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Abstract:

In locusts, two lobula giant movement detector neurons (LGMDs) act as looming object detectors. Their reproducible responses to looming and their ethological significance makes them models for single neuron computation. But there is no comprehensive picture of the neurons that connect directly to each LGMD. We used high-through-put serial block-face scanning-electron-microscopy to reconstruct the network of input-synapses onto the LGMDs over spatial scales ranging from single synapses and small circuits, up to dendritic branches and total excitatory input. Reconstructions reveal that many trans-medullary-afferents (TmAs) connect the eye with each LGMD, one TmA per facet per LGMD. But when a TmA synapses with an LGMD it also connects laterally with another TmA. These inter-TmA synapses are always reciprocal. Total excitatory input to the LGMD 1 and 2 comes from 131,000 and 186,000 synapses reaching densities of 3.1 and 2.6 synapses per μm 2 respectively. We explored the computational consequences of reciprocal synapses between each TmA and 6 others from neighbouring columns. Since any lateral interactions between LGMD inputs have always been inhibitory we may assume these reciprocal lateral connections are most likely inhibitory. Such reciprocal inhibitory synapses increased the LGMD's selectivity for looming over passing objects, particularly at the beginning of object approach. © The Author(s) 2016.

Registro:

Documento: Artículo
Título:Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
Autor:Rind, F.C.; Wernitznig, S.; Pölt, P.; Zankel, A.; Gütl, D.; Sztarker, J.; Leitinger, G.
Filiación:Institute of Neuroscience, Centre for Behaviour and Evolution, Newcastle University, Newcastle upon Tyne, NE1 7RU, United Kingdom
Institute of Cell Biology, Histology and Embryology/Research Unit Electron Microscopic Techniques, Graz, 8010, Austria
Institute for Electron Microscopy and Nanoanalysis/NAWI Graz, Graz University of Technology, Graz, 8010, Austria
Centre for Electron Microscopy, Graz, 8010, Austria
Departamento de Fisiologia, Biologia Molecular y Celular/FCEN, Universidad de Buenos Aires/IFIBYNE-CONICET, Buenos Aires, 1428, Argentina
BioTechMed-Graz, Graz, 8010, Austria
Año:2016
Volumen:6
DOI: http://dx.doi.org/10.1038/srep35525
Título revista:Scientific Reports
Título revista abreviado:Sci. Rep.
ISSN:20452322
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20452322_v6_n_p_Rind

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Citas:

---------- APA ----------
Rind, F.C., Wernitznig, S., Pölt, P., Zankel, A., Gütl, D., Sztarker, J. & Leitinger, G. (2016) . Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects. Scientific Reports, 6.
http://dx.doi.org/10.1038/srep35525
---------- CHICAGO ----------
Rind, F.C., Wernitznig, S., Pölt, P., Zankel, A., Gütl, D., Sztarker, J., et al. "Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects" . Scientific Reports 6 (2016).
http://dx.doi.org/10.1038/srep35525
---------- MLA ----------
Rind, F.C., Wernitznig, S., Pölt, P., Zankel, A., Gütl, D., Sztarker, J., et al. "Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects" . Scientific Reports, vol. 6, 2016.
http://dx.doi.org/10.1038/srep35525
---------- VANCOUVER ----------
Rind, F.C., Wernitznig, S., Pölt, P., Zankel, A., Gütl, D., Sztarker, J., et al. Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects. Sci. Rep. 2016;6.
http://dx.doi.org/10.1038/srep35525