Lista de

knockout mouse
49
"Dendritic Cells Exposed to Triiodothyronine Deliver Pro-Inflammatory Signals and Amplify IL-17-Driven Immune Responses" (2019) Alamino, V.A.;Montesinos, M.D.M.;Soler, M.F. (...)Pellizas, C.G. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 52(2):354-367
"Positive regulation of raphe serotonin neurons by serotonin 2B receptors" (2018) Belmer, A.;Quentin, E.;Diaz, S.L. (...)Maroteaux, L. Neuropsychopharmacology. 43(7):1623-1632
"Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk" (2018) Orozco, C.A.;Martinez-Bosch, N.;Guerrero, P.E. (...)Navarro, P. Proceedings of the National Academy of Sciences of the United States of America. 115(16):E3769-E3778
"Inducible ablation of dopamine D2 receptors in adult mice impairs locomotion, motor skill learning and leads to severe parkinsonism" (2017) Bello, E.P.;Casas-Cordero, R.;Galiñanes, G.L. (...)Rubinstein, M. Molecular Psychiatry. 22(4):595-604
"Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery" (2017) Clemente, T.;Vieira, N.J.;Cerliani, J.P. (...)Amarante-Mendes, G.P. Cell death & disease. 8(12):e3176
"Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase" (2017) Giono, L.E.;Resnick-Silverman, L.;Carvajal, L.A. (...)Manfredi, J.J. Oncogene. 36(49):6762-6773
"The Role of Heterotypic DENV-specific CD8+ T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection" (2017) Talarico, L.B.;Batalle, J.P.;Byrne, A.B. (...)Polack, F.P. EBioMedicine. 20:202-216
"Modulation of GABA release from the thalamic reticular nucleus by cocaine and caffeine: Role of serotonin receptors" (2016) Goitia, B.;Rivero-Echeto, M.C.;Weisstaub, N.V. (...)Urbano, F.J. Journal of Neurochemistry. 136(3):526-535
"Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine d2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance" (2016) Luque, G.M.;Lopez-Vicchi, F.;María Ornstein, A. (...)Becu-Villalobos, D. American Journal of Physiology - Endocrinology and Metabolism. 311(6):E974-E988
"Hypothalamic POMC deficiency improves glucose tolerance despite insulin resistance by increasing Glycosuria" (2016) Chhabra, K.H.;Adams, J.M.;Fagel, B. (...)Low, M.J. Diabetes. 65(3):660-672
"Essential function of the transcription factor Rax in the early patterning of the mammalian hypothalamus" (2016) Orquera, D.P.;Nasif, S.;Low, M.J. (...)de Souza, F.S.J. Developmental Biology. 416(1):212-224
"Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of Cocaine" (2016) Dobbs, L.K.;Kaplan, A.R.;Lemos, J.C. (...)Alvarez, V.A. Neuron. 90(5):1100-1113
"Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: Implications for fertility disorders" (2016) Brukman, N.G.;Miyata, H.;Torres, P. (...)Cuasnicú, P.S. Molecular Human Reproduction. 22(4):240-251
"Trypanosoma cruzi infection imparts a regulatory program in dendritic cells and T cells via galectin-1-dependent mechanisms" (2015) Poncini, C.V.;Ilarregui, J.M.;Batalla, E.I. (...)Rabinovich, G.A. Journal of Immunology. 195(7):3311-3324
"Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood" (2015) Nasif, S.;De Souza, F.S.J.;González, L.E. (...)Rubinstein, M. Proceedings of the National Academy of Sciences of the United States of America. 112(15):E1861-E1870
"The galectin-1-glycan axis controls sperm fertilizing capacity by regulating sperm motility and membrane hyperpolarization" (2015) Vasen, G.;Battistone, M.A.;Croci, D.O. (...)Cuasnicú, P.S. FASEB Journal. 29(10):4189-4200
"Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology" (2015) Pérez, C.V.;Gómez, L.G.;Gualdoni, G.S. (...)Guazzone, V.A. Scientific Reports. 5
"Loss of Feedback Inhibition via D2 Autoreceptors Enhances Acquisition of Cocaine Taking and Reactivity to Drug-Paired Cues" (2015) Holroyd, K.B.;Adrover, M.F.;Fuino, R.L. (...)Alvarez, V.A. Neuropsychopharmacology. 40(6):1495-1509
"Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells" (2015) Benatar, A.F.;García, G.A.;Bua, J. (...)Gómez, K.A. PLoS Neglected Tropical Diseases. 9(10)
"NF-κB transcription factor role in consolidation and reconsolidation of persistent memories" (2015) de la Fuente, V.;Federman, N.;Zalcman, G. (...)Romano, A. Frontiers in Molecular Neuroscience. 8(September)
"H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway" (2014) Eberhardt, M.;Dux, M.;Namer, B. (...)Filipovic, M.R. Nature Communications. 5
"Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses" (2013) Johnson, S.L.;Wedemeyer, C.;Vetter, D.E. (...)Marcotti, W. Open Biology. 3(NOV)
"Hippocampal SPARC regulates depression-related behavior" (2012) Campolongo, M.;Benedetti, L.;Podhajcer, O.L. (...)Depino, A.M. Genes, Brain and Behavior. 11(8):966-976
"Hippocampal SPARC regulates depression-related behavior" (2012) Campolongo, M.;Benedetti, L.;Podhajcer, O.L. (...)Depino, A.M. Genes, Brain and Behavior. 11(8):966-976
"Neurotransmitter modulation of the GHRH-GH axis" (2010) García-Tornadu, I.;Risso, G.;Perez-Millan, M.I. (...)Guitelman M. Frontiers of Hormone Research. 38:59-69
"Hypothalamic orexin, OX1, αMSH, NPY and MCRs expression in dopaminergic D2R knockout mice" (2009) García-Tornadú, I.;Díaz-Torga, G.;Risso, G.S. (...)Becu-Villalobos, D. Neuropeptides. 43(4):267-274
"P/Q Ca2+ channels are functionally coupled to exocytosis of the immediately releasable pool in mouse chromaffin cells" (2008) Álvarez, Y.D.; Ibañez, L.I.; Uchitel, O.D.; Marengo, F.D. Cell Calcium. 43(2):155-164
"Fibroblast growth factor-2 in hyperplastic pituitaries of D2R knockout female mice" (2007) Cristina, C.;Díaz-Torga, G.;Góngora, A. (...)Becu-Villalobos, D. American Journal of Physiology - Endocrinology and Metabolism. 293(5):E1341-E1351
"GH in the dwarf dopaminergic D2 receptor knockout mouse: Somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin" (2006) García-Tornadú, I.;Rubinstein, M.;Gaylinn, B.D. (...)Becu-Villalobos, D. Journal of Endocrinology. 190(3):611-619
"Genetically modified mouse models in studies of luteinising hormone action" (2006) Huhtaniemi, I.;Ahtiainen, P.;Pakarainen, T. (...)Poutanen, M. Molecular and Cellular Endocrinology. 252(1-2):126-135
"Evolutionarily-conserved role of the NF-κB transcription factor in neural plasticity and memory" (2006) Romano, A.; Freudenthal, R.; Merlo, E.; Routtenberg, A. European Journal of Neuroscience. 24(6):1507-1516
"Increased pituitary vascular endothelial growth factor-A in dopaminergic D2 receptor knockout female mice" (2005) Cristina, C.;Díaz-Torga, G.;Baldi, A. (...)Becú-Villalobos, D. Endocrinology. 146(7):2952-2962
"Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle" (2005) García-Rivello, H.;Taranda, J.;Said, M. (...)Hertig, C.M. American Journal of Physiology - Heart and Circulatory Physiology. 289(3 58-3):H1153-H1160
"Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas" (2005) Refojo, D.;Echenique, C.;Müller, M.B. (...)Arzt, E. Proceedings of the National Academy of Sciences of the United States of America. 102(17):6183-6188
"Functional compensation of P/Q by N-type channels blocks short-term plasticity at the calyx of Held presynaptic terminal" (2004) González Inchauspe, C.; Martini, F.J.; Forsythe, I.D.; Uchitel, O.D. Journal of Neuroscience. 24(46):10379-10383
"State-dependent modulation of feeding behavior by proopiomelanocortin-derived β-endorphin" (2003) Low, M.J.; Hayward, M.D.; Appleyard, S.M.; Rubinstein, M. Annals of the New York Academy of Sciences. 994:192-201
"Ca2+ channels and synaptic transmission at the adult, neonatal, and P/Q-type deficient neuromuscular junction" (2003) Nudler, S.;Piriz, J.;Urbano, F.J. (...)Uchitel, O.D. Annals of the New York Academy of Sciences. 998:11-17
"Calcium channels involved in neurotransmitter release at adult, neonatal and P/Q-type deficient neuromuscular junctions (review)" (2002) Urbano, F.J.; Rosato-Siri, M.D.; Uchitel, O.D. Molecular Membrane Biology. 19(4):293-300
"Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice" (2002) Díaz-Torga, G.;Feierstein, C.;Libertun, C. (...)Becú-Villalobos, D. Endocrinology. 143(4):1270-1279
"Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors" (2002) Nir, I.;Harrison, J.M.;Haque, R. (...)Iuvone, P.M. Journal of Neuroscience. 22(6):2063-2073
"Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice" (2002) Chausmer, A.L.;Elmer, G.I.;Rubinstein, M. (...)Katz, J.L. Psychopharmacology. 163(1):54-61
"The role of the D2 dopamine receptor (D2R) in A2A adenosine receptor (A2AR)-mediated behavioral and cellular responses as revealed by A2A and D2 receptor knockout mice" (2001) Chen, J.-F.;Moratalla, R.;Impagnatiello, F. (...)Schwarzschild, M.A. Proceedings of the National Academy of Sciences of the United States of America. 98(4):1970-1975
"The dopamine D 2 , but not D 3 or D 4 , receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice" (1999) Ralph, R.J.;Varty, G.B.;Kelly, M.A. (...)Geyer, M.A. Journal of Neuroscience. 19(11):4627-4633
"Role of α9 nicotinic ACh receptor subunits in the development and function of cochlear efferent innervation" (1999) Vetter, D.E.;Liberman, M.C.;Mann, J. (...)Elgoyhen, A.B. Neuron. 23(1):93-103