Analgesic antipyretics are the most widely used, misused and abused pharmaceutical drugs today. As this group of substances may cause serious intoxications, their analytical investigation is of interest to the toxicologist. Most previous papers were concerned with the indentification of any definite drug of this group. Therefore, an analytical procedure was designed to make a systematic search, consisting largely of a screening with chromogenic reagents and a later identification of the compounds by thin layer chromatography and ultraviolet absorption curves.
| Documento: | Artículo |
| Título: | Identification of antipyretic analgetics |
| Autor: | Graells De Kempny, R.S.; Lourdes Paviolo, M.J.; De Simoni, B.D. |
| Filiación: | Dept. Quim. Biol., Fac. Ci. Exactas Naturales, Univ. Buenos Aires, Argentina |
| Palabras clave: | acetylsalicylic acid; aminophenazone; analgesic agent; antipyretic agent; dipyrone; oxyphenbutazone; phenacetin; phenazone; phenylbutazone; blood analysis; chromatography; drug analysis; drug dependence; drug identification; methodology; thin layer chromatography; ultraviolet spectrophotometry; urinalysis |
| Año: | 1973 |
| Volumen: | 7 |
| Número: | 3 |
| Página de inicio: | 261 |
| Página de fin: | 270 |
| Título revista: | BIOQUIM.CLIN. |
| Título revista abreviado: | BIOQUIM.CLIN. |
| CODEN: | BQCLA |
| CAS: | acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; aminophenazone, 58-15-1, 8058-63-7; dipyrone, 50567-35-6, 5907-38-0, 68-89-3; oxyphenbutazone, 129-20-4; phenacetin, 62-44-2; phenazone, 60-80-0; phenylbutazone, 129-18-0, 50-33-9, 8054-70-4 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_NIS18719_v7_n3_p261_GraellsDeKempny |
