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enhancer region
20
"Comprehensive Analysis of a cis-Regulatory Region Reveals Pleiotropy in Enhancer Function" (2018) Preger-Ben Noon, E.;Sabarís, G.;Ortiz, D.M. (...)Frankel, N. Cell Reports. 22(11):3021-3031
"The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription" (2018) Mikhaylichenko, O.;Bondarenko, V.;Harnett, D. (...)Furlong, E.E.M. Genes and Development. 32(1):42-57
"Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood" (2015) Nasif, S.;De Souza, F.S.J.;González, L.E. (...)Rubinstein, M. Proceedings of the National Academy of Sciences of the United States of America. 112(15):E1861-E1870
"Low affinity binding site clusters confer HOX specificity and regulatory robustness" (2015) Crocker, J.;Abe, N.;Rinaldi, L. (...)Stern, D.L. Cell. 160(1-2):191-203
"Low affinity binding site clusters confer HOX specificity and regulatory robustness" (2015) Crocker, J.;Abe, N.;Rinaldi, L. (...)Stern, D.L. Cell. 160(1-2):191-203
"Long range chromatin organization: A new layer in splicing regulation?" (2014) Gómez Acuña, L.I.; Kornblihtt, A.R. Transcription. 5(APR):e28726-1-e28726-5
"Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants" (2014) Pasquali, L.;Gaulton, K.J.;Rodríguez-Seguí, S.A. (...)Ferrer, J. Nature Genetics. 46(2):136-143
"Enhancer turnover and conserved regulatory function in vertebrate evolution" (2013) Domené, S.;Bumaschny, V.F.;de Souza, F.S.J. (...)Rubinstein, M. Philosophical Transactions of the Royal Society B: Biological Sciences. 368(1632)
"Evolution of transcriptional enhancers and animal diversity" (2013) Rubinstein, M.; de Souza, F.S.J. Philosophical Transactions of the Royal Society B: Biological Sciences. 368(1632)
"Exaptation of transposable elements into novel Cis-regulatory elements: Is the evidence always strong?" (2013) De Souza, F.S.J.; Franchini, L.F.; Rubinstein, M. Molecular Biology and Evolution. 30(6):1239-1251
"A splicing regulator promotes transcriptional elongation" (2008) Fededa, J.P.; Kornblihtt, A.R. Nature Structural and Molecular Biology. 15(8):779-781
"Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene" (2007) Santangelo, A.M.;De Souza, F.S.J.;Franchini, L.F. (...)Rubinstein, M. PLoS Genetics. 3(10):1813-1826
"Steroid Hormones Induce bcl-X Gene Expression through Direct Activation of Distal Promoter P4" (2004) Viegas, L.R.;Vicent, G.P.;Barañao, J.L. (...)Pecci, A. Journal of Biological Chemistry. 279(11):9831-9839
"An early ancestor in the evolution of splicing: A Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing" (2003) Portal, D.;Espinosa, J.M.;Lobo, G.S. (...)Torres, H.N. Molecular and Biochemical Parasitology. 127(1):37-46
"Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation" (2002) Kadener, S.; Fededa, J.P.; Rosbash, M.; Kornblihtt, A.R. Proceedings of the National Academy of Sciences of the United States of America. 99(12):8185-8190
"Transcriptional activators differ in their abilities to control alternative splicing" (2002) Nogués, G.;Kadener, S.;Cramer, P. (...)Kornblihtt, A.R. Journal of Biological Chemistry. 277(45):43110-43114
"Binding of nuclear factors to a satellite DNA of retroviral origin with marked differences in copy number among species of the rodent Ctenomys" (1994) Pesce, C.G.;Rossi, M.S.;Muro, A.F. (...)Kornblihtt, A.R. Nucleic Acids Research. 22(4):656-661