Abstract:
The natural compound dendocarbin A, C15H22O3, is a sesquiterpene lactone isolated for the first time from Drimys winteri for var chilensis. The compound crystallizes in the orthorhombic space group P212121 and its X-ray crystal structure confirmed the S/R character of the chiral centres at C-5/C-10 and C-9/C-11, respectively. The α-OH group at C-11 was found to be involved in intermolecular hydrogen bonding, defining chains along the <100> 21 screw axis. © 2014 International Union of Crystallography.
Registro:
Documento: |
Artículo
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Título: | Dendocarbin A: A sesquiterpene lactone from Drimys winteri |
Autor: | Paz Robles, C.; Burgos, V.; Suarez, S.; Baggio, R. |
Filiación: | Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería, Universidad de la Frontera, Temuco, Chile Departamento de Qumica Inorgnica Analtica y Qumica, Fsica/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina Gerencia de Investigación y Aplicaciones, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica, Buenos Aires, Argentina
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Palabras clave: | crystal structure; cytotoxic activity; dendocarbin A; Drimys winteri; natural product; natural sesquiterpene lactone; Cytotoxicity; Esters; Hydrogen bonds; Cytotoxic activities; dendocarbin A; Drimys winteri; Natural products; Sesquiterpene lactones; Crystal structure; Drimys winteri; dendocarbin A; sesquiterpene; chemical structure; chemistry; Drimys; isolation and purification; metabolism; synthesis; X ray crystallography; Crystallography, X-Ray; Drimys; Molecular Structure; Sesquiterpenes |
Año: | 2014
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Volumen: | 70
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Página de inicio: | 1007
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Página de fin: | 1010
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DOI: |
http://dx.doi.org/10.1107/S205322961402155X |
Título revista: | Acta Crystallographica Section C: Structural Chemistry
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Título revista abreviado: | Acta crystallogr., C Struct. Chem.
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ISSN: | 20532296
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CODEN: | ACSCG
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CAS: | dendocarbin A; Sesquiterpenes
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20532296_v70_n_p1007_PazRobles |
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Citas:
---------- APA ----------
Paz Robles, C., Burgos, V., Suarez, S. & Baggio, R.
(2014)
. Dendocarbin A: A sesquiterpene lactone from Drimys winteri. Acta Crystallographica Section C: Structural Chemistry, 70, 1007-1010.
http://dx.doi.org/10.1107/S205322961402155X---------- CHICAGO ----------
Paz Robles, C., Burgos, V., Suarez, S., Baggio, R.
"Dendocarbin A: A sesquiterpene lactone from Drimys winteri"
. Acta Crystallographica Section C: Structural Chemistry 70
(2014) : 1007-1010.
http://dx.doi.org/10.1107/S205322961402155X---------- MLA ----------
Paz Robles, C., Burgos, V., Suarez, S., Baggio, R.
"Dendocarbin A: A sesquiterpene lactone from Drimys winteri"
. Acta Crystallographica Section C: Structural Chemistry, vol. 70, 2014, pp. 1007-1010.
http://dx.doi.org/10.1107/S205322961402155X---------- VANCOUVER ----------
Paz Robles, C., Burgos, V., Suarez, S., Baggio, R. Dendocarbin A: A sesquiterpene lactone from Drimys winteri. Acta crystallogr., C Struct. Chem. 2014;70:1007-1010.
http://dx.doi.org/10.1107/S205322961402155X