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Urbano, F.J.; Bisagno, V.; Garcia-Rill, E. "Drug Abuse and the RAS" (2015) Waking and the Reticular Activating System in Health and Disease:277-289
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Abstract:

Interactions between the pedunculopontine (PPN) and ventral tegmental area (VTA) have been described as key brain circuitry that mediates psychostimulant-mediated reward. Intranuclear PPN/laterodorsal tegmental injections of cholinergic receptor agonists or antagonists have helped clarify the role of these nuclei on psychostimulant-induced locomotion. Also, nicotine has been shown to have an inhibitory effect on the PPN, at least initially reducing arousal. PPN activation has been involved in the animal's voluntary search for psychostimulants. On the other hand, CNS depressants like ethanol might reduce arousal by a mechanism involving the direct inhibition of the PPN. In conclusion, neural activity in the PPN is key not only to maintaining arousal but also to affecting the level of psychostimulant and depressant administration. © 2015 Elsevier Inc. All rights reserved.

Registro:

Documento: Parte de libro
Título:Drug Abuse and the RAS
Autor:Urbano, F.J.; Bisagno, V.; Garcia-Rill, E.
Filiación:Laboratorio Fisiologia y Biologia Molecular, Facultad Ciencias Exactas, Ciudad Universitaria, Buenos Aires, Argentina
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, United States
Palabras clave:Amphetamine; Benzodiazepines; Cocaine; Dopamine; Nicotine; Psychostimulant; Tobacco
Año:2015
Página de inicio:277
Página de fin:289
DOI: http://dx.doi.org/10.1016/B978-0-12-801385-4.00013-6
Título revista:Waking and the Reticular Activating System in Health and Disease
Título revista abreviado:Waking and the Reticular Act. Syst. in Health and Dis.
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97801280_v_n_p277_Urbano

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Citas:

---------- APA ----------
Urbano, F.J., Bisagno, V. & Garcia-Rill, E. (2015) . Drug Abuse and the RAS. Waking and the Reticular Activating System in Health and Disease, 277-289.
http://dx.doi.org/10.1016/B978-0-12-801385-4.00013-6
---------- CHICAGO ----------
Urbano, F.J., Bisagno, V., Garcia-Rill, E. "Drug Abuse and the RAS" . Waking and the Reticular Activating System in Health and Disease (2015) : 277-289.
http://dx.doi.org/10.1016/B978-0-12-801385-4.00013-6
---------- MLA ----------
Urbano, F.J., Bisagno, V., Garcia-Rill, E. "Drug Abuse and the RAS" . Waking and the Reticular Activating System in Health and Disease, 2015, pp. 277-289.
http://dx.doi.org/10.1016/B978-0-12-801385-4.00013-6
---------- VANCOUVER ----------
Urbano, F.J., Bisagno, V., Garcia-Rill, E. Drug Abuse and the RAS. Waking and the Reticular Act. Syst. in Health and Dis. 2015:277-289.
http://dx.doi.org/10.1016/B978-0-12-801385-4.00013-6