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Abstract:

CaV2.1 (P/Q type) Ca2+ channels have a fundamental role mediating fast transmitter release at central and peripheral synaptic terminals. Various neurological diseases have been attributed to genetic and autoimmune malfunctioning of P/Q channels, including ataxia, migraine and myasthenic syndromes. This chapter focuses on recent advances on the understanding of the pathogenic mechanisms underlying these disorders. © Springer Science+Business Media Dordrecht 2013. All rights are reserved.

Registro:

Documento: Parte de libro
Título:CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases
Autor:Uchitel, O.D.
Filiación:Instituto de Fisiología, Biología Molecular y Neurociencias- CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Ataxia; CaV2.1 subunits; Channelopathy; Migraine; Myasthenic syndromes; P/Q type current
Año:2013
Volumen:9789400763340
Página de inicio:263
Página de fin:288
DOI: http://dx.doi.org/10.1007/978-94-007-6334-0_12
Título revista:Modulation of Presynaptic Calcium Channels
Título revista abreviado:Modulation of Presynaptic Calcium Channels
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97894007_v9789400763340_n_p263_Uchitel

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Citas:

---------- APA ----------
(2013) . CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases. Modulation of Presynaptic Calcium Channels, 9789400763340, 263-288.
http://dx.doi.org/10.1007/978-94-007-6334-0_12
---------- CHICAGO ----------
Uchitel, O.D. "CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases" . Modulation of Presynaptic Calcium Channels 9789400763340 (2013) : 263-288.
http://dx.doi.org/10.1007/978-94-007-6334-0_12
---------- MLA ----------
Uchitel, O.D. "CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases" . Modulation of Presynaptic Calcium Channels, vol. 9789400763340, 2013, pp. 263-288.
http://dx.doi.org/10.1007/978-94-007-6334-0_12
---------- VANCOUVER ----------
Uchitel, O.D. CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases. Modulation of Presynaptic Calcium Channels. 2013;9789400763340:263-288.
http://dx.doi.org/10.1007/978-94-007-6334-0_12