Registro:

Referencias:

• Chagas, C., Nova tripanozomiaze humana: estudos sobre amorfolojia e o ciclo evolutivo do Schizotrypanum cruzin. gen., n. sp., ajente etiolojico de nova entidade morbidado homem (1909) Mem. Inst. Oswaldo Cruz, 1, pp. 159-218
• Cruz-Reyes, A., Pickering-Lopez, J.M., Chagas disease in Mexico: an analysis of geographical distribution during the past 76 years-a review (2006) Mem. Inst. Oswaldo Cruz, 101, pp. 345-354
• Coura, J.R., Dias, J.C., Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery (2009) Mem. Inst. Oswaldo Cruz, 104, pp. 31-40
• Salomon, C.J., First century of Chagas’ disease: an overview on novel approaches to nifurtimox and benzonidazole delivery systems (2012) J. Pharmacol. Sci., 101, pp. 888-894
• Castro, J.A., deMecca, M.M., Bartel, L.C., Toxic side effects of drugs used to treat Chagas’ disease (American trypanosomiasis) (2006) Hum. Exp. Toxicol., 25, pp. 471-479
• Viotti, R., Vigliano, C., Lococo, B., Alvarez, M.G., Petti, M., Bertocchi, G., Armenti, A., Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities (2009) Expert Rev. Anti Infect. Ther., 7, pp. 157-163
• Altcheh, J., Moscatelli, G., Moroni, S., Bournissen, G.F., Freilij, H., Adverse events after the use of benznidazole in infants and children with Chagas disease (2011) Pediatrics, 127, pp. 212-218
• Santos, V.P., Barrias, E.S., Santos, J.F., Barros Moreira, T.L., De Carvalho, T.M., Urbina, J.A., De Souza, W., Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi (2012) Int. J. Antimicrob. Agents, 40, pp. 61-71
• Chamond, N., Coatnoan, N., Minoprio, P., Immunotherapy of Trypanosoma cruzi infections (2002) Curr. Drug Targets - Immune, Endocr. Metab. Disord., 2, pp. 247-254
• Buschiazzo, A., Amaya, M.F., Cremona, M.L., Frasch, A.C., Alzari, P.M., The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis (2002) Mol. Cell, 31, pp. 757-768
• Amaya, M.F., Watts, A.G., Damager, I., Wehenkel, A., Nguyen, T., Buschiazzo, A., Paris, G., Alzari, P.M., Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase (2004) Structure, 31, pp. 775-784
• Buchini, S., Buschiazzo, A., Withers, S.G., A new generation of specific Trypanosoma cruzi trans-sialidase inhibitors (2008) Angew. Chem. Int. Ed., 25, pp. 2700-2703
• Kashif, M., Herrera, A.M., Lara-Ramirez, E.E., Ramírez-Moreno, E., García, V.B., Ashfaq, M., Rivera, G., Recent developments in trans-sialidase inhibitors of Trypanosoma cruzi (2017) J. Drug Target., 25, pp. 485-498
• Lima, A.H., Lameira, J., Alves, C.N., Protein–ligand interaction of T. cruzi trans-sialidase inhibitors: a docking and QM/MM MD study (2012) Struct. Chem., 1, pp. 147-152
• Neres, J., Bonnet, P., Edwards, P.N., Kotian, P.L., Buschiazzo, A., Alzari, P.M., Douglas, K.T., Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase (2007) Bioorg. Med. Chem., 15, pp. 2106-2119
• Neres, J., Brewer, M.L., Ratier, L., Botti, H., Buschiazzo, A., Edwards, P.N., Mortenson, P.N., Bryce, R.A., Discovery of novel inhibitors of Trypanosoma cruzitrans-sialidase from in silico screening (2009) Bioorganic Med. Chem lett, 1, pp. 589-596
• Kim, J.H., Ryu, H.W., Shim, J.H., Park, K.H., Withers, S.G., Development of new and selective trypanosoma cruzi trans-sialidase inhibitors from sulfonamide chalcones and their derivatives (2009) Chembiochem, 12, pp. 2475-2479
• Arioka, S., Sakagami, M., Uematsu, R., Yamaguchi, H., Togame, H., Takemoto, H., Hinou, H., Nishimura, S.I., Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase (2010) Bioorg. Med. Chem., 15, pp. 1633-1640
• Kashif, M., Moreno-Herrera, A., Villalobos-Rocha, J.C., Nogueda-Torres, B., Pérez-Villanueva, J., Rodríguez-Villar, K., Rivera, G., Benzoic acid derivatives with trypanocidal activity: enzymatic analysis and molecular docking studies toward trans-sialidase (2017) Molecules, 22, p. 1863
• Noguchi, T., Shimazawa, R., Nagasawa, K., Hashimoto, Y., Thalidomide and its analogues as cyclooxygenase inhibitors (2002) Bioorganic Med Chem lett, 12, pp. 1043-1046
• Sano, H., Noguchi, T., Tanatani, A., Hashimoto, Y., Miyachi, H., Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide (2005) Bioorg. Med. Chem., 13, pp. 3079-3091
• Alaa, A.M., ElTahir, K.E., Asiri, Y.A., Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: molecular docking study (2011) Eur. J. Med. Chem., 46, pp. 1648-1655
• Alaa, A.M., El-Azab, A.S., Attia, S.M., Al-Obaid, A.M., Al-Omar, M.A., El-Subbagh, H.I., Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents (2011) Eur. J. Med. Chem., 46, pp. 4324-4329
• Alanazi, A.M., El-Azab, A.S., Al-Suwaidan, I.A., ElTahir, K.E., Asiri, Y.A., Abdel-Aziz, N.I., Alaa, A.M., Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities (2015) Eur. J. Med. Chem., 92, pp. 115-123
• Abdel-Aziz, A.A.M., El-Azab, A.S., Attia, S.M., Al-Obaid, A.M., Al-Omar, M.A., El-Subbagh, H.I., Synthesis and biological evaluation of some novel cyclicimides as hypoglycaemic, anti-hyperlipidemic agents (2011) Eur. J. Med. Chem., 46, pp. 4324-4329
• Alanazi, A.M., El-Azab, A.S., Al-Suwaidan, I.A., ElTahir, K.E.H., Asiri, Y.A., Abdel-Aziz, N.I., Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities (2015) Eur. J. Med. Chem., 92, pp. 115-123
• Abdel-Aziz, A.A.M., El-Azab, A.S., Attia, S.M., Al-Obaid, A.M., Al-Omar, M.A., El-Subbagh, H.I., Synthesis and biological evaluation of some novel cyclicimides as hypoglycaemic, anti-hyperlipidemic agents (2011) Eur. J. Med. Chem., 46, pp. 4324-4329
• Kamiński, K., Obniska, J., Wiklik, B., Atamanyuk, D., Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogs (2011) Eur. J. Med. Chem., 46, pp. 4634-4641
• Akgün, H., Karamelekoğlu, I., Berk, B., Kurnaz, I., Sarıbıyık, G., Öktem, S., Synthesis and antimycobacterial activity of some phthalimide derivatives (2012) Bioorg. Med. Chem., 20, pp. 4149-4154
• Williams, R., Manka, J.T., Rodriguez, A.L., Vinson, P.N., Niswender, C.M., Weaver, C.D., Synthesis and SAR of centrally active mGlu5 positive allosteric modulators based on an aryl acetylenic bicyclic lactam scaffold (2011) Bioorg. Med. Chem. Lett, 21, pp. 1350-1353
• Cardoso, M.V.D.O., Moreira, D.R.M., Filho, G.B.O., Cavalcanti, S.M.T., Coelho, L.C.D., Espíndola, J.W.P., Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities (2015) Eur. J. Med. Chem., 96, pp. 491-503
• Pessoa, C., Ferreira, P.M.P., Lotufo, L.V.C., de Moraes, M.O., Cavalcanti, S.M.T., Coêlho, L.C.D., Discovery of phthalimides as immunomodulatory and antitumor drug prototypes (2010) ChemMedChem, 5, pp. 523-528
• da Costa, P.M., da Costa, M.P., Carvalho, A.A., Cavalcanti, S.M.T., de Oliveira Cardoso, M.V., de Oliveira Filho, G.B., Improvement of in vivo anticancer and antiangiogenic potential of thalidomide derivatives (2015) Chem. Biol. Interact., 239. , 74–183
• de Santiago, E.F., de Oliveira, S.A., de Oliveira Filho, G.B., Moreira, D.R.M., Gomes, P.A.T., da Silva, A.C.L.A.C.L., Evaluation of the anti-schistosoma mansoni activity of thiosemicarbazones and thiazoles (2014) Antimicrob. Agents Chemother., 58, pp. 352-363
• de Moraes Gomes, P.A., Oliveira, A.R., de Oliveira Cardoso, M.V., de Farias Santiago, E., de Oliveira Barbosa, M., de Siqueira, L.R., Moreira, D.R., de Oliveira Mendes, A.P., Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi (2016) Eur. J. Med. Chem., 23. , 46–5
• Lebedev, A.V., Lebedeva, A.B., Sheludyakov, V.D., Kovaleva, E.A., Ustinova, O.L., Kozhevnikov, I.B., Competitive formation of β-amino acids, propenoic, and ylidenemalonic acids by the rodionov reaction from malonic acid, aldehydes, and ammonium acetate in alcoholic medium (2005) Russ. J. Gen. Chem., 75, pp. 1113-1124
• Ashfaq, M., Synthesis of novel bioactive phthalimido-4-methyl pentanoateorganotin (IV) esters with spectroscopic investigation (2006) J. Organomet. Chem., 691, pp. 1803-1808
• Watts, A.G., Damager, I., Amaya, M.L., Buschiazzo, A., Alzari, P., Frasch, A.C., Withers, S.G., Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile (2003) J. Am. Chem. Soc., 125, pp. 7532-7533
• Todeschini, A.R., Mendonça-Previato, L., Previato, J.O., Varki, A., Halbeek, H.V., Trans-sialidase from Trypanosoma cruzi catalyzes sialoside hydrolysis with retention of configuration (2000) Glycobiology, 10, pp. 213-221
• Agustí, R., París, G., Ratier, L., Frasch, A.C.C., de Lederkremer, R.M., Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo (2004) Glycobiology, 14, pp. 659-670
• Morris, G.M., Huey, R., Lindstrom, W., Sanner, M.F., Belew, R.K., Goodsell, D.S., Olson, A.J., AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility (2009) J. Comput. Chem., 16, pp. 2785-2791
• Trott, O., Olson, A.J., AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading (2010) J. Comput. Chem., 31, pp. 455-461
• Dassault Systèmes BIOVIA, Discovery Studio Modeling Environment, Release 2017 (2016), Dassault Systèmes San Diego; Mendoza-Martínez, C., Correa-Basurto, J., Nieto-Meneses, R., Márquez-Navarro, A., Aguilar-Suárez, R., Montero-Cortes, M.D., Nogueda-Torres, B., Rodriguez-Lezama, A., Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents (2015) Eur. J. Med. Chem., 96, pp. 296-307
• Brener, Z., Therapeutic activity and criterion of cure on mice experimentally infected with Trypanosoma cruzi (1962) Rev. Inst. Med. Trop. Sao Paulo, 6, pp. 389-396
• Villalobos-Rocha, J.C., Sánchez-Torres, L., Nogueda-Torres, B., Segura-Cabrera, A., García-Pérez, C.A., Bocanegra-García, V., Palos, I., Rivera, G., Anti-Trypanosoma cruzi and anti-leishmanial activity by quinoxaline-7-carboxylate 1, 4-di-N-oxide derivatives (2014) J Parasitol Res., 113, pp. 2027-2035
• Buschiazzo, A., Frasch, A.C., Campetella, O., Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi (1996) Cell. Mol. Biol., 42, pp. 703-710
• Cano, M.E., Agusti, R., Cagnoni, A.J., Tesoriero, M.F., Kovensky, J., Uhrig, M.L., de Lederkremer, R.M., Synthesis of divalent ligands of β-thio-and β-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase (2014) Beilstein J. Org. Chem., 10, p. 3073

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------