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antiprotozoal agent
19
"Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis" (2017) Li, Z.-H.;Li, C.;Szajnman, S.H. (...)Moreno, S.N.J. Antimicrobial Agents and Chemotherapy. 61(8)
"Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis" (2017) Li, Z.-H.;Li, C.;Szajnman, S.H. (...)Moreno, S.N.J. Antimicrobial Agents and Chemotherapy. 61(8)
"In Vitro and in Vivo activities of sulfur-containing linear bisphosphonates against apicomplexan parasites" (2017) Szajnman, S.H.;Galaka, T.;Li, Z.-H. (...)Rodriguez, J.B. Antimicrobial Agents and Chemotherapy. 61(2)
"An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method" (2017) Lara-Ramirez, E.E.;López-Cedillo, J.C.;Nogueda-Torres, B. (...)Rivera, G. European Journal of Medicinal Chemistry. 132:249-261
"A new type of quinoxalinone derivatives affects viability, invasion, and intracellular growth of Toxoplasma gondii tachyzoites in vitro" (2016) Rivera Fernández, N.;Mondragón Castelán, M.;González Pozos, S. (...)Mondragón Flores, R. Parasitology Research. 115(5):2081-2096
"Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi" (2015) García Liñares, G.;Antonela Zígolo, M.;Simonetti, L. (...)Baldessari, A. Bioorganic and Medicinal Chemistry. 23(15):4804-4814
"Aryloxyethyl thiocyanates are potent growth inhibitors of Trypanosoma cruzi and Toxoplasma gondii" (2015) Chao, M.N.;Matiuzzi, C.E.;Storey, M. (...)Rodriguez, J.B. ChemMedChem. 10(6):1094-1108
"Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones" (2014) Martins Alho, M.A.;Marrero-Ponce, Y.;Barigye, S.J. (...)Arán, V.J. Bioorganic and Medicinal Chemistry. 22(5):1568-1585
"Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones" (2014) Martins Alho, M.A.;Marrero-Ponce, Y.;Barigye, S.J. (...)Arán, V.J. Bioorganic and Medicinal Chemistry. 22(5):1568-1585
"Anti-infective pregnane steroid from the octocoral Carijoa riisei collected in South Brazil" (2012) de Almeida, M.T.R.;Tonini, M.L.;Guimarães, T.R. (...)Schenkel, E.P. Latin American Journal of Pharmacy. 31(10):1489-1495
"1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase" (2012) Szajnman, S.H.;Rosso, V.S.;Malayil, L. (...)Rodriguez, J.B. Organic and Biomolecular Chemistry. 10(7):1424-1433
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Triterpenic acids and flavonoids from Satureja parvifolia, evaluation of their antiprotozoal activity" (2006) Van Baren, C.;Anao, I.;Lira, P.D.L. (...)Martino, V. Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 61(3-4):189-192
"Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease" (2003) Urbina, J.A.;Concepcion, J.L.;Montalvetti, A. (...)Docampo, R. Antimicrobial Agents and Chemotherapy. 47(6):2047-2050
"Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation" (2000) Szajnman, S.H.;Yan, W.;Bailey, B.N. (...)Rodriguez, J.B. Journal of Medicinal Chemistry. 43(9):1826-1840