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Antiprotozoal Agents
25
"Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis" (2017) Li, Z.-H.;Li, C.;Szajnman, S.H. (...)Moreno, S.N.J. Antimicrobial Agents and Chemotherapy. 61(8)
"In Vitro and in Vivo activities of sulfur-containing linear bisphosphonates against apicomplexan parasites" (2017) Szajnman, S.H.;Galaka, T.;Li, Z.-H. (...)Rodriguez, J.B. Antimicrobial Agents and Chemotherapy. 61(2)
"An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method" (2017) Lara-Ramirez, E.E.;López-Cedillo, J.C.;Nogueda-Torres, B. (...)Rivera, G. European Journal of Medicinal Chemistry. 132:249-261
"Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi" (2015) García Liñares, G.;Antonela Zígolo, M.;Simonetti, L. (...)Baldessari, A. Bioorganic and Medicinal Chemistry. 23(15):4804-4814
"Aryloxyethyl thiocyanates are potent growth inhibitors of Trypanosoma cruzi and Toxoplasma gondii" (2015) Chao, M.N.;Matiuzzi, C.E.;Storey, M. (...)Rodriguez, J.B. ChemMedChem. 10(6):1094-1108
"Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones" (2014) Martins Alho, M.A.;Marrero-Ponce, Y.;Barigye, S.J. (...)Arán, V.J. Bioorganic and Medicinal Chemistry. 22(5):1568-1585
"Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents" (2013) Recher, M.;Barboza, A.P.;Li, Z.-H. (...)Rodriguez, J.B. European Journal of Medicinal Chemistry. 60:431-440
"Chemoenzymatic synthesis and biological evaluation of 2- and 3-hydroxypyridine derivatives against Leishmania mexicana" (2012) García Liñares, G.; Parraud, G.; Labriola, C.; Baldessari, A. Bioorganic and Medicinal Chemistry. 20(15):4614-4624
"1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase" (2012) Szajnman, S.H.;Rosso, V.S.;Malayil, L. (...)Rodriguez, J.B. Organic and Biomolecular Chemistry. 10(7):1424-1433
"Structural and immunological characterization of sulphatides: Relevance of sulphate moieties in Trypanosoma cruzi glycoconjugates" (2012) Acosta, D.M.;Soprano, L.L.;Ferrero, M.R. (...)Duschak, V.G. Parasite Immunology. 34(11):499-510
"New antibacterials for the treatment of toxoplasmosis; A patent review" (2012) Rodriguez, J.B.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 22(3):311-333
"New acridinone derivative with trypanocidal activity" (2008) Pardo Andreu, G.L.;Inada, N.M.;Pellón, R.F. (...)Vercesi, A.E. International Journal of Antimicrobial Agents. 31(5):502-504
"Kinetoplastids: Related protozoan pathogens, different diseases" (2008) Stuart, K.;Brun, R.;Croft, S. (...)Tarleton, R. Journal of Clinical Investigation. 118(4):1301-1310
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Metronidazole-induced alterations in murine spermatozoa morphology" (2007) Mudry, M.D.; Palermo, A.M.; Merani, M.S.; Carballo, M.A. Reproductive Toxicology. 23(2):246-252
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Triterpenic acids and flavonoids from Satureja parvifolia, evaluation of their antiprotozoal activity" (2006) Van Baren, C.;Anao, I.;Lira, P.D.L. (...)Martino, V. Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 61(3-4):189-192
"Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis" (2006) Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Journal of Medicinal Chemistry. 49(1):426-435
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase" (2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690
"Teratogenic Evaluation of Metronidazole and Ornidazole Using Drosophila melanogaster as an Experimental Model" (2004) Palermo, A.M.;Reynoso, A.S.;López Nigro, M. (...)Mudry, M.D. Birth Defects Research Part A - Clinical and Molecular Teratology. 70(4):157-162
"Specific molecular targets to control tropical diseases" (2001) Rodriguez, J.B. Current Pharmaceutical Design. 7(12):1105-1116
"Glycoinositolphospholipids, free and as anchors of proteins, in trypanosoma" (2001) de Lederkremer, R.M.; Bertello, L.E. Current Pharmaceutical Design. 7(12):1165-1179