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antiproliferative activity
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"Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents" (2019) Chanquia, S.N.;Larregui, F.;Puente, V. (...)García Liñares, G. Bioorganic Chemistry. 83:526-534
"New insights in cushing disease treatment with focus on a derivative of vitamin A" (2018) Fuertes, M.;Tkatch, J.;Rosmino, J. (...)Arzt, E. Frontiers in Endocrinology. 9(MAY)
"Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis article" (2018) Gueron, G.;Anselmino, N.;Chiarella, P. (...)Vazquez, E. Cell Death and Disease. 9(2)
"Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl D-ribofuranosides" (2017) Avanzo, R.E.; Padrón, J.M.; D'Accorso, N.B.; Fascio, M.L. Bioorganic and Medicinal Chemistry Letters. 27(16):3674-3677
"Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl D-ribofuranosides" (2017) Avanzo, R.E.; Padrón, J.M.; D'Accorso, N.B.; Fascio, M.L. Bioorganic and Medicinal Chemistry Letters. 27(16):3674-3677
"Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model" (2017) Marostica, L.L.;de Barros, A.L.B.;Oliveira, J. (...)Simões, C.M.O. Toxicology and Applied Pharmacology. 329:272-281
"Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling" (2016) Sampson, J.F.;Suryawanshi, A.;Chen, W.-S. (...)Panjwani, N. Immunology and Cell Biology. 94(2):213-219
"Heteromerization between the Bradykinin B2 Receptor and the Angiotensin-(1-7) Mas Receptor: Functional Consequences" (2016) Cerrato, B.D.;Carretero, O.A.;Janic, B. (...)Gironacci, M.M. Hypertension. 68(4):1039-1048
"Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties" (2015) Fascio, M.L.; Errea, M.I.; D'Accorso, N.B. European Journal of Medicinal Chemistry. 90:666-683
"Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549" (2015) Marostica, L.L.;Silva, I.T.;Kratz, J.M. (...)Simões, C.M.O. Chemical Research in Toxicology. 28(10):1949-1960
"Polyoxygenated steroids from the octocoral leptogorgia punicea and in vitro evaluation of their cytotoxic activity" (2014) Moritz, M.I.G.;Marostica, L.L.;Bianco, É.M. (...)Schenkel, E.P. Marine Drugs. 12(12):5864-5880
"Synthesis and biological evaluation of salpichrolide analogs as antiestrogenic agents" (2014) Sonego, J.M.;Rivero, E.M.;Gargiulo, L. (...)Burton, G. European Journal of Medicinal Chemistry. 82:233-241
"Synthesis and biological evaluation of salpichrolide analogs as antiestrogenic agents" (2014) Sonego, J.M.;Rivero, E.M.;Gargiulo, L. (...)Burton, G. European Journal of Medicinal Chemistry. 82:233-241
"Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line" (2014) Lang, K.L.;Silva, I.T.;Machado, V.R. (...)De Melo, E.B. Journal of Molecular Graphics and Modelling. 48:70-79
"QSAR on antiproliferative naphthoquinones based on a conformation- independent approach" (2014) Duchowicz, P.R.;Bennardi, D.O.;Bacelo, D.E. (...)Misico, R.I. European Journal of Medicinal Chemistry. 77:176-184
"Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines" (2014) Cardama, G.A.;Comin, M.J.;Hornos, L. (...)Menna, P.L. Anti-Cancer Agents in Medicinal Chemistry. 14(6):840-851
"Pseudocnoside A, a new cytotoxic and antiproliferative triterpene glycoside from the sea cucumber Pseudocnus dubiosus leoninus" (2014) Careaga, V.P.;Bueno, C.;Muniain, C. (...)Maier, M.S. Natural Product Research. 28(4):213-220
"Agarofuran sesquiterpenes from Schaefferia argentinensis" (2013) García, M.E.;Motrich, R.D.;Caputto, B.L. (...)Nicotra, V.E. Phytochemistry. 94:260-267
"Agarofuran sesquiterpenes from Schaefferia argentinensis" (2013) García, M.E.;Motrich, R.D.;Caputto, B.L. (...)Nicotra, V.E. Phytochemistry. 94:260-267
"Agarofuran sesquiterpenes from Schaefferia argentinensis" (2013) García, M.E.;Motrich, R.D.;Caputto, B.L. (...)Nicotra, V.E. Phytochemistry. 94:260-267
"Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2" (2013) Guillon, J.;Le Borgne, M.;Rimbault, C. (...)Jose, J. European Journal of Medicinal Chemistry. 65:205-222
"Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2" (2013) Guillon, J.;Le Borgne, M.;Rimbault, C. (...)Jose, J. European Journal of Medicinal Chemistry. 65:205-222
"Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn" (2013) Silva, I.T.;Teixeira, C.R.;Lang, K.L. (...)Simões, C.M.O. International Journal of Cancer Research. 9(2):54-68
"Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas" (2013) Curic, S.;Wu, Y.;Shan, B. (...)Renner, U. Journal of Neuro-Oncology. 113(3):385-396
"Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents" (2013) Elicio, P.D.;Chao, M.N.;Galizzi, M. (...)Rodriguez, J.B. European Journal of Medicinal Chemistry. 69:480-489
"β-Lapachone analogs with enhanced antiproliferative activity" (2012) Ríos-Luci, C.;Bonifazi, E.L.;León, L.G. (...)Padrón, J.M. European Journal of Medicinal Chemistry. 53:264-274
"A natural antiviral and immunomodulatory compound with antiangiogenic properties" (2012) Bueno, C.A.; Lombardi, M.G.; Sales, M.E.; Alché, L.E. Microvascular Research. 84(3):235-241
"New antibacterials for the treatment of toxoplasmosis; A patent review" (2012) Rodriguez, J.B.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 22(3):311-333
"1,2,4-Triazole d-ribose derivatives: Design, synthesis and antitumoral evaluation" (2012) Avanzo, R.E.;Anesini, C.;Fascio, M.L. (...)D'Accorso, N.B. European Journal of Medicinal Chemistry. 47(1):104-110