Artículo

Urbano, F.J.; Bisagno, V.; González, B.; Rivero-Echeto, M.C.; MuñIz, J.A.; Luster, B.; D’Onofrio, S.; Mahaffey, S.; Garcia-Rill, E. "Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse" (2015) Sleep Science. 8(3):162-168
Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

This review describes the interactions between the pedunculopontine nucleus (PPN), the ventral tegmental area (VTA), and the thalamocortical system. Experiments using mod­ulators of cholinergic receptors in the PPN clarified its role on psychostimulant-induced locomotion. PPN activation was found to be involved in the animal’s voluntary search for psychostimulants. Every PPN neuron is known to generate gamma band oscillations. Voltage-gated calcium channels are key elements in the generation and maintenance of gamma band activity of PPN neurons. Calcium channels are also key elements mediating psychostimulant-induced alterations in the thalamic targets of PPN output. Thus, the PPN is a key substrate for maintaining arousal and REM sleep, but also in modulating psychostimulant self-administration. © 2015 Brazilian Association of Sleep.

Registro:

Documento: Artículo
Título:Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse
Autor:Urbano, F.J.; Bisagno, V.; González, B.; Rivero-Echeto, M.C.; MuñIz, J.A.; Luster, B.; D’Onofrio, S.; Mahaffey, S.; Garcia-Rill, E.
Filiación:Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, AR, United States
Ifibyne-conicet, Ininfa-conicet, University of Buenos Aires, Argentina
Palabras clave:Amphetamine; Cocaine; Dopamine; Nicotine; P/Q-type calciumchannels T-type calciumchannels; calcium channel; cocaine; nicotine; psychostimulant agent; behavior; human; locomotion; membrane potential; pedunculopontine tegmental nucleus; physiology; Review; sleep arousal disorder; sleep deprivation
Año:2015
Volumen:8
Número:3
Página de inicio:162
Página de fin:168
DOI: http://dx.doi.org/10.1016/j.slsci.2015.09.004
Título revista:Sleep Science
Título revista abreviado:Sleep Sci.
ISSN:19840659
CAS:cocaine, 50-36-2, 53-21-4, 5937-29-1; nicotine, 54-11-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19840659_v8_n3_p162_Urbano

Referencias:

  • Garcia-Rill, E., The RAS and Drug Abuse in Reticular Activating System in Waking and the Reticular Activating System Health and Disease, pp. 277-290. , Academic Press, Elsevier
  • Hallanger, A.E., Levey, A.I., Lee, H.J., Rye, D.B., Wainer, B.H., The origins of cholinergic and other subcortical afferents to the thalamus in the rat (1987) J. Comp. Neurol, 262, pp. 105-124
  • Steriade, M., Pare, D., Parent, A., Smith, Y., Projections of cholinergic and noncholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey (1988) Neuroscience, 25, pp. 47-67
  • Steriade, M., McCarley, R.W., (2005) Brain Control of Wakefulness and Sleep, , New York: Springer
  • Steriade, M., Datta, S., Pare, D., Oakson, G., Curro Dossi, R.C., Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems (1990) J. Neurosci, 10, pp. 2541-2559
  • Steriade, M., Jones, E.G., McCormick, D.A., (1997) Thalamus, Volume I: Organization and Function, , Amsterdam: Elsevier
  • Deschenes, M., Madariaga-Domich, A., Steriade, M., Dendroden- dritic synapses in cat reticularis thalami nucleus, a structural basis for thalamic spindle synchronization (1985) Brain Res, 334, pp. 169-171
  • Landisman, C.E., Long, M.A., Beierlein, M., Electrical synapses in the thalamic reticular nucleus (2002) J. Neurosci, 22, pp. 1002-1009
  • Ben-Ari, Y., Dingledine, R., Kanazawa, I., Kelly, J.S., Inhibitory effects of acetylcholine on neurones in the feline nucleus reticularis thalami (1976) J. Physiol. (Lond.), 261, pp. 647-671
  • Bista, P., Meuth, S.G., Kanyshkova, T., Cerina, M., Pawlowsk, M., Ehling, P., Landgraf, P., Budde, T., Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons (2012) Pflugers Arch, 463, pp. 89-102
  • Llinás, R.R., Ribary, U., Jeanmonod, D., Kronberg, E., Mitra PP Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalo- graphy (1999) Proc. Natl. Acad. Sci. USA, 96, pp. 15222-15227
  • Llinás, R.R., Urbano, F.J., Leznik, E., Ramirez, R.R., Van Marle, H.J., Rhythmic and dysrhythmic thalamocortical dynamics: GABA systems and the edge effect (2005) Trends Neurosci, 28, pp. 325-333
  • Llinas, R.R., Choi, S., Urbano, F.J., Hee-Sup S. Y-Band deficiency and abnormal thalamocortical activity in P/Q-type channel mutant mice (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 17819-17824
  • Di Chiara, G., Imperato, A., Drugs abused by humans prefer­entially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl (1988) Acad. Sci. USA, 85, pp. 5274-5278
  • Maskos, U., The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: Relevance to the drugs of abuse and pathology (2008) Br. J. Pharmacol, 1, pp. 438-445
  • Floresco, S.B., West, A.R., Ash, B., Moore, H., Grace AA. Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission (2003) Nat. Neu- Rosci, 6, pp. 968-973
  • Good, C.H., Lupica, C.R., Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro (2009) J. Physiol. (Lond.), 587, pp. 1233-1247
  • Lammel, S., Lim, B.K., Ran, C., Huang, K.W., Betley, M.J., Tye, K.M., Deisseroth, K., Malenka, R.C., Input-specific control of reward and aversion in the ventral tegmental area (2012) Nature, 491, pp. 212-217
  • Circuits, K.G., Drugs, and drug addiction. Adv (1998) Pharmacol, 42, pp. 978-982
  • White, F.J., Kalivas, P.W., Neuroadaptations involved in amphetamine and cocaine addiction (1998) Drug Alcohol Depend, 51, pp. 141-153
  • Wise, R.A., Drug-activation of brain reward pathways (1998) Drug Alcohol Depend, 51, pp. 13-22
  • Luster, B., D’Onofrio, S., Urbano, F., Garcia-Rill, E., High-threshold Ca2+ channels behind gamma band activity in the pedun- culopontine nucleus (PPN) (2015) Physiol. Rep, 3
  • Kezunovic, N., Hyde, J., Goitia, B., Bisagno, V., Urbano, F.J., Garcia- Rill, E., Muscarinic modulation of high frequency oscillations in pedunculopontine neurons (2013) Front. Neurol, 4 (176), pp. 1-13
  • Hillman, D., Chen, S., Aung, T.T., Cherksey, B., Sugimori, M., Llinas, R.R., Localization of P-type calcium channels in the central nervous system (1991) Proc. Natl. Acad. Sci. USA, 88, pp. 7076-7080
  • Uchitel, O.D., Protti, D.A., Sanchez, V., Cherkesey, B.D., Sugimori, M., Llinas, R.R., -type voltage dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses (1992) Proc. Natl. Acad. Sci. USA, 89, pp. 3330-3333
  • Kezunovic, N., Urbano, F.J., Simon, C., Hyde, J., Smith, K., Garcia-Rill, E., Mechanism behind gamma band activity in pedunculo- pontine nucleus (PPN) (2011) Eur. J. Neurosci, 34, pp. 404-415
  • Garcia-Rill, E., Kezunovic, N., Hyde, J., Beck, P., Urbano, F.J., . Coherence and frequency in the reticular activating system (RAS) (2013) Sleep Med. Rev, 17, pp. 227-238
  • Urbano, F.J., Kezunovic, N., Hyde, J., Simon, C., Beck, P., Garcia-Rill, E., Gamma band activity in the reticular activating system (RAS) (2012) Front. Neurol. Sleep Chronobiol, 3 (6), pp. 1-16
  • Pedroarena, C., Llinas, R.R., Dendritic calcium conductances generate high-frequency oscillation in thalamocortical neurons (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 724-728
  • Seiden, L.S., Sabol, K.E., Ricaurte, G.A., Amphetamine: Effects on catecholamine systems and behavior (1993) Annu. Rev. Pharmacol. Toxicol, 32, pp. 639-677
  • Sulzer, D., Chen, T.K., Lau, Y.Y., Kristensen, H., Rayport, S., Ewing A. Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport (1995) J. Neu- Rosci, 15, pp. 4102-4108
  • Mlewski, E.C., Krapacher, F.A., Ferreras, S., Paglini G. Transient enhanced expression of Cdk5 activator p25 after acute and chronic d-amphetamine administration (2008) Ann. N. Y. Acad. Sci, 1139, pp. 89-102
  • Singer, B.F., Neugebauer, N.M., Forneris, J., Rodvelt, K.R., Li, D., Bubula, N., Vezina, P., Locomotor conditioning byamphetamine requires cyclin-dependent kinase 5 signaling in the nucleus accumbens (2014) Neuropharmacology, 85, pp. 243-252
  • Tomizawa, K., Ohta, J., Matsushita, M., Moriwaki, A., Li, S., Takei, K., Matsui, H., Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity (2002) J. Neurosci, 22, pp. 2590-2597
  • Karila, L., Weinstein, A., Aubin, H.J., Benyamina, A., Reynaud, M., Batki, S.L., Pharmacological approaches to methamphetamine dependence: A focused review (2010) Br. J. Clin. Pharmacol, 69, pp. 578-592
  • González, B., Rivero-Echeto, C., Muniz, J.A., Cadet, J.L., Garcia-Rill, E., Urbano, F.J., Bisagno, V., Methamphetamine blunts Ca2+ cur­rents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial pre- frontal cortex (2015) Addict. Biol, , in press
  • Pierre, P.J., Vezina, P., Predisposition to self-administer amphetamine: The contribution of response to novelty and prior exposure to the drug (1997) Psychopharmacology, 129, pp. 277-284
  • Saito, L.P., Fukushiro, D.F., Hollais, A.W., Mari-Kawamoto, E., Costa, J.M., Berro, L.F., Aramini, T.C., Frussa-Filho, R., Acute total sleep deprivation potentiates amphetamine-induced locomotor-stimulant effects and behavioral sensitization in mice (2014) Pharmacol. Biochem. Behav, 117, pp. 7-16
  • Alderson, H.L., Faulconbridge, L.F., Gregory, L.P., Latimer, M.P., Winn, P., Behavioural sensitisation to repeated d-amphetamine: Effects of excitotoxic lesions of the pedunculopontine tegmental nucleus (2003) Neuroscience, 118 (2), pp. 311-315
  • Lee, R.S., Steffensen, S.C., Henriksen, S.J., Discharge profiles of ventral tegmental area GABA neurons during movement, anesthesia, and the sleep-wake cycle (2001) J. Neurosci, 21, pp. 1757-1766
  • Bechara, A., Van Der Kooy, D., The tegmental pedunculopontine nucleus: A brainstem output of the limbic system critical for the conditioned place preferences produced by morphine and amphetamine (1989) J. Neurosci, 9, pp. 3400-3409
  • Shannon, H.E., Peters, S.C., A comparison of the effects of cholinergic and dopaminergic agents on scopolamine- induced hyperactivity in mice (1990) J. Pharmacol. Exp. Ther, 255, pp. 549-553
  • Hagan, J.J., Tonnaer, J., Rijk, H., Broekkamp, C., Van Delft, A.M.L., Facilitation of amphetamine-induced rotation by muscarinic antagonists is correlated with M2 receptor affinity (1987) Brain Res, 410, pp. 69-73
  • Asanuma, C., Distribution of neuromodulatory inputs in the reticular and dorsal thalami nuclei (1997) Experimental and Clinical Aspects, 2, pp. 93-154. , Steriade M, Jones EG, McCormick DA, Thalamus, Amsterdam: Elsevier
  • Wilson, M.C., Bedford, J.A., Buelke, J., Kibbe, A.H., Acute pharmacological activity of intravenous cocaine in the rhesus monkey Psychopharmacol (1976) Commun, 2, pp. 251-261
  • Wise, R.A., Bozarth, M.A., A psychomotor stimulant theory of addiction (1987) Psychol. Rev, 94, pp. 469-492
  • Ross, S.B., Renyi, A.L., Inhibition of the uptake of tritiated 5- hydroxytryptamine in brain tissue (1969) Eur. J. Pharmacol, 7, pp. 270-277
  • Grimm, J.W., See, R.E., Cocaine self-administration in ovariec- tomized rats is predicted by response to novelty, attenuated by 17-b estradiol, and associated with abnormal vaginal cytology (1997) Physiol. Behav, 61, pp. 755-761
  • Schmidt, H.D., Famous, K.R., Pierce, R.C., The limbic circuitry underlying cocaine seeking encompasses the PPTg/LDT (2009) Eur. J. Neurosci, 30, pp. 1358-1369
  • Steidl, S., Wang, H., Wise, R.A., Lesions of cholinergic peduncu- lopontine tegmental nucleus neurons fail to affect cocaine or heroin self-administration or conditioned place preference in rats (2014) Plos One, 9
  • Goitia, B., Raineri, M., Gonzalez, L.E., Rozas, J.L., Garcia-Rill, E., Bisagno, V., Urbano FJ. Differential effects of methylphenidate and cocaine on GABA transmission in sensory thalamic nuclei (2013) J. Neurochem, 124, pp. 602-612
  • Urbano, F.J., Bisagno, V., Wikinski, S.I., Uchitel, O.D., Llin^s RR. Cocaine acute "binge" administration results in altered thalamocortical interactions in mice. Biol (2009) Psychiatry, 66 (8), pp. 769-776
  • Bisagno, V., Raineri, M., Peskin, V., Wikinski, S.I., Uchitel, O.D., Llinás, R.R., Urbano, F.J., Effects of T-type calcium channel blockers on cocaine-induced hyperlocomotion and thalamocortical GABAergic abnormalities in mice (2010) Psychopharmacology (Berl.), 212, pp. 205-214
  • Berro, L.F., Santos, R., Hollais, A.W., Wuo-Silva, R., Fukushiro, D.F., Mari-Kawamoto, E., Costa, J.M., Frussa-Filho, R., Acute total sleep deprivation potentiates cocaine-induced hyperlocomotion in mice. Neurosci (2014) Lett, 579, pp. 130-133
  • Raineri, M., Peskin, V., Goitia, B., Taravini, I.R., Giorgeri, S., Urbano, F.J., Bisagno, V., Attenuated methamphetamine induced neu­rotoxicity by modafinil administration in mice (2011) Synapse, 65 (10), pp. 1087-1098
  • Raineri, M., Gonzalez, B., Goitia, B., Garcia-Rill, E., Krasnova, I.N., Cadet, J.L., Urbano, F.J., Bisagno, V., Modafinil abrogates methamphetamine-induced neuroinflammation and apop- totic effects in the mouse striatum (2012) Plos One, 7 (10)
  • Raineri, M., Gonzalez, B., Rivero-Echeto, C., Muniz, J.A., Gutierrez, M.L., Ghanem, C.I., Cadet, J.L., Bisagno, V., Differential effects of environment-induced changes in body temperature on modafinil’s actions against methamphetamine-induced striatal toxicity in mice (2014) Neu- Rotox. Res, 27 (1), pp. 71-83
  • Garcia-Rill, E., Heister, D.S., Ye, M., Charlesworth, A., Hayar, A., Electrical coupling: Novel mechanism for sleep-wake control (2007) Sleep, 30, pp. 1405-1414
  • Urbano, F.J., Leznik, E., Llinas, R.R., Modafinil enhances thalamocortical activity by increasing neuronal electrotonic coupling (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 12554-12559
  • Gonzalez, B., Raineri, M., Cadet, J.L., Garcia-Rill, E., Urbano, F.J., Bisagno, V., Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice (2014) Neuropharmacology, 87, pp. 188-197
  • Edgar, C.J., Pace-Schott, E.F., Wesnes, K.A., Approaches to measuring the effects of wake-promoting drugs: A focus on cognitive function. Hum (2009) Psychopharmacol, 24 (5), pp. 371-389
  • Jiang, X., Lautermilch, N.J., Watari, H., Westenbroek, R.E., Scheuer, T., Catterall, W.A., Modulation of Cav2.1 channels by Ca+/ calmodulin-dependent kinase II bound to the C-terminal domain (2008) Proc. Nat. Acad. Sci. USA, 105, pp. 341-346
  • Good, C.H., Bay, K.D., Buchanan, R., Skinner, R.D., Garcia-Rill, E., Muscarinic and nicotinic responses in the developing ped- unculopontine nucleus (PPN) (2007) Brain Res, 1129, pp. 147-155
  • Benowitz, N.L., Pharmacology of nicotine: Addiction and therapeutics (1996) Ann. Rev. Pharmacol. Toxicol, 36, pp. 597-613
  • Simosky, J.K., Stevens, K.E., Freedman, R., Nicotinic agonists and psychosis. Curr. Drug Targets— CNS Neurol (2002) Disord, 1, pp. 177-190
  • Luck, W., Nau, H., Hansen, R., Steldinger, R., Extent of nicotine and cotinine transfer to the human fetus, placenta and amniotic fluid of smoking mothers. Dev. Pharmacol (1985) Ther, 8, pp. 384-395
  • Eskanazi, B., Prehn, A.W., Cristianson, R.E., Passive and active maternal smoking as measured by serum cotinine: The effect on birthweight (1995) Am. J. Public Health, 85, pp. 395-398
  • Kline, J., Stein, Z.A., Susser, M., Warburton, D., Smoking: A risk factor for spontaneous abortion. New Engl (1997) J. Med, 297, pp. 793-796
  • Bulterys, M., High incidence of sudden infant death syndrome among northern Indians and Alaska natives compared with southwestern Indians: Possible role of smoking (1990) J. Com. Health, 15, pp. 185-194
  • Weissman, M.M., Warner, V., Wickramaratne, P.J., Kandel, D.B., Maternal smoking during pregnancy and psychopathology in offspring followed to adulthood (1999) J. Am. Acad. Child Adolesc. Psychiatry, 38, pp. 892-899
  • Fried, P.A., O’Connell, C.M., Watkinson, B., 60 and 72-month follow-up of children prenatally exposed to marijuana, cigarettes and alcohol: Cognitive and language assessments (1992) J. Dev. Behav. Pediatr, 13, pp. 383-391
  • Milberger, S., Biederman, J., Farraone, S.V., Chen, L., Jones, J., ADHD is associated with early initiation of cigarette smoking in children and adolescents (1997) J. Am. Acad. Child Adolesc. Psychiatry, 36, pp. 37-44
  • Wasserman, G.A., Liu, X., Pine, D.S., Graziano, J.H., Contribution of maternal smoking during pregnancy and lead exposure to early child behavior problems (2001) Neurotoxicol. Teratol, 23 (1), pp. 13-21
  • Fergusson, D.M., Woodward, L.J., Horwood, L.J., Maternal smoking during pregnancy and psychiatric adjustment in late adolescence (1998) Arch. Gen. Psychiat, 55, pp. 721-727
  • Wakschlag, L.S., Lahey, B.B., Loeber, R., Green, S.M., Gordon, R.A., Leventhal, B.L., Maternal smoking during pregnancy and the risk of conduct disorders in boys (1997) Arch. Gen. Psychiatry, 54, pp. 670-676
  • Rasanen, P., Hakko, H., Isohanni, M., Hodgins, S., Jarvelin, M.R., Tiihonen, J., Maternal smoking during pregnancy and risk of criminal behavior among adult male offspring in the Northern Finland 1966 Birth Cohort (1966) Am. J. Psychiatry, 156, pp. 857-862
  • Levin, E.D., Briggs, S.J., Christopher, N.C., Rose, J.E., Prenatal nicotine exposure and cognitive performance in rats (1993) Neurotoxicol. Teratol, 15, pp. 251-260
  • Sorenson, C.A., Raskin, L.A., Suh, Y., The effects of prenatal nicotine on radial-arm maze performance in rats (1991) Pharma-Icol. Biochem. Behav, 40, pp. 991-993
  • Martin, J.C., Becker, R.F.T., The effects of maternal nicotine absorption or hypoxic episodes upon appetitive behavior of rat offspring (1971) Dev. Psychobiol, 4, pp. 133-147
  • Garcia-Rill, E., Buchanan, R., McKeon, K., Skinner, R.D., Wallace, T., Smoking during pregnancy: Postnatal effects on arousal andi attentional brain systems (2007) Neurotox, 28, pp. 915-923
  • Cadet, J.L., Bisagno, V., Milroy, C.M., Neuropathology of substance r use disorders (2014) Acta Neuropathol, 127 (1), pp. 91-107
  • Hasler, B.P., Soehner, A.M., Clark, D.B., Circadian rhythms and risk for substance use disorders in adolescence (2014) Curr. Opin. Psychiatry, 27 (6), pp. 460-466
  • Brower, K.J., Perron, B.E., Sleep disturbances as a universal risk factor for relapse in addictions to psychoactive substances (2010) Med. Hypotheses, 74, pp. 928-933

Citas:

---------- APA ----------
Urbano, F.J., Bisagno, V., González, B., Rivero-Echeto, M.C., MuñIz, J.A., Luster, B., D’Onofrio, S.,..., Garcia-Rill, E. (2015) . Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse. Sleep Science, 8(3), 162-168.
http://dx.doi.org/10.1016/j.slsci.2015.09.004
---------- CHICAGO ----------
Urbano, F.J., Bisagno, V., González, B., Rivero-Echeto, M.C., MuñIz, J.A., Luster, B., et al. "Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse" . Sleep Science 8, no. 3 (2015) : 162-168.
http://dx.doi.org/10.1016/j.slsci.2015.09.004
---------- MLA ----------
Urbano, F.J., Bisagno, V., González, B., Rivero-Echeto, M.C., MuñIz, J.A., Luster, B., et al. "Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse" . Sleep Science, vol. 8, no. 3, 2015, pp. 162-168.
http://dx.doi.org/10.1016/j.slsci.2015.09.004
---------- VANCOUVER ----------
Urbano, F.J., Bisagno, V., González, B., Rivero-Echeto, M.C., MuñIz, J.A., Luster, B., et al. Pedunculopontine arousal system(Ft physiology—effects of psychostimulant abuse. Sleep Sci. 2015;8(3):162-168.
http://dx.doi.org/10.1016/j.slsci.2015.09.004