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Guanine Nucleotide Exchange Factors
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"Host Epac1 is required for cAMP-mediated invasion by Trypanosoma cruzi" (2017) Musikant, D.;Ferri, G.;Durante, I.M. (...)Edreira, M.M. Molecular and Biochemical Parasitology. 211:67-70
"Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling" (2016) Inda, C.;Claro, P.A.S.;Bonfiglio, J.J. (...)Silberstein, S. Journal of Cell Biology. 214(2):181-195
"Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition" (2015) Doncic, A.;Atay, O.;Valk, E. (...)Skotheim, J.M. Cell. 160(6):1182-1195
"Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines" (2014) Cardama, G.A.;Comin, M.J.;Hornos, L. (...)Menna, P.L. Anti-Cancer Agents in Medicinal Chemistry. 14(6):840-851
"Exchange protein activated by cyclic AMP is involved in the regulation of adipogenic genes during 3T3-L1 fibroblasts differentiation" (2014) Gabrielli, M.;Martini, C.N.;Brandani, J.N. (...)Vila, M.D.C. Development Growth and Differentiation. 56(2):143-151
"The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells" (2012) Maymó, J.L.;Pérez Pérez, A.;Maskin, B. (...)Varone, C.L. PLoS ONE. 7(10)
"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746