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Bisphosphonates
16
"The Role of the Phosphorus Atom in Drug Design" (2019) Rodriguez, J.B.; Gallo-Rodriguez, C. ChemMedChem. 14(2):190-216
"In Vitro and in Vivo activities of sulfur-containing linear bisphosphonates against apicomplexan parasites" (2017) Szajnman, S.H.;Galaka, T.;Li, Z.-H. (...)Rodriguez, J.B. Antimicrobial Agents and Chemotherapy. 61(2)
"The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase" (2016) Valsecchi, W.M.;Cousido-Siah, A.;Defelipe, L.A. (...)Delfino, J.M. Biochimica et Biophysica Acta - Proteins and Proteomics. 1864(6):655-666
"Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Drug Discovery. 11(3):307-320
"New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase" (2014) Ferrer-Casal, M.;Li, C.;Galizzi, M. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 22(1):398-405
"New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase" (2014) Ferrer-Casal, M.;Li, C.;Galizzi, M. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 22(1):398-405
"1,3-dipolar cycloadditions of the versatile intermediate tetraethyl vinylidenebisphosphonate" (2013) Ferrer-Casal, M.; Barboza, A.P.; Szajnman, S.H.; Rodriguez, J.B. Synthesis (Germany). 45(17):2397-2404
"1,3-dipolar cycloadditions of the versatile intermediate tetraethyl vinylidenebisphosphonate" (2013) Ferrer-Casal, M.; Barboza, A.P.; Szajnman, S.H.; Rodriguez, J.B. Synthesis (Germany). 45(17):2397-2404
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Characterization of the farnesyl pyrophosphate synthase of Trypanosoma cruzi by homology modeling and molecular dynamics" (2006) Sigman, L.; Sánchez, V.M.; Turjanski, A.G. Journal of Molecular Graphics and Modelling. 25(3):345-352
"Characterization of the farnesyl pyrophosphate synthase of Trypanosoma cruzi by homology modeling and molecular dynamics" (2006) Sigman, L.; Sánchez, V.M.; Turjanski, A.G. Journal of Molecular Graphics and Modelling. 25(3):345-352
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase" (2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690