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enzyme mechanism

"Structural and mechanistic comparison of the Cyclopropane Mycolic Acid Synthases (CMAS) protein family of Mycobacterium tuberculosis" (2018) Defelipe, L.A.; Osman, F.; Marti, M.A.; Turjanski, A.G. Biochemical and Biophysical Research Communications. 498(2):288-295

"Multiscale approach to the activation and phosphotransfer mechanism of CpxA histidine kinase reveals a tight coupling between conformational and chemical steps" (2018) Marsico, F.;Burastero, O.;Defelipe, L.A. (...)Marti, M.A. Biochemical and Biophysical Research Communications. 498(2):305-312

"Lipase-catalyzed acetylation and esterification of bile acids" (2018) Baldessari, A.; García Liñares, G. Methods in Molecular Biology. 1835:337-350

"Kinetics, subcellular localization, and contribution to parasite virulence of a Trypanosoma cruzi hybrid type A heme peroxidase (TcAPx-CcP)" (2017) Hugo, M.;Martínez, A.;Trujillo, M. (...)Radi, R. Proceedings of the National Academy of Sciences of the United States of America. 114(8):E1326-E1335

"An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method" (2017) Lara-Ramirez, E.E.;López-Cedillo, J.C.;Nogueda-Torres, B. (...)Rivera, G. European Journal of Medicinal Chemistry. 132:249-261

"First whole-genome shotgun sequence of a promising cellulase secretor, Trichoderma koningiopsis strain POS7" (2017) Castrillo, M.L.;Bich, G.A.;Modenutti, C. (...)Villalba, L.L. Genome Announcements. 5(37)

"Structural and functional characterization of a cold-adapted stand-alone TPM domain reveals a relationship between dynamics and phosphatase activity" (2016) Pellizza, L.A.;Smal, C.;Ithuralde, R.E. (...)Arán, M. FEBS Journal. 283(23):4370-4385

"Steered Molecular Dynamics Methods Applied to Enzyme Mechanism and Energetics" (2016) Ramírez, C.L.; Martí, M.A.; Roitberg, A.E. Methods in Enzymology. 578:123-143

"Revisiting direct electron transfer in nanostructured carbon laccase oxygen cathodes" (2016) Adam, C.;Scodeller, P.;Grattieri, M. (...)Calvo, E.J. Bioelectrochemistry. 109:101-107

"Circannual rhythms of acetylcholinesterase (AChE) activity in the freshwater fish Cnesterodon decemmaculatus" (2015) Menéndez-Helman, R.J.; Ferreyroa, G.V.; dos Santos Afonso, M.; Salibián, A. Ecotoxicology and Environmental Safety. 111:236-241

"Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi" (2015) García Liñares, G.;Antonela Zígolo, M.;Simonetti, L. (...)Baldessari, A. Bioorganic and Medicinal Chemistry. 23(15):4804-4814

"Association of HO-1 and BRCA1 is critical for the maintenance of cellular homeostasis in prostate cancer" (2015) Labanca, E.;De Luca, P.;Gueron, G. (...)De Siervi, A. Molecular Cancer Research. 13(11):1455-1464

"Alternative cycling modes of the Na+/K+-ATPase in the presence of either Na+ or Rb+" (2013) Monti, J.L.E.; Montes, M.R.; Rossi, R.C. Biochimica et Biophysica Acta - Biomembranes. 1828(5):1374-1383

"Biocatalytic synthesis of chiral N-(2-hydroxyalkyl)-acrylamides" (2011) Monsalve, L.N.; Rustoy, E.M.; Baldessari, A. Biocatalysis and Biotransformation. 29(2-3):87-95

"Enzymatic regioselective and complete deacetylation of two arabinonucleosides" (2010) Sabaini, M.B.;Zinni, M.A.;Mohorčič, M. (...)Iglesias, L.E. Journal of Molecular Catalysis B: Enzymatic. 62(3-4):225-229

"Synthesis of PEGylated lactose analogs for inhibition studies on T.cruzi trans-sialidase" (2010) Giorgi, M.E.;Ratier, L.;Agusti, R. (...)De Lederkremer, R.M. Glycoconjugate Journal. 27(5):549-559

"Evidence for a ferryl intermediate in a heme-based dioxygenase" (2009) Lewis-Ballester, A.;Batabyal, D.;Egawa, T. (...)Yeh, S.-R. Proceedings of the National Academy of Sciences of the United States of America. 106(41):17371-17376

"Diastereoselective enzymatic preparation of acetylated pentofuranosides carrying free 5-hydroxyl groups" (2009) Gudiño, E.D.; Iribarren, A.M.; Iglesias, L.E. Tetrahedron Asymmetry. 20(15):1813-1816

"Cruzipain, the major cysteine protease of Trypanosoma cruzi: A sulfated glycoprotein antigen as relevant candidate for vaccine development and drug target. A review" (2009) Duschak, V.G.; Couto, A.S. Current Medicinal Chemistry. 16(24):3174-3202

"Extracting kinetic parameters for homogeneous [Os(bpy)2ClPyCOOH]+ mediated enzyme reactions from cyclic voltammetry and simulations" (2008) Flexer, V.; Ielmini, M.V.; Calvo, E.J.; Bartlett, P.N. Bioelectrochemistry. 74(1):201-209

"Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose" (2007) Agustí, R.;Giorgi, M.E.;Mendoza, V.M. (...)de Lederkremer, R.M. Bioorganic and Medicinal Chemistry. 15(7):2611-2616

"Turing patterns inside cells" (2007) Strier, D.E.; Dawson, S.P. PLoS ONE. 2(10)

"Deacetylation of furanosides using banana as biocatalyst" (2007) Taverna-Porro, M.; Iglesias, L.E.; Montserrat, J.M.; Iribarren, A.M. Journal of Molecular Catalysis B: Enzymatic. 44(3-4):138-143

"Nucleoside phosphorylases" (2006) Lewkowicz, E.S.; Iribarren, A.M. Current Organic Chemistry. 10(11):1197-1215

"Abnormal kinetic behavior of uroporphyrinogen decarboxylase obtained from rats with hexachlorobenzene-induced porphyria" (2005) Chaufan, G.;Corvi, M.M.;San Martín De Viale, L.C. (...)Ríos De Molina, M.D.C. Journal of Biochemical and Molecular Toxicology. 19(1):19-24

"Deprotection of peracetylated methyl D-ribosides through enzymatic alcoholysis: Different recognition of the anomers" (2005) Iñigo, S.;Porro, M.T.;Montserrat, J.M. (...)Iribarren, A.M. Journal of Molecular Catalysis B: Enzymatic. 35(1-3):70-73

"The action of the mast cell product tryptase on cyclooxygenase-2 (COX2) and subsequent fibroblast proliferation involves activation of the extracellular signal-regulated kinase isoforms 1 and 2 (erk1/2)" (2005) Frungieri, M.B.; Albrecht, M.; Raemsch, R.; Mayerhofer, A. Cellular Signalling. 17(4):525-533

"A high-throughput screening for phosphatases using specific substrates" (2005) Senn, A.M.; Wolosiuk, R.A. Analytical Biochemistry. 339(1):150-156

"Combination strategy using pure enzymes and whole cells as biocatalysts for the preparation of 2-hydroxyesters and lactones from 2-oxoglutaric acid" (2004) Rustoy, E.M.; Pereyra, E.N.; Moreno, S.; Baldessari, A. Tetrahedron Asymmetry. 15(23):3763-3768

"Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: A simple model for kinetic interpretation of mechanism-based inhibitors" (2001) Matkovic, L.; Gomez-Sanchez, C.E.; Cozza, E.N. Journal of Biochemistry. 129(3):383-390

"Histamine H2 receptor desensitization: Involvement of a select array of G protein-coupled receptor kinases" (2001) Shayo, C.;Fernandez, N.;Legnazzi, B.L. (...)Davio, C. Molecular Pharmacology. 60(5):1049-1056

"Complete and regioselective deacetylation of peracetylated uridines using a lipase" (2000) Iglesias, L.E.; Zinni, M.A.; Gallo, M.; Iribarren, A.M. Biotechnology Letters. 22(5):361-365

"Lipase-catalyzed polymerization of glycerol and dicarboxylic acids in an organic medium" (2000) Pessagno, R.C.; Baldessari, A. Molecules. 5(3):372-373

"Corticosteroid synthesis in the central nervous system" (1996) Gomez-Sanchez, C.E.;Zhou, M.Y.;Cozza, E.N. (...)Gomez-Sanchez, E.P. Endocrine Research. 22(4):463-470

"Kinetic studies on the glutamate:glyoxylate transaminase of Euglena gracilis" (1996) Lombardo, M.E.; Araujo, L.S.; Del C. Batlle, A.M. Journal of Photochemistry and Photobiology B: Biology. 36(3):241-244

"Enhancement of the reductive activation of chloroplast fructose‐1,6‐bisphosphatase by modulators and protein perturbants" (1994) Ballicora, M.A.; Wolosiuk, R.A. European Journal of Biochemistry. 222(2):467-474

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