Parte de libro

Renner, U.; Sapochnik, M.; Lucia, K.; Stalla, G.K.; Arzt, E."Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs" (2017) Endocrine Immunology. 48:37-47
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Abstract:

Endotoxin (lipopolysaccharide, LPS) of gram-negative bacteria has been recognized for more than 40 years as a modulator of anterior pituitary hormone production. The action of LPS was thought to be predominantly mediated through LPS-stimulated immune cell-derived cytokines, and is part of the concept of immune-endocrine crosstalk, which regulates bidirectional adaptive processes between the endocrine and immune systems during inflammatory or infectious processes. With the detection of innate immune system components in the normal and tumoral pituitary, including the Toll-like receptor 4, the target of LPS, it has become evident that LPS can directly modify the physiology and pathophysiology of the anterior pituitary. LPS-induced intrapituitary mechanisms involve the stimulation of intrapituitary cytokines, and also directly act on hormone synthesis, growth, and apoptosis of endocrine cells. This review focuses on the effects of LPS on pituitary physiology, its interaction with pro- and anti-inflammatory factors, and the molecular mechanisms involved in these processes. © 2017 S. Karger AG, Basel. All rights reserved.

Registro:

Documento: Parte de libro
Título:Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs
Autor:Renner, U.; Sapochnik, M.; Lucia, K.; Stalla, G.K.; Arzt, E.
Filiación:Max Planck Institute of Psychiatry, Neuroendocrinology Group, Munich, Germany
Instituto de Investigacion en Biomedicina de Buenos Aires (IBioBA), CONICET, Partner Institute of the Max Planck Society, Germany
Departamento de Fisiologia y Biologia Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:lipopolysaccharide; animal; human; hypophysis; immunology; innate immunity; physiology; Animals; Humans; Immunity, Innate; Lipopolysaccharides; Pituitary Gland
Año:2017
Volumen:48
Página de inicio:37
Página de fin:47
DOI: http://dx.doi.org/10.1159/000452904
Handle:http://hdl.handle.net/20.500.12110/paper_97833180_v48_n_p37_Renner
Título revista:Endocrine Immunology
Título revista abreviado:Endocr. Immunol.
CAS:Lipopolysaccharides
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97833180_v48_n_p37_Renner

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Citas:

---------- APA ----------
Renner, U., Sapochnik, M., Lucia, K., Stalla, G.K. & Arzt, E. (2017) . Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs. Endocrine Immunology, 48, 37-47.
http://dx.doi.org/10.1159/000452904
---------- CHICAGO ----------
Renner, U., Sapochnik, M., Lucia, K., Stalla, G.K., Arzt, E. "Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs" . Endocrine Immunology 48 (2017) : 37-47.
http://dx.doi.org/10.1159/000452904
---------- MLA ----------
Renner, U., Sapochnik, M., Lucia, K., Stalla, G.K., Arzt, E. "Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs" . Endocrine Immunology, vol. 48, 2017, pp. 37-47.
http://dx.doi.org/10.1159/000452904
---------- VANCOUVER ----------
Renner, U., Sapochnik, M., Lucia, K., Stalla, G.K., Arzt, E. Intrahypophyseal immune-endocrine interactions: Endocrine integration of the inflammatory inputs. Endocr. Immunol. 2017;48:37-47.
http://dx.doi.org/10.1159/000452904