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Abstract:

Aquaporins (AQPs) can be revisited from a distinct and complementary perspective: the outcome from analyzing them from both plant and animal studies. (1) The approach in the study. Diversity found in both kingdoms contrasts with the limited number of crystal structures determined within each group. While the structure of almost half of mammal AQPs was resolved, only a few were resolved in plants. Strikingly, the animal structures resolved are mainly derived from the AQP2-lineage, due to their important roles in water homeostasis regulation in humans. The difference could be attributed to the approach: relevance in animal research is emphasized on pathology and in consequence drug screening that can lead to potential inhibitors, enhancers and/or regulators. By contrast, studies on plants have been mainly focused on the physiological role that AQPs play in growth, development and stress tolerance. (2) The transport capacity. Besides the well-described AQPs with high water transport capacity, large amount of evidence confirms that certain plant AQPs can carry a large list of small solutes. So far, animal AQP list is more restricted. In both kingdoms, there is a great amount of evidence on gas transport, although there is still an unsolved controversy around gas translocation as well as the role of the central pore of the tetramer. (3) More roles than expected. We found it remarkable that the view of AQPs as specific channels has evolved first toward simple transporters to molecules that can experience conformational changes triggered by biochemical and/or mechanical signals, turning them also into signaling components and/or behave as osmosensor molecules. © 2017, International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany.

Registro:

Documento: Artículo
Título:Plant and animal aquaporins crosstalk: what can be revealed from distinct perspectives
Autor:Sutka, M.; Amodeo, G.; Ozu, M.
Filiación:Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires e Instituto de Biodiversidad y Biología Experimental, Universidad de Buenos Aires y Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
Palabras clave:Aquaporins; Diversity; Gases; Osmosensor; Solutes; aquaglyceroporin; aquaporin; aquaporin 1; aquaporin 10; aquaporin 11; aquaporin 12; aquaporin 2; aquaporin 3; aquaporin 4; aquaporin 5; aquaporin 6; aquaporin 7; aquaporin 8; aquaporin 9; arginine; carbon dioxide; epidermal growth factor; GlpF like intrinsic protein; glycerol transporter; hybrid intrinsic protein; hydrogen peroxide; hydroxyl radical; nodulin 26 like intrinsic protein; plasma membrane intrinsic protein; small basic intrinsic protein; superoxide; tonoplast intrinsic protein; uncategorized intrinsic protein; unclassified drug; unindexed drug; vasopressin; crystal structure; development; drug screening; gas transport; growth; homeostasis and regulation; human; hydraulic conductivity; nonhuman; pH; priority journal; protein expression; protein localization; regulatory mechanism; Review; stress; water transport
Año:2017
Volumen:9
Número:5
Página de inicio:545
Página de fin:562
DOI: http://dx.doi.org/10.1007/s12551-017-0313-3
Título revista:Biophysical Reviews
Título revista abreviado:Biophys. Rev.
ISSN:18672450
CAS:aquaporin, 215587-75-0; aquaporin 1, 146410-94-8, 149348-86-7; aquaporin 2, 231937-18-1; aquaporin 4, 175960-54-0; arginine, 1119-34-2, 15595-35-4, 7004-12-8, 74-79-3; carbon dioxide, 124-38-9, 58561-67-4; epidermal growth factor, 59459-45-9, 62229-50-9; hydrogen peroxide, 7722-84-1; hydroxyl radical, 3352-57-6; superoxide, 11062-77-4; vasopressin, 11000-17-2
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18672450_v9_n5_p545_Sutka

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Citas:

---------- APA ----------
Sutka, M., Amodeo, G. & Ozu, M. (2017) . Plant and animal aquaporins crosstalk: what can be revealed from distinct perspectives. Biophysical Reviews, 9(5), 545-562.
http://dx.doi.org/10.1007/s12551-017-0313-3
---------- CHICAGO ----------
Sutka, M., Amodeo, G., Ozu, M. "Plant and animal aquaporins crosstalk: what can be revealed from distinct perspectives" . Biophysical Reviews 9, no. 5 (2017) : 545-562.
http://dx.doi.org/10.1007/s12551-017-0313-3
---------- MLA ----------
Sutka, M., Amodeo, G., Ozu, M. "Plant and animal aquaporins crosstalk: what can be revealed from distinct perspectives" . Biophysical Reviews, vol. 9, no. 5, 2017, pp. 545-562.
http://dx.doi.org/10.1007/s12551-017-0313-3
---------- VANCOUVER ----------
Sutka, M., Amodeo, G., Ozu, M. Plant and animal aquaporins crosstalk: what can be revealed from distinct perspectives. Biophys. Rev. 2017;9(5):545-562.
http://dx.doi.org/10.1007/s12551-017-0313-3