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Trypanocidal Agents
25
"Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase" (2018) Kashif, M.;Chacón-Vargas, K.F.;López-Cedillo, J.C. (...)Rivera, G. European Journal of Medicinal Chemistry. 156:252-268
"Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi" (2018) Puente, V.;Demaria, A.;Frank, F.M. (...)Lombardo, M.E. PLoS Neglected Tropical Diseases. 12(9)
"Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation" (2017) Chao, M.N.;Storey, M.;Li, C. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 25(24):6435-6449
"Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015)" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 26(9):993-1015
"WC-9 a lead drug with great prospects for American trypanosomiasis and toxoplasmosis" (2016) Rodriguez, J.B. Mini-Reviews in Medicinal Chemistry. 16(15):1195-1200
"Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with in vitro antiplasmodial and antitrypanosomal activities" (2015) Leverrier, A.;Bero, J.;Cabrera, J. (...)Palermo, J.A. European Journal of Medicinal Chemistry. 100(1):10-17
"Trypanosoma cruzi infection in Triatoma sordida before and after community-wide residual insecticide spraying in the Argentinean Chaco" (2015) Macchiaverna, N.P.;Gaspe, M.S.;Enriquez, G.F. (...)Cardinal, M.V. Acta Tropica. 143:97-102
"Preparation and antitrypanosomal activity of secochiliolide acid derivatives" (2013) Siless, G.E.;Lozano, E.;Sánchez, M. (...)Palermo, J.A. Bioorganic and Medicinal Chemistry Letters. 23(17):4964-4967
"2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase" (2012) Rodrígues-Poveda, C.A.; González-Pacanowska, D.; Szajnman, S.H.; Rodríguez, J.B. Antimicrobial Agents and Chemotherapy. 56(8):4483-4486
"Antiparasitic effect of vitamin B12 on Trypanosoma cruzi" (2012) Ciccarelli, A.B.;Frank, F.M.;Puente, V. (...)Lombardo, M.E. Antimicrobial Agents and Chemotherapy. 56(10):5315-5320
"In vitro effect of a new cinnamic acid derivative against the epimastigote form of Trypanosoma cruzi" (2009) Andreu, G.L.P.;Inada, N.M.;Pellón, R.F. (...)Vercesi, A.E. Arzneimittel-Forschung/Drug Research. 59(4):207-211
"Trypanosoma cruzi: In vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg)" (2007) Güida, M.C.;Esteva, M.I.;Camino, A. (...)Paveto, C. Experimental Parasitology. 117(2):188-194
"An insight on targets and patented drugs for chemotherapy of chagas disease" (2007) Duschak, V.G.; Couto, A.S. Recent Patents on Anti-Infective Drug Discovery. 2(1):19-51
"The genome sequence of Trypanosoma cruzi, etiologic agent of chagas disease" (2005) El-Sayed, N.M.;Myler, P.J.;Bartholomeu, D.C. (...)Andersson, B. Science. 309(5733):409-415+435
"Anti-Trypanosoma cruzi Activity of Green Tea (Camellia sinensis) Catechins" (2004) Paveto, C.;Güida, M.C.;Esteva, M.I. (...)Torres, H.N. Antimicrobial Agents and Chemotherapy. 48(1):69-74
"Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease" (2003) Urbina, J.A.;Concepcion, J.L.;Montalvetti, A. (...)Docampo, R. Antimicrobial Agents and Chemotherapy. 47(6):2047-2050
"Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi" (2002) Elhalem, E.;Bailey, B.N.;Docampo, R. (...)Rodriguez, J.B. Journal of Medicinal Chemistry. 45(18):3984-3999
"Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi" (2001) Szajnman, S.H.; Bailey, B.N.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 11(6):789-792
"Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation" (2000) Szajnman, S.H.;Yan, W.;Bailey, B.N. (...)Rodriguez, J.B. Journal of Medicinal Chemistry. 43(9):1826-1840
"Structure-activity relationship of new growth inhibitors of Trypanosoma cruzi" (1998) Cinque, G.M.;Szajnman, S.H.;Zhong, L. (...)Gros, E.G. Journal of Medicinal Chemistry. 41(9):1540-1554
"Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes)" (1997) Schvartzapel, A.J.;Zhong, L.;Docampo, R. (...)Gros, E.G. Journal of Medicinal Chemistry. 40(15):2314-2322
"Effects of Juvenile Hormone Analogues (JHA) on the Development of Trypanosoma cruzi" (1995) Fichera, L.;Esteva, M.;Wimmer, Z. (...)Gros, E.G. Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 50(7-8):578-580
"Effects of trypanocidal drugs on protein biosynthesis in vitro and in vivo by Trypanosoma cruzi" (1989) Gonzalez, N.S.; Cazzulo, J.J. Biochemical Pharmacology. 38(17):2873-2877