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site directed mutagenesis
26
"Hidden Structural Codes in Protein Intrinsic Disorder" (2017) Borkosky, S.S.;Camporeale, G.;Chemes, L.B. (...)De Prat Gay, G. Biochemistry. 56(41):5560-5569
"The Phosphatidylinositol 3-kinase Class III Complex Containing TcVps15 and TcVps34 Participates in Autophagy in Trypanosoma cruzi" (2017) Schoijet, A.C.; Sternlieb, T.; Alonso, G.D. Journal of Eukaryotic Microbiology. 64(3):308-321
"Kinetics, subcellular localization, and contribution to parasite virulence of a Trypanosoma cruzi hybrid type A heme peroxidase (TcAPx-CcP)" (2017) Hugo, M.;Martínez, A.;Trujillo, M. (...)Radi, R. Proceedings of the National Academy of Sciences of the United States of America. 114(8):E1326-E1335
"Differential contribution of subunit interfaces to α9α10 nicotinic acetylcholine receptor function" (2017) Boffi, J.C.;Marcovich, I.;Gill-Thind, J.K. (...)Elgoyhen, A.B. Molecular Pharmacology. 91(3):250-262
"Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications" (2016) Álvarez, L.;Lewis-Ballester, A.;Roitberg, A. (...)Capece, L. Biochemistry. 55(19):2785-2793
"Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications" (2016) Álvarez, L.;Lewis-Ballester, A.;Roitberg, A. (...)Capece, L. Biochemistry. 55(19):2785-2793
"Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: Role of the CD loop and Pre-A motif in electron cycling" (2014) Singh, S.;Thakur, N.;Oliveira, A. (...)Dikshit, K.L. Journal of Biological Chemistry. 289(31):21573-21583
"Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: Role of the CD loop and Pre-A motif in electron cycling" (2014) Singh, S.;Thakur, N.;Oliveira, A. (...)Dikshit, K.L. Journal of Biological Chemistry. 289(31):21573-21583
"Interplay of the H-bond donor-acceptor role of the distal residues in hydroxyl ligand stabilization of Thermobifida fusca truncated hemoglobin" (2014) Nicoletti, F.P.;Bustamante, J.P.;Droghetti, E. (...)Smulevich, G. Biochemistry. 53(51):8021-8030
"Small ligand-globin interactions: Reviewing lessons derived from computer simulation" (2013) Capece, L.;Boechi, L.;Perissinotti, L.L. (...)Estrin, D.A. Biochimica et Biophysica Acta - Proteins and Proteomics. 1834(9):1722-1738
"Functional characterization of residues involved in redox modulation of maize photosynthetic NADP-Malic enzyme activity" (2012) Alvarez, C.E.;Detarsio, E.;Moreno, S. (...)Drincovich, M.F. Plant and Cell Physiology. 53(6):1144-1153
"Mutational analysis of kinetic partitioning in protein folding and protein-DNA binding" (2011) Sánchez, I.E.; Ferreiro, D.U.; De Prat Gay, G. Protein Engineering, Design and Selection. 24(1-2):179-184
"Mutational analysis of kinetic partitioning in protein folding and protein-DNA binding" (2011) Sánchez, I.E.; Ferreiro, D.U.; De Prat Gay, G. Protein Engineering, Design and Selection. 24(1-2):179-184
"Mutations in two putative phosphorylation motifs in the tomato pollen receptor kinase LePRK2 show antagonistic effects on pollen tube length" (2011) Salem, T.;Mazzella, A.;Barberini, M.L. (...)Muschietti, J. Journal of Biological Chemistry. 286(6):4882-4891
"Mutations in two putative phosphorylation motifs in the tomato pollen receptor kinase LePRK2 show antagonistic effects on pollen tube length" (2011) Salem, T.;Mazzella, A.;Barberini, M.L. (...)Muschietti, J. Journal of Biological Chemistry. 286(6):4882-4891
"The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer" (2010) Stojković, V.;Perissinotti, L.L.;Lee, J. (...)Kohen, A. Chemical Communications. 46(47):8974-8976
"The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins" (2009) Smal, C.;Wetzler, D.E.;Dantur, K.I. (...)De Prat-Gay, G. Biochemistry. 48(50):11939-11949
"New insights into the regulation of the Saccharomyces cerevisiae UGA54 gene: Two parallel pathways participate in carbon-regulated transcription" (2007) Luzzani, C.; Cardillo, S.B.; Moretti, M.B.; García, S.C. Microbiology. 153(11):3677-3684
"Two distinct heme distal site states define Cerebratulus lacteus mini-hemoglobin oxygen affinity" (2006) Martí, M.A.;Bikiel, D.E.;Crespo, A. (...)Estrin, D.A. Proteins: Structure, Function and Genetics. 62(3):641-648