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Referencias:

• Kornblihtt, A.R., Schor, I.E., Alló, M., Dujardin, G., Petrillo, E., Muñoz, M.J., Alternative splicing: a pivotal step between eukaryotic transcription and translation (2013) Nat Rev Mol Cell Biol, 14, pp. 153-165
• Wang, E.T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S.F., Burge, C.B., Alternative isoform regulation in human tissue transcriptomes (2008) Nature, 456, pp. 470-476
• Srebrow, A., Kornblihtt, A.R., The connection between splicing and cancer (2006) J Cell Sci, 119, pp. 2635-2641
• Novoyatleva, T., Tang, Y., Rafalska, I., Stamm, S., Pre-mRNA missplicing as a cause of human disease (2006) Prog Mol Subcell Biol, 44, pp. 27-46
• Ward, A.J., Cooper, T.A., The pathobiology of splicing (2010) J Pathol, 220, pp. 152-163
• Will, C.L., Lührmann, R., Spliceosome structure and function (2011) Cold Spring Harb Perspect Biol, 3, pp. 1-2
• Naftelberg, S., Schor, I.E., Ast, G., Kornblihtt, A.R., Regulation of alternative splicing through coupling with transcription and chromatin structure (2015) Annu Rev Biochem, 84, pp. 165-198
• Gómez Acuña, L.I., Fiszbein, A., Alló, M., Schor, I.E., Kornblihtt, A.R., Connections between chromatin signatures and splicing (2013) Wiley Interdiscip Rev RNA, 4, pp. 77-91
• Yan, C., Hang, J., Wan, R., Huang, M., Wong, C.C.S.Y., Structure of a yeast spliceosome at 3.6-angstrom resolution (2015) Science, pp. 1-16
• Hang, J., Wan, R., Yan, C., Structural basis of pre-mRNA splicing (2015) Science, 349, pp. 1191-1198
• Cramer, P., Pesce, C.G., Baralle, F.E., Kornblihtt, A.R., Functional association between promoter structure and transcript alternative splicing (1997) Proc Natl Acad Sci USA, 94, pp. 11456-11460
• Cramer, P., Cáceres, J.F., Cazalla, D., Kadener, S., Muro, A.F., Baralle, F.E., Kornblihtt, A.R., Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer (1999) Mol Cell, 4, pp. 251-258
• Beyer, A.L., Osheim, Y.N., Splice site selection, rate of splicing, and alternative splicing on nascent transcripts (1988) Genes Dev, 2, pp. 754-765
• Ameur, A., Zaghlool, A., Halvardson, J., Wetterbom, A., Gyllensten, U., Cavelier, L., Feuk, L., Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain (2011) Nat Struct Mol Biol, 18, pp. 1435-1440
• Brugiolo, M., Herzel, L., Neugebauer, K.M., Counting on co-transcriptional splicing (2013) F1000Prime Rep, 5, p. 9
• Carrillo Oesterreich, F., Preibisch, S., Neugebauer, K.M., Global analysis of nascent RNA reveals transcriptional pausing in terminal exons (2010) Mol Cell, 40, pp. 571-581
• Tardiff, D.F., Lacadie, S.A., Rosbash, M., A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional (2006) Mol Cell, 24, pp. 917-929
• Baurén, G., Wieslander, L., Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription (1994) Cell, 76, pp. 183-192
• Pandya-Jones, A., Black, D.L., Co-transcriptional splicing of constitutive and alternative exons (2009) RNA, 15, pp. 1896-1908
• De la Mata, M., Lafaille, C., Kornblihtt, A.R., First come, first served revisited: factors affecting the same alternative splicing event have different effects on the relative rates of intron removal (2010) RNA, 16, pp. 904-912
• Gerber, H.P., Hagmann, M., Seipel, K., Georgiev, O., West, M.A., Litingtung, Y., Schaffner, W., Corden, J.L., RNA polymerase II C-terminal domain required for enhancer-driven transcription (1995) Nature, 374, pp. 660-662
• McCracken, S., Fong, N., Rosonina, E., Yankulov, K., Brothers, G., Siderovski, D., Hessel, A., Bentley, D.L., 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II (1997) Genes Dev, 11, pp. 3306-3318
• McCracken, S., Fong, N., Yankulov, K., Ballantyne, S., Pan, G., Greenblatt, J., Patterson, S.D., Bentley, D.L., The C-terminal domain of RNA polymerase II couples mRNA processing to transcription (1997) Nature, 385, pp. 357-361
• Muñoz, M.J., de la Mata, M., Kornblihtt, A.R., The carboxy terminal domain of RNA polymerase II and alternative splicing (2010) Trends Biochem Sci, 35, pp. 497-504
• Buratowski, S., Progression through the RNA polymerase II CTD cycle (2009) Mol Cell, 36, pp. 541-546
• Egloff, S., Dienstbier, M., Murphy, S., Updating the RNA polymerase CTD code: adding gene-specific layers (2012) Trends Genet, 28, pp. 333-341
• Heidemann, M., Hintermair, C., Voß, K., Eick, D., Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription (2013) Biochim Biophys Acta, 1829, pp. 55-62
• Hsin, J.-P., Manley, J.L., The RNA polymerase II CTD coordinates transcription and RNA processing (2012) Genes Dev, 26, pp. 2119-2137
• Kim, M., Krogan, N.J., Vasiljeva, L., Rando, O.J., Nedea, E., Greenblatt, J.F., Buratowski, S., The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II (2004) Nature, 432, pp. 517-522
• Egloff, S., O'Reilly, D., Chapman, R.D., Taylor, A., Tanzhaus, K., Pitts, L., Eick, D., Murphy, S., Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression (2007) Science, 318, pp. 1777-1779
• Hsin, J.-P., Sheth, A., Manley, J.L., RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing (2011) Science, 334, pp. 683-686
• Moore, M.J., Proudfoot, N.J., Pre-mRNA processing reaches back to transcription and ahead to translation (2009) Cell, 136, pp. 688-700
• Perales, R., Bentley, D., Cotranscriptionality: the transcription elongation complex as a nexus for nuclear transactions (2009) Mol Cell, 36, pp. 178-191
• Das, R., Yu, J., Zhang, Z., Gygi, M.P., Krainer, A.R., Gygi, S.P., Reed, R., SR proteins function in coupling RNAP II transcription to pre-mRNA splicing (2007) Mol Cell, 26, pp. 867-881
• De la Mata, M., Kornblihtt, A.R., RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20 (2006) Nat Struct Mol Biol, 13, pp. 973-980
• Monsalve, M., Wu, Z., Adelmant, G., Puigserver, P., Fan, M., Spiegelman, B.M., Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 (2000) Mol Cell, 6, pp. 307-316
• Huang, Y., Li, W., Yao, X., Lin, Q.J., Yin, J.W., Liang, Y., Heiner, M., Wang, G., Mediator complex regulates alternative mRNA processing via the MED23 subunit (2012) Mol Cell, 45, pp. 459-469
• De La Mata, M., Alonso, C.R., Kadener, S., Fededa, J.P., Blaustein, M., Pelisch, F., Cramer, P., Kornblihtt, A.R., A slow RNA polymerase II affects alternative splicing in vivo (2003) Mol Cell, 12, pp. 525-532
• Shukla, S., Kavak, E., Gregory, M., Imashimizu, M., Shutinoski, B., Kashlev, M., Oberdoerffer, P., Oberdoerffer, S., CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing (2011) Nature, 479, pp. 74-79
• Amit, M., Donyo, M., Hollander, D., Goren, A., Kim, E., Gelfman, S., Lev-Maor, G., Postolsky, B., Differential GC content between exons and introns establishes distinct strategies of splice-site recognition (2012) Cell Rep, 1, pp. 543-556
• Tilgner, H., Knowles, D.G., Johnson, R., Davis, C.A., Chakrabortty, S., Djebali, S., Curado, J., Guigó, R., Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs (2012) Genome Res, 22, pp. 1616-1625
• Spies, N., Nielsen, C.B., Padgett, R.A., Burge, C.B., Biased chromatin signatures around polyadenylation sites and exons (2009) Mol Cell, 36, pp. 245-254
• Keren-Shaul, H., Lev-Maor, G., Ast, G., Pre-mRNA splicing is a determinant of nucleosome organization (2013) PLoS One, p. 8
• Schwartz, S., Meshorer, E., Ast, G., Chromatin organization marks exon-intron structure (2009) Nat Struct Mol Biol, 16, pp. 990-995
• Huang, H., Yu, S., Liu, H., Sun, X., Nucleosome organization in sequences of alternative events in human genome (2012) BioSystems, 109, pp. 214-219
• Dujardin, G., Lafaille, C., de la Mata, M., Marasco, L.E., Muñoz, M.J., Le Jossic-Corcos, C., Corcos, L., Kornblihtt, A.R., How slow RNA polymerase II elongation favors alternative exon skipping (2014) Mol Cell, 54, pp. 683-690
• Coulter, D.E., Greenleaf, A.L., A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro (1985) J Biol Chem, 260, pp. 13190-13198
• Chen, Y., Chafin, D., Price, D.H., Greenleaf, A.L., Drosophila RNA polymerase II mutants that affect transcription elongation (1996) J Biol Chem, 271, pp. 5993-5999
• Alló, M., Buggiano, V., Fededa, J.P., Petrillo, E., Schor, I., de la Mata, M., Agirre, E., Elela, S.A., Control of alternative splicing through siRNA-mediated transcriptional gene silencing (2009) Nat Struct Mol Biol, 16, pp. 717-724
• Ameyar-Zazoua, M., Rachez, C., Souidi, M., Robin, P., Fritsch, L., Young, R., Morozova, N., Andrau, J.-C., Argonaute proteins couple chromatin silencing to alternative splicing (2012) Nat Struct Mol Biol, 19, pp. 998-1004
• Schor, I.E., Rascovan, N., Pelisch, F., Alló, M., Kornblihtt, A.R., Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing (2009) Proc Natl Acad Sci USA, 106, pp. 4325-4330
• Schor, I.E., Fiszbein, A., Petrillo, E., Kornblihtt, A.R., Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation (2013) EMBO J, 32, pp. 2264-2274
• Luco, R.F., Pan, Q., Tominaga, K., Blencowe, B.J., Pereira-Smith, O.M., Misteli, T., Regulation of alternative splicing by histone modifications (2010) Science, 327, pp. 996-1000
• Luco, R.F., Allo, M., Schor, I.E., Kornblihtt, A.R., Misteli, T., Epigenetics in alternative pre-mRNA splicing (2011) Cell, 144, pp. 16-26
• Gonzalez, I., Munita, R., Agirre, E., Dittmer, T., Gysling, K., Misteli, T., Luco, R.F., A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature (2015) Nat Struct Mol Biol, 5, pp. 370-376
• Zhou, H.-L., Hinman, M.N., Barron, V.A., Geng, C., Zhou, G., Luo, G., Siegel, R.E., Lou, H., Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner (2011) Proc Natl Acad Sci USA, 108, pp. E627-E635
• De Almeida, S.F., Grosso, A.R., Koch, F., Fenouil, R., Carvalho, S., Andrade, J., Levezinho, H., Gut, I., Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36 (2011) Nat Struct Mol Biol, 18, pp. 977-983
• Mathieu, O., Bouché, N., Interplay between chromatin and RNA processing (2014) Curr Opin Plant Biol, 18, pp. 60-65
• Bond, D.M., Baulcombe, D.C., Epigenetic transitions leading to heritable, RNA-mediated de novo silencing in Arabidopsis thaliana (2015) Proc Natl Acad Sci USA, 112, pp. 917-922
• Ausin, I., Greenberg, M.V.C., Li, C.F., Jacobsen, S.E., The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis (2012) Epigenetics, 7, pp. 29-33
• Zhang, C.-J., Zhou, J.-X., Liu, J., Ma, Z.-Y., Zhang, S.-W., Dou, K., Huang, H.-W., Zhu, J.-K., The splicing machinery promotes RNA-directed DNA methylation and transcriptional silencing in Arabidopsis (2013) EMBO J, 32, pp. 1128-1140
• Henriques, R., Mas, P., Chromatin remodeling and alternative splicing: pre- and post-transcriptional regulation of the Arabidopsis circadian clock (2013) Semin Cell Dev Biol, 24, pp. 399-406
• Sanchez, S.E., Petrillo, E., Beckwith, E.J., Zhang, X., Rugnone, M.L., Hernando, C.E., Cuevas, J.C., Simpson, C.G., A methyl transferase links the circadian clock to the regulation of alternative splicing (2010) Nature, 468, pp. 112-116
• Cocquerelle, C., Mascrez, B., Hétuin, D., Bailleul, B., Mis-splicing yields circular RNA molecules (1993) FASEB J, 7, pp. 155-160
• Wilusz, J., Circular RNA and splicing: skip happens (2015) J Mol Biol, 427, pp. 2411-2413
• Mongelard, F., Labrador, M., Baxter, E.M., Gerasimova, T.I., Corces, V.G., Trans-splicing as a novel mechanism to explain interallelic complementation in Drosophila (2002) Genetics, 160, pp. 1481-1487
• Ullu, E., Matthews, K.R., Tschudi, C., Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts (1993) Mol Cell Biol, 13 (1), pp. 720-725
• Casado-Vela, J., Lacal, J.C., Elortza, F., Protein chimerism: novel source of protein diversity in humans adds complexity to bottom-up proteomics (2013) Proteomics, 13, pp. 5-11
• Berget, S.M., Sharp, P., A spliced sequence at the 5'-terminus of adenovirus late mRNA (1977) Brookhaven Symp Biol, 74, pp. 332-344
• Chow, L.T., Gelinas, R.E., Broker, T.R., Roberts, R.J., An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA (1977) Cell, 2, pp. 1-8

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