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Abstract:

The possible genetic correlation between longevity and knockdown resistance to high temperature (KRHT) was tested in reciprocal backcrosses between nearly-homozygous lines of D. melanogaster. These baselines differ dramatically for KRHT. Because nearly-homozygous lines were used, reciprocal backcrosses were informative to test for dominant versus additive genetic associations between the traits. The line of high KRHT was longer lived than the low KRHT line. The correlation between longevity and KRHT was dependent on the backcross (BC). When a BC was set up with males from the low KRHT line, the most KRHT resistant individuals were in turn the longest-lived flies. However, this was not found in the reciprocal backcross, indicating dominance. Alleles that confer increased KRHT are dominant in the correlation between longevity and KRHT. The between-line variation in the traits studied is consistent with the hypothesis that stress-resistant genotypes correspond to long-lived individuals. © 2009 Bentham Science Publishers Ltd.

Registro:

Documento: Artículo
Título:Dominance variation in the correlation between longevity and heatstress resistance in drosophila melanogaster
Autor:Defays, R.; Fernández, M.J.G.; Norry, F.M.
Filiación:Departamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, (C-1428-EHA) Buenos Aires, Argentina
Museo Argentino de Ciencias Naturales Bernardino Rivadavia, Avenida Angel Gallardo 470. (C1405DJR) Buenos Aires, Argentina
Palabras clave:Dominance; Heat knockdown resistance; Heat sensitivity; Senescence; article; correlation analysis; Drosophila melanogaster; genetic correlation; genetic trait; genetic variability; heat sensitivity; heat stress; heat tolerance; homozygosity; nonhuman; priority journal; senescence; adaptation; animal; cross breeding; dominant gene; female; genetics; heat shock response; homozygote; inheritance; longevity; male; phenotype; population density; time; Adaptation, Physiological; Animals; Crosses, Genetic; Drosophila melanogaster; Female; Genes, Dominant; Heat-Shock Response; Homozygote; Inheritance Patterns; Longevity; Male; Phenotype; Population Density; Time Factors
Año:2009
Volumen:2
Número:2
Página de inicio:103
Página de fin:108
DOI: http://dx.doi.org/10.2174/1874609810902020103
Título revista:Current Aging Science
Título revista abreviado:Curr. Aging Sci.
ISSN:18746098
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18746098_v2_n2_p103_Defays

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Citas:

---------- APA ----------
Defays, R., Fernández, M.J.G. & Norry, F.M. (2009) . Dominance variation in the correlation between longevity and heatstress resistance in drosophila melanogaster. Current Aging Science, 2(2), 103-108.
http://dx.doi.org/10.2174/1874609810902020103
---------- CHICAGO ----------
Defays, R., Fernández, M.J.G., Norry, F.M. "Dominance variation in the correlation between longevity and heatstress resistance in drosophila melanogaster" . Current Aging Science 2, no. 2 (2009) : 103-108.
http://dx.doi.org/10.2174/1874609810902020103
---------- MLA ----------
Defays, R., Fernández, M.J.G., Norry, F.M. "Dominance variation in the correlation between longevity and heatstress resistance in drosophila melanogaster" . Current Aging Science, vol. 2, no. 2, 2009, pp. 103-108.
http://dx.doi.org/10.2174/1874609810902020103
---------- VANCOUVER ----------
Defays, R., Fernández, M.J.G., Norry, F.M. Dominance variation in the correlation between longevity and heatstress resistance in drosophila melanogaster. Curr. Aging Sci. 2009;2(2):103-108.
http://dx.doi.org/10.2174/1874609810902020103