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geranyltransferase
17
"The Role of the Phosphorus Atom in Drug Design" (2019) Rodriguez, J.B.; Gallo-Rodriguez, C. ChemMedChem. 14(2):190-216
"In Vitro and in Vivo activities of sulfur-containing linear bisphosphonates against apicomplexan parasites" (2017) Szajnman, S.H.;Galaka, T.;Li, Z.-H. (...)Rodriguez, J.B. Antimicrobial Agents and Chemotherapy. 61(2)
"Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis" (2017) Li, Z.-H.;Li, C.;Szajnman, S.H. (...)Moreno, S.N.J. Antimicrobial Agents and Chemotherapy. 61(8)
"Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015)" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 26(9):993-1015
"Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Drug Discovery. 11(3):307-320
"New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase" (2014) Ferrer-Casal, M.;Li, C.;Galizzi, M. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 22(1):398-405
"Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents" (2013) Recher, M.;Barboza, A.P.;Li, Z.-H. (...)Rodriguez, J.B. European Journal of Medicinal Chemistry. 60:431-440
"1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase" (2012) Szajnman, S.H.;Rosso, V.S.;Malayil, L. (...)Rodriguez, J.B. Organic and Biomolecular Chemistry. 10(7):1424-1433
"2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase" (2012) Rodrígues-Poveda, C.A.; González-Pacanowska, D.; Szajnman, S.H.; Rodríguez, J.B. Antimicrobial Agents and Chemotherapy. 56(8):4483-4486
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Characterization of the farnesyl pyrophosphate synthase of Trypanosoma cruzi by homology modeling and molecular dynamics" (2006) Sigman, L.; Sánchez, V.M.; Turjanski, A.G. Journal of Molecular Graphics and Modelling. 25(3):345-352
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase" (2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690
"Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase" (2003) Szajnman, S.H.;Montalvetti, A.;Wang, Y. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 13(19):3231-3235