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cucurbitacin
10
"Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model" (2017) Marostica, L.L.;de Barros, A.L.B.;Oliveira, J. (...)Simões, C.M.O. Toxicology and Applied Pharmacology. 329:272-281
"Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549" (2016) Silva, I.T.;Geller, F.C.;Persich, L. (...)Simões, C.M.O. Investigational New Drugs. 34(2):139-148
"Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549" (2016) Silva, I.T.;Geller, F.C.;Persich, L. (...)Simões, C.M.O. Investigational New Drugs. 34(2):139-148
"In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B" (2015) Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. PLoS ONE. 10(2)
"Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549" (2015) Marostica, L.L.;Silva, I.T.;Kratz, J.M. (...)Simões, C.M.O. Chemical Research in Toxicology. 28(10):1949-1960
"Evaluation of cytotoxic activity of cucurbitacins and their semisynthetic derivatives" (2014) Da-Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. Vitae. 21:S25
"Chemical modification produces species-specific changes in cucurbitacin antifeedant effect" (2013) Lang, K.L.;Deagosto, E.;Zimmermann, L.A. (...)Rossini, C. Journal of Agricultural and Food Chemistry. 61(23):5534-5539
"Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn" (2013) Silva, I.T.;Teixeira, C.R.;Lang, K.L. (...)Simões, C.M.O. International Journal of Cancer Research. 9(2):54-68
"Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives" (2012) Lang, K.L.;Silva, I.T.;Zimmermann, L.A. (...)Durán, F.J. Bioorganic and Medicinal Chemistry. 20(9):3016-3030
"New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn" (2011) Lang, K.L.;Da Rosa Guimarães, T.;Rocha MacHado, V. (...)Schenkel, E.P. Planta Medica. 77(14):1648-1651