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benznidazole
24
"Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents" (2019) Chanquia, S.N.;Larregui, F.;Puente, V. (...)García Liñares, G. Bioorganic Chemistry. 83:526-534
"Further insights of selenium-containing analogues of WC-9 against Trypanosoma cruzi" (2019) Chao, M.N.;Lorenzo-Ocampo, M.V.;Szajnman, S.H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 27(7):1350-1361
"Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase" (2018) Kashif, M.;Chacón-Vargas, K.F.;López-Cedillo, J.C. (...)Rivera, G. European Journal of Medicinal Chemistry. 156:252-268
"Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi" (2018) Puente, V.;Demaria, A.;Frank, F.M. (...)Lombardo, M.E. PLoS Neglected Tropical Diseases. 12(9)
"Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation" (2017) Chao, M.N.;Storey, M.;Li, C. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 25(24):6435-6449
"Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015)" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 26(9):993-1015
"Chagas disease: The contribution of the center for toxicological research " (2015) Castro, J.A.; De Mecca, M.M.; Gómez, M.I.D.; Castro, G.D. Acta Bioquimica Clinica Latinoamericana. 49(1):73-82
"New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase" (2014) Ferrer-Casal, M.;Li, C.;Galizzi, M. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 22(1):398-405
"Preparation and antitrypanosomal activity of secochiliolide acid derivatives" (2013) Siless, G.E.;Lozano, E.;Sánchez, M. (...)Palermo, J.A. Bioorganic and Medicinal Chemistry Letters. 23(17):4964-4967
"Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents" (2013) Elicio, P.D.;Chao, M.N.;Galizzi, M. (...)Rodriguez, J.B. European Journal of Medicinal Chemistry. 69:480-489
"Anti-infective pregnane steroid from the octocoral Carijoa riisei collected in South Brazil" (2012) de Almeida, M.T.R.;Tonini, M.L.;Guimarães, T.R. (...)Schenkel, E.P. Latin American Journal of Pharmacy. 31(10):1489-1495
"Antiparasitic effect of vitamin B12 on Trypanosoma cruzi" (2012) Ciccarelli, A.B.;Frank, F.M.;Puente, V. (...)Lombardo, M.E. Antimicrobial Agents and Chemotherapy. 56(10):5315-5320
"Kinetoplastids: Related protozoan pathogens, different diseases" (2008) Stuart, K.;Brun, R.;Croft, S. (...)Tarleton, R. Journal of Clinical Investigation. 118(4):1301-1310
"Multiple NADPH-cytochrome P450 reductases from Trypanosoma cruzi. Suggested role on drug resistance" (2008) Portal, P.;Villamil, S.F.;Alonso, G.D. (...)Paveto, C. Molecular and Biochemical Parasitology. 160(1):42-51
"An insight on targets and patented drugs for chemotherapy of chagas disease" (2007) Duschak, V.G.; Couto, A.S. Recent Patents on Anti-Infective Drug Discovery. 2(1):19-51
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral chagas disease in a patient with AIDS" (2005) Burgos, J.M.;Begher, S.B.;Freitas, J.M. (...)Schijman, A.G. American Journal of Tropical Medicine and Hygiene. 73(6):1016-1018
"Specific molecular targets to control tropical diseases" (2001) Rodriguez, J.B. Current Pharmaceutical Design. 7(12):1105-1116
"Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi" (1998) Rodriguez, J.B.;Zhong, L.;Docampo, R. (...)Gros, E.G. Bioorganic and Medicinal Chemistry Letters. 8(22):3257-3260
"Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes)" (1997) Schvartzapel, A.J.;Zhong, L.;Docampo, R. (...)Gros, E.G. Journal of Medicinal Chemistry. 40(15):2314-2322
"Recent developments in the control of Trypanosoma cruzi, the causative agent for Chagas' disease" (1995) Rodriguez, J.B.; Gros, E.G. Current Medicinal Chemistry. 2(3):723-742
"Effects of trypanocidal drugs on protein biosynthesis in vitro and in vivo by Trypanosoma cruzi" (1989) Gonzalez, N.S.; Cazzulo, J.J. Biochemical Pharmacology. 38(17):2873-2877