Registro:

Referencias:

• Brinton, R.D., Thompson, R.F., Foy, M.R., Baudry, M., Wang, J., Finch, C.E., Morgan, T.E., Nilsen, J., Progesterone receptors: form and function in brain (2008) Front Neuroendocrinol, 29, pp. 313-339
• De Nicola, A.F., Labombarda, F., Deniselle, M.C., Gonzalez, S.L., Garay, L., Meyer, M., Gargiulo, G., Schumacher, M., Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration (2009) Front Neuroendocrinol, 30, pp. 173-187
• Schumacher, M., Guennoun, R., Stein, D.G., De Nicola, A.F., Progesterone: therapeutic opportunities for neuroprotection and myelin repair (2007) Pharmacol Ther, 116, pp. 77-106
• Stein, D.G., Progesterone exerts neuroprotective effects after brain injury (2008) Brain Res Rev, 57, pp. 386-397
• Baulieu, E.E., Neurosteroids: of the nervous system., by the nervous system., for the nervous system (1997) Recent Prog Horm Res, 52, pp. 1-32
• Aupperlee, M.D., Drolet, A.A., Durairaj, S., Wang, W., Schwartz, R.C., Haslam, S.Z., Strain-specific differences in the mechanisms of progesterone regulation of murine mammary gland development (2009) Endocrinology, 150, pp. 1485-1494
• Labombarda, F., Guennoun, R., Gonzalez, S., Roig, P., Lima, A., Schumacher, M., De Nicola, A.F., Immunocytochemical evidence for a progesterone receptor in neurons and glial cells of the rat spinal cord (2000) Neurosci Lett, 288, pp. 29-32
• Waters, E.M., Torres-Reveron, A., McEwen, B.S., Milner, T.A., Ultrastructural localization of extranuclear progestin receptors in the rat hippocampal formation (2008) J Comp Neurol, 511, pp. 34-46
• Majewska, M.D., Harrison, N.L., Schwartz, R.D., Barker, J.L., Paul, S.M., Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor (1986) Science, 232, pp. 1004-1007
• Zhu, Y., Hanna, R.N., Schaaf, M.J., Spaink, H.P., Thomas, P., Candidates for membrane progestin receptors-past approaches and future challenges (2008) Comp Biochem Physiol C Toxicol Pharmacol, 148, pp. 381-389
• Labombarda, F., Meffre, D., Delespierre, B., Krivokapic-Blondiaux, S., Chastre, A., Thomas, P., Pang, Y., Guennoun, R., Membrane progesterone receptors localization in the mouse spinal cord (2010) Neuroscience, 166, pp. 94-106
• Guennoun, R., Meffre, D., Labombarda, F., Gonzalez, S.L., Deniselle, M.C., Stein, D.G., De Nicola, A.F., Schumacher, M., The membrane-associated progesterone-binding protein 25-Dx: expression., cellular localization and up-regulation after brain and spinal cord injuries (2008) Brain Res Rev, 57, pp. 493-505
• Cai, W., Zhu, Y., Furuya, K., Li, Z., Sokabe, M., Chen, L., Two different molecular mechanisms underlying progesterone neuro-protection against ischemic brain damage (2008) Neuropharmacology, 55, pp. 127-138
• Garay, L., Deniselle, M.C., Lima, A., Roig, P., De Nicola, A.F., Effects of progesterone in the spinal cord of a mouse model of multiple sclerosis (2007) J Steroid Biochem Mol Biol, 107, pp. 228-237
• Garcia-Estrada, J., Luquin, S., Fernandez, A.M., Garcia-Segura, L.M., Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury (1999) Int J Dev Neurosci, 17, pp. 145-151
• Irwin, R.W., Yao, J., Hamilton, R.T., Cadenas, E., Brinton, R.D., Nilsen, J., Progesterone and estrogen regulate oxidative metabolism in brain mitochondria (2008) Endocrinology, 149, pp. 3167-3175
• Labombarda, F., Gonzalez, S.L., Lima, A., Roig, P., Guennoun, R., Schumacher, M., De Nicola, A.F., Effects of progesterone on oligodendrocyte progenitors., oligodendrocyte transcription factors., and myelin proteins following spinal cord injury (2009) Glia, 57, pp. 884-897
• Labombarda, F., Gonzalez, S., Lima, A., Roig, P., Guennoun, R., Schumacher, M., De Nicola, A.F., Progesterone attenuates astro-and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury (2011) Exp Neurol
• Ogata, T., Nakamura, Y., Tsuji, K., Shibata, T., Kataoka, K., Steroid hormones protect spinal cord neurons from glutamate toxicity (1993) Neuroscience, 55, pp. 445-449
• Boillee, S., Peschanski, M., Junier, M.P., The Wobbler mouse: a neurodegeneration jigsaw puzzle (2003) Mol Neurobiol, 28, pp. 65-106
• Dennis, J.S., Citron, B.A., Wobbler mice modeling motor neuron disease display elevated transactive response DNA binding protein (2009) Neuroscience, 158, pp. 745-750
• Cudkowicz, M.E., Brown, R.H., Amyotrophic lateral sclerosis and related motor neuron diseases (1998) Human Press, pp. 907-911
• Mitsumoto, H., Bradley, W.G., Murine motor neuron disease (the Wobbler mouse): degeneration and regeneration of the lower motor neuron (1982) Brain, 105, pp. 811-834
• González Deniselle, M.C., Lopez-Costa, J.J., Saavedra, J.P., Pietranera, L., Gonzalez, S.L., Garay, L., Guennoun, R., De Nicola, A.F., Progesterone neuroprotection in the Wobbler mouse., a genetic model of spinal cord motor neuron disease (2002) Neurobiol Dis, 11, pp. 457-468
• Hantaz-Ambroise, D., Jacque, C., Ait, I.A., Parmentier, C., Leclerc, P., Cambier, D., Zadigue, G., Rieger, F., Specific features of chronic astrocyte gliosis after experimental central nervous system (CNS) xenografting and in Wobbler neurological mutant CNS (2001) Differentiation, 69, pp. 100-107
• Laage, S., Zobel, G., Jockusch, H., Astrocyte overgrowth in the brain stem and spinal cord of mice affected by spinal atrophy., Wobbler (1988) Dev Neurosci, 10, pp. 190-198
• Clarke, P.G., Developmental cell death: morphological diversity and multiple mechanisms (1990) Anat Embryol (Berl), 181, pp. 195-213
• Dave, K.R., Bradley, W.G., Perez-Pinzon, M.A., Early mitochondrial dysfunction occurs in motor cortex and spinal cord at the onset of disease in the Wobbler mouse (2003) Exp Neurol, 182, pp. 412-420
• Santoro, B., Bigini, P., Levandis, G., Nobile, V., Biggiogera, M., Botti, F., Mennini, T., Curti, D., Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease (2004) Neurobiol Dis, 17, pp. 349-357
• Henderson, J.T., Javaheri, M., Kopko, S., Roder, J.C., Reduction of lower motor neuron degeneration in Wobbler mice by N-acetyl-L-cysteine (1996) J Neurosci, 16, pp. 7574-7582
• Ikeda, K., Iwasaki, Y., Kinoshita, M., Marubuchi, S., Ono, S., a novel neuroprotective agent., delays progression of neuromus-cular dysfunction in Wobbler mouse motoneuron disease (2000) Brain Res, 858, pp. 84-91
• Tsuzaka, K., Ishiyama, T., Pioro, E.P., Mitsumoto, H., Role of brain-derived neurotrophic factor in Wobbler mouse motor neuron disease (2001) Muscle Nerve, 24, pp. 474-480
• Clowry, G.J., McHanwell, S., Expression of nitric oxide synthase by motor neurones in the spinal cord of the mutant mouse Wobbler (1996) Neurosci Lett, 215, pp. 177-180
• González Deniselle, M.C., Garay, L., Gonzalez, S., Guennoun, R., Schumacher, M., De Nicola, A.F., Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease (2005) Exp Neurol, 195, pp. 518-523
• Carreras, M.C., Franco, M.C., Peralta, J.G., Poderoso, J.J., Nitric oxide., complex I., and the modulation of mitochondrial reactive species in biology and disease (2004) Mol Aspects Med, 25, pp. 125-139
• Yung, K.K., Tang, F., Fielding, R., Du, Y.H., Vacca-Galloway, L.L., Alteration in the levels of thyrotropin releasing hormone., substance P and enkephalins in the spinal cord., brainstem, hypothal-amus and midbrain of the Wobbler mouse at different stages of the motoneuron disease (1992) Neuroscience, 50, pp. 209-222
• Robertson, C.L., Puskar, A., Hoffman, G.E., Murphy, A.Z., Saraswati, M., Fiskum, G., Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats (2006) Exp Neurol, 197, pp. 235-243
• González Deniselle, M.C., Garay, L., Gonzalez, S., Saravia, F., Labombarda, F., Guennoun, R., Schumacher, M., De Nicola, A.F., Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons (2007) Exp Neurol, 203, pp. 406-414
• Matsumoto, T., Rauskolb, S., Polack, M., Klose, J., Kolbeck, R., Korte, M., Barde, Y.A., Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF., not pro-BDNF (2008) Nat Neurosci, 11, pp. 131-133
• Ishiyama, T., Ogo, H., Wong, V., Klinkosz, B., Noguchi, H., Nakayama, C., Mitsumoto, H., Methionine-free brain-derived neurotrophic factor in Wobbler mouse motor neuron disease: dose-related effects and comparison with the methionyl form (2002) Brain Res, 944, pp. 195-199
• Ishiyama, T., Okada, R., Nishibe, H., Mitsumoto, H., Nakayama, C., Riluzole slows the progression of neuromuscular dysfunction in the Wobbler mouse motor neuron disease (2004) Brain Res, 1019, pp. 226-236
• Nagappan, G., Lu, B., Activity-dependent modulation of the BDNF receptor TrkB: mechanisms and implications (2005) Trends Neurosci, 28, pp. 464-471
• Gulino, R., Lombardo, S.A., Casabona, A., Leanza, G., Perciavalle, V., Levels of brain-derived neurotrophic factor and neurotrophin-4 in lumbar motoneurons after low-thoracic spinal cord hemisec-tion (2004) Brain Res, 1013, pp. 174-181
• Beck, T., Lindholm, D., Castren, E., Wree, A., Brain-derived neu-rotrophic factor protects against ischemic cell damage in rat hippocampus (1994) J Cereb Blood Flow Metab, 14, pp. 689-692
• Chun, H.S., Son, J.J., Son, J.H., Identification of potential compounds promoting BDNF production in nigral dopaminergic neurons: clinical implication in Parkinson's disease (2000) Neuroreport, 11, pp. 511-514
• Giehl, K.M., Schutte, A., Mestres, P., Yan, Q., The survival-promoting effect of glial cell line-derived neurotrophic factor on axoto-mized corticospinal neurons in vivo is mediated by an endogenous brain-derived neurotrophic factor mechanism (1998) J Neurosci, 18, pp. 7351-7360
• Koda, M., Murakami, M., Ino, H., Yoshinaga, K., Ikeda, O., Hashimoto, M., Yamazaki, M., Moriya, H., Brain-derived neurotrophic factor suppresses delayed apoptosis of oligodendrocytes after spinal cord injury in rats (2002) J Neurotrauma, 19, pp. 777-785
• Bigini, P., Bastone, A., Mennini, T., Glutamate transporters in the spinal cord of the Wobbler mouse (2001) Neuroreport, 12, pp. 1815-1820
• Mitsumoto, H., Ikeda, K., Klinkosz, B., Cedarbaum, J.M., Wong, V., Lindsay, R.M., Arrest of motor neuron disease in Wobbler mice cotreated with CNTF and BDNF (1994) Science, 265, pp. 1107-1110
• Kato, T., Choline acetyltransferase activities in single spinal motor neurons from patients with amyotrophic lateral sclerosis (1989) J Neurochem, 52, pp. 636-640
• Oda, Y., Imai, S., Nakanishi, I., Ichikawa, T., Deguchi, T., Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis (1995) Pathol Int, 45, pp. 933-939
• Blondet, B., Barlovatz-Meimon, G., Festoff, B.W., Soria, C., Soria, J., Rieger, F., Hantai, D., Plasminogen activators in the neuro-muscular system of the Wobbler mutant mouse (1992) Brain Res, 580, pp. 303-310
• Meyer, M., Gonzalez Deniselle, M.C., Garay, L.I., Monachelli, G.G., Lima, A., Roig, P., Guennoun, R., De Nicola, A.F., Stage dependent effects of progesterone on motoneurons and glial cells of Wobbler mouse spinal cord degeneration (2010) Cell Mol Neurobiol, 30, pp. 123-135
• Bensimon, G., Lacomblez, L., Meininger, V., A controlled trial of riluzole in amyotrophic lateral sclerosis (1994) ALS/Riluzole Study Group. N Engl J Med, 330, pp. 585-591
• Bruijn, L.I., Miller, T.M., Cleveland, D.W., Unraveling the mechanisms involved in motor neuron degeneration in ALS (2004) Annu Rev Neurosci, 27, pp. 723-749
• Roof, R.L., Hall (2000) Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone., 17, pp. 367-388
• Stein, D.G., Brain damage., sex hormones and recovery: a new role for progesterone and estrogen? (2001) Trends Neurosci, 24, pp. 386-391
• Wright, D.W., Kellermann, A.L., Hertzberg, V.S., Clark, P.L., Frankel, M., Goldstein, F.C., Salomone, J.P., Hoffman, S.W., Stein DG. ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury (2007) Ann Emerg Med, 49, pp. 391-402
• Xiao, G., Wei, J., Yan, W., Wang, W., Lu, Z., Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial (2008) Crit Care, 12, p. R61
• Gargiulo Monachelli, G., Meyer, M., Rodriguez, G.E., Garay, L.I., Sica, R.E., De Nicola, A.F., Gonzalez Deniselle, M.C., Endogenous progesterone is associated to amyotrophic lateral sclerosis prognostic factors (2011) Acta Neurol Scand, 123, pp. 60-67
• Patacchioli, F.R., Monnazzi, P., Scontrini, A., Tremante, E., Caridi, I., Brunetti, E., Buttarelli, F.R., Pontieri, F.E., Adrenal dysregu-lation in amyotrophic lateral sclerosis (2003) J Endocrinol Invest
• Gonzalez Deniselle, M.C., Gonzalez, S.L., Piroli, G.G., Lima, A.E., De Nicola, A.F., The 21-aminosteroid U-74389F increases the number of glial fibrillary acidic protein-expressing astrocytes in the spinal cord of control and Wobbler mice (1996) Cell Mol Neurobiol, 16, pp. 61-72
• Genazzani, A.R., Petraglia, F., Bernardi, F., Casarosa, E., Salvestroni, C., Tonetti, A., Nappi, R.E., Luisi, M., Circulating levels of allopregnanolone in humans: gender., age, and endocrine influences (1998) J Clin Endocrinol Metab, 83, pp. 2099-2103
• Singh, M., Mechanisms of progesterone-induced neuroprotection (2005) Ann NY Acad Sci, 1052, pp. 145-151
• Mandrioli, J., Faglioni, P., Nichelli, P., Sola, P., Amyotrophic lateral sclerosis: prognostic indicators of survival (2006) Amyotroph Lateral Scler, 7, pp. 211-220
• Furuzawa-Carballeda, J., Vargas-Rojas, M.I., Cabral, A.R., Autoimmune inflammation from the Th17 perspective (2007) Autoimmun Rev, 6, pp. 169-175
• McQualter, J.L., Bernard, C.C., Multiple sclerosis: a battle between destruction and repair (2007) J Neurochem, 100, pp. 295-306
• Trapp, B.D., Nave, K.A., Multiple sclerosis: an immune or neurodegenerative disorder? (2008) Annu Rev Neurosci, 31, pp. 247-269
• Matute, C., Perez-Cerdá, F., Multiple sclerosis: novel perspectives on newly forming lesions (2005) Trends Neurosci, 28, pp. 173-175
• Druckmann, R., Druckmann, M.A., Progesterone and the immunology of pregnancy (2005) J Steroid Biochem Mol Biol, 97, pp. 389-396
• El Etr, M., Vukusic, S., Gignoux, L., Durand-Dubief, F., Achiti, I., Baulieu, E.E., Confavreux, C., Steroid hormones in multiple sclerosis (2005) J Neurol Sci, 233, pp. 49-54
• Hughes, M.D., Multiple sclerosis and pregnancy (2004) Neurol Clin, 22, pp. 757-769
• Leitner, H., Influence of neurosteroids on the pathogenesis of multiple sclerosis (2010) Med Hypotheses, 75, pp. 229-234
• Paterson, P.Y., Autoimmune diseases of myelin (1980) Prog Clin Biol Res, 49, pp. 19-36
• Sun, D., Zhang, Y., Wei, B., Peiper, S.C., Shao, H., Kaplan, H.J., Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules (2003) Int Immunol, 15, pp. 261-268
• Ayers, M.M., Hazelwood, L.J., Catmull, D.V., Wang, D., McKormack, Q., Bernard, C.C., Orian, J.M., Early glial responses in murine models of multiple sclerosis (2004) Neurochem Int, 45, pp. 409-419
• Garay, L., Gonzalez Deniselle, M.C., Gierman, L., Meyer, M., Lima, A., Roig, P., De Nicola, A.F., Steroid protection in the experimental autoimmune encephalomyelitis model of multiple sclerosis (2008) Neuroimmunomodulation, 15, pp. 76-83
• Penkowa, M., Hidalgo, J., Treatment with metallothionein prevents demyelination and axonal damage and increases oligodendrocyte precursors and tissue repair during experimental autoimmune encephalomyelitis (2003) J Neurosci Res, 72, pp. 574-586
• Giatti, S., D'Intino, G., Maschi, O., Pesaresi, M., Garcia-Segura, L.M., Calza, L., Caruso, D., Melcangi, R.C., Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neu-roactive steroid levels (2010) Neurochem Int, 56, pp. 118-127
• Onuki, M., Ayers, M.M., Bernard, C.C., Orian, J.M., Axonal degeneration is an early pathological feature in autoimmune-mediated demyelination in mice (2001) Microsc Res Tech, 52, pp. 731-739
• Garay, L., Deniselle, M.C., Meyer, M., Costa, J.J., Lima, A., Roig, P., De Nicola, A.F., Protective effects of progesterone administration on axonal pathology in mice with experimental autoimmune encephalomyelitis (2009) Brain Res, 1283, pp. 177-185
• Yates, M.A., Li, Y., Chlebeck, P., Proctor, T., Vandenbark, A.A., Offner, H., Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis (2010) J Neuroimmunol, 220, pp. 136-139
• Yu HJ, J., Chen, X.S., Cai, Q.Y., Liu, H.L., Liu, G.D., Yao, Z.X., Progesterone attenuates neurological behavioral deficits of experimental autoimmune encephalomyelitis through remyeli-nation with nucleus-sublocalized Olig1 protein (2010) Neurosci Lett, 476, pp. 42-45
• Garay, L., Tungler, V., Deniselle, M.C., Lima, A., Roig, P., De Nicola, A.F., Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cord (2011) Neuroscience, 192, pp. 588-597
• Confavreux, C., Hutchinson, M., Hours, M.M., Cortinovis-Tourniaire, P., Moreau, T., Rate of pregnancy-related relapse in multiple sclerosis (1998) Pregnancy in Multiple Sclerosis Group. N Engl J Med, 339, pp. 285-291
• Bebo, B.F., Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains (2001) J Immunol, 166, pp. 2080-2089
• Elloso, M.M., Phiel, K., Henderson, R.A., Harris, H.A., Adelman, S.J., Suppression of experimental autoimmune encephalomy-elitis using estrogen receptor-selective ligands (2005) J Endocrinol, 185, pp. 243-252
• Kim, S., Liva, S.M., Dalal, M.A., Verity, M.A., Voskuhl, R.R., Estriol ameliorates autoimmune demyelinating disease: implications for multiple sclerosis (1999) Neurology, 52, pp. 1230-1238
• Offner, H., Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis (2004) J Neurosci Res, 78, pp. 603-624

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------