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antiprotozoal activity
19
"Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents" (2019) Chanquia, S.N.;Larregui, F.;Puente, V. (...)García Liñares, G. Bioorganic Chemistry. 83:526-534
"Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation" (2017) Chao, M.N.;Storey, M.;Li, C. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 25(24):6435-6449
"A new type of quinoxalinone derivatives affects viability, invasion, and intracellular growth of Toxoplasma gondii tachyzoites in vitro" (2016) Rivera Fernández, N.;Mondragón Castelán, M.;González Pozos, S. (...)Mondragón Flores, R. Parasitology Research. 115(5):2081-2096
"Aryloxyethyl thiocyanates are potent growth inhibitors of Trypanosoma cruzi and Toxoplasma gondii" (2015) Chao, M.N.;Matiuzzi, C.E.;Storey, M. (...)Rodriguez, J.B. ChemMedChem. 10(6):1094-1108
"Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with in vitro antiplasmodial and antitrypanosomal activities" (2015) Leverrier, A.;Bero, J.;Cabrera, J. (...)Palermo, J.A. European Journal of Medicinal Chemistry. 100(1):10-17
"Antiparasitic hybrids of Cinchona alkaloids and bile acids" (2013) Leverrier, A.;Bero, J.;Frédérich, M. (...)Palermo, J. European Journal of Medicinal Chemistry. 66:355-363
"Anti-infective pregnane steroid from the octocoral Carijoa riisei collected in South Brazil" (2012) de Almeida, M.T.R.;Tonini, M.L.;Guimarães, T.R. (...)Schenkel, E.P. Latin American Journal of Pharmacy. 31(10):1489-1495
"Discovery of novel trichomonacidals using LDA-driven QSAR models and bond-based bilinear indices as molecular descriptors" (2009) Rivera-Barroto, O.M.;Marrero-Ponce, Y.;Meneses-Marcel, A. (...)Vogel, C. QSAR and Combinatorial Science. 28(1):9-26
"In vitro effect of a new cinnamic acid derivative against the epimastigote form of Trypanosoma cruzi" (2009) Andreu, G.L.P.;Inada, N.M.;Pellón, R.F. (...)Vercesi, A.E. Arzneimittel-Forschung/Drug Research. 59(4):207-211
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"New acridinone derivative with trypanocidal activity" (2008) Pardo Andreu, G.L.;Inada, N.M.;Pellón, R.F. (...)Vercesi, A.E. International Journal of Antimicrobial Agents. 31(5):502-504
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis" (2006) Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Journal of Medicinal Chemistry. 49(1):426-435
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase" (2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690
"Anti-Trypanosoma cruzi Activity of Green Tea (Camellia sinensis) Catechins" (2004) Paveto, C.;Güida, M.C.;Esteva, M.I. (...)Torres, H.N. Antimicrobial Agents and Chemotherapy. 48(1):69-74
"Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease" (2003) Urbina, J.A.;Concepcion, J.L.;Montalvetti, A. (...)Docampo, R. Antimicrobial Agents and Chemotherapy. 47(6):2047-2050
"Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi" (2002) Elhalem, E.;Bailey, B.N.;Docampo, R. (...)Rodriguez, J.B. Journal of Medicinal Chemistry. 45(18):3984-3999
"Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation" (2000) Szajnman, S.H.;Yan, W.;Bailey, B.N. (...)Rodriguez, J.B. Journal of Medicinal Chemistry. 43(9):1826-1840
"Sensitivity of trypanosomatid protozoa to DFMO and metabolic turnover of ornithine decarboxylase" (2000) Carrillo, C.;Cejas, S.;Cortés, M. (...)Algranati, I.D. Biochemical and Biophysical Research Communications. 279(2):663-668