T.P. (...)D'Alessio, D.A. Endocrinology. 143(7):2599-2609

"5-aminolaevulinate synthase gene promoter contains two cAMP-response element (CRE)-like sites that confer positive and negative responsiveness to CRE-binding protein (CREB)" (2001) Giono, L.E.; Varone, C.L.; Cánepa, E.T. Biochemical Journal. 353(2):307-316

"Evaluation of in vivo activation of protein kinase A under non-dissociable conditions through the overexpression of wild-type and mutant regulatory subunits in Saccharomyces cerevisiae" (2001) Portela, P.; Zaremberg, V.; Moreno, S. Microbiology. 147(5):1149-1159

"Poly(3-Hydroxybutyrate) Synthesis Genes in Azotobacter sp. Strain FA8" (2001) Pettinari, M.J.;Vázquez, G.J.;Silberschmidt, D. (...)Méndez, B.S. Applied and Environmental Microbiology. 67(3-12):5331-5334

"Recurrent amplifications and deletions of satellite DNA accompanied chromosomal diversification in South American tuco-tucos (genus Ctenomys, Rodentia: Octodontidae): A phylogenetic approach" (2001) Slamovits, C.H.; Cook, J.A.; Lessa, E.P.; Rossi, M.S. Molecular Biology and Evolution. 18(9):1708-1719

"Identification and characterization of two novel mutations that produce acute intermittent porphyria: A 3-base deletion (841-843delGGA) and a missense mutation (T35M)." (2000) De Siervi, A.;Weiss Cádiz, D.E.;Parera, V.E. (...)Rossetti, M.V. Human mutation. 16(4):373

"Authentic cell-specific and developmentally regulated expression of pro- opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice" (1998) Young, J.I.;Otero, V.;Cerdán, M.G. (...)Rubinstein, M. Journal of Neuroscience. 18(17):6631-6640

"Interaction of the -170 cyclic AMP response element with the adjacent CCAAT box in the human fibronectin gene promoter" (1992) Muro, A.F.; Bernath, V.A.; Kornblihtt, A.R. Journal of Biological Chemistry. 267(18):12767-12774