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Abstract:

In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosensors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter's expression or both. But some other inventors exploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most relevant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors. © 2010 Bentham Science Publishers Ltd.

Registro:

Documento: Artículo
Título:Whole-cell biosensors: Research and patents
Autor:Fernández, M.R.; Bernik, D.L.
Filiación:Instituto De Química Física De Los Materiales, Medio Ambiente Y Energía (INQUIMAE-CONICET), School of Sciences, University of Buenos Aires, Argentina
Palabras clave:Bioreporters; Chemical sensors; Integrated sensors; Living sensors; Whole-cell biosensors; Whole-cell sensors; Bioreporters; Integrated sensors; Living sensors; Whole-cell biosensors; Whole-cell sensors; Cells; Chemical analysis; Chemical sensors; Cytology; Detectors; Genetic engineering; Machinery; Nucleic acids; Patents and inventions; Biosensors
Año:2010
Volumen:3
Número:3
Página de inicio:138
Página de fin:146
Título revista:Recent Patents on Biomedical Engineering
Título revista abreviado:Recent Pat. Biomed. Eng.
ISSN:18747647
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18747647_v3_n3_p138_Fernandez

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Citas:

---------- APA ----------
Fernández, M.R. & Bernik, D.L. (2010) . Whole-cell biosensors: Research and patents. Recent Patents on Biomedical Engineering, 3(3), 138-146.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18747647_v3_n3_p138_Fernandez [ ]
---------- CHICAGO ----------
Fernández, M.R., Bernik, D.L. "Whole-cell biosensors: Research and patents" . Recent Patents on Biomedical Engineering 3, no. 3 (2010) : 138-146.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18747647_v3_n3_p138_Fernandez [ ]
---------- MLA ----------
Fernández, M.R., Bernik, D.L. "Whole-cell biosensors: Research and patents" . Recent Patents on Biomedical Engineering, vol. 3, no. 3, 2010, pp. 138-146.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18747647_v3_n3_p138_Fernandez [ ]
---------- VANCOUVER ----------
Fernández, M.R., Bernik, D.L. Whole-cell biosensors: Research and patents. Recent Pat. Biomed. Eng. 2010;3(3):138-146.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18747647_v3_n3_p138_Fernandez [ ]