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García, M.E.; Motrich, R.D.; Caputto, B.L.; Sánchez, M.; Palermo, J.A.; Estévez-Braun, A.; Ravelo, A.G.; Nicotra, V.E. "Agarofuran sesquiterpenes from Schaefferia argentinensis" (2013) Phytochemistry. 94:260-267
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Abstract:

Sixteen dihydro-β-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and MDA-MB231 human cancer cell lines, but was found to be marginal. © 2013 Elsevier Ltd. All rights reserved.

Registro:

Documento: Artículo
Título:Agarofuran sesquiterpenes from Schaefferia argentinensis
Autor:García, M.E.; Motrich, R.D.; Caputto, B.L.; Sánchez, M.; Palermo, J.A.; Estévez-Braun, A.; Ravelo, A.G.; Nicotra, V.E.
Filiación:Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Universidad Nacional de Córdoba, 5000 Córdoba, Argentina
Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC-CONICET), Universidad Nacional de Córdoba, 5000 Córdoba, Argentina
Unidad de Microanalisis y Metodos Fisicos Aplicados A la Quimica Organica, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina
Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG), Universidad de la Laguna, 38206 La Laguna, Spain
Palabras clave:Antiproliferative activity; Celastraceae; Dihydro-β-agarofuran sesquiterpene; Phytochemistry; Schaefferia argentinensis; Celastraceae; Schaefferia (angiosperm); antineoplastic agent; dihydroagarofuran; sesquiterpene; antiproliferative activity; article; Celastraceae; cell proliferation; cell strain MCF 7; cell survival; chemical structure; chemistry; Dihydro-β-agarofuran sesquiterpene; drug effect; human; isolation and purification; mass spectrometry; methodology; nuclear magnetic resonance spectroscopy; phytochemistry; plant; Schaefferia argentinensis; tumor cell line; Antiproliferative activity; Celastraceae; Dihydro-β-agarofuran sesquiterpene; Phytochemistry; Schaefferia argentinensis; Antineoplastic Agents, Phytogenic; Celastraceae; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; MCF-7 Cells; Molecular Structure; Plant Components, Aerial; Sesquiterpenes
Año:2013
Volumen:94
Página de inicio:260
Página de fin:267
DOI: http://dx.doi.org/10.1016/j.phytochem.2013.06.003
Título revista:Phytochemistry
Título revista abreviado:Phytochemistry
ISSN:00319422
CODEN:PYTCA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v94_n_p260_Garcia

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Citas:

---------- APA ----------
García, M.E., Motrich, R.D., Caputto, B.L., Sánchez, M., Palermo, J.A., Estévez-Braun, A., Ravelo, A.G.,..., Nicotra, V.E. (2013) . Agarofuran sesquiterpenes from Schaefferia argentinensis. Phytochemistry, 94, 260-267.
http://dx.doi.org/10.1016/j.phytochem.2013.06.003
---------- CHICAGO ----------
García, M.E., Motrich, R.D., Caputto, B.L., Sánchez, M., Palermo, J.A., Estévez-Braun, A., et al. "Agarofuran sesquiterpenes from Schaefferia argentinensis" . Phytochemistry 94 (2013) : 260-267.
http://dx.doi.org/10.1016/j.phytochem.2013.06.003
---------- MLA ----------
García, M.E., Motrich, R.D., Caputto, B.L., Sánchez, M., Palermo, J.A., Estévez-Braun, A., et al. "Agarofuran sesquiterpenes from Schaefferia argentinensis" . Phytochemistry, vol. 94, 2013, pp. 260-267.
http://dx.doi.org/10.1016/j.phytochem.2013.06.003
---------- VANCOUVER ----------
García, M.E., Motrich, R.D., Caputto, B.L., Sánchez, M., Palermo, J.A., Estévez-Braun, A., et al. Agarofuran sesquiterpenes from Schaefferia argentinensis. Phytochemistry. 2013;94:260-267.
http://dx.doi.org/10.1016/j.phytochem.2013.06.003